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Journal Articles

The MCP-1/CCR2 Axis in the Biology of Acute Myeloid Leukemia: Possible Role in Blast Cell Migration

Pablo A. Ramirez, MD, Patricia Macanas, PhD, Leonardo Navarrete, Thomas Quezada, Richard Broekhuisen, Bruno Nervi, MD

Blood (2012) 120 (21): 1439.

https://doi.org/10.1182/blood.V120.21.1439.1439

Published: 2012

Journal Articles

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

Bruno Nervi, Pablo Ramirez, Michael P. Rettig, Geoffrey L. Uy, Matthew S. Holt, Julie K. Ritchey, Julie L. Prior, David Piwnica-Worms, Gary Bridger, Timothy J. Ley, John F. DiPersio

Blood (2009) 113 (24): 6206–6214.

https://doi.org/10.1182/blood-2008-06-162123

Published: 2009

Includes: Supplemental data

Journal Articles

Kinetics of Human and Murine Mobilization of Acute Myeloid Leukemia in Response to AMD3100.

Geoffrey L. Uy, MD, Michael P. Rettig, Ph.D., Pablo Ramirez, M.D., Bruno Nervi, M.D., Camille N. Abboud, M.D., John F. DiPersio, M.D., Ph.D.

Blood (2007) 110 (11): 867.

https://doi.org/10.1182/blood.V110.11.867.867

Published: 2007

Journal Articles

In Vivo Bioluminescence Imaging (BLI) and Sequential 18 F]FHBG microPET Imaging Studies of Human T Cell (huT) Trafficking, Expansion and Xenogeneic Graft-Versus-Host-Disease (XGVHD) Following Different Routes of T Cell Administration.

Bruno Nervi, MD, Michael P. Rettig, PhD, Julie K. Ritchey, Hanlin L. Wang, MD,PhD, Gerhard Bauer, Jon Walker, Julie L. Prior, David Piwnica-Worms, MD,PhD, Jan A. Nolta, PhD, John F. DiPersio, MD,PhD

Blood (2006) 108 (11): 5178.

https://doi.org/10.1182/blood.V108.11.5178.5178

Published: 2006

Journal Articles

CXCR4/SDF-1 Is a Key Regulator for Leukemia Migration and Homing to the BM: Impact of AMD3100 on In Vivo Response to Chemotherapy.

Bruno Nervi, MD, Pablo Ramirez, MD, Matthew Holt, Michael P. Rettig, PhD, Julie K. Ritchey, Julie L. Prior, David Piwnica-Worms, MD,PhD, Gary Bridger, PhD, Timothy J. Ley, MD,PhD, John F. DiPersio, MD,PhD

Blood (2006) 108 (11): 569.

https://doi.org/10.1182/blood.V108.11.569.569

Published: 2006

Journal Articles

Salvage Therapy with Flag/Idarubicin/Mylotarg (Flag-IM) Results in a Superior CR/CRp Rate and Low Toxicity When Compared to Mitoxantrone/Etoposide/Cytarabine (MEC) in Patients with Relapsed and Refractory AML.

Brian A. Van Tine, MD, PhD, Kristan M. Augustin, Ph.D., David I. Kuperman, M.D., Bruno Nervi, M.D., Peter Westervelt, M.D./Ph.D., John F. DiPersio, M.D./Ph.D.

Blood (2006) 108 (11): 4576.

https://doi.org/10.1182/blood.V108.11.4576.4576

Published: 2006

Journal Articles

AMD3100 Mobilizes Acute Promyelocytic Leukemia Cells from the Bone Marrow into the Peripheral Blood and Sensitizes Leukemia Cells to Chemotherapy.

Bruno Nervi, MD, Matthew Holt, Michael P. Rettig, PhD, Gary Bridger, PhD, Timothy J. Ley, MD, PhD, John F. DiPersio, MD, PhD

Blood (2005) 106 (11): 246.

https://doi.org/10.1182/blood.V106.11.246.246

Published: 2005

Journal Articles

Naive and Ex Vivo Activated Human T Cells Generate Consistent Engraftment and Lethal Graft-Versus-Host Disease (GvHD) in NOD SCID β 2M Null Mice: A New Xenogeneic Model for GvHD.

Bruno Nervi, MD, Michael P. Rettig, PhD, Julie K. Ritchey, Gerhard Bauer, Jon Walker, Dave Hess, PhD, Phillip E. Herrbrich, Mark Bonyhadi, PhD, Ronald J. Berenson, MD, Jan A. Nolta, PhD, John F. DiPersio, MD, PhD

Blood (2005) 106 (11): 3106.

https://doi.org/10.1182/blood.V106.11.3106.3106

Published: 2005

Journal Articles

Kinetics of Hematopoietic Progenitor Cell Mobilization with Cyclophosphamide or Cyclophosphamide Plus AMD3100 Using a Mouse Model.

Bill Q. Gai, MD, PhD, Matthew S. Holt, Bruno Nervi, MD, Michael P. Rettig, PhD, Julie K. Ritchey, Gary Bridger, PhD, John F. DiPersio, MD, PhD

Blood (2005) 106 (11): 5217.

https://doi.org/10.1182/blood.V106.11.5217.5217

Published: 2005

Journal Articles

Large Scale Ex Vivo GMP Expanded, Activated Human T Cells Consistently Induce Lethal GvHD in a Mouse Xenotransplant Model - A New Way To Study Treatments for Acute GvHD.

Gerhard Bauer, Jon Walker, Bruno Nervi, Julie Ritchey, Jackie Hughes, Bill Eades, Mark Bonyhadi, Jan Nolta, John F. DiPersio

Blood (2005) 106 (11): 5242.

https://doi.org/10.1182/blood.V106.11.5242.5242

Published: 2005

Journal Articles

A Murine Xenograft Model for Human T Cell Mediated Graft Versus Host Disease.

Bruno Nervi, MD, Michael Rettig, PhD, Julie Ritchey, Jon Walker, Gerhard Bauer, Phillip Herrbrich, Jan A. Nolta, PhD, John F. DiPersio, Md/PhD

Blood (2004) 104 (11): 4977.

https://doi.org/10.1182/blood.V104.11.4977.4977

Published: 2004

Journal Articles

In Vivo Suicide Gene Therapy of Human T Lymphocytes To Prevent Graft Versus Host Disease in a Murine Xenograft Model.

Bruno Nervi, MD, Michael Rettig, PhD, Julie Ritchey, Jon Walker, Gerhard Bauer, Philip Herrbrich, Mark L. Bonyhadi, PhD, Jan A. Nolta, PhD, John F. DiPersio, MD/PhD

Blood (2004) 104 (11): 4979.

https://doi.org/10.1182/blood.V104.11.4979.4979

Published: 2004

Journal Articles

Comparison of the Division Rate and Proliferative Capacity of Naive and Ex Vivo Activated T Cells after Allogeneic Bone Marrow Transplantation.

Michael P. Rettig, Ph.D., Julie K. Ritchey, Bruno Nervi, M.D., Mark L. Bonyhadi, Ph.D., John F. DiPersio, M.D./Ph.D.

Blood (2004) 104 (11): 2133.

https://doi.org/10.1182/blood.V104.11.2133.2133

Published: 2004

NARROW

The MCP-1/CCR2 Axis in the Biology of Acute Myeloid Leukemia: Possible Role in Blast Cell Migration

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

Kinetics of Human and Murine Mobilization of Acute Myeloid Leukemia in Response to AMD3100.

In Vivo Bioluminescence Imaging (BLI) and Sequential 18 F]FHBG microPET Imaging Studies of Human T Cell (huT) Trafficking, Expansion and Xenogeneic Graft-Versus-Host-Disease (XGVHD) Following Different Routes of T Cell Administration.

CXCR4/SDF-1 Is a Key Regulator for Leukemia Migration and Homing to the BM: Impact of AMD3100 on In Vivo Response to Chemotherapy.

Salvage Therapy with Flag/Idarubicin/Mylotarg (Flag-IM) Results in a Superior CR/CRp Rate and Low Toxicity When Compared to Mitoxantrone/Etoposide/Cytarabine (MEC) in Patients with Relapsed and Refractory AML.

AMD3100 Mobilizes Acute Promyelocytic Leukemia Cells from the Bone Marrow into the Peripheral Blood and Sensitizes Leukemia Cells to Chemotherapy.

Naive and Ex Vivo Activated Human T Cells Generate Consistent Engraftment and Lethal Graft-Versus-Host Disease (GvHD) in NOD SCID β 2M Null Mice: A New Xenogeneic Model for GvHD.

Kinetics of Hematopoietic Progenitor Cell Mobilization with Cyclophosphamide or Cyclophosphamide Plus AMD3100 Using a Mouse Model.

Large Scale Ex Vivo GMP Expanded, Activated Human T Cells Consistently Induce Lethal GvHD in a Mouse Xenotransplant Model - A New Way To Study Treatments for Acute GvHD.

A Murine Xenograft Model for Human T Cell Mediated Graft Versus Host Disease.

In Vivo Suicide Gene Therapy of Human T Lymphocytes To Prevent Graft Versus Host Disease in a Murine Xenograft Model.

Comparison of the Division Rate and Proliferative Capacity of Naive and Ex Vivo Activated T Cells after Allogeneic Bone Marrow Transplantation.

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American Society of Hematology

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American Society of Hematology

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