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Brian R. Bettencourt
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Journal Articles

Aln-TMP: A Subcutaneously Administered RNAi Therapeutic Targeting Tmprss6 For The Treatment Of β-Thalassemia

James Butler, PhD, Shannon Fishman, BS, Tim Racie, BS, Julia Hettinger, BS, Brian R Bettencourt, PhD, Klaus Charisse, PhD, Kevin Fitzgerald, PhD
Journal: Blood
Blood (2013) 122 (21): 2260.
https://doi.org/10.1182/blood.V122.21.2260.2260
Published: 2013
Journal Articles

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe −/− mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia

Paul J. Schmidt, Iva Toudjarska, Anoop K. Sendamarai, Tim Racie, Stuart Milstein, Brian R. Bettencourt, Julia Hettinger, David Bumcrot, Mark D. Fleming
Journal: Blood
Blood (2013) 121 (7): 1200–1208.
https://doi.org/10.1182/blood-2012-09-453977
Published: 2013
Includes: Supplemental data
Journal Articles

Targeting the Hepcidin Pathway with RNAi Therapeutics for the Treatment of Anemia

Akin Akinc, PhD, Amy Chan-Daniels, PhD, Alfica Sehgal, PhD, Don Foster, Brian R Bettencourt, PhD, Julia Hettinger, Tim Racie, Justin Aubin, Satya Kuchimanchi, PhD, Hila Epstein-Barash, PhD, Tomoko Nakayama, PhD
Journal: Blood
Blood (2011) 118 (21): 688.
https://doi.org/10.1182/blood.V118.21.688.688
Published: 2011
Journal Articles

RNAi-Mediated Inhibition of Activated Protein C- A New Approach for Hemophilia Treatment

Ivanka Toudjarska, PhD, Zuhua Cai, Tim Racie, Julia Hettinger, Stuart Milstein, PhD, Brian R Bettencourt, PhD, Dinah WY Sah, PhD, David Bumcrot, PhD, John Maraganore, PhD, Akshay Vaishnaw, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1204.
https://doi.org/10.1182/blood.V118.21.1204.1204
Published: 2011
Journal Articles

RNAi-Mediated Inhibition of Tmprss6 Elevates Hamp1 Expression and Reduces Serum Iron Levels in Mice

Ivanka Toudjarska, PhD, Zuhua Cai, Tim Racie, Stuart Milstein, PhD, Brian R Bettencourt, PhD, Julia Hettinger, Dinah WY Sah, PhD, Akshay Vaishnaw, MD, PhD, David Bumcrot, PhD
Journal: Blood
Blood (2011) 118 (21): 1045.
https://doi.org/10.1182/blood.V118.21.1045.1045
Published: 2011