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Journal Articles

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Fabienne Kunz, Katarina Reinhardt, PhD, Nils Von Neuhoff, PhD, Karl Welte, MD, Dirk Reinhardt, MD PhD, Basant Kumar Thakur, PhD
Journal: Blood
Blood (2016) 128 (22): 1711.
https://doi.org/10.1182/blood.V128.22.1711.1711
Published: 2016
Journal Articles

Acetylation of p53 Is Involved in Valproic Acid Induced Death of AML Cells

Basant Kumar Thakur, PhD, Tino Dittrich, Karl Welte, MD, Jan-Henning Klusmann, MD, Dirk Reinhardt, MD
Journal: Blood
Blood (2011) 118 (21): 2461.
https://doi.org/10.1182/blood.V118.21.2461.2461
Published: 2011
Journal Articles

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

Metodi V. Stankov, PhD, Kirsten Heitmann, Zhe Li, PhD, Basant Kumar Thakur, PhD, Diana Panayotova-Dimitrova, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Tino Dittrich, Stephan Emmrich, Nora Schweitzer, MD, Martin Leverkus, MD, Dirk Reinhardt, MD, PhD, Stuart H. Orkin, MD, Georg M.N. Behrens, MD, Jan-Henning Klusmann, MD
Journal: Blood
Blood (2011) 118 (21): 3614.
https://doi.org/10.1182/blood.V118.21.3614.3614
Published: 2011
Journal Articles

Acetylation of p53 Protein Is Crucial for Its Function In Myeloid Cells.

Basant Kumar Thakur, PhD, Tino Dittrich, Mr, Julia Skokowa, Dr, Karl Welte, MD
Journal: Blood
Blood (2010) 116 (21): 1480.
https://doi.org/10.1182/blood.V116.21.1480.1480
Published: 2010
Journal Articles

Gene Expression-Based Chemical Genomics Identifies Valproic Acid to Revert the Oncogenic Effect of GATA1s In Down Syndrome Megakaryoblastic Leukemia.

Kirsten Heitmann, Zhe Li, PhD, Jan-Henning Klusmann, MD, Basant Kumar Thakur, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Stuart H. Orkin, MD, Dirk Reinhardt, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3646.
https://doi.org/10.1182/blood.V116.21.3646.3646
Published: 2010
Journal Articles

Nicotinamide Phosphoribosyltransferase (Nampt) Induces NAD + / SIRT1 Mediated Deacetylation of FOXO3a in Myeloid Cells.

Yannick Lippka, Basant Kumar Thakur, Julia Skokowa, Karl Welte
Journal: Blood
Blood (2009) 114 (22): 1352.
https://doi.org/10.1182/blood.V114.22.1352.1352
Published: 2009
Journal Articles

Nicotinamide Phosphoribosyltransferase (Nampt) Induces NAD + / SIRT1 Mediated Deacetylation of p53 in Myeloid Cells.

Basant Kumar Thakur, Yannick Lippka, Julia Skokowa, Karl Welte
Journal: Blood
Blood (2009) 114 (22): 3589.
https://doi.org/10.1182/blood.V114.22.3589.3589
Published: 2009
Journal Articles

Neutrophil elastase is severely down-regulated in severe congenital neutropenia independent of ELA2 or HAX1 mutations but dependent on LEF-1

Julia Skokowa, John Paul Fobiwe, Lan Dan, Basant Kumar Thakur, Karl Welte
Journal: Blood
Blood (2009) 114 (14): 3044–3051.
https://doi.org/10.1182/blood-2008-11-188755
Published: 2009
Journal Articles

The in Vivo Response of Patients Suffering from Severe Congenital Neutropenia (CN) to G-CSF Is Due to “Emergency” Granulopoiesis Induced by C/EBPβ

Lan Dan, Basant Kumar Thakur, Julia Skokowa, Karl Welte
Journal: Blood
Blood (2008) 112 (11): 315.
https://doi.org/10.1182/blood.V112.11.315.315
Published: 2008