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Andrew J. Coombs
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Journal Articles

Bone Marrow Failure and Developmental Delay Caused By Mutations in Poly(A)-Specific Ribonuclease

Free
Santhosh Dhanraj, MSc, Sethu Madhava Rao Gunja, MSc, Adam P Deveau, BScH, MSc, Mikael Nissbeck, MSc, Boonchai Boonyawat, MD, Andrew J Coombs, BScH, Alessandra Renieri, MD, Mafalda Mucciolo, MD, Annabella Marozza, MD, Sabrina Buoni, Lesley Turner, MD, Hongbing Li, PhD, Ameer Jarrar, MSc, Mathura Sabanayagam, BSc, Melanie Kirby, MD, Mary Shago, PhD, Dalila Pinto, PhD, Jason N. Berman, MD, Stephen W. Scherer, PhD FRSC, Anders Virtanen, PhD, Yigal Dror, MD FRCP(C)
Journal: Blood
Blood (2015) 126 (23): 2404.
https://doi.org/10.1182/blood.V126.23.2404.2404
Published: 2015
Journal Articles

The Zebrafish Provides Mechanistic Insights into the Role of Poly(A)-Specific Ribonuclease ( PARN ) in Hematopoietic Stem Cell (HSC) Homeostasis and Bone Marrow Failure

Free
Adam P Deveau, BScH, MSc, Andrew J Coombs, BScH, Santhosh Dhanraj, BSc, MSc, Gretchen Wagner, BScH, Yigal Dror, MD FRCP(C), Jason N. Berman, MD
Journal: Blood
Blood (2015) 126 (23): 668.
https://doi.org/10.1182/blood.V126.23.668.668
Published: 2015
Journal Articles

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Free
Adam Deveau, BSc, MSc, Alexander Michael Forrester, BSc, PhD, Andrew J Coombs, BScH, Gretchen S Wagner, BScH, Clemens Grabher, PhD, Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Matthew Mingay, BSc, Martin Hirst, PhD, A. Thomas Look, MD, Jason N. Berman, MD
Journal: Blood
Blood (2014) 124 (21): 436.
https://doi.org/10.1182/blood.V124.21.436.436
Published: 2014
Journal Articles

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Free
Jason N Berman, MD, Pedro Fernandez-Murray, PhD, Gheyath Nasrallah, PhD, Noelia Dufay, PhD, Conrad V Fernandez, FRCPC, BSc, MD, Ameer Jarrar, MSc, Andrew J Coombs, BSc(Hon), Christopher McMaster, PhD
Journal: Blood
Blood (2012) 120 (21): 2087.
https://doi.org/10.1182/blood.V120.21.2087.2087
Published: 2012
Journal Articles

Epigenetic Therapy Inhibits NUP98-HOXA9 -Mediated Myeloid Disease – Decitabine and Valproic Acid Work Synergistically to Rescue Normal Hematopoiesis in Transgenic Zebrafish.

Free
Adam Deveau, BSc(Hons), A. Michael Forrester, PhD, Clemens Grabher, Andrew J Coombs, BSc(Hon), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, A. Thomas Look, M.D., Jason N Berman, MD
Journal: Blood
Blood (2012) 120 (21): 2391.
https://doi.org/10.1182/blood.V120.21.2391.2391
Published: 2012
Journal Articles

The zebrafish reveals dependence of the mast cell lineage on Notch signaling in vivo

Free
Sahar I. Da'as, Andrew J. Coombs, Tugce B. Balci, Chloe A. Grondin, Adolfo A. Ferrando, Jason N. Berman
Journal: Blood
Blood (2012) 119 (15): 3585–3594.
https://doi.org/10.1182/blood-2011-10-385989
Published: 2012
Includes: Supplemental data
Journal Articles

Using the Zebrafish As a Tool for Modeling Systemic Mastocytosis,

Free
Tugce B Balci, MD, Andrew J Coombs, BSc(Hon), Chloe Grondin, Sahar I Da'as, MSc, Ian Chute, MSc, Daniel Leger, MSc, Adolfo A. Ferrando, MD, PhD, Stephen Lewis, PhD, Jason N Berman, MD
Journal: Blood
Blood (2011) 118 (21): 3208.
https://doi.org/10.1182/blood.V118.21.3208.3208
Published: 2011
Journal Articles

NUP98-HOXA9 drives High-Risk Myeloid Disease in Zebrafish – An In Vivo platform to Study Interacting Genes and Perform Drug Discovery,

Free
A. Michael Forrester, BSc(Hon), Andrew J Coombs, BSc(Hon), Eileen R McBride, MD, FRCP(C), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Clemens Grabher, PhD, Thomas Look, MD, Jason N Berman, MD
Journal: Blood
Blood (2011) 118 (21): 3622.
https://doi.org/10.1182/blood.V118.21.3622.3622
Published: 2011