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Journal Articles

Cellular Immune Responses To Vector In a Gene Therapy Trial For Hemophilia B Using An AAV8 Self-Complementary Factor IX Vector

Etiena Basner-Tschakarjan, MD PhD, Federico Mingozzi, PhD, Yifeng Chen, MD, Amit Nathwani, MD, PhD, Edward Tuddenham, MD, Anne Riddell, BSc, Catherine Ng, MS, Pradip Rustagi, MD, Bertil Glader, MD, PhD, Mark Kay, MD, PhD, Ulrike M. Reiss, MD, Arthur W. Nienhuis, MD, Andrew Davidoff, MD, Katherine A. High, MD
Journal: Blood
Blood (2013) 122 (21): 717.
https://doi.org/10.1182/blood.V122.21.717.717
Published: 2013
Journal Articles

Stable Factor IX Activity Following AAV-Mediated Gene Transfer in Patients with Severe Hemophilia B

Andrew Davidoff, MD, Edward GD Tuddenham, MBBS, FRCP, FRCPath, PhD, Savita Rangarajan, MBBS, FRCP, FRCPath, Cecilia Rosales, PhD, Jenny McIntosh, PhD, Pratima Chowdary, MBBS, FRCP, FRCPath, Anne Riddell, BSc, Bertil Glader, MD, PhD, Pradip Rustagi, MD, Catherine Ng, MS, Mark Kay, MD, PhD, Junfang Zhou, MD, Yunyu Spence, PhD, Christopher Morton, B.S., James Allay, PhD, Susan Sleep, PhD, Etiena Basner-Tschakarjan, MD, Federico Mingozzi, PhD., Katherine A. High, MD, John T. Gray, PhD, Ulrike M. Reiss, MD, Arthur W. Nienhuis, MD, Amit C Nathwani, MBChB, FRCP, FRCPath, PhD
Journal: Blood
Blood (2012) 120 (21): 752.
https://doi.org/10.1182/blood.V120.21.752.752
Published: 2012
Journal Articles

Adeno-Associated Viral Vector Mediated Gene Transfer for Hemophilia B

Amit C Nathwani, MBChB, FRCP, FRCPath, PhD, Edward GD Tuddenham, MBBS, FRCP, FRCPath, PhD, Savita Rangarajan, MBBS, FRCP, FRCPath, Cecilia Rosales, PhD, Jenny H McIntosh, PhD, David C Linch, MD FMedSci, Pratima Chowdary, MBBS, FRCP, FRCPath, Anja Griffioen, Anne Riddell, BSc, Jun Pie, BSN, Chris Harrington, BSN, James O’Beirne, MBBS, FRCP, MD EDIC, Keith Smith, BSc, MSc, C.Biol, John Pasi, MBChB, PhD, FRCP, FRCPath, Bertil Glader, MD PhD, Pradip Rustagi, MD, Catherine Ng, MS, Mark Kay, MD, PhD, Junfang Zhou, MD, Yunyu Spence, PhD, Christopher Morton, BS, James Allay, PhD, John Coleman, Susan Sleep, PhD, John M Cunningham, MD, Etiena Basner-Tschakarjan, MD, Federico Mingozzi, PhD, Katherine A. High, MD, John T. Gray, PhD, Ulrike M. Reiss, MD, Arthur W. Nienhuis, MD, Andrew Davidoff, MD
Journal: Blood
Blood (2011) 118 (21): 5.
https://doi.org/10.1182/blood.V118.21.5.5
Published: 2011
Journal Articles

Assessing the Potential of Perinatal Gene Transfer Using Congenital Factor VII Deficiency as a Model System

Christopher J Binny, Jenny H McIntosh, Edward Tuddenham, MD, Simon Waddington, Suzanne Buckley, Adrian Thrasher, John T. Gray, PhD, Amit Nathwani, MD, PhD, Alice F Tarantal, PhD, Andrew Davidoff
Journal: Blood
Blood (2010) 116 (21): 247.
https://doi.org/10.1182/blood.V116.21.247.247
Published: 2010
Journal Articles

Early Clinical Trial Results Following Administration of a Low Dose of a Novel Self Complementary Adeno-Associated Viral Vector Encoding Human Factor IX In Two Subjects with Severe Hemophilia B

Amit Nathwani, MD, PhD, Edward Tuddenham, MD, Cecilia Rosales, Jenny McIntosh, Anne Riddell, Pradip Rustagi, Bertil Glader, Mark Kay, MD, PhD, James Allay, PhD, John Coleman, Susan Sleep, Katherine A. High, MD, Federico Mingozzi, PhD., John T. Gray, PhD, Ulrike M. Reiss, MD, Arthur W. Nienhuis, MD, Andrew Davidoff
Journal: Blood
Blood (2010) 116 (21): 248.
https://doi.org/10.1182/blood.V116.21.248.248
Published: 2010
Journal Articles

Stable High Level Coagulation Factor VIII Expression In Vivo Following Gene Transfer Using a Novel Expression Cassette Encoding a More Potent FVIII Variant

Jenny McIntosh, Peter J Lenting, Edward Tuddenham, MD, Motunrayo Sotannde, Simon Waddington, John T. Gray, PhD, Andrew Davidoff, Amit Nathwani, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 250.
https://doi.org/10.1182/blood.V116.21.250.250
Published: 2010
Journal Articles

Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma

Clinical Trials & Observations
Raphaël F. Rousseau, Ann E. Haight, Charlotte Hirschmann-Jax, Eric S. Yvon, Donna R. Rill, Zhuyong Mei, Susan C. Smith, Shannon Inman, Kristine Cooper, Pat Alcoser, Bambi Grilley, Adrian Gee, Edwina Popek, Andrew Davidoff, Laura C. Bowman, Malcolm K. Brenner, Douglas Strother
Journal: Blood
Blood (2003) 101 (5): 1718–1726.
https://doi.org/10.1182/blood-2002-08-2493
Published: 2003
Journal Articles

Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA

Amit C. Nathwani, Andrew Davidoff, Hideki Hanawa, Jun-Fang Zhou, Elio F. Vanin, Arthur W. Nienhuis
Journal: Blood
Blood (2001) 97 (5): 1258–1265.
https://doi.org/10.1182/blood.V97.5.1258
Published: 2001