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Journal Articles

Negative Prognostic Relevance of a Specific 3-Gene Cluster in Myelodysplastic Syndromes during Azacitidine and Lenalidomide Therapy

Blood (2018) 132 (Supplement 1): 4347.

https://doi.org/10.1182/blood-2018-99-112062

Published: 2018

Journal Articles

Comparison of Two Different Therapeutic Regimens with Azacitidine and Lenalidomide (Combined versus Sequential) in Higher-Risk Myelodysplastic Syndromes. Update of Long-Term Results of a Randomized Phase II Multicenter Study

Blood (2018) 132 (Supplement 1): 4365.

https://doi.org/10.1182/blood-2018-99-117714

Published: 2018

Journal Articles

Proteome Analyses and Single-Cell RNA Sequencing Reveal Age-Dependent Re-Wiring of Central Carbon Metabolism in Myeloid-Biased Subsets of Human Hematopoietic Stem Cells

Marco L Hennrich, PhD, Natalie Romanov, Patrick Horn, PhD, Samira Jaeger, PhD, Volker Eckstein, PhD, Laura Poisa-Beiro, PhD, Jacqueline Boultwood, PhD, Thomas Luft, MD PhD, Andrea Pellagatti, PhD, Peer Bork, PhD, Patrick Aloy, PhD, Anne-Claude Gavin, PhD, Anthony D. Ho, MD FRCPC

Blood (2018) 132 (Supplement 1): 873.

https://doi.org/10.1182/blood-2018-99-110787

Published: 2018

Journal Articles

RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

Elina K Cook, MSc, Richard N Armstrong, PhD, Eshita Sharma, PhD, Brooke Snetsinger, MSc, Jacqueline Boultwood, PhD, Rena Buckstein, MD FRCPC, Andrea Pellagatti, PhD, Michael J. Rauh, MD PhD

Blood (2018) 132 (Supplement 1): 3843.

https://doi.org/10.1182/blood-2018-99-116128

Published: 2018

Journal Articles

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Blood (2018) 132 (Supplement 1): 107.

https://doi.org/10.1182/blood-2018-99-118747

Published: 2018

Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD

Blood (2017) 130 (Supplement 1): 785.

https://doi.org/10.1182/blood.V130.Suppl_1.785.785

Published: 2017

Journal Articles

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Blood (2017) 130 (Supplement 1): 2497.

https://doi.org/10.1182/blood.V130.Suppl_1.2497.2497

Published: 2017

Journal Articles

Gene Mutations and microRNA Signature in Myelodysplastic Syndromes during Azacitidine and Lenalidomide Therapy

Matilde Y Follo, PhD, Andrea Pellagatti, PhD, Richard N Armstrong, PhD, Stefano Ratti, MD, Sara Mongiorgi, PhD, Annalisa Astolfi, PhD, Valentina Indio, PhD, Cristina Clissa, MD PhD, Domenico Russo, MD, Marco Gobbi, MD, Marilena Barraco, PhD, Sarah Parisi, MD PhD, Andrea Pession, MD, Michele Cavo, MD, Lucia Manzoli, MD, Lucio Cocco, MD, Jacqueline Boultwood, PhD, Carlo Finelli, MD

Blood (2017) 130 (Supplement 1): 5299.

https://doi.org/10.1182/blood.V130.Suppl_1.5299.5299

Published: 2017

Journal Articles

Targeting MDS and AML Stem Cells with AZD-9150 Mediated Inhibition of STAT3

Blood (2016) 128 (22): 4314.

https://doi.org/10.1182/blood.V128.22.4314.4314

Published: 2016

Journal Articles

Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations

Christian Scharenberg, MD, Petter S. Woll, PhD, Valentina Giai, MD PhD, Andrea Pellagatti, PhD, Leonie Saft, MD PhD, Marios Dimitriou, Martin Jädersten, Monika Jansson, Iyadh Douagi, PhD, Donna S. Neuberg, ScD, Mohsen Karimi, Katarina Le Blanc, MD, PhD, Jacqueline Boultwood, PhD, Sten Eirik Jacobsen, MD PhD, Eva Hellstrom-Lindberg, MD PhD

Blood (2016) 128 (22): 4329.

https://doi.org/10.1182/blood.V128.22.4329.4329

Published: 2016

Journal Articles

Molecular and Clinical Characterization of Patients with Myeloid Neoplasms Carrying the 12p Deletion

Vera Adema, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Francesc Sole, PhD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 2007.

https://doi.org/10.1182/blood.V128.22.2007.2007

Published: 2016

Journal Articles

Combined DNA and Transcriptome Sequencing Reveals Discrete Subtypes of Myelodysplasia

Yusuke Shiozawa, MD, Luca Malcovati, MD, Anna Gallì, Andrea Pellagatti, PhD, Hiromichi Suzuki, MD PhD, Tetsuichi Yoshizato, MD PhD, Yusuke Sato, MD PhD, Keisuke Kataoka, MD PhD, Kenichi Yoshida, MD PhD, Kenichi Yoshida, MD PhD, Masashi Sanada, MD PhD, Hideki Makishima, MD PhD FACP, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Satoru Miyano, PhD, Jacqueline Boultwood, PhD, Eva Hellström-Lindberg, MD PhD, Seishi Ogawa, MD PhD, Mario Cazzola, MD

Blood (2016) 128 (22): 1974.

https://doi.org/10.1182/blood.V128.22.1974.1974

Published: 2016

Journal Articles

Lineage-Specific Aberrant mRNA Splicing By U2AF1 Mutation Alters Erythroid and Granulomonocytic Differentiation

Bon Ham Yip, PhD, Swagata Roy, PhD, Hamid Dolatshad, PhD, Jacqueline Shaw, Seishi Ogawa, MD PhD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD

Blood (2015) 126 (23): 142.

https://doi.org/10.1182/blood.V126.23.142.142

Published: 2015

Journal Articles

Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee

Blood (2015) 126 (23): 907.

https://doi.org/10.1182/blood.V126.23.907.907

Published: 2015

Journal Articles

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Blood (2015) 126 (23): 710.

https://doi.org/10.1182/blood.V126.23.710.710

Published: 2015

Journal Articles

Identification of a Prognostic Gene Expression Signature for AZA Response in MDS and CMML Patients

Blood (2014) 124 (21): 4601.

https://doi.org/10.1182/blood.V124.21.4601.4601

Published: 2014

Journal Articles

Efficacy of Dual Inhibition of p38 Mitogen Activated Protein Kinase (MAPK) and Tie-2 Kinase in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Blood (2014) 124 (21): 4628.

https://doi.org/10.1182/blood.V124.21.4628.4628

Published: 2014

Journal Articles

Aberration Of SF3B1 Results In Deregulated Splicing Of Key Genes and Pathways In Myelodysplastic Syndromes

Hamid Dolatshad, PhD, Marta Fernandez-Mercado, PhD, Bon Ham Yip, PhD, Chris J Smith, PhD, Martin Attwood, BSc, MRes, Cristina Di Genua, BSc, Natasha Sahgal, PhD, Bartlomiej P Przychodzen, PhD, Elli Papaemmanuil, PhD, Alexander A Kanapin, PhD, Helen Lockstone, PhD, Peter J. Campbell, PhD, Jaroslaw P. Maciejewski, MD, PhD, Andrea Pellagatti, PhD, Jacqueline Boultwood

Blood (2013) 122 (21): 2747.

https://doi.org/10.1182/blood.V122.21.2747.2747

Published: 2013

Journal Articles

Association Between Gene Expression Profiles and Commonly Mutated Genes In The Hematopoietic Stem Cells Of Patients With Myelodysplastic Syndromes

Andrea Pellagatti, PhD, Moritz Gerstung, PhD, Elli Papaemmanuil, PhD, Luca Malcovati, MD, Aristoteles Giagounidis, MD, PhD, Matteo G Della Porta, MD, Martin Jadersten, MD, PhD, Amit Verma, MD, Paresh Vyas, MD, PhD, Sally Killick, MD, Eva Hellstrom-Lindberg, MD, Mario Cazzola, MD, Peter J. Campbell, PhD, Jacqueline Boultwood

Blood (2013) 122 (21): 2779.

https://doi.org/10.1182/blood.V122.21.2779.2779

Published: 2013

Journal Articles

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

Blood (2012) 120 (21): 1875.

https://doi.org/10.1182/blood.V120.21.1875.1875

Published: 2012

NARROW

Negative Prognostic Relevance of a Specific 3-Gene Cluster in Myelodysplastic Syndromes during Azacitidine and Lenalidomide Therapy

Comparison of Two Different Therapeutic Regimens with Azacitidine and Lenalidomide (Combined versus Sequential) in Higher-Risk Myelodysplastic Syndromes. Update of Long-Term Results of a Randomized Phase II Multicenter Study

Proteome Analyses and Single-Cell RNA Sequencing Reveal Age-Dependent Re-Wiring of Central Carbon Metabolism in Myeloid-Biased Subsets of Human Hematopoietic Stem Cells

RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Gene Mutations and microRNA Signature in Myelodysplastic Syndromes during Azacitidine and Lenalidomide Therapy

Targeting MDS and AML Stem Cells with AZD-9150 Mediated Inhibition of STAT3

Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations

Molecular and Clinical Characterization of Patients with Myeloid Neoplasms Carrying the 12p Deletion

Combined DNA and Transcriptome Sequencing Reveals Discrete Subtypes of Myelodysplasia

Lineage-Specific Aberrant mRNA Splicing By U2AF1 Mutation Alters Erythroid and Granulomonocytic Differentiation

Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Identification of a Prognostic Gene Expression Signature for AZA Response in MDS and CMML Patients

Efficacy of Dual Inhibition of p38 Mitogen Activated Protein Kinase (MAPK) and Tie-2 Kinase in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Aberration Of SF3B1 Results In Deregulated Splicing Of Key Genes and Pathways In Myelodysplastic Syndromes

Association Between Gene Expression Profiles and Commonly Mutated Genes In The Hematopoietic Stem Cells Of Patients With Myelodysplastic Syndromes

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

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American Society of Hematology

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American Society of Hematology

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