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Andrea Massimiliano Tomirotti, PhD
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Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Maciej Szydlowski, PhD, Filip Garbicz, MD, Ewa Jabłońska, PhD, Patryk Górniak, PhD, Beata Pyrzynska, PhD, Kamil Bojarczuk, PhD, Dorota Komar, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Ciećkiewicz, MD PhD, Grzegorz Rymkiewicz, MDPhD, Magdalena Cybulska, DVM, Małgorzata Statkiewicz, Marta Gajewska, PhD, MIchał Mikula, PhD, Aniela Golas, PhD, Joanna Domagała, MSc, Magdalena Winiarska, Agnieszka Graczyk-Jarzynka, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Joanna Barankiewicz, MD, Bartosz Pula, MDPhD, Michael R Green, PhD, Dominika Nowis, MD PhD, Jakub Golab, Andrea Massimiliano Tomirotti, PhD, Krzysztof Brzózka, PhD, Mariana Pacheco-Blanco, Kristyna Kupcova, Ondrej Havranek, MDPhD, Bjoern Chapuy, MDPhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-134778
Published: 2020
Journal Articles

SEL24/MEN1703 Provides PIM/FLT3 Downstream Pathway Inhibition in Acute Myeloid Leukemia (AML) Blast Cells: Results of the Pharmacodynamics (PD) Assay in the Dose Escalation Part of First-in-Human Diamond Trial

Andrea Massimiliano Tomirotti, PhD, Daniela Bellarosa, Scott R. Solomon, MD, Aziz Nazha, MD, Stephen A Strickland, MD MSCI, Roland P Walter, MDPhD, Farhad Ravandi, MBBS, Krzysztof Brzózka, PhD, Milena Mazan, PhD, Simone Baldini, MD, Massimiliano Salerno, Monica Binaschi, PhD, Dirk Laurent, MD, Andrea Pellacani, PhD MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-136936
Published: 2020
Journal Articles

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Filip Garbicz, MD, Anna Szumera-Ciećkiewicz, MD PhD, Joanna Barankiewicz, MD, Dorota Komar, PhD, Michał Pawlak, PhD, Sonia Dębek, MSc, Aleksandra Matrejek, MSc, Thorsten Stuehmer, PhD, Aleksander Salomon-Perzynski, MD, Agata Malenda, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Andrea Massimiliano Tomirotti, PhD, Ewa Lech-Marańda, MD PhD, Monika Prochorec-Sobieszek, MD PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134979
Published: 2020