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Journal Articles

Outcomes of Patients with Low Variant Allele Fraction JAK2V617F : A 5-Year Retrospective Analysis

Wasithep Limvorapitak, MD, Jeremy Parker, PhD, Lynda Foltz, MD FRCPC, Aly Karsan, MD

Blood (2018) 132 (Supplement 1): 4286.

https://doi.org/10.1182/blood-2018-99-111592

Published: 2018

Journal Articles

Resistance to Lenalidomide in Del(5q) MDS Is Mediated By Inhibition of Drug-Induced Megakaryocytic Differentiation

Sergio Martinez-Høyer, PhD, Angela Mo, Deborah Deng, Jihong Jiang, Rod Docking, MSc, Jenny Li, Simon Chan, Patricia Umlandt, Megan Fuller, Martin Jädersten, Eva Hellström-Lindberg, MD PhD, Uwe Platzbecker, Jeremy Parker, PhD, Aly Karsan, MD

Blood (2018) 132 (Supplement 1): 176.

https://doi.org/10.1182/blood-2018-176

Published: 2018

Journal Articles

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Blood (2018) 132 (Supplement 1): 1322.

https://doi.org/10.1182/blood-2018-99-120120

Published: 2018

Journal Articles

Improved Clinical Assessment of Myeloid Malignancies By Transcriptome Profiling

Rod Docking, MSc, Aly Karsan, MD

Blood (2017) 130 (Supplement 1): 3938.

https://doi.org/10.1182/blood.V130.Suppl_1.3938.3938

Published: 2017

Journal Articles

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Jennifer Grants, PhD, Joanna Wegrzyn, PhD, David Knapp, PhD, Tony Hui, Kieran O'Neill, PhD, Jeremy Parker, PhD, Deborah Deng, Mark Boldin, PhD, Martin Hirst, PhD, Connie J. Eaves, PhD, Aly Karsan, MD

Blood (2017) 130 (Supplement 1): 714.

https://doi.org/10.1182/blood.V130.Suppl_1.714.714

Published: 2017

Journal Articles

Mechanisms of Resistance to Lenalidomide in Del(5q) Myelodysplastic Syndrome Patients

Sergio Martinez-Høyer, PhD, Rod Docking, PhD, Simon Chan, Martin Jadersten, MDPhD, Jeremy Parker, PhD, Aly Karsan, MD

Blood (2015) 126 (23): 5228.

https://doi.org/10.1182/blood.V126.23.5228.5228

Published: 2015

Journal Articles

Clinical Outcomes for Chronic Lymphocytic Leukemia (CLL) Patients with 11q Deletion in British Columbia (BC), Canada: Results of a Population-Based Cohort

Jennifer Goy, MD MSc, Tanya L. Gillan, PhD FCCMG, Huang J.T. Steven, Helene Bruyere, MD FCCMG, Monica Anne Hrynchak, MD FRCPC, Aly Karsan, MD, Khaled Ramadan, MB, MRCP, MRCPath, Adam C. Smith, PhD FCCMG, FACMG, Cynthia L. Toze, MD FRCP(C), Alina S. Gerrie, MD MPH

Blood (2014) 124 (21): 2648.

https://doi.org/10.1182/blood.V124.21.2648.2648

Published: 2014

Journal Articles

Activation of Non-Canonical Immune Signalling Pathways Drives Marrow Failure in a Murine Model of MDS

Rawa Ibrahim, BSc, Joanna Wegrzyn, PhD, Linda Ya-Ting Chang, PhD BSc, Patricia Umlandt, BSc, Jeff Lam, BSc, Megan Fuller, BSc, Aly Karsan, MD

Blood (2014) 124 (21): 3246.

https://doi.org/10.1182/blood.V124.21.3246.3246

Published: 2014

Journal Articles

Loss of MiR-143 and MiR-145 Inhibits Hematopoietic Stem Cell Self-Renewal through Dysregulated TGFβ Signaling

Jeffrey C Lam, BSc, Joanna Wegrzyn-Woltosz, PhD, Rawa Ibrahim, BSc, Kate Slowski, BSc, Patricia Umlandt, BSc, Megan Fuller, BSc, Aly Karsan, MD

Blood (2014) 124 (21): 527.

https://doi.org/10.1182/blood.V124.21.527.527

Published: 2014

Journal Articles

miRNAs, Immune Signaling, and Myelodysplastic Syndromes Pathogenesis

Aly Karsan, MD

Blood (2014) 124 (21): SCI-23.

https://doi.org/10.1182/blood.V124.21.SCI-23.SCI-23

Published: 2014

Journal Articles

The Cost-Effectiveness of Clinical Genomic Tests to Aid CR1 Treatment Decisions in Intermediate-Risk AML

Sonya Cressman, PhD, Aly Karsan, MD, Donna E. Hogge, MD PhD, Emily McPherson, MSC, Stuart Peacock

Blood (2014) 124 (21): 2650.

https://doi.org/10.1182/blood.V124.21.2650.2650

Published: 2014

Journal Articles

Outcome Of Patients With Double-Hit Lymphomas Treated With CODOX-M/IVAC + R Followed By Hematopoietic Stem Cell Transplantation In British Columbia

Blood (2013) 122 (21): 1788.

https://doi.org/10.1182/blood.V122.21.1788.1788

Published: 2013

Journal Articles

Clonal Evolution Predicts Poor Prognosis in Chronic Lymphocytic Leukaemia and Is Possibly a Worse Prognostic Factor Than 17p Deletion: A Population Based Cohort study of FISH Testing in British Columbia, Canada

Krystal Bergin, MBBS, Alina S. Gerrie, MD, FRCPC, Steven J.T. Huang, BMLSc, Khaled M Ramadan, MBBCH, MRCPI, FRCPath, FRCP, FRCPC, Aly Karsan, MD, Monica Anne Hrynchak, MD, FRCP(C), Chinmay B. Dalal, MD, Helene Bruyere, MD, FCCMG, Adam C. Smith, PhD, FCCMG, FACMG, Cynthia L. Toze, MD, MHSc, FRCPC, Tanya L. Gillan, PhD, FCCMG

Blood (2012) 120 (21): 1401.

https://doi.org/10.1182/blood.V120.21.1401.1401

Published: 2012

Journal Articles

Enforced Expression of the Toll/Interleukin-1 Receptor Associated Protein in Murine Marrow Results in MDS-Like Bone Marrow Failure Mediated by Interferon Gamma

Rawa Ibrahim, BSc, Joanna J Wegrzyn Woltosz, Daniel T Starczynowski, PhD, Patricia Umlandt, Aly Karsan, MD

Blood (2012) 120 (21): 555.

https://doi.org/10.1182/blood.V120.21.555.555

Published: 2012

Journal Articles

Comprehensive Assessment of Clinical Outcomes for CLL Patients with Trisomy 12 (+12): Results of a Population-Based Analysis of 822 CLL Patients in British Columbia (BC), Canada

Alina S. Gerrie, MD, FRCPC, MPH, Steven J.T. Huang, BMLSc, Helene Bruyere, MD, FCCMG, Chinmay B. Dalal, MD, Monica Anne Hrynchak, MD, FRCP(C), Aly Karsan, MD, Khaled M Ramadan, MBBCH, MRCPI, FRCPath, FRCP, FRCPC, Adam C. Smith, PhD, FCCMG, FACMG, Tanya L. Gillan, PhD, FCCMG, Cynthia L. Toze, MD, FRCP(C)

Blood (2012) 120 (21): 3897.

https://doi.org/10.1182/blood.V120.21.3897.3897

Published: 2012

Journal Articles

Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML.

Melinda Varney, PhD, Andres Jerez, MD, PhD, Jing Fang, MD/PhD, David Miller, Lyndsey Bolanos, BSc, Aly Karsan, MD, Jaroslaw P. Maciejewski, MD, PhD, Daniel T Starczynowski, PhD

Blood (2012) 120 (21): 2812.

https://doi.org/10.1182/blood.V120.21.2812.2812

Published: 2012

Journal Articles

T Cells of Patients with Myelodysplastic Syndrome Are Frequently Derived From the Malignant Clone

Suzanne Vercauteren, MD, PhD, Daniel T. Starczynowski, PhD, Sandy Sung, Kelly McNeil, Chris Salski, Clara-Lynn Jensen, Helene Bruyere, MD, FCCMG, Wan Lam, Aly Karsan, MD, FRCPC

Blood (2011) 118 (21): 2808.

https://doi.org/10.1182/blood.V118.21.2808.2808

Published: 2011

Journal Articles

Predisposition to Myelodysplastic Syndrome with Deletion 5q Is Associated with TP53 Codon 72 Genotype

Blood (2010) 116 (21): 612.

https://doi.org/10.1182/blood.V116.21.612.612

Published: 2010

Journal Articles

Induction of Micro RNA-143 and 145 In Pre-Treatment CD34+ Cells From Patients with Myelodysplastic Syndrome (MDS) After In Vitro exposure to Lenalidomide Correlates with Clinical Response In Patients Harboring the Del5q Abnormality

Christopher P. Venner, MD, Alan F. List, Thomas J. Nevill, MD, FRCPC, H. Joachim Deeg, Gisela Caceres, Ph.D., Bart Lee Scott, MD, Lubomir Sokol, MD, PhD, Sandy Sung, Aly Karsan, MD, FRCPC

Blood (2010) 116 (21): 123.

https://doi.org/10.1182/blood.V116.21.123.123

Published: 2010

Journal Articles

Genome-Wide Identification of Human Micrornas Located in Leukemia-Associated Genomic Alterations.

Daniel T. Starczynowski, PhD, Ryan Morin, PhD, Andrew McPherson, Martin Hirst, PhD, Marco A. Marra, Ph.D., Wan L Lam, PhD, Aly Karsan, MD

Blood (2009) 114 (22): 1287.

https://doi.org/10.1182/blood.V114.22.1287.1287

Published: 2009

NARROW

Outcomes of Patients with Low Variant Allele Fraction JAK2V617F : A 5-Year Retrospective Analysis

Resistance to Lenalidomide in Del(5q) MDS Is Mediated By Inhibition of Drug-Induced Megakaryocytic Differentiation

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Improved Clinical Assessment of Myeloid Malignancies By Transcriptome Profiling

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Mechanisms of Resistance to Lenalidomide in Del(5q) Myelodysplastic Syndrome Patients

Clinical Outcomes for Chronic Lymphocytic Leukemia (CLL) Patients with 11q Deletion in British Columbia (BC), Canada: Results of a Population-Based Cohort

Activation of Non-Canonical Immune Signalling Pathways Drives Marrow Failure in a Murine Model of MDS

Loss of MiR-143 and MiR-145 Inhibits Hematopoietic Stem Cell Self-Renewal through Dysregulated TGFβ Signaling

miRNAs, Immune Signaling, and Myelodysplastic Syndromes Pathogenesis

The Cost-Effectiveness of Clinical Genomic Tests to Aid CR1 Treatment Decisions in Intermediate-Risk AML

Outcome Of Patients With Double-Hit Lymphomas Treated With CODOX-M/IVAC + R Followed By Hematopoietic Stem Cell Transplantation In British Columbia

Clonal Evolution Predicts Poor Prognosis in Chronic Lymphocytic Leukaemia and Is Possibly a Worse Prognostic Factor Than 17p Deletion: A Population Based Cohort study of FISH Testing in British Columbia, Canada

Enforced Expression of the Toll/Interleukin-1 Receptor Associated Protein in Murine Marrow Results in MDS-Like Bone Marrow Failure Mediated by Interferon Gamma

Comprehensive Assessment of Clinical Outcomes for CLL Patients with Trisomy 12 (+12): Results of a Population-Based Analysis of 822 CLL Patients in British Columbia (BC), Canada

Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML.

T Cells of Patients with Myelodysplastic Syndrome Are Frequently Derived From the Malignant Clone

Predisposition to Myelodysplastic Syndrome with Deletion 5q Is Associated with TP53 Codon 72 Genotype

Induction of Micro RNA-143 and 145 In Pre-Treatment CD34+ Cells From Patients with Myelodysplastic Syndrome (MDS) After In Vitro exposure to Lenalidomide Correlates with Clinical Response In Patients Harboring the Del5q Abnormality

Genome-Wide Identification of Human Micrornas Located in Leukemia-Associated Genomic Alterations.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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