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Alfonso Iorio, MD
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Journal Articles

Creating a Population Model for PK-Tailored Dosing Using Real-World Data from the Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) Platform

Pierre Chelle, PhD, Cindy Yeung, MSc, Santiago Bonanad Boix, MD, Juan Cristobal Morales, MD, Margareth C Ozelo, MD PhD, Juan E. Megias Vericat, PharmD, Alfonso Iorio, MD PhD, Jeffrey Spears, PharmD, Roser Mir, PhD, Andrea N Edginton, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1191.
https://doi.org/10.1182/blood-2018-99-115308
Published: 2018
Journal Articles

Observational Study of Real-World Factor Utilization and Health Outcomes in Patients with Hemophilia in Canada

Haowei Linda Sun, MD FRCPC, Ming Yang, PhD, Man-Chiu Poon, MD, Adrienne Lee, MD, Katherine Sue Robinson, MD, Michelle Sholzberg, MDM, MSc, FRCPC, John K. Wu, MBBS, FRCPC, MS, Alfonso Iorio, MD PhD, Victor S. Blanchette, FRCP, Robert J Klaassen, MD FRCPC, Shannon Jackson, MD FRCPC
Journal: Blood
Blood (2018) 132 (Supplement 1): 4813.
https://doi.org/10.1182/blood-2018-99-113858
Published: 2018
Journal Articles

Prospective Study of the Immunological Mechanisms of Immune Tolerance Induction in Severe Haemophilia a Patients with Inhibitors: Preliminary Analysis of a Multi-Center Longitudinal Study

Davide Matino, MD MSc, Giancarlo Castaman, Giovanni Di Minno, Paola Giordano, MD, Maria Elisa Mancuso, Emanuela Marchesini, Flora Peyvandi, MD PhD, Elena Santagostino, Cristina Santoro, MD PhD, Michele Schiavulli, Antonella De Luca, PhD, Marco Gargaro, Paolo Puccetti, MD, Francesca Fallarino, PhD, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3781.
https://doi.org/10.1182/blood-2018-99-119568
Published: 2018
Journal Articles

Population Pharmacokinetics Profiling to Tailor Prophylaxis in Hemophilia a Patients: A Pilot Feasibility Study

Michaela Stemberger, Felix Kallenbach, Elisabeth Schmit, Alanna McEneny-King, Andrea N Edginton, PhD, Alfonso Iorio, MD PhD, Karin Kurnik
Journal: Blood
Blood (2017) 130 (Supplement 1): 2404.
https://doi.org/10.1182/blood.V130.Suppl_1.2404.2404
Published: 2017
Journal Articles

Comparative Assessment of the Performance of Pharmacokinetic Tools for Prophylactic Dosing of Antihemophilic Factor Recombinant Plasma/Albumin-Free Method (rAHF-PFM) Concentrate in Patients with Hemophilia A

Phillip Staibano, BSc, MSc, Alanna McEneny-King, MSc, PhDc), Massimo Morfini, MD, Gary Foster, PhD, Nicholas Hobson, Tamara Navarro-Ruan, MSc, Andrea N Edginton, PhD, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4934.
https://doi.org/10.1182/blood.V130.Suppl_1.4934.4934
Published: 2017
Journal Articles

Sexual Health in Patients with Hemophilia; The Insights from the Patient Reported Outcomes, Burdens and Experiences (PROBE) Study

Chatree Chai-Adisaksopha, MD, Mark Skinner, Randall Curtis, MBA, Neil Frick, Michael B. Nichol, PhD, Declan Noone, Brian O'Mahony, David Page, Jeffrey Stonebraker, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2141.
https://doi.org/10.1182/blood.V130.Suppl_1.2141.2141
Published: 2017
Journal Articles

An Individual Participant Data Meta-Analysis of 13 Randomized Trials to Evaluate the Impact of Prophylactic Use of Heparin in Oncological Patients

Holger Schünemann, MD, Matthew Ventresca, MSc, Mark Crowther, MD, Marcello Di Nisio, MD, Matthias Briel, PhD MSc, Qi Zhou, PhD, Simon Noble, Fergus Macbeth, Gareth Griffiths, David A Garcia, MD, Gary H. Lyman, MD MPH, FRCP, Alfonso Iorio, MD PhD, Lawrence Mbuagbaw, Ignacio Neumann, Nick Van Es, Jan Brozek, Gordon Guyatt, Michael B. Streiff, Melissa Brouwers, Tejan Baldeh, Maura Marcucci, Ivan Florez, Ziad Solh, Walter Ageno, Suzanne Bleker, George Bozas, Harry Büller, Clara Klerk, Bernard Lebeau, Ramon Lecumberri, Robert D. McBane, MD, Kostandinos Sideras, Anthony Maraveyas, Uwe Pelzer, Charles Loprinzi, Patrick Bossuyt, Lara Kahale, Elie A Akl, Gilbert Zulian
Journal: Blood
Blood (2017) 130 (Supplement 1): 626.
https://doi.org/10.1182/blood.V130.Suppl_1.626.626
Published: 2017
Journal Articles

The Khorana Score for the Prediction of Venous Thromboembolism in Patients with Solid Cancer: An Individual Patient Data Meta-Analysis

Nick Van Es, Matthew Ventresca, MSc, Qi Zhou, PhD, Simon Noble, Mark Crowther, MD, Matthias Briel, PhD MSc, David A Garcia, MD, Gary H. Lyman, MD MPH, FRCP, Fergus Macbeth, Gareth Griffiths, Alfonso Iorio, MD PhD, Lawrence Mbuagbaw, Ignacio Neumann, Jan Brozek, Gordon Guyatt, Michael B. Streiff, Ivan Florez, Ziad Solh, Walter Ageno, Maura Marcucci, George Bozas, Anthony Maraveyas, Bernard Lebeau, Ramon Lecumberri, Kostandinos Sideras, Charles Loprinzi, Robert D. McBane, MD, Suzanne Bleker, Uwe Pelzer, Elie A Akl, Patrick Bossuyt, Lara Kahale, Harry Büller, Holger Schünemann, MD, Gilbert Zulian
Journal: Blood
Blood (2017) 130 (Supplement 1): 627.
https://doi.org/10.1182/blood.V130.Suppl_1.627.627
Published: 2017
Journal Articles

Evaluation of Plasma-Derived FVII Efficacy for the Treatment of Bleeding in a Murine Model of Hemophilia a

Davide Matino, MD, Antonella De Luca, PhD, Paolo Puccetti, MD, Francesca Fallarino, PhD, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1070.
https://doi.org/10.1182/blood.V130.Suppl_1.1070.1070
Published: 2017
Journal Articles

Psychometric Properties of the Patient Reported Outcomes Burdens and Experiences (PROBE) Questionnaire

Chatree Chai-Adisaksopha, MD, Mark Skinner, Randall Curtis, MBA, Neil Frick, Michael B. Nichol, PhD, Declan Noone, Brian O'Mahony, David Page, Jeffrey Stonebraker, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5645.
https://doi.org/10.1182/blood.V130.Suppl_1.5645.5645
Published: 2017
Journal Articles

Burden of Comorbid Diseases in Patients with Hemophilia: The Cross-Sectional Analysis of the Patient Reported Outcomes, Burden and Experiences (PROBE) Study

Mark Skinner, Chatree Chai-Adisaksopha, MD, Randall Curtis, MBA, Neil Frick, Declan Noone, Brian O'Mahony, David Page, Jeffrey Stonebraker, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3411.
https://doi.org/10.1182/blood.V130.Suppl_1.3411.3411
Published: 2017
Journal Articles

Clinical and Biological Determinants of Bleeding Manifestation in Congenital Factor XI Deficiency; A Systematic Review

Milana Drakulic, Chatree Chai-Adisaksopha, MD, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1407.
https://doi.org/10.1182/blood.V128.22.1407.1407
Published: 2016
Journal Articles

Perioperative Management of Von Willebrand Disease, a Systematic Review and Meta-Analysis

Chatree Chai-Adisaksopha, MD, Davide Matino, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1408.
https://doi.org/10.1182/blood.V128.22.1408.1408
Published: 2016
Journal Articles

The Effect of Platelet Transfusion on Death in the Intensive Care Unit

Donald M. Arnold, MD, Shuoyan Ning, MD, Rebecca Barty, MLT, CTRC, Yang Liu, MMath, Richard Cook, M. Math, PhD, Bram Rochberg, MD MSc, Alfonso Iorio, MD PhD, Andrew W. Shih, MD BSc, Nancy M Heddle, MSc
Journal: Blood
Blood (2016) 128 (22): 3850.
https://doi.org/10.1182/blood.V128.22.3850.3850
Published: 2016
Journal Articles

Interim Canadian Data from a Prospective, Observational Study of Routine Clinical Use of a Von Willebrand Factor Concentrate (Wilate®)

Lidia Cosentino, PhD, Paula D. James, MD, Michelle Sholzberg, MDM, MSc, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2593.
https://doi.org/10.1182/blood.V128.22.2593.2593
Published: 2016
Journal Articles

Installing FVIII-Specific Tolerance in Hemophilia Via Engagement of the Aryl Hydrocarbon Receptor By Tryptophan Derivatives

Davide Matino, Marco Gargaro, Giulia Scalisi, Antonella Turco, Francisco Javier Quintana, Paolo Puccetti, Alfonso Iorio, MD PhD, Francesca Fallarino
Journal: Blood
Blood (2016) 128 (22): 2563.
https://doi.org/10.1182/blood.V128.22.2563.2563
Published: 2016
Journal Articles

Warfarin Resumption after Intracranial Hemorrhage: A Systematic Review and Meta-Analysis

Chatree Chai-Adisaksopha, MD, Christopher M Hillis, MD FRCPC, Daniel M. Witt, PharmD, FCCP, BCPS, Sam Schulman, MD PhD FRCPC, Mark Crowther, MD, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3821.
https://doi.org/10.1182/blood.V128.22.3821.3821
Published: 2016
Journal Articles

Perioperative Management for Congenital Factor XI Deficiency; A Systematic Review

Chatree Chai-Adisaksopha, MD, Thanawat Rattanathammethee, MD, Milana Drakulic, Davide Matino, Alfonso Iorio, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3796.
https://doi.org/10.1182/blood.V128.22.3796.3796
Published: 2016
Journal Articles

Test-Retest Reliability Analysis of the Patient Reported Outcomes Burdens and Experiences (PROBE)

Chatree Chai-Adisaksopha, MD, Alfonso Iorio, MD PhD, Randall Curtis, Neil Frick, MS, Michael Nichol, Declan Noone, Brian O'Mahony, David Page, Jeffrey Stonebraker, Mark Skinner
Journal: Blood
Blood (2016) 128 (22): 5964.
https://doi.org/10.1182/blood.V128.22.5964.5964
Published: 2016
Journal Articles

Switching to Warfarin after 6-Month Completion of Anticoagulant Treatment for Cancer-Associated Thrombosis

Chatree Chai-Adisaksopha, MD, Alfonso Iorio, MD PhD, Mark A. Crowther, MD MSc, FRCPC, Javier de Miguel, MD, Estuardo Salgado, MD, Marija Zdraveska, MD, Manuel Monreal, MD PhD
Journal: Blood
Blood (2015) 126 (23): 430.
https://doi.org/10.1182/blood.V126.23.430.430
Published: 2015