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Journal Articles

Immunomodulatory Effects of Pevonedistat, a NEDD8-Activating Enzyme (NAE) Inhibitor, in Chronic Lymphocytic Leukemia (CLL)

Scott R Best, BS, Adam Kittai, MD, Taylor Rowland, BS, Nur Bruss, BS, Stephen E Spurgeon, MD, Allison Berger, PhD, Amy Moran, PhD, Alexey V Danilov, MD PhD

Blood (2018) 132 (Supplement 1): 2946.

https://doi.org/10.1182/blood-2018-99-115086

Published: 2018

Journal Articles

Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib Alone or in Combination with Idelalisib or Entospletinib in Patients with Previously Treated Chronic Lymphocytic Leukemia

Alexey V Danilov, MD PhD, Charles Herbaux, MD, Martin J.S. Dyer, MA, DPhil, FRCP, FRCPath, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, Simon Rule, MD, Ebenezer A Kio, MD, Xi Huang, PhD, Siddhartha Mitra, MD PhD, Lionel Karlin, MD, Christopher Fegan, MD

Blood (2018) 132 (Supplement 1): 3135.

https://doi.org/10.1182/blood-2018-99-113111

Published: 2018

Journal Articles

Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination with Entospletinib in Patients with B-Cell Lymphoma

Gilles Salles, MD PhD, Martin J.S. Dyer, MA, DPhil, FRCP, FRCPath, Daniel James Hodson, MD PhD, Krimo Bouabdallah, MD, Loic Ysebaert, MD PhD, Guillaume Cartron, Andrew John Davies, PhD, Alexey V Danilov, MD PhD, Christopher Fegan, MD, Ebenezer A Kio, MD, Xi Huang, PhD, Siddhartha Mitra, MD PhD, Simon Rule, MD, Franck Morschhauser, MD

Blood (2018) 132 (Supplement 1): 5344.

https://doi.org/10.1182/blood-2018-99-113115

Published: 2018

Journal Articles

Dual Inhibition of Bruton's Tyrosine Kinase and BCL2: A Promising Therapeutic Strategy for Myeloid and Lymphoid Leukemias

Christopher A. Eide, Stephen E Kurtz, PhD, Andy Kaempf, Cristina E. Tognon, PhD, Motomi Mori, PhD, Max J. Gordon, MD, Jeffrey W. Tyner, PhD, Alexey V Danilov, MD PhD, Brian J. Druker, MD

Blood (2018) 132 (Supplement 1): 214.

https://doi.org/10.1182/blood-2018-99-117468

Published: 2018

Journal Articles

Intensive Induction Regimens after Deferring Initial Therapy Are Not Associated with Improved Progression-Free or Overall Survival in Patients with Mantle Cell Lymphoma (MCL)

Blood (2018) 132 (Supplement 1): 4153.

https://doi.org/10.1182/blood-2018-99-117547

Published: 2018

Journal Articles

Outcomes of Follicular Lymphoma Patients Treated with Frontline Bendamustine and Rituximab: Impact of Histologic Grade and Early Progression on Overall Survival

Allison M. Winter, MD, Loretta J. Nastoupil, MD, Melody R. Becnel, MD, James R. Cerhan, MD PhD, Thomas M. Habermann, MD, Brian K. Link, MD, Matthew J. Maurer, MS, Bita Fakhri, MD MPH, Prathima Reddy, MD, Stephen D. Smith, MD, Dhruvika Mukhija, MD, Deepa Jagadeesh, MD MPH, Amrita Desai, MD, Juan Pablo Alderuccio, MD, Izidore S. Lossos, MD, Pooja Mehra, MD, Craig A. Portell, MD, Christopher R. D'Angelo, MD, Vaishalee P. Kenkre, MD, Max L. Goldman, MD, Oscar Calzada, BS, Jonathon B. Cohen, MD MS, Mohammad Junaid Hussain, MD, Nilanjan Ghosh, MD PhD, Yang Liu, MD, Stefan Klaus Barta, MD MRCP, MS, Paolo F Caimi, MD, Adam Kittai, MD, Alexey V Danilov, MD PhD, Timothy Tiutan, MD, Peter Martin, FRCPC, MD MS, Nathalie Danielson, MSN, RN, ACNP-BC, Manali Kamdar, MD, Abhigna Kodali, MD, Andrew M. Evens, DO, MSc, Brad S Kahl, MD, Brian T. Hill, MD PhD

Blood (2018) 132 (Supplement 1): 4146.

https://doi.org/10.1182/blood-2018-99-118530

Published: 2018

Journal Articles

Impact of Individual Comorbidities on Treatment Outcomes in Chronic Lymphocytic Leukemia

Max J. Gordon, MD, Michael C Churnetski, BS, Hamood Alqahtani, MBBS, Xavier Issac Rivera, BS, Adam Kittai, MD, Nur Bruss, BS, Sheila Hoff, BSN, Michael Y. Choi, MD, Jonathon B. Cohen, MD MS, Daniel Persky, MD, Byung Park, PhD, Alexey V Danilov, MD PhD

Blood (2018) 132 (Supplement 1): 4848.

https://doi.org/10.1182/blood-2018-99-113917

Published: 2018

Journal Articles

CG'806, a First-in-Class Pan-FLT3/Pan-BTK Inhibitor, Exhibits Broader and Greater Potency Than Ibrutinib Against Primary and Cultured Malignant B Cells

Hongying Zhang, MD, PhD, Andrea Local, PhD, Khalid Benbatoul, BS, Peter Folger, BS, Susan Sheng, PhD, Taryn McLaughlin, MS, Alexey V Danilov, MD PhD, Stephen E Kurtz, PhD, Jeffrey W. Tyner, PhD, Stephen Howell, MD, William G Rice, PhD

Blood (2018) 132 (Supplement 1): 3503.

https://doi.org/10.1182/blood-2018-99-117285

Published: 2018

Journal Articles

TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in CLL Cells

Scott R Best, BS, Taylor Rowland, BS, Cody Paiva, BS, Nur Bruss, BS, Stephen E Spurgeon, MD, Allison Berger, PhD, Alexey V Danilov, MD PhD

Blood (2018) 132 (Supplement 1): 1867.

https://doi.org/10.1182/blood-2018-99-114964

Published: 2018

Journal Articles

Chronic Lymphocytic Leukemia (CLL) Transformed into Hodgkin Lymphoma (HL): Clinical Characteristics and Outcomes from a Large Multi-Center Collaboration

Blood (2018) 132 (Supplement 1): 1648.

https://doi.org/10.1182/blood-2018-99-113173

Published: 2018

Journal Articles

Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

Adam Kittai, MD, Scott R Best, BS, Taylor Rowland, BS, Nur Bruss, BS, Craig Okada, MD PhD, Alexey V Danilov, MD PhD

Blood (2018) 132 (Supplement 1): 1667.

https://doi.org/10.1182/blood-2018-99-113179

Published: 2018

Journal Articles

SYK Inhibition Disrupts the Cross-Talk Between B-Cell Activation Factor (BAFF) and B-Cell Receptor (BCR) and Thereby Antagonizes Mcl-1 in Chronic Lymphocytic Leukemia (CLL) B-Cells

Cody Paiva, BS, Taylor Rowland, Olga Danilova, Bhargava Sreekantham, Stephen E Spurgeon, MD, Alexey V Danilov, MD PhD

Blood (2016) 128 (22): 303.

https://doi.org/10.1182/blood.V128.22.303.303

Published: 2016

Journal Articles

Voruciclib Sensitizes High Risk Diffuse Large B Cell Lymphoma to BCL2 Inhibition Mediated Cell Death and Tumor Regression

Joyoti Dey, PhD MPH, William Kerwin, PhD, Joseph Casalini, BS, Angela Merrell, BS, Marc Grenley, BS, Sally Ditzler, BS, Chantel Dixon, BS, Connor Burns, BS, Alexey V Danilov, MD PhD, Richard Klinghoffer, PhD

Blood (2016) 128 (22): 4167.

https://doi.org/10.1182/blood.V128.22.4167.4167

Published: 2016

Journal Articles

Selective Targeting Cyclin-Dependent Kinase-9 (CDK9) Downmodulates c-MYC and Induces Apoptosis in Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Taylor Rowland, Cody Paiva, BS, Joelle Rowley, Andy Chen, MD PhD, Lisa Drew, PhD, Peter Hurlin, Bill H. Chang, MD PhD, Alexey V Danilov, MD PhD

Blood (2016) 128 (22): 289.

https://doi.org/10.1182/blood.V128.22.289.289

Published: 2016

Journal Articles

Risk Stratification of Untreated Mantle Cell Lymphoma Patients Using MIPI, Ki67 Proliferative Index and Cytogenetics

Ashley D. Staton, MD, Irl Brian Greenwell, MD, Jeffrey M Switchenko, Joseph Maly, MD, Kristie Blum, MD, Natalie S. Grover, MD, Stephanie Mathews, Steven I. Park, MD, Max J. Gordon, MD, Alexey V Danilov, MD PhD, Narendranath Epperla, MD, Timothy S Fenkse, MD MS, Mehdi Hamadani, MD, Christopher Flowers, MD MS, Jonathon B. Cohen, MD

Blood (2016) 128 (22): 1785.

https://doi.org/10.1182/blood.V128.22.1785.1785

Published: 2016

Journal Articles

Prognostic Markers in Cardiac Non-Hodgkin Lymphoma: A Retrospective Review

Max J Gordon, MD, Alexey V. Danilov, MD PhD

Blood (2015) 126 (23): 5007.

https://doi.org/10.1182/blood.V126.23.5007.5007

Published: 2015

Journal Articles

Pevonedistat Sensitizes Diffuse Large B-Cell Lymphoma Cells to Death Receptor Ligand-Mediated Apoptosis

Cody Paiva, BS, Claire Godbersen, Christopher George Danes, PhD, Stephen E Spurgeon, MD, Allison Berger, Alexey V Danilov, MD PhD

Blood (2015) 126 (23): 3994.

https://doi.org/10.1182/blood.V126.23.3994.3994

Published: 2015

Journal Articles

Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells

Cody Paiva, BS, Claire Godbersen, Stephen E Spurgeon, MD, Sreesha Srinivasa, Jennifer R Brown, MD PhD, Alexey V Danilov, MD PhD

Blood (2015) 126 (23): 1752.

https://doi.org/10.1182/blood.V126.23.1752.1752

Published: 2015

Journal Articles

Feasibility of Interim PET-Adapted Therapy in HIV-Positive Patients with Advanced Hodgkin Lymphoma (HL): Sub-Analysis of SWOG S0816 Phase 2 Trial

Alexey V Danilov, MD PhD, Hongli Li, PhD, Oliver W. Press, Ilan Shapira, MD, Lode J. Swinnen, MBChB, Ariela Noy, MD, Erin Reid, MD, Sonali M. Smith, MD, Jonathan W. Friedberg, MD MMSc

Blood (2015) 126 (23): 1498.

https://doi.org/10.1182/blood.V126.23.1498.1498

Published: 2015

Journal Articles

microRNA-21 Is Differentially Expressed in the Lymphoid Tissue and Modulated By Stromal Signaling in Chronic Lymphocytic Leukemia

Cody Paiva, Olga Danilova, MD PhD, Ahsan S Kamal, Prabhjot Kaur, MD, Alexey V. Danilov, MD PhD

Blood (2014) 124 (21): 1975.

https://doi.org/10.1182/blood.V124.21.1975.1975

Published: 2014

NARROW

Immunomodulatory Effects of Pevonedistat, a NEDD8-Activating Enzyme (NAE) Inhibitor, in Chronic Lymphocytic Leukemia (CLL)

Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib Alone or in Combination with Idelalisib or Entospletinib in Patients with Previously Treated Chronic Lymphocytic Leukemia

Updated Preliminary Results of a Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination with Entospletinib in Patients with B-Cell Lymphoma

Dual Inhibition of Bruton's Tyrosine Kinase and BCL2: A Promising Therapeutic Strategy for Myeloid and Lymphoid Leukemias

Intensive Induction Regimens after Deferring Initial Therapy Are Not Associated with Improved Progression-Free or Overall Survival in Patients with Mantle Cell Lymphoma (MCL)

Outcomes of Follicular Lymphoma Patients Treated with Frontline Bendamustine and Rituximab: Impact of Histologic Grade and Early Progression on Overall Survival

Impact of Individual Comorbidities on Treatment Outcomes in Chronic Lymphocytic Leukemia

CG'806, a First-in-Class Pan-FLT3/Pan-BTK Inhibitor, Exhibits Broader and Greater Potency Than Ibrutinib Against Primary and Cultured Malignant B Cells

TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in CLL Cells

Chronic Lymphocytic Leukemia (CLL) Transformed into Hodgkin Lymphoma (HL): Clinical Characteristics and Outcomes from a Large Multi-Center Collaboration

Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

SYK Inhibition Disrupts the Cross-Talk Between B-Cell Activation Factor (BAFF) and B-Cell Receptor (BCR) and Thereby Antagonizes Mcl-1 in Chronic Lymphocytic Leukemia (CLL) B-Cells

Voruciclib Sensitizes High Risk Diffuse Large B Cell Lymphoma to BCL2 Inhibition Mediated Cell Death and Tumor Regression

Selective Targeting Cyclin-Dependent Kinase-9 (CDK9) Downmodulates c-MYC and Induces Apoptosis in Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Risk Stratification of Untreated Mantle Cell Lymphoma Patients Using MIPI, Ki67 Proliferative Index and Cytogenetics

Prognostic Markers in Cardiac Non-Hodgkin Lymphoma: A Retrospective Review

Pevonedistat Sensitizes Diffuse Large B-Cell Lymphoma Cells to Death Receptor Ligand-Mediated Apoptosis

Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells

Feasibility of Interim PET-Adapted Therapy in HIV-Positive Patients with Advanced Hodgkin Lymphoma (HL): Sub-Analysis of SWOG S0816 Phase 2 Trial

microRNA-21 Is Differentially Expressed in the Lymphoid Tissue and Modulated By Stromal Signaling in Chronic Lymphocytic Leukemia

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American Society of Hematology

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American Society of Hematology

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