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Alessandro Zarpellon
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Journal Articles

Pathogen Reduced Cryoprecipitated Fibrinogen Complex (IFC) and Cryoprecipitated AHF Contain Von Willebrand Factor with Comparable Binding to Collagen and Support Shear-Induced Platelet Thrombus Formation

Subramanian Yegneswaran, Alessandro Zarpellon, Jennifer N Orje, Michelle Gatmaitan, Nina Mufti, Laurence Corash, Zaverio M Ruggeri
Journal: Blood
Blood (2023) 142 (Supplement 1): 4039.
https://doi.org/10.1182/blood-2023-187124
Published: 2023
Journal Articles

Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets

Alessandro Zarpellon, PhD, Taisuke Kanaji, MD, Sachiko Kanaji, MD PhD, Yosuke Morodomi, MD PhD, Zaverio M. Ruggeri, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 451.
https://doi.org/10.1182/blood.V130.Suppl_1.451.451
Published: 2017
Journal Articles

Extracellular Tyrosyl-tRNA Synthetase Is a Potent Stimulator of Thrombocytopoiesis

Sachiko Kanaji, MD PhD, Taisuke Kanaji, MD PhD, My-Nuong Vo, PhD, Alessandro Zarpellon, PhD, Ryan Shapiro, Rajesh Belani, MD, Minh-Ha Do, PhD, Xiang-Lei Yang, PhD, Zaverio M. Ruggeri, MD, Paul Schimmel, PhD
Journal: Blood
Blood (2016) 128 (22): 1476.
https://doi.org/10.1182/blood.V128.22.1476.1476
Published: 2016
Journal Articles

Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis

Sachiko Kanaji, MD PhD, Jennifer N Orje, Yuichi Kamikubo, PhD, Taisuke Kanaji, MD PhD, Jeremy Mattson, Alessandro Zarpellon, PhD, Scot A. Fahs, Rashmi Sood, PhD, Sandra L Haberichter, PhD, Zaverio M. Ruggeri, MD, Robert R Montgomery, MD
Journal: Blood
Blood (2016) 128 (22): 558.
https://doi.org/10.1182/blood.V128.22.558.558
Published: 2016
Journal Articles

Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe

Xiaohong Xu, MD, Christopher M. Spring, MSc, Lining Ju, PhD, Yiming Wang, MD, Adili Reheman, MD, Hong Yang, MD, Joseph Wuxun Jin, PhD, Xi Lei, MSc, Yan Yang, MD PhD, Emily C. Reddy, PhD, Yunfeng Chen, PhD, Pingguo Chen, MD PhD, Guangheng Zhu, MD, Patrizia Marchese, PhD, Alessandro Zarpellon, PhD, Hailong Zhang, PhD, YiMin She, PhD, Terry Cyr, PhD, Cheng Zhu, PhD, John Freedman, MD, Patrick Tso, PhD, Sean Davidson, PhD, Zaverio M. Ruggeri, MD, Heyu Ni, MD PhD
Journal: Blood
Blood (2014) 124 (21): 92.
https://doi.org/10.1182/blood.V124.21.92.92
Published: 2014
Journal Articles

Platelet Aggregation and Fibrin Deposition: The Yin and Yang of Thrombin Activity Regulation By Platelet Glycoprotein Ibα

Alessandro Zarpellon, PhD, Patrizia Marchese, PhD, Antonella Zampolli, Dr. Biol., Grazia Loredana Mendolicchio, MD PhD, Zaverio M. Ruggeri, MD
Journal: Blood
Blood (2014) 124 (21): 114.
https://doi.org/10.1182/blood.V124.21.114.114
Published: 2014
Journal Articles

GPIbα As a Selective Bidirectional Modulator Of α-Thrombin Prothrombotic Functions Influencing Fibrin Deposition and PAR-Dependent Platelet Activation

Alessandro Zarpellon, PhD, Antonella Zampolli, PhD, Patrizia Marchese, PhD, James R. Roberts, Grazia Loredana Mendolicchio, MD, PhD, Zaverio M Ruggeri, MD
Journal: Blood
Blood (2013) 122 (21): 32.
https://doi.org/10.1182/blood.V122.21.32.32
Published: 2013
Journal Articles

Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane

Lea Scheppke, Eric A. Murphy, Alessandro Zarpellon, Jennifer J. Hofmann, Alona Merkulova, David J. Shields, Sara M. Weis, Tatiana V. Byzova, Zaverio M. Ruggeri, M. Luisa Iruela-Arispe, David A. Cheresh
Journal: Blood
Blood (2012) 119 (9): 2149–2158.
https://doi.org/10.1182/blood-2011-04-348706
Published: 2012
Includes: Supplemental data
Journal Articles

Structural and Functional Evidence on the Role of Sulfated Tyrosine Residues In Glycoprotein Ib Binding to α-Thrombin Exosites

Alessandro Zarpellon, PhD, Reha Celikel, Richard McClintock, James R. Roberts, G. Loredana Mendolicchio, MD, PhD, Hua Jing, PhD, Kottayil I Varughese, PhD, Zaverio M. Ruggeri, MD
Journal: Blood
Blood (2010) 116 (21): 326.
https://doi.org/10.1182/blood.V116.21.326.326
Published: 2010
Journal Articles

Mechanism and Functional Consequences of Thrombin Binding to Glycoprotein Ib.

Alessandro Zarpellon, PhD, Antonella Zampolli, PhD, Loredana Mendolicchio, MD, PhD, James R Roberts, Zaverio M. Ruggeri, MD
Journal: Blood
Blood (2009) 114 (22): 474.
https://doi.org/10.1182/blood.V114.22.474.474
Published: 2009
Journal Articles

Mechanism of α-Thrombin Binding to Platelet Glycoprotein Ibα

Alessandro Zarpellon, PhD, Richard A. McClintock, James R. Roberts, Zaverio M. Ruggeri, MD
Journal: Blood
Blood (2008) 112 (11): 2867.
https://doi.org/10.1182/blood.V112.11.2867.2867
Published: 2008