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Alessandra Trojani, PhD
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Journal Articles

Cell Surface Proteins of B Cells and Plasmacells Are Differently Expressed in Waldenström's Macroglobulinemia (WM) Patients Vs. Subjects with Monoclonal Gammopathy of Uncertain Significance (IgMMGUS) Vs. Healthy Donors

Alessandra Trojani, PhD, Barbara Di Camillo, Luca Emanuele Bossi, Alessandra Tedeschi, MD, Annamaria Frustaci, Alessandro Beghini, Marco Montillo, Roberto Cairoli, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41.
https://doi.org/10.1182/blood-2020-134569
Published: 2020
Journal Articles

Nilotinib Deregulates Cell Cycle Checkpoints, ABC Transporters Genes and JAK-STAT Signaling Pathway of CD34+/Lin- Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients after 12 Months of Treatment

Alessandra Trojani, PhD, Ester Pungolino, Giuseppe Rossi, MD, Mariella D'adda, MD, Milena Lodola, PhD, Alessandra Dal Molin, PhD, Giacomo Baruzzo, PhD, Alessandra Perego, MD, Mauro Turrini, MD, Chiara Elena, MD, Lorenza Maria Borin, MDcal doctor, Alessandra Iurlo, Simona Malato, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Pierangelo Spedini, MD, Salvatore Artale, MD, Michela Anghilieri, MD, Carraro Maria Cristina, MD, Cristina Bucelli, MD, Gabriella De Canal, PhD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5122.
https://doi.org/10.1182/blood-2018-99-112188
Published: 2018
Journal Articles

Combining Imatinib-Following-Nilotinib Treatment in First Line Therapy for Chronic Phase Chronic Myeloid Leukemia. Update from the PhilosoPhi34 Study at 24 Months of Follow-up

Maria Luisa Pioltelli, MD, Ester Pungolino, Mariella D'adda, MD, Chiara Elena, MD, Lorenza Maria Borin, MDcal doctor, Alessandra Perego, MD, Alessandra Iurlo, Alessandra Trojani, PhD, Mauro Turrini, MD, Marianna Caramella, MD, Pierangelo Spedini, MD, Simona Malato, MD, Francesco Spina, MD, Salvatore Artale, MD, Mariacristina Carraro, Nicola Orofino, MD, Michela Anghilieri, MD, Mirko Farina, MD, Maria Luisa Latargia, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5435.
https://doi.org/10.1182/blood-2018-99-113496
Published: 2018
Journal Articles

Jak-2 and Nfkbia G ene Expression Play a Strategic Role in Chronic Myeloid Leukemia (CML) Molecular Response during Early Nilotinib Treatment: The PhilosoPhi34 Data

Ester Pungolino, Mariella D'adda, MD, Alessandra Trojani, PhD, Alessandra Perego, MD, Chiara Elena, MD, Alessandra Iurlo, Simona Malato, MD, Mauro Turrini, MD, Gabriella De Canal, PhD, Lorenza Borin, MD, Milena Lodola, PhD, Marianna Caramella, MD, Salvatore Artale, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Michela Anghilieri, MD, Pierangelo Spedini, MD, Mariacristina Carraro, Barbara Di Camillo, Doriana Gramegna, MD, Maria Luisa Pioltelli, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5118.
https://doi.org/10.1182/blood-2018-99-113273
Published: 2018
Journal Articles

The REL-Protocol PhilosoPhi34 - an Open Label, Single Arm, Phase II Study of Nilotinib 300 Mg BID in Newly Diagnosed Chronic Phase Chronic Myeloid Leukaemia (CML) Patients - Confirms Early Clearance of Bone Marrow CD34+/Lin-Ph+ Cells

Ester Pungolino, MD, Gabriella De Canal, Mariella D'adda, MD, Alessandra Perego, MD, Mauro Turrini, MD, Ester Maria Orlandi, MD, Alessandra Trojani, PhD, Lorenza Borin, MD, Alessandra Iurlo, MD, Maria Luisa Latargia, MD, Simona Malato, MD, Maria Cristina Carraro, MD, Stefania Brusorio, Chiara Elena, MD, Francesco Spina, MD, Milena Lodola, Salvatore Artale, MD, Michela Anghilieri, MD, Cristina Bucelli, MD, Maria Luisa Pioltelli, MD, Silvia Cantoni, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2016) 128 (22): 3080.
https://doi.org/10.1182/blood.V128.22.3080.3080
Published: 2016
Journal Articles

GEP Analyses of Bone Marrow CD34+/Lin- Cells of Chronic Phase CML Patients at Diagnosis Identified Different Sets of Genes Associated to the Molecular Response after 3 and 6 Months of First-Line Nilotinib Treatment

Alessandra Trojani, PhD, Ester Pungolino, MD, Milena Lodola, Barbara Di Camillo, Mariella D'Adda, MD, Alessandra Perego, MD, Mauro Turrini, MD, Chiara Elena, MD, Alessandra Iurlo, MD PhD, Cristina Buccelli, Simona Malato, MD, Francesco Spina, MD, Maria Luisa Latargia, Francesco Lanza, Sergio Pauli, MD, Michela Anghilieri, MD, Maria Cristina Carraro, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2015) 126 (23): 3645.
https://doi.org/10.1182/blood.V126.23.3645.3645
Published: 2015
Journal Articles

The Clonal Architecture of CXCR4mutations in Waldenstrom's Macroglobulinemia Shows Highly Variable Subclonal Distribution, and Multiple Mutations within Individual Patients Indicative of Targeted Genomic Instability

Lian Xu, Zachary Hunter, PhD, Nicholas Tsakmaklis, Yang Cao, MD, Guang Yang, PhD, Jie Chen, PhD, Xia Liu, MD, Sandra Kanan, NP, RN, MSN, Jorge J Castillo, MD, Yu-Tzu Tai, PhD, James L. Zehnder, MD, Jennifer R. Brown, MD PhD, Ruben D. Carrasco, MD PhD, Ranjana H Advani, MD, Kimon V. Argyropoulos, MD, M. Lia Palomba, MD, Enrica Morra, MD, Alessandra Trojani, PhD, Antonino Greco, MD, Alessandra Tedeschi, MD, Marzia Varettoni, MD, Luca Arcaini, Nikhil C. Munshi, MD, Kenneth C Anderson, MD, Steven P Treon, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1486.
https://doi.org/10.1182/blood.V126.23.1486.1486
Published: 2015
Journal Articles

REL-Protocol PhilosoPhi34: An Open Label, Single Arm, Phase II Study of Nilotinib 300 Mg BID in Newly Diagnosed Chronic Phase Chronic Myeloid Leukaemia Patients, to Study the Disappearance of CD34+/Lin-Ph+ Cells from Bone Marrow during Treatment. Preliminary Data

Ester Pungolino, MD, Giuseppe Rossi, MD, Maria Angela Mura, Alessandra Perego, MD, Ester Maria Orlandi, MD, Mauro Turrini, MD, Lorenza Borin, MD, Maria Adele Capucci, MD, Alessandra Iurlo, MD PhD, Alessandra Trojani, PhD, Mariella D'Adda, MD, Francesco Spina, MD, Gabriella De Canal, Maria Luisa Pioltelli, Maria Luisa Latargia, MD, Sergio Pauli, MD, Chiara Elena, MD, Stefania Brusorio, Francesco Lanza, MD, Simona Malato, MD, Michela Anghilieri, MD, Maria C Carraro, MD, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2015) 126 (23): 1597.
https://doi.org/10.1182/blood.V126.23.1597.1597
Published: 2015