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Alan K. Burnett, MD
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Journal Articles

The Achievement of Complete Remission Is Associated with Improved Quality of Life in Non-Intensively Treated Patients with Acute Myeloid Leukemia: Results of the UK NCRI LI-1 Tria

Robert K. Hills, MA,DPhil,MSc, Ian Thomas, Alan K. Burnett, MD, Claire Jane Hemmaway, MD, Helen Dignum, Nigel H. Russell, Michael Dennis, MDMRCP,FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 372.
https://doi.org/10.1182/blood-2018-99-116173
Published: 2018
Journal Articles

Outcomes of Relapsed/Refractory Patients with IDH1/2 Mutated AML Treated with Non-Targeted Therapy: Results from the NCRI AML Trials

Robert K. Hills, MA,DPhil,MSc, Rosemary Gale, PhD, David C. Linch, Brian J.P Huntly, Elli Papaemmanuil, PhD, Paresh Vyas, Alan K. Burnett, MD, Nigel H. Russell
Journal: Blood
Blood (2018) 132 (Supplement 1): 664.
https://doi.org/10.1182/blood-2018-99-116482
Published: 2018
Journal Articles

Pre-Transplant NPM1 Mutant Transcript Level Is Highly Predictive of Outcome after Allograft and Thresholds Are Dependent on FLT3 ITD Status

Richard Dillon, MA, PhD MRCP, FRCPath, Robert K. Hills, MA, DPhil, MSc, Sylvie D Freeman, MBChB, DPhil, Nicola Potter, PhD, Adam Ivey, BSc, MSc, PhD, Jelena Jovanovic, PhD, Anju Kanda, MSc, Manohursingh Runglall, MSc, Nicola Foot, MSc, Laura Upton, Asim Khwaja, MD PhD, Jamie Cavenagh, MD PhD, Ruth Spearing, MD, Alan K. Burnett, MD, Nigel H. Russell, David Grimwade, PhD MRCP, MRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 2739.
https://doi.org/10.1182/blood-2018-99-113662
Published: 2018
Journal Articles

Outcomes in Relapsed/Refractory Patients with FLT3-ITD Mutated AML Are Poor When Treated with Non-Targeted Therapy with a Potential Role for Stem Cell Transplantation: Results from the NCRI AML Trials

Robert K. Hills, MA,DPhil,MSc, Alan K. Burnett, MD, Rosemary Gale, PhD, David C. Linch, Amanda Gilkes, Nigel H. Russell
Journal: Blood
Blood (2018) 132 (Supplement 1): 1392.
https://doi.org/10.1182/blood-2018-99-116542
Published: 2018
Journal Articles

A Knowledge-Based Approach for Clinical Annotation of Oncogenic Variants to Support Patient-Tailored Diagnosis in Myeloid Disease

Elsa Bernard, PhD, Kenichi Yoshida, MD PhD, Gunes Gundem, PhD, Jacob Grinfeld, MBChB, BSc, MRCP, FRCPath, Jyoti Nangalia, MBBChir, MA, MRCP, FRCPath, PhD, Daniel Leongamornlert, PhD, Noushin Farnoud, PhD, Juan Medina, Matahi Moarii, PhD, Charlie Massie, PhD, Yasunobu Nagata, MD PhD, Yusuke Okuno, MD PhD, Torsten Haferlach, MD, Seishi Ogawa, MD PhD, Amanda Gilkes, Oliver G. Ottmann, MD, Robert K. Hills, DPhil, Nigel H. Russell, Brian J.P Huntly, Anthony R Green, PhD FRCP, FRCPath, FMedSci, Alan K. Burnett, MD, Peter Campbell, PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1414.
https://doi.org/10.1182/blood.V130.Suppl_1.1414.1414
Published: 2017
Journal Articles

Characteristics and Outcome of Patients with Acute Myeloid Leukemia and t(6;9)(p22;q34)

Sabine Kayser, MD, Robert K. Hills, DPhil, Marlise R. Luskin, MD, Andrew M. Brunner, MD, Carole Shaw, Joerg Westermann, MD, Kamal Menghrajani, MD, Maria R. Baer, MD, Michelle A. Elliott, MD, Alexander E. Perl, MD, Christine Terré, PharmD, PhD, Zdenek Racil, MD, Jiri Mayer, Prof, MD SCs, Pavel Zak, MD, Tomas Szotkowski, MD, David Grimwade, Karin Mayer, MD, Roland B. Walter, MD PhD, Alwin Krämer, MD, Alan K. Burnett, MD, Anthony D. Ho, Richard M. Stone, MD, Martin S. Tallman, MD, Elihu H. Estey, MD, Carsten Müller-Tidow, Nigel H. Russell, Richard F. Schlenk, MD, Mark J. Levis, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3906.
https://doi.org/10.1182/blood.V130.Suppl_1.3906.3906
Published: 2017
Journal Articles

An Evaluation of 17 Years of Low Dose Cytarabine As Therapy for AML Patients Not Fit for Intensive Treatment, Including Patients with Adverse Cytogenetics, Shows Improving Survival, Potential Underutilisation and Highlights the Need for New Therapy

Michael Dennis, MDMRCP,FRCPath, Robert K. Hills, DPhil, Nigel H. Russell, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Ian Thomas, Mary Frances Frances McMullin, MB,Bch BAO, MD FRCPath, Sahra Ali, Alan K. Burnett, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3874.
https://doi.org/10.1182/blood.V130.Suppl_1.3874.3874
Published: 2017
Journal Articles

Flow Cytometric Minimal Residual Disease As Risk Stratification Tool in Younger Adults with NPM1 Wild Type Standard Risk Acute Myeloid Leukemia

Sylvie D Freeman, MBChB, DPhil, Robert K. Hills, DPhil, Paul Virgo, Naeem Khan, PhD, Stephen Couzens, Richard James Dillon, MA, PhD MRCP, FRCPath, Laura Upton, Lars Kjeldsen, MD, Ian Thomas, David Grimwade, Alan K. Burnett, MD, Nigel H. Russell
Journal: Blood
Blood (2017) 130 (Supplement 1): 468.
https://doi.org/10.1182/blood.V130.Suppl_1.468.468
Published: 2017
Journal Articles

A Randomised Assessment of Ganetespib Combined with Low Dose Ara-C Versus Low Dose Ara-C in Older Patients with Acute Myeloid Leukaemia: Results of the LI-1 Trial

Michael Dennis, FRCPath, Robert K Hills, DPhil, Ian Thomas, Sunil Gupta, MBBS, MRCP, FRCPath, Nicki Panoskaltsis, MD, Mhairi Copland, PhD BSc, MB, ChB, MRCP, FRCPath, Alan K. Burnett, MD FRCP, Nigel H Russell, MD
Journal: Blood
Blood (2016) 128 (22): 2827.
https://doi.org/10.1182/blood.V128.22.2827.2827
Published: 2016
Journal Articles

Long Term Follow up from the NCRI AML17 Trial of Attenuated Arsenic Trioxide and ATRA Therapy for Newly Diagnosed and Relapsed Acute Promyelocytic Leukaemia

Nigel H Russell, MD, Alan K. Burnett, MD FRCP, Robert K Hills, DPhil, Sophie Betteridge, PhD, Michael Dennis, FRCPath, Richard Dillon, MA, MRCP, FRCPath, David Grimwade, PhD FRCPath
Journal: Blood
Blood (2016) 128 (22): 897.
https://doi.org/10.1182/blood.V128.22.897.897
Published: 2016
Journal Articles

Quizartinib Significantly Improves Overall Survival in FLT3-ITD Positive AML Patients Relapsed after Stem Cell Transplantation or after Failure of Salvage Chemotherapy: A Comparison with Historical AML Database (UK NCRI data)

Robert K Hills, DPhil, Guy Gammon, MBBS,MRCP, Denise Trone, Alan K. Burnett, MD FRCP
Journal: Blood
Blood (2015) 126 (23): 2557.
https://doi.org/10.1182/blood.V126.23.2557.2557
Published: 2015
Journal Articles

A Comparison of 1 or 2 Courses of High Dose Cytarabine As Consolidation in Younger Patients with AML: First Results of the UK NCRI AML17 Trial

Nigel H. Russell, MD, Robert K Hills, DPhil, Sylvie Freeman, PhDFRCPath, Steven Knapper, Lars Kjeldsen, MD PhD, Ian Thomas, Jamie Cavenagh, Paul Cahalin, Mary Frances McMullin, MD FRCPath, FRCP, Alan K. Burnett, MD FRCP
Journal: Blood
Blood (2015) 126 (23): 221.
https://doi.org/10.1182/blood.V126.23.221.221
Published: 2015
Journal Articles

An Operational Definition of Primary Refractory Acute Myeloid Leukaemia Which Allows Early Identification of Patients for Whom Allogeneic Stem Cell Transplantation Represents the Only Curative Therapy

Paul Ferguson, MBChB MRCP PhD, Robert K Hills, DPhil, Angela Grech, Sophie Betteridge, Lars Kjeldsen, MD PhD, Michael Dennis, FRCPath, Paresh Vyas, MD PhD, Alan K. Burnett, MD FRCP, Anthony H. Goldstone, FRCP, FRCPath, Donald Milligan, MD, Richard E. Clark, MD, Nigel H. Russell, MD, Charles Craddock, MDPhD
Journal: Blood
Blood (2015) 126 (23): 559.
https://doi.org/10.1182/blood.V126.23.559.559
Published: 2015
Journal Articles

Prognostic Significance and Risk Stratification in Acute Myeloid Leukaemia Patients in the Absence of Successful Cytogenetic Analysis

Lucy Chilton, PhD, Christine Harrison, PhDFRCPath FMedSci, Anthony V. Moorman, PhD, Iona Ashworth, Alan K. Burnett, MD FRCP, David Grimwade, PhD FRCPath, Robert K Hills, MA MSc DPhil
Journal: Blood
Blood (2015) 126 (23): 1379.
https://doi.org/10.1182/blood.V126.23.1379.1379
Published: 2015
Journal Articles

The Impact of Different DNMT3A Mutations on Outcome in Younger Adults with Acute Myeloid Leukemia

Rosemary E Gale, Katarina Lamb, BSc, Christopher Allen, BSc, Dima El-Sharkawi, MBBS, Cassandra Stowe, MSc, Sarah Jenkinson, MSc, Steven Tinsley, PhD, Glenda Dickson, PhD, Alan K. Burnett, MD, Robert K. Hills, MA, MSc, DPhil, David C Linch, FMedSci
Journal: Blood
Blood (2014) 124 (21): 67.
https://doi.org/10.1182/blood.V124.21.67.67
Published: 2014
Journal Articles

A Randomised Comparison of Daunorubicin 90mg/m 2 Vs 60mg/m 2 in AML Induction: Results from the UK NCRI AML17 Trial in 1206 Patients

Alan K. Burnett, MD, Nigel Russell, Robert K. Hills, MA MSc DPhil, Jonathan Kell, MD MB, Jamie Cavenagh, Lars Kjeldsen, MD PhD, Mary Frances McMullin, MDFRCPath, FRCP, Paul Cahalin, Mike Dennis, Donald Milligan, MD, Richard E Clark, MBBS MD
Journal: Blood
Blood (2014) 124 (21): 7.
https://doi.org/10.1182/blood.V124.21.7.7
Published: 2014
Journal Articles

A Randomised Comparison of the Sequential Addition of the FLT3 Inhibitor Lestaurtinib (CEP701) to Standard First Line Chemotherapy for FLT3-Mutated Acute Myeloid Leukemia: The UK Experience

Steven Knapper, DM, Robert K Hills, MA MSc DPhil, James D Cavenagh, MD, Lars Kjeldsen, MDPhD, Ann E. Hunter, MBBS, Richard E Clark, MBBS MD, Michael Dennis, MD, Donald Milligan, MD, Mark J Levis, MDPhD, Nigel Russell, Alan K. Burnett, MD
Journal: Blood
Blood (2014) 124 (21): 3736.
https://doi.org/10.1182/blood.V124.21.3736.3736
Published: 2014
Journal Articles

A Randomised Assessment of Vosaroxin Monotherapy and Vosaroxin Combined with Low Dose Ara-C Versus Low Dose Ara-C in Older Patients with Acute Myeloid Leukaemia

Michael Dennis, MD, Nigel H. Russell, MD, Nicki Panoskaltsis, MD, Claire Jane Hemmaway, MD, Donald Milligan, MD, Richard E Clark, MBBS MD, Robert K. Hills, MA MSc DPhil, Alan K Burnett, MD
Journal: Blood
Blood (2014) 124 (21): 3747.
https://doi.org/10.1182/blood.V124.21.3747.3747
Published: 2014
Journal Articles

A Comparison of Single Dose Gemtuzumab Ozogamicin 3mg/m 2 and 6mg/m 2 Combined with Induction Chemotherapy in Younger Patients with AML: Data from the UK NCRI AML17 Trial

Alan K Burnett, MD, Nigel Russell, Robert K. Hills, MA MSc DPhil, Jamie Cavenagh, Jonathan Kell, MD MB, Gail Jones, Asim Khwaja, FRCPath, Mary Frances McMullin, MDFRCPath,FRCP, Mike Dennis, Donald Milligan, MD, Richard E Clark, MBBS MD
Journal: Blood
Blood (2014) 124 (21): 2308.
https://doi.org/10.1182/blood.V124.21.2308.2308
Published: 2014
Journal Articles

Integrated Nuclear Proteomics and Transcriptomics Identifies New High Frequency Dysregulated Transcription Factors in AML

Chinmay R Munje, BSc PhD, Andrew J. K. Williamson, BSc, PhD, Samuel Taylor, BSc, PhD, Robert K. Hills, MA, MSc, DPhil, Steven Knapper, DM BMBCh, Alan K. Burnett, MD, Andrew Pierce, BSc, PhD, Anthony Whetton, BSc, PhD, Richard L. Darley, BSc PhD, Alex Tonks, BSc PhD
Journal: Blood
Blood (2014) 124 (21): 3554.
https://doi.org/10.1182/blood.V124.21.3554.3554
Published: 2014