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Journal Articles

Loss of SWI/SNF Complex Subunit Arid1a in B Cells Promotes Inflammation and Perturbs Germinal Center B Cell Responses

Ajay Abraham, Daniela Samaniego-Castruita, Jillian Paladino, Mi Thao Tran, Isabella Goeun Han, Prathyaya Ramesh, Heather Kligfeld, Rebecca Southern, Ashima Shukla, Vipul Shukla
Journal: Blood
Blood (2023) 142 (Supplement 1): 1400.
https://doi.org/10.1182/blood-2023-189789
Published: 2023
Journal Articles

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Shaowei Qiu, MD, Chengcheng Yan, MD, Andrew J Paterson, PhD, Hui Li, BS, Nick Anderson, BS, Ajay Abraham, PhD, Jianbo He, MD, Mansi Shah, PhD, Puneet Agarwal, Jing Yang, PhD, Min Xie, MD, Rui Lu, PhD, Rob S. Welner, PhD, Ravi Bhatia, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2548.
https://doi.org/10.1182/blood-2019-124948
Published: 2019
Journal Articles

Tumor Suppressor Function of Dnmt3b in Hematologic Malignancies Critically Depends on Its Catalytic Activity

Katarina Lopusna, PhD, Pawel Nowialis, PhD, Staci L. Haney, PhD, Ajay Abraham, PhD, Jana Opavska, Rene Opavsky, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3788.
https://doi.org/10.1182/blood-2019-130857
Published: 2019
Journal Articles

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

Ajay Abraham, PhD, Shaowei Qiu, MD, Balu K Chacko, PhD, Hui Li, BS, Andrew J Paterson, PhD, Jianbo He, MD, Puneet Agarwal, PhD, Mansi Shah, PhD, Robert S. Welner, PhD, Victor M Darley-Usmar, PhD, Ravi Bhatia, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 932.
https://doi.org/10.1182/blood-2018-99-115709
Published: 2018
Journal Articles

Role of Enhanced Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Shaowei Qiu, MD, Andrew J Paterson, PhD, Ajay Abraham, PhD, Jianbo He, MD, Mansi Shah, PhD, Puneet Agarwal, PhD, Amanda K Mullen, Hui Li, BS, Mason W Harris, Nicholas R Anderson, Ravi Bhatia, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1358.
https://doi.org/10.1182/blood-2018-99-115702
Published: 2018
Journal Articles

Inhibition of CML Development Following Conditional SIRT1 Deletion in Transgenic BCR-ABL Mice

Ajay Abraham, PhD, Puneet Agarwal, MS, Hui Li, BS, Andrew Paterson, PhD, Jianbo He, MD, Ravi Bhatia, MD
Journal: Blood
Blood (2016) 128 (22): 931.
https://doi.org/10.1182/blood.V128.22.931.931
Published: 2016
Journal Articles

Role of NF-E2 Related Factor 2 (NRF2) on Chemotherapy Resistance in Acute Myeloid Leukemia (AML) and the Effect of Pharmacological Inhibition of NRF2

Sreeja Karathedath, MSc, Bharathi M Rajamani, M.Phil, Savitha Varatharajan, MSc, Ajay Abraham, MSc, Vikram Mathews, DM, Shaji R Velayudhan, PhD, Poonkuzhali Balasubramanian, PhD
Journal: Blood
Blood (2015) 126 (23): 1272.
https://doi.org/10.1182/blood.V126.23.1272.1272
Published: 2015
Journal Articles

Population Pharmacokinetics of Fludarabine and Treosulfan in Patients with Thalassemia Undergoing Hematopoietic Stem Cell Transplantation

Ezhil Pavai Mohanan, MSc, John C Panetta, PhD, Shareen Stella Backia Royan, BSc, Ajay Abraham, MSc, Eunice Sindhuvi Edison, PhD, Kavitha M Lakshmi, MSc, Fouzia Nambiathayil Abubacker, DM, Anu Korula, MD DM, Aby Abraham, MD DM, Auro Viswabandya, MD DM, Biju George, DM, Alok Srivastava, MD FRACP, Vikram Mathews, DM, Poonkuzhali Balasubramanian, PhD
Journal: Blood
Blood (2015) 126 (23): 3120.
https://doi.org/10.1182/blood.V126.23.3120.3120
Published: 2015
Journal Articles

Population Pharmacokinetics of Daunorubicin in AML: Influence on Clinical Outcome

Savitha Varatharajan, M.Sc, Ajay Abraham, M.Sc, John C Panetta, PhD, Sreeja Karathedath, M.Sc, Kavitha M Lakshmi, MSc, Chepsy C Philip, MD, Fouzia NA, MD, Abhijeet Ganapule, MD, Aby Abraham, MD, Auro Viswabandya, MD, Biju George, MD, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, PhD
Journal: Blood
Blood (2014) 124 (21): 902.
https://doi.org/10.1182/blood.V124.21.902.902
Published: 2014
Journal Articles

Harnessing Gene Expression Profiling In Search Of New Candidate Genes For Ara-C Resistance In Acute Myeloid Leukemia

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Shaji R Velayudhan, Ph.D, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D
Journal: Blood
Blood (2013) 122 (21): 1299.
https://doi.org/10.1182/blood.V122.21.1299.1299
Published: 2013
Journal Articles

Expression Profiling Of Nuclear Hormone Receptors In Myeloid Leukemia Reveals Potential Novel Drug Targets For Combination Therapy

Sreeja Karathedath, M.Sc, Sukanya Ganesan, M.Sc, Wei Zhang, PhD, Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Bharathi M Rajamani, MSc, M.Phil, Shaji R Velayudhan, Ph.D, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D
Journal: Blood
Blood (2013) 122 (21): 3855.
https://doi.org/10.1182/blood.V122.21.3855.3855
Published: 2013
Journal Articles

NPM1 Mutated AML Is Associated With Lower Expression Of Poor Prognostic Markers BAALC, ERG and MN1 In Adult Patients With Acute Myeloid Leukaemia

Poonkuzhali Balasubramanian, Ph.D, Ashok kumar Jayavelu, M.Sc, Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Senthamizhselvi Anandan, M.Sc, Vivi Srivastava, MD, Aby Abraham, MD, Auro Viswabandya, MD, Alok Srivastava, MD, Vikram Mathews, MD, DM
Journal: Blood
Blood (2013) 122 (21): 4945.
https://doi.org/10.1182/blood.V122.21.4945.4945
Published: 2013
Journal Articles

ABC Transporter Expression in Acute Myeloid Leukemia: Association with in Vitro Cytotoxicity and Prognostic Markers

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Ashok kumar Jeyavelu, M.Sc, Shaji R Velayudhan, M.Sc, Ph.D, Rayaz Ahmed, MD, Aby Abraham, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Vikram Mathews, Poonkuzhali Balasubramanian, Ph.D
Journal: Blood
Blood (2012) 120 (21): 1438.
https://doi.org/10.1182/blood.V120.21.1438.1438
Published: 2012
Journal Articles

Expression of Ara-C Metabolizing Enzymes Mediates in Vitro Sensitivity to Ara-C in Primary AML Cells From Patients with Denovo AML,

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Ashok kumar Jayavelu, M.Sc, Shaji R Velayudhan, M.Sc, Ph.D, Rayaz Ahmed, MD, Aby Abraham, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, M.Sc., Ph.D
Journal: Blood
Blood (2011) 118 (21): 3481.
https://doi.org/10.1182/blood.V118.21.3481.3481
Published: 2011
Journal Articles

Carbonyl Reductase 1 Expression and Polymorphisms Influence Daunorubicin Metabolism in AML

Savitha Varatharajan, M.Sc, Ajay Abraham, M.Sc, Shaji R Velayudhan, M.Sc, Ph.D, Rayaz Ahmed, MD, Aby Abraham, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D
Journal: Blood
Blood (2011) 118 (21): 2484.
https://doi.org/10.1182/blood.V118.21.2484.2484
Published: 2011