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Adam Sperling, MD, PhD
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Journal Articles

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

Weihua Song, MD, Chaolin Zhang, PhD, Yiguo Hu, PhD, Maria Gkotzamanidou, MD PhD, Parantu Shah, Weisong Shan, MDPhD, Guang Yang, PhD, Yi Li, Adam Sperling, MD PhD, Naim Rashid, PhD, Mehmet Kemal Samur, PhD, Samir B. Amin, MBBS, Yu-Tzu Tai, Teru Hideshima, MDPhD, Giovanni Parmigiani, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Hervé Avet-Loiseau, MD PhD, Kenneth C. Anderson, Cheng Li, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 4714.
https://doi.org/10.1182/blood.V124.21.4714.4714
Published: 2014
Journal Articles

A Next Generation Sequencing-Based Approach to Detect Gene Mutations, Copy Number Changes and IGH Translocations in Multiple Myeloma

Niccolo Bolli, MD PhD, Graham R Bignell, PhD, Peter Ganly, BMBCh, PhD, Elli Papaemmanuil, PhD, Herve Avet-Loiseau, Adam Sperling, MD PhD, Stephane Minvielle, Peter J Campbell, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 3364.
https://doi.org/10.1182/blood.V124.21.3364.3364
Published: 2014
Journal Articles

Alternative Splicing Is a Frequent Event and Impacts Clinical Outcome in Myeloma: A Large RNA-Seq Data Analysis of Newly-Diagnosed Myeloma Patients

Naim Rashid, PhD, Stephane Minvielle, Florence Magrangeas, Mehmet Kemal Samur, PhD, Alice Clynen, PhD, Adam Sperling, MD PhD, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Paul G. Richardson, Michel Attal, Philippe Moreau, Kenneth C. Anderson, Giovanni Parmigiani, PhD, Hervé Avet-Loiseau, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 638.
https://doi.org/10.1182/blood.V124.21.638.638
Published: 2014
Journal Articles

Differential and Limited Expression of Mutant Alleles in Multiple Myeloma

Adam Sperling, MD PhD, Naim Rashid, PhD, Niccolo Bolli, MD PhD, David Wedge, PhD, Peter Van Loo, PhD, Yu-Tzu Tai, Masood Shammas, PhD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Paul G. Richardson, Florence Magrangeas, Stephane Minvielle, P Andrew Futreal, Kenneth C. Anderson, Herve Avet-loiseau, Peter J. Campbell, PhD, Giovanni Parmigiani, PhD, Nikhil Munshi
Journal: Blood
Blood (2014) 124 (21): 2007.
https://doi.org/10.1182/blood.V124.21.2007.2007
Published: 2014
Journal Articles

Long Intergenic Non-Coding RNAs (lincRNA) Impacts Biology and Clinical Outcome in Multiple Myeloma

Mehmet Kemal Samur, PhD, Naim Rashid, PhD, Alice Cleynen, PhD, Mariateresa Fulciniti, PhD, Adam Sperling, MD PhD, Stephane Minvielle, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Hervé Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 642.
https://doi.org/10.1182/blood.V124.21.642.642
Published: 2014
Journal Articles

Multiple Myeloma Cells Express IL-17A Creating An Autocrine Loop: An Attractive Therapeutic Target

Rao H. Prabhala, Ph.D., Mariateresa Fulcinitti, PhD, Dheeraj Pelluru, PhD, Harsha K. Prabhala, MS, Naim Rashid, PhD, Adam Sperling, MD, PhD, Puru Nanjappa, MS, Saem Lee, B.A., Andreea Negroiu, MD, Suzan Lazo-Kallanian, BS, Aditya Munshi, MD, Paul G. Richardson, MD, John Daley, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2013) 122 (21): 3113.
https://doi.org/10.1182/blood.V122.21.3113.3113
Published: 2013
Journal Articles

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

Weihua Song, MD, Chaolin Zhang, PhD, Yiguo Hu, PhD, Maria Gkotzamanidou, MD, Parantu Shah, PhD, Weisong Shan, MD PhD, Guang Yang, PhD, Samir B. Amin, MBBS, Yu-Tzu Tai, PhD, Yi Li, PhD, Adam Sperling, MD, PhD, Naim Rashid, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Hervé Avet-Loiseau, MD, PhD, Kenneth C. Anderson, MD, Cheng Li, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2013) 122 (21): 3085.
https://doi.org/10.1182/blood.V122.21.3085.3085
Published: 2013
Journal Articles

Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution

Niccolo Bolli, MD, PhD, Herve Avet-Loiseau, MD, David Wedge, Peter Van Loo, PhD, Ludmil Alexandrov, Inigo Martincorena, Kevin Dawson, Francesco Iorio, Serena Nik-Zainal, Graham R Bignell, Jonathan Hinton, Jose Tubio, Stuart McLaren, O'Meara Sarah, Adam Butler, Teague Jon, Laura J Mudie, Yu-Tzu Tai, PhD, Masood Shammas, PhD, Adam Sperling, MD, PhD, Mariateresa Fulciniti, PhD, Paul G. Richardson, MD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Philippe Moreau, MD, Michel Attal, MD, Andy Futreal, PhD, Thierry Facon, MD, Kenneth C. Anderson, MD, Peter J. Campbell, PhD, Nikhil Munshi, MD
Journal: Blood
Blood (2013) 122 (21): 399.
https://doi.org/10.1182/blood.V122.21.399.399
Published: 2013