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Francesco Iorio
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Journal Articles

An unbiased lncRNA dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a novel therapeutic target for multiple myeloma

Katia Grillone, Serena Ascrizzi, Paolo Cremaschi, Jussara Amato, Nicoletta Polerà, Ottavio Croci, Roberta Rocca, Caterina Riillo, Francesco Conforti, Raffaele Graziano, Diego Brancaccio, Daniele Caracciolo, Stefano Alcaro, Bruno Pagano, Antonio Randazzo, Pierosandro Tagliaferri, Francesco Iorio, Pierfrancesco Tassone
Journal: Blood
Blood (2024) 144 (16): 1705–1721.
https://doi.org/10.1182/blood.2023021991
Published: 2024
Includes: Supplemental data
Journal Articles

A Crispr/Cas9 Drop-out Screen Identifies Genome-Wide Genetic Valnerubilities in Acute Myeloid Leukaemia

Konstantinos Tzelepis, MSc, Hiroko Koike-Yusa, MD, Etienne De Braekeleer, PhD, Yilong Li, Emmanouil Metzakopian, PhD, Oliver M. Dovey, PhD, Annalisa Mupo, PhD, Vera Grinkevich, PhD, Milena M. Mazan, PhD, Malgorzata Gozdecka, PhD, Jonathan L. Cooper, Miten Patel, MD, Thomas David Hardman McKerrell, MD, Bin Chen, Hannes Ponstingl, PhD, Brian J.P Huntly, MD PhD, Ultan McDermott, MD PhD, Julio Saez-Rodriguez, PhD, Francesco Iorio, PhD, Kosuke Yusa, PhD, George S. Vassiliou, MD PhD
Journal: Blood
Blood (2015) 126 (23): 554.
https://doi.org/10.1182/blood.V126.23.554.554
Published: 2015
Journal Articles

Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution

Niccolo Bolli, MD, PhD, Herve Avet-Loiseau, MD, David Wedge, Peter Van Loo, PhD, Ludmil Alexandrov, Inigo Martincorena, Kevin Dawson, Francesco Iorio, Serena Nik-Zainal, Graham R Bignell, Jonathan Hinton, Jose Tubio, Stuart McLaren, O'Meara Sarah, Adam Butler, Teague Jon, Laura J Mudie, Yu-Tzu Tai, PhD, Masood Shammas, PhD, Adam Sperling, MD, PhD, Mariateresa Fulciniti, PhD, Paul G. Richardson, MD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Philippe Moreau, MD, Michel Attal, MD, Andy Futreal, PhD, Thierry Facon, MD, Kenneth C. Anderson, MD, Peter J. Campbell, PhD, Nikhil Munshi, MD
Journal: Blood
Blood (2013) 122 (21): 399.
https://doi.org/10.1182/blood.V122.21.399.399
Published: 2013