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Journal Articles

A Phase 1 Clinical Trial of NKTR-255 with CD19-22 CAR-T Cell Therapy for Refractory B-cell Acute Lymphoblastic Leukemia

Clinical Trials & Observations
Hrishikesh Krishna Srinagesh, Clayton Jackson, Parveen Shiraz, Nikeshan Jeyakumar, Mark P Hamilton, Emily Egeler, Sharon Mavroukakis, Adam Kuo, Juancarlos Cancilla, Bita Sahaf, Neha Agarwal, Alyssa M Kanegai, Anne Marijn Kramer, Sally Arai, Sushma Bharadwaj, Saurabh Dahiya, Hitomi Hosoya, Laura J Johnston, Vanessa E Kennedy, Michaela Liedtke, Robert Lowsky, Lekha Mikkilineni, Robert S. Negrin, Andrew R. Rezvani, Surbhi Sidana, Judith A. Shizuru, Melody Smith, Wen-Kai Weng, Steven A Feldman, Matthew J. Frank, Zachary Lee, Mary Tagliaferri, A Mario Q. Marcondes, David B Miklos, Crystal L. Mackall, Lori Muffly
Journal: Blood
Blood blood.2024024952.
https://doi.org/10.1182/blood.2024024952
Published: 2024
Includes: Supplemental data
Journal Articles

Interim Results of a Phase 1b/2 Study of Entospletinib (GS-9973) Monotherapy and in Combination with Chemotherapy in Patients with Acute Myeloid Leukemia

Alison R. Walker, MD MPH, Bhavana Bhatnagar, DO, A. Mario Q. Marcondes, MD, Julie DiPaolo, PhD, Sumithra Vasu, MBBS, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Katherine J. Walsh, MD, Renee Canning, RN, Gregory K. Behbehani, MD PhD, Ramiro Garzon, MD, James S. Blachly, MD, Amy J. Johnson, PhD, Esteban Abella-Dominicis, John C. Byrd, MD, William Blum, MD
Journal: Blood
Blood (2016) 128 (22): 2831.
https://doi.org/10.1182/blood.V128.22.2831.2831
Published: 2016
Journal Articles

Myelodysplastic Syndrome Marrow Stroma Shows Widespread Aberrant Hypermethylation That Is Abrogated By Treatment with Dnmt Inhibitors

Tushar D Bhagat, PhD, Matthias Bartenstein, MD, Yiting Yu, PhD, A. Mario Q. Marcondes, MD PhD, Britta Will, PhD, Orsolya Giricz, PhD, Davendra P. Sohal, MD MPH, Ioannis Mantzaris, MD, Amittha Wickrema, PhD, Christine Mcmahon, MD, Yeung Cecilia, MD, John Greally, MB, PhD, Siddhartha Mukherjee, MD PhD, Ulrich Steidl, MD PhD, H. Joachim Deeg, MD, Amit Verma, MD
Journal: Blood
Blood (2014) 124 (21): 4379.
https://doi.org/10.1182/blood.V124.21.4379.4379
Published: 2014
Journal Articles

Alpha 1 Anti-Trypsin (AAT) Offers Potent Therapy for Steroid Resistant Gut Gvhd: Interim Results of a Phase I/II Clinical Study

A. Mario Q. Marcondes, MD PhD, Mohamed L. Sorror, MD, Ekapun Karoopongse, MD, Terry Furlong, NP, Marina Lesnikova, PhD, Sabina Janciauskiene, MD, Charles A. Dinarello, MD, H. Joachim Deeg, MD
Journal: Blood
Blood (2014) 124 (21): 3927.
https://doi.org/10.1182/blood.V124.21.3927.3927
Published: 2014
Journal Articles

The Jumanjii Histone Demethylase KDM2B controls EZH2 Expression In Myelodysplastic Syndromes (MDS) Via Mir Let-7b (let7b), a Pathway That Is Bypassed By The Histone Methylation Inhibitor DZNep

Ekapun Karoopongse, MD, John Byon, MD, PhD, Cecilia Yeung, MD, H. Joachim Deeg, MD, A. Mario Q. Marcondes, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1543.
https://doi.org/10.1182/blood.V122.21.1543.1543
Published: 2013
Journal Articles

Donor Treatment with α1 Anti-Trypsin (AAT) Mitigates Gvhd and Increases Survival While Sparing GVL Effects

A. Mario Q. Marcondes, MD, PhD, Ekapun Karoopongse, MD, Marina Lesnikova, PhD, Sabina Janciauskiene, MD, Charles A. Dinarello, M.D., H. Joachim Deeg, MD
Journal: Blood
Blood (2012) 120 (21): 1889.
https://doi.org/10.1182/blood.V120.21.1889.1889
Published: 2012
Journal Articles

α1 Anti-Trypsin (AAT) Mitigates Hematopoietic Injury and Enhances Bone Marrow Recovery After Total Body Irradiation (TBI)

Ekapun Karoopongse, MD, Sabina Janciauskiene, MD, Charles A. Dinarello, M.D., H. Joachim Deeg, A. Mario Q. Marcondes, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4142.
https://doi.org/10.1182/blood.V120.21.4142.4142
Published: 2012
Journal Articles

Interleukin-32, α1 Anti-Trypsin (AAT-1) and Graft-Versus-Host-Disease

A. Mario Q. Marcondes, MD, PhD, Laura Tabellini, John A. Hansen, MD, Charles A. Dinarello, MD, H. Joachim Deeg, MD
Journal: Blood
Blood (2010) 116 (21): 522.
https://doi.org/10.1182/blood.V116.21.522.522
Published: 2010
Journal Articles

Identification of DJ-1/Park-7 as a Determinant of Tnfα-Induced and Stroma-Dependent Apoptosis in Leukemia Using Mass Spectometry and Phosphopetide Analysis.

A. Mario Q. Marcondes, MD, Li Xiang, Brian P Milless, H. Joachim Deeg
Journal: Blood
Blood (2008) 112 (11): 1796.
https://doi.org/10.1182/blood.V112.11.1796.1796
Published: 2008