Schwartz CL, Constine LS, Villaluna D, et al. A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425. Blood. 2009;114(10):2051-2059.

doi:10.1182/blood-2016-06-723056

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ERRATA| July 28, 2016

Schwartz CL, Constine LS, Villaluna D, et al. A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425. Blood. 2009;114(10):2051-2059.

Blood (2016) 128 (4): 605.

https://doi.org/10.1182/blood-2016-06-723056

In Table 5 on page 2056 in the 3 September 2009 issue, the data for cases of typhlitis in patients not treated with dexrazoxane and in those treated with dexrazoxane are transposed. The corrected Table 5 is shown below.

2016

Table 5

Grade 3 and 4 toxicity with or without dexrazoxane

	Without dexrazoxane		With dexrazoxane
	Count (n = 108)	Incidence, %	Count (n = 106)	Incidence, %
ANC grade 4*	84	77.8	99	93.4
ANC grade 3	9	8.3	1	0.9
Platelets*	32	29.6	77	72.6
Hemoglobin*	44	40.7	64	60.4
Thrombosis*	1	0.9	4	3.8
Infection, not otherwise specified/unknown*	48	44.4	75	70.8
Sepsis*	9	8.4	18	17.0
Typhlitis	3	2.8	9	8.5
Pulmonary*†	3	2.8	13	12.3
Cardiac function	2	1.9	0	0
Peripheral nervous system/central nervous system‡	3/0	2.8/0	2/1	1.9/0.9
Stomatitis	31	28.7	30	28.3
Vomiting/nausea	10	9.3	10	9.4
Allergic reaction	2	1.9	7	6.6
Secondary malignancy	1	0.9	3	2.8

	Without dexrazoxane		With dexrazoxane
	Count (n = 108)	Incidence, %	Count (n = 106)	Incidence, %
ANC grade 4*	84	77.8	99	93.4
ANC grade 3	9	8.3	1	0.9
Platelets*	32	29.6	77	72.6
Hemoglobin*	44	40.7	64	60.4
Thrombosis*	1	0.9	4	3.8
Infection, not otherwise specified/unknown*	48	44.4	75	70.8
Sepsis*	9	8.4	18	17.0
Typhlitis	3	2.8	9	8.5
Pulmonary*†	3	2.8	13	12.3
Cardiac function	2	1.9	0	0
Peripheral nervous system/central nervous system‡	3/0	2.8/0	2/1	1.9/0.9
Stomatitis	31	28.7	30	28.3
Vomiting/nausea	10	9.3	10	9.4
Allergic reaction	2	1.9	7	6.6
Secondary malignancy	1	0.9	3	2.8

Significant grade 3 toxicities that occurred in more than 5% of patients, all grade 4 toxicities, and specific targeted toxicities (pulmonary, cardiac, peripheral nervous system) are included above. Except as specified (eg, ANC), the numbers represent combined grade 3 and grade 4 toxicities.

ANC indicates absolute neutrophil count.

Statistically significantly different (log-rank test, P ≤ .05).

†

Includes diffusion capacity for carbon monoxide, vital capacity, pulmonary/functional, and oxygen saturation.

‡

Central nervous system includes mood, cortical, and cerebellar.

Schwartz CL, Constine LS, Villaluna D, et al. A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425. Blood. 2009;114(10):2051-2059.

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Schwartz CL, Constine LS, Villaluna D, et al. A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425. Blood. 2009;114(10):2051-2059.

Contents

Data & Figures

Supplemental data

References

Related

Related

Cited By

Email alerts

ASH Publications

American Society of Hematology

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