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Letter to Blood|
January 25, 2024
Characterization of reverse-engineered anti-PF4 stereotypic antibodies derived from serum of patients with VITT
Jing Jing Wang,
Jing Jing Wang
1Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia
2Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, SA, Australia
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Marijn van der Neut Kolfschoten,
Marijn van der Neut Kolfschoten
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Lucy Rutten,
Lucy Rutten
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Bridie Armour,
Bridie Armour
1Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia
2Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, SA, Australia
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Chee Wee Tan,
Chee Wee Tan
4Department of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia
5Department of Hematology, SA Pathology, Adelaide, SA, Australia
6Department of Hematology, Royal Adelaide Hospital, Central Area Local Health Network, Adelaide, SA, Australia
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Tim Chataway,
Tim Chataway
7Flinders Proteomics Facility, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia
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Rinke Bos,
Rinke Bos
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Annemart Koornneef,
Annemart Koornneef
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Pravien Abeywickrema,
Pravien Abeywickrema
8Structural & Protein Sciences, Janssen Research and Development, Spring House, PA
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Rick Kapur,
Rick Kapur
9Sanquin Research, Department of Experimental Immunohematology, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
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Leendert Porcelijn,
Leendert Porcelijn
10Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, The Netherlands
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Midia Khalifa,
Midia Khalifa
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Ava Sadi,
Ava Sadi
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Pascale Bouchier,
Pascale Bouchier
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Eleni Kourkouta,
Eleni Kourkouta
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Aditya Perkasa,
Aditya Perkasa
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Ted Kwaks,
Ted Kwaks
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Roland Zahn,
Roland Zahn
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Laura Solforosi,
Laura Solforosi
3Janssen Vaccines & Prevention B.V., Leiden, The Netherlands
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Tom P. Gordon
Tom P. Gordon
1Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia
2Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, SA, Australia
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Blood (2024) 143 (4): 370–374.
Article history
Submitted:
May 26, 2023
Accepted:
October 31, 2023
First Edition:
November 17, 2023
Connected Content
A commentary has been published:
Deciphering VITT’s dangerous code
Citation
Jing Jing Wang, Marijn van der Neut Kolfschoten, Lucy Rutten, Bridie Armour, Chee Wee Tan, Tim Chataway, Rinke Bos, Annemart Koornneef, Pravien Abeywickrema, Rick Kapur, Leendert Porcelijn, Midia Khalifa, Ava Sadi, Pascale Bouchier, Eleni Kourkouta, Aditya Perkasa, Ted Kwaks, Roland Zahn, Laura Solforosi, Tom P. Gordon; Characterization of reverse-engineered anti-PF4 stereotypic antibodies derived from serum of patients with VITT. Blood 2024; 143 (4): 370–374. doi: https://doi.org/10.1182/blood.2023021307
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January 25 2024
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