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Clotting Disorders Free

December 20, 2021

A collection of features and news articles published in ASH Clinical News related to clotting disorders.

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Study Shows Modest Increased Risk of VTE in Patients With CHIP

Results of a cohort study on clonal hematopoiesis of indeterminate potential (CHIP) demonstrate that it may modestly increase the risk of venous thromboembolism ...

Half of Patients in EINSTEIN Jr. Trial Continue to Extended Anticoagulation Treatment

Half of the children with venous thromboembolism (VTE) opted to continue anticoagulation therapy after participating in the extended-phase anticoagulation cohort of ...

Use of GLP-1 Agonists in Diabetic Patients With PV, ET Reduces VTE, Mortality

The use of glucagon-like peptide-1 receptor agonists (GLP-1a) in patients with type II diabetes mellitus (T2DM) who had essential thrombocythemia (ET) or polycythemia vera ...

Caplacizumab Combo a ‘Historic’ New Option for Non-Severe iTTP

Caplacizumab in combination with immunosuppressive therapy given without therapeutic plasma exchange (TPE) was a safe and effective treatment for patients with acute immune ...

Prophylactic Anticoagulation Reduces Death, VTE in Patients With Cancer

Prophylactic anticoagulation can mitigate the risk of venous thromboembolism (VTE) in patients with cancer who are at high risk for VTE; however, “there’s a paucity of data ...

FDA to Give Narsoplimab Second Look for Treatment of HSCT-Associated Thrombotic Microangiopathy

In a 28-patient single-arm study, which took place between August 2015 and January 2020, patients with HSCT-TMA received narsoplimab once weekly for four to eight weeks ...

Use of ACR/EULAR 2023 Criteria Results in Lower APS Diagnosis Rate Compared With Sydney Criteria

Use of the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) 2023 criteria, which were developed to refine the classification ...

Relapse-Free Survival Progressively Shortens in Black Patients With Rituximab-Treated iTTP

In patients with relapsing immune thrombotic thrombocytopenic purpura (iTTP), successive rituximab treatment shortens relapse-free survival (RFS), a finding most pronounced ...

CRP Levels May Help Stratify VTE Risk in Patients With Cancer on ICIs

C-reactive protein (CRP) levels may help identify patients on immune checkpoint inhibitors (ICIs) who are at increased risk of venous thromboembolism (VTE) ...

Reduced Dose of DOACs May Reduce Bleeding, Health Care Usage in VTE Management

During the 66th American Society of Hematology Annual Meeting and Exposition, Jordan K. Schaefer, MD, MSc, of the University of Michigan in Ann Arbor ...

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