Marstacimab Provides New Prophylactic Option for Hemophilia A, B
The impressive results of the phase III trial of marstacimab, pivotal for the U.S. Food and Drug Administration (FDA) approval of the treatment last fall, are now available ...
Phase IIIb Results Show Avatrombopag to Be Safe, Effective Treatment for Children With ITP
Results from the phase IIIb AVA-PED-301 trial indicate that avatrombopag is an effective oral treatment for children and adolescents with a confirmed diagnosis of immune thrombocytopenia ...
Daratumumab Shows Efficacy, Safety in Phase II Study of Previously Treated ITP
For patients with previously treated immune thrombocytopenia (ITP), the anti-CD38 antibody daratumumab showed an acceptable safety profile and potential for efficacy in a multicenter ...
Concizumab Reduced Annualized Bleeding Rates in Hemophilia A, B Regardless of Target Joints
In patients with hemophilia A or B, once-daily subcutaneous concizumab prophylaxis effectively reduced the annualized bleeding rate (ABR) compared with on-demand ...
Marstacimab Shows Long-Term Efficacy in Severe Hemophilia A, B Without Inhibitors
In adults and adolescents with severe hemophilia A or B without inhibitors, the anti-tissue factor pathway inhibitor marstacimab, delivered once-weekly subcutaneously ...
Exploring Heterozygote Bleeding Risk in Rare Bleeding Disorders
A retrospective study from the Netherlands, published in the Journal of Thrombosis and Haemostasis, highlights the need to diagnose and properly manage heterozygote patients ...
Nurse-Led Multidisciplinary Pathway Developed to Optimize Patient Journey in Acquired Hemophilia A
Patients with acquired hemophilia A, a severe bleeding disorder associated with high morbidity and mortality, require an experienced and knowledgeable multidisciplinary team ...
Another Potential Product for Fibrinogen Concentrate for Congenital Fibrinogen Deficiency
A poster presented at this year’s European Hematology Association Congress reported on a successful phase III trial of BT524, a human plasma-derived fibrinogen concentrate for ...
Iron Deficiency Potentially Underdiagnosed in Females With Bleeding Disorders
Findings from an observational study published in Haemophilia indicate that providers may be insufficiently screening — and thus undertreating — iron deficiency ...
