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Journal Articles

Novel humanized loss-of-function NF1 mouse model of juvenile myelomonocytic leukemia

Open Access
Roshani Sinha, Rachana V Patil, Rosa Romano, Devesh Sharma, Esmond Lee, Rhonda Perriman, Saori Takeda, Benjamin J Lesch, Zhenyu Yao, Y. Lucy Liu, M. Kyle Cromer, Matthew H Porteus, Alice Bertaina
Journal: Blood Advances
Blood Adv bloodadvances.2024015191.
https://doi.org/10.1182/bloodadvances.2024015191
Published: 2025
Includes: Supplemental data
Journal Articles

Vaccine-educated T cells and a CD123 bispecific T-cell engager for treatment of acute myeloid leukemia

Open Access
Jessica Liegel, Dina Stroopinsky, Giulia Cheloni, Dimitra Karagkouni, Myrna Nahas, Yuling Ma, Daniela Torres, Isabella Saldarriaga, Shuoshuo Wang, Antonella Arruda de Amaral, Athanasios Ploumakis, John Clohessy, Joseph Abirached, Lina Bisharat, Paula Fraenkel, Ozlem Yildirim, Hélène Bonnevaux, Stephane Guerif, Katie Rallis, Georges Chedid, Donald Kufe, Ioannis S. Vlachos, David Avigan, Jacalyn Rosenblatt
Journal: Blood Advances
Blood Adv (2025) 9 (21): 5585–5597.
https://doi.org/10.1182/bloodadvances.2024015449
Published: 2025
Includes: Supplemental data
Journal Articles

Preclinical efficacy of tasquinimod-based combinations in advanced myeloproliferative neoplasms in blastic phase

Open Access
Warren Fiskus, Lucia Masarova, Christopher P. Mill, Christine E. Birdwell, Kaberi Das, Hanxi Hou, John A. Davis, Antrix Jain, Anna Malovannaya, Taghi Manshouri, Andrew Dunbar, Surbhi Sharma, Tapan M. Kadia, Courtney D. DiNardo, Prithviraj Bose, Naveen Pemmaraju, Sanam Loghavi, Xiaoping Su, Raajit K. Rampal, Marie Törngren, Kapil N. Bhalla
Journal: Blood Advances
Blood Adv (2025) 9 (21): 5598–5609.
https://doi.org/10.1182/bloodadvances.2025016898
Published: 2025
Includes: Supplemental data
Journal Articles

Metformin induces ferroptosis associated with lipidomic remodeling in AML

Open Access
Dominique Sternadt, Diego A Pereira-Martins, Prodromos Chatzikyriakou, Luise Albuquerque-Simões, Ming Yang, Douglas R Silveira, Albertus TJ Wierenga, Isabel Weinhäuser, Shanna M. Hogeling, Lieve Oudejans, Pilar Casares-Alaez, Jean-Emmanuel Sarry, Christian Frezza, Gerwin A Huls, Lynn Quek, Jan Jacob Schuringa
Journal: Blood Advances
Blood Adv bloodadvances.2025016155.
https://doi.org/10.1182/bloodadvances.2025016155
Published: 2025
Includes: Supplemental data
Journal Articles

Long-term Efficacy and Safety of Ropeginterferon Alfa-2b under its HIDAT Regimen for the Treatment of Polycythemia Vera

Open Access
Shanshan Suo, Rongfeng Feng Fu, Albert Qin, Dr., Zonghong Shao, Jie Bai, Hu Zhou, Na Xu, Suning Chen, Xuelan Zuo, Xin Du, Minghui Duan, Li Wang, Pei Li, Xuhan Zhang, Sujiang Zhang, Daoxiang Wu, Jingjing Zhang, Zhijian Xiao, Lei Zhang, Jie Jin
Journal: Blood Advances
Blood Adv bloodadvances.2025017938.
https://doi.org/10.1182/bloodadvances.2025017938
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of radiotherapy site, modality, and dose on subsequent clonal hematopoiesis

Open Access
Alexander G. Goglia, Griffen R. Mustion, Leslie A. Modlin, Ross L. Levine, Kelly L. Bolton, Lior Z. Braunstein
Journal: Blood Advances
Blood Adv (2025) 9 (21): 5564–5567.
https://doi.org/10.1182/bloodadvances.2025016376
Published: 2025
Includes: Supplemental data
Journal Articles

Overcoming venetoclax resistance through heme-mediated NOXA/cyclin D1/Mcl-1 axis with a novel artemisinin conjugate

Open Access
Jingyi Zhang, Zhenwei Zhang, Jinghua Liu, Shenglin Luan, Jiqiang Qu, Zi Wu, Yafei Kuang, Ping Gong, Yu Bao, Yuetong Wang, Xiaojing Yan, Samuel Waxman, Linxiang Zhao, Yongkui Jing
Journal: Blood Advances
Blood Adv (2025) 9 (21): 5473–5488.
https://doi.org/10.1182/bloodadvances.2025015806
Published: 2025
Includes: Supplemental data
Journal Articles

OPTICAL GENOME MAPPING IN MYELOFIBROSIS: ENHANCING PROGNOSTIC ACCURACY THROUGH HIGH-RESOLUTION GENOMIC PROFILING.

Open Access
Álvaro Díaz González, Elvira Mora, Marta Garrote, Gonzalo Carreño-Tarragona, Marta Salido Galeote, Irene Pastor-Galán, Ruth Stuckey, Adela Cisneros Sala, Jose Antonio Domingo-Monfort, Nerea Uresandi, Nagore Argoitia-Ituarte, Gayane Avetisyan, Cristian Garcia-Ruiz, Neus Torres Hernandez, Santiago Furió, Eduardo Arellano-Rodrigo, Noemí Álvarez, Patricia Velez, Eva Villamon, Adrián Segura-Díaz, Rosa Ayala, Blanca Espinet, Alberto Álvarez-Larrán, Juan Carlos Hernandez-Boluda, Esperanza Such
Journal: Blood Advances
Blood Adv bloodadvances.2025017980.
https://doi.org/10.1182/bloodadvances.2025017980
Published: 2025
Includes: Supplemental data
Journal Articles

Molecular Risk Markers Define Risk of Relapse in Myeloid Leukemia of Down syndrome Beyond Measurable Residual Disease

Open Access
Jason N Berman, Anupam Verma, Shelton A. Viola, Todd Alonzo, Yi-Cheng Wang, Lisa Eidenschink Brodersen, Michael R Loken, Amy K. Beckman, Betsy A Hirsch, Susana Raimondi, Karen M. Chisholm, Xiaotu Ma, Rhonda E. Ries, Soheil Meshinchi, Alan S Gamis, Reuven J Schore, Jeffrey W. Taub, E Anders Kolb, Todd M Cooper, Johann K. Hitzler
Journal: Blood Advances
Blood Adv bloodadvances.2025017837.
https://doi.org/10.1182/bloodadvances.2025017837
Published: 2025
Includes: Supplemental data
Journal Articles

Olutasidenib: an Achilles’ heel for IDH1 -mutated MDS?

Open Access
Clinical Trials & Observations
Laura Wiser, Curtis Lachowiez
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5341–5342.
https://doi.org/10.1182/bloodadvances.2025017582
Published: 2025
Journal Articles

Olutasidenib alone or combined with azacitidine in patients with mutant IDH1 myelodysplastic syndrome

Open Access
Clinical Trials & Observations
Jorge E. Cortes, Jay Yang, Gail J. Roboz, Shira N. Dinner, Eunice S. Wang, Andrew H. Wei, Hua Tian, Francois di Trapani, Maria R. Baer, William Donnellan, Justin M. Watts
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5293–5305.
https://doi.org/10.1182/bloodadvances.2025016718
Published: 2025
Includes: Supplemental data
Journal Articles

Somatic mutations in STAG2 are associated with separated megakaryocyte nuclear lobes in myelodysplastic syndromes

Open Access
Waihay J. Wong, Rebecca L. Zon, Christopher J. Gibson, Caleb Ho, Olga Pozdnyakova, Donna Neuberg, Elisabeth M. Battinelli, Marlise R. Luskin, Zuzana Tothova, Elizabeth A. Morgan, Benjamin L. Ebert
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5283–5288.
https://doi.org/10.1182/bloodadvances.2025016897
Published: 2025
Includes: Supplemental data
Journal Articles

Embarrassment of riches: which donor for allo-transplant?

Open Access
Clinical Trials & Observations
Eric Irons, Koen van Besien
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5247–5248.
https://doi.org/10.1182/bloodadvances.2025017295
Published: 2025
Journal Articles

Older matched sibling donor vs young haploidentical donor for older patients with acute myeloid leukemia

Open Access
Clinical Trials & Observations
Xavier Poiré, Myriam Labopin, Emmanuelle Polge, Didier Blaise, Patrice Chevallier, Johan Maertens, Nicolaus Kröger, Caroline Besley, Stéphanie Nguyen, Cristina Castilla-Llorente, Gérard Socié, Edouard Forcade, Anne Huynh, Igor Wolfgang Blau, Arnon Nagler, Jaime Sanz, Simona Piemontese, Mohamad Mohty, Fabio Ciceri
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5192–5200.
https://doi.org/10.1182/bloodadvances.2024015582
Published: 2025
Journal Articles

Cost-effectiveness of upfront vs delayed allogeneic hematopoietic stem cell transplant for intermediate risk AML

Open Access
Abdulrahman Alhajahjeh, Kishan K. Patel, Nikolai A. Podoltsev, Tariq Kewan, Jessica M. Stempel, Lourdes Mendez, Stuart Seropian, Lohith Gowda, Scott F. Huntington, Maximilian Stahl, Amer M. Zeidan, George Goshua, Jan Philipp Bewersdorf
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5234–5246.
https://doi.org/10.1182/bloodadvances.2025016532
Published: 2025
Includes: Supplemental data
Journal Articles

Post-HCT gilteritinib outweighs conditioning in NPM1 m FLT 3 -ITD AML

Open Access
Clinical Trials & Observations
Aaron James Stonestrom, Maria R. Baer
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5190–5191.
https://doi.org/10.1182/bloodadvances.2025017434
Published: 2025
Journal Articles

Pilot study of an inpatient physical activity intervention for older adults treated intensively for acute myeloid leukemia

Open Access
Clinical Trials & Observations
Heidi D. Klepin, Janet A. Tooze, Walter J. Rejeski, Shannon Mihalko, Timothy S. Pardee, Leslie Ellis, Dianna Howard, Wendy Demark-Wahnefried, Bayard L. Powell, Stephen Kritchevsky
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5152–5163.
https://doi.org/10.1182/bloodadvances.2025016260
Published: 2025
Includes: Supplemental data
Journal Articles

Ethical considerations for hematologic precursor conditions

Open Access
Clinical Trials & Observations
Eric C. Blackstone, Lachelle D. Weeks, Amy E. DeZern, Gregory A. Abel
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5148–5151.
https://doi.org/10.1182/bloodadvances.2025017215
Published: 2025
Journal Articles

A Practical Tool for Predicting Outcomes in Essential Thrombocythemia: Triple A Risk Model and Beyond

Open Access
Ozge Sonmez, Esiyla Oyur, Ipek Yonal-Hindilerden, Fehmi Hindilerden, Mehmet Sönmez, Abdulkadir Karışmaz, Zeynep Atlı, Teoman Soysal, Ahmet Emre Eşkazan
Journal: Blood Advances
Blood Adv bloodadvances.2025017896.
https://doi.org/10.1182/bloodadvances.2025017896
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of transplant conditioning, NPM1 mutations, and measurable residual disease in FLT3-ITD acute myeloid leukemia

Open Access
Clinical Trials & Observations
Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander E. Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L. Uy, Edmund K. Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Caroline Chen, Nahla Hasabou, Matt Rosales, Jason E. Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood Advances
Blood Adv (2025) 9 (20): 5123–5133.
https://doi.org/10.1182/bloodadvances.2025016306
Published: 2025
Includes: Supplemental data