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Journal Articles

JAK2 p.R564 germ line variants associated with hereditary thrombocythemia and hematologic neoplasms

Clinical Trials & Observations
Brittany L. Stewart, Hetty E. Carraway, Adriana L. Alvarez, Harry Lesmana, John Molina, Zheng Jin Tu, David S. Bosler, Aaron Gerds, Babal Jha, Emilia Calvaresi, Joy Nakitandwe, Abhay Singh
Journal: Blood Advances
Blood Adv (2025) 9 (7): 1534–1543.
https://doi.org/10.1182/bloodadvances.2024013661
Published: 2025
Journal Articles

Psychiatric and substance use disorders predict poor outcomes in older veterans with acute myeloid leukemia

Michelle H. Lee, Jennifer La, Mary T. Brophy, Nhan V. Do, Camille V. Edwards, Clark DuMontier, Gabriela S. Hobbs, Nathanael R. Fillmore
Journal: Blood Advances
Blood Adv (2025) 9 (7): 1555–1558.
https://doi.org/10.1182/bloodadvances.2024014468
Published: 2025
Includes: Supplemental data
Journal Articles

Trial eligibility, treatment patterns, and outcome for venetoclax-based therapy in AML: a prospective cohort study

Clinical Trials & Observations
Ofir Wolach, Itai Levi, Boaz Nachmias, Sigal Tavor, Irina Amitai, Yishai Ofran, Chezi Ganzel, Tsila Zuckerman, Doaa Okasha, Ilana Hellmann, Tamar Tadmor, Najib Dally, Jonathan Canaani, Galia Stemer, Moshe Grunspan, Adi Jacob Berger, Neta Frankel, Jenia Berelovich, Alexandra Bleterman, Moran Barak, Raanan Cohen, Yakir Moshe
Journal: Blood Advances
Blood Adv (2025) 9 (7): 1544–1554.
https://doi.org/10.1182/bloodadvances.2024014014
Published: 2025
Includes: Supplemental data
Journal Articles

Germ line JAK2 variants and hereditary blood cancers

Joseph Cannova, Michael W. Drazer
Journal: Blood Advances
Blood Adv (2025) 9 (7): 1585–1586.
https://doi.org/10.1182/bloodadvances.2025015810
Published: 2025
Journal Articles

Dual ASXL1 and CSF3R mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation

Lucie Darmusey, Anna J. Bagley, Thai T. Nguyen, Hanqian L. Carlson, Hunter Blaylock, Shawn B. Shrestha, Amara Pang, Samantha Tauchmann, Sarah C. Taylor, Amy C. Foley, Katia E. Niño, Eric M. Pietras, Theodore P. Braun, Julia E. Maxson
Journal: Blood Advances
Blood Adv (2025) 9 (7): 1593–1607.
https://doi.org/10.1182/bloodadvances.2024014362
Published: 2025
Includes: Supplemental data
Journal Articles

Pretransplant MRD does not seem to affect survival in NPM1 -mutated AML undergoing allogeneic stem cell transplantation

Alessia Fraccaroli, Vindi Jurinovic, Klaus Hirschbühl, Elena Stauffer, Katrin Koch, Stephan Breitkopf, Sarah Haebe, Heidrun Drolle, Maja Rothenberg-Thurley, Annika Dufour, Klaus H. Metzeler, Karsten Spiekermann, Marcus Hentrich, Andreas Hausmann, Mareike Verbeek, Christoph Schmid, Tobias Herold, Johanna Tischer
Journal: Blood Advances
Blood Adv (2025) 9 (7): 1630–1641.
https://doi.org/10.1182/bloodadvances.2024014767
Published: 2025
Includes: Supplemental data
Journal Articles

Hematological phenotypes in GATA2 deficiency syndrome arise from aging maladaptation to proliferation and somatic events

Juncal Fernandez-Orth, Cansu Koyunlar, Julia Miriam Weiss, Emanuele Gioacchino, Hans W.J. de Looper, Geoffroy Andrieux, Mariette ter Borg, Joke Zink, Irene Gonzalez Menendez, Remco Hoogenboezem, Baris Ismail Yigit, Kirsten Gussinklo, Roger Mulet-Lazaro, Charlotte Wantzen, Sophie Pfeiffer, Christian Molnar, Eric Bindels, Sheila Bohler, Mathijs Arnoud Sanders, Leticia Quintanilla-Martinez, Marcin W Wlodarski, Melanie Boerries, Ivo P. Touw, Charlotte Niemeyer, Miriam Erlacher, Emma de Pater
Journal: Blood Advances
Blood Adv bloodadvances.2024015106.
https://doi.org/10.1182/bloodadvances.2024015106
Published: 2025
Includes: Supplemental data
Journal Articles

ALLG APML5: bioavailability and safety of oral arsenic trioxide assessed during consolidation therapy for APL

Clinical Trials & Observations
Harry J. Iland, John Reynolds, Alan V. Boddy, Hayley B. Schultz, Liane Khoo, Shaun Fleming, Steven W. Lane, Nicholas Weber, Robin Gasiorowski, Tasman Armytage, Rosemary Harrup, Anne-Marie Watson, Peter Tan, Robin Filshie, Fiona Kwok, William Stevenson, Sam Yuen, Ashley P. Ng, Leesa Rowley, Paula Marlton, Andrew H. Wei
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1476–1484.
https://doi.org/10.1182/bloodadvances.2024015397
Published: 2025
Includes: Supplemental data
Journal Articles

Elderberry wine and promyelocytic leukemia

Clinical Trials & Observations
Steven D. Gore
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1474–1475.
https://doi.org/10.1182/bloodadvances.2025015905
Published: 2025
Journal Articles

Imetelstat: drugging telomerase in transfusion-dependent low- and intermediate-1–risk MDS

Clinical Trials & Observations
Joseph Cannova, Rafael Madero-Marroquin, Olatoyosi Odenike
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1390–1391.
https://doi.org/10.1182/bloodadvances.2024013929
Published: 2025
Journal Articles

Socioeconomic, racial-ethnic, household, and infrastructural disparities of hematologic cancer outcomes in the United States

David J. Fei-Zhang, Erik Wu, Alexander V. Stanisic, Lifang Hou, Leonidas C. Platanias, Stephen M. Ansell, Marquita W. Lewis-Thames, Sherif M. Badawy, Jonas Paludo
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1463–1471.
https://doi.org/10.1182/bloodadvances.2024013956
Published: 2025
Includes: Supplemental data
Journal Articles

Thrombosis, major bleeding, and mortality in 1 079 myelofibrosis patients, a matched population-based study

Anneli Enblom Larsson, Henrik Renlund, Björn I Andreasson, Henrik Holmberg, Maria Liljeholm, Anders Själander
Journal: Blood Advances
Blood Adv bloodadvances.2025016247.
https://doi.org/10.1182/bloodadvances.2025016247
Published: 2025
Includes: Supplemental data
Journal Articles

Validation of the revised 2022 European LeukemiaNet risk stratification in adult patients with acute myeloid leukemia

Clinical Trials & Observations
Leo Ruhnke, Marius Bill, Sven Zukunft, Jan-Niklas Eckardt, Silvia Schäfer, Sebastian Stasik, Maher Hanoun, Thomas Schroeder, Lars Fransecky, Björn Steffen, Stefan W. Krause, Sebastian Scholl, Andreas Hochhaus, Tim Sauer, Sabrina Kraus, Kerstin Schäfer-Eckart, Martin Kaufmann, Edgar Jost, Tim Brümmendorf, Christoph Schliemann, Jan-Henrik Mikesch, Utz Krug, Mathias Hänel, Anke Morgner, Markus Schaich, Andreas Neubauer, Roland Repp, Dirk Niemann, Ruth Seggewiss-Bernhardt, Achim Meinhardt, Johannes Kullmer, Ulrich Kaiser, Wolfgang Blau, Alexander Kiani, Götz Ulrich Grigoleit, Aristoteles Giagounidis, Alexander A. Wurm, Heidi Altmann, Jan Moritz Middeke, Johannes Schetelig, Carsten Müller-Tidow, Friedrich Stölzel, Claudia D. Baldus, Uwe Platzbecker, Hubert Serve, Martin Bornhäuser, Christian Thiede, Christoph Röllig
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1392–1404.
https://doi.org/10.1182/bloodadvances.2024013304
Published: 2025
Includes: Supplemental data
Journal Articles

Evidence-based risk stratification of myeloid neoplasms harboring TP53 mutations

Mithun Vinod Shah, Kevin Hung, MBBS FRACP FRCPA, Anmol Baranwal, Monika M Kutyna, Aref Al-Kali, Carla Toop, Patricia T. Greipp, Anna L Brown, Syed Naseem Shah, Shreyas Khanna, Dariusz Ladon, Vedavyas Gannamani, Dong Chen, Kebede Begna, Zoe Price, Danielle Rud, Mark R Litzow, William J Hogan, Peter G Bardy, Talha Badar, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Arana-Yi, Hassan B Alkhateeb, Abhishek A. Mangaonkar, Daniel Thomas, Christopher N Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra K. Hiwase
Journal: Blood Advances
Blood Adv bloodadvances.2024015238.
https://doi.org/10.1182/bloodadvances.2024015238
Published: 2025
Includes: Supplemental data
Journal Articles

Anxiety and depression in patients with histiocytic neoplasms and their associated clinical features

Anne S. Reiner, Yesne Alici, Denise D. Correa, Dana Bossert, Allison M. Sigler, Deanna Fournier, Kathleen Brewer, Gaurav Goyal, Thomas M. Atkinson, Priya Marathe, Jun J. Mao, Katherine S. Panageas, Eli L. Diamond
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1376–1386.
https://doi.org/10.1182/bloodadvances.2024014850
Published: 2025
Includes: Supplemental data
Journal Articles

Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis

Emma L. Boertjes, Sanne Massaar, Annelieke Zeilemaker, Jolinda Konijnenburg, Melissa Rijken, François G. Kavelaars, Tim Grob, Jurjen Versluis, Bob Löwenberg, Peter J. M. Valk, Mathijs A. Sanders
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1344–1355.
https://doi.org/10.1182/bloodadvances.2024014698
Published: 2025
Includes: Supplemental data
Journal Articles

High pulmonary hypertension risk by echocardiogram shortens survival in polycythemia vera

Clinical Trials & Observations
Alexander J. Gazda, Di Pan, Katie Erdos, Ghaith Abu-Zeinah, Alexandra Racanelli, Evelyn M. Horn, Joseph M. Scandura
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1320–1329.
https://doi.org/10.1182/bloodadvances.2024013970
Published: 2025
Includes: Supplemental data
Journal Articles

Relationship between additional mutations at diagnosis and treatment response in patients with essential thrombocythemia

Carole Mosnier, Sarah Bellal, Laurane Cottin, Françoise Boyer, Sandrine Lemoine, Amélie Bachelot, Joris Argentin, Bertille Pawlicki, Marie-Christine Copin, Rébecca Jouanneau-Courville, Anaïs Malinge, Jérémie Riou, Mathilde Hunault-Berger, Valérie Ugo, Corentin Orvain, Damien Luque Paz
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1303–1311.
https://doi.org/10.1182/bloodadvances.2024014791
Published: 2025
Includes: Supplemental data
Journal Articles

G3BP1::CSF1R: a new and actionable gene fusion in acute megakaryoblastic leukemia

Xi Luo, Chi-Keung Cheng, Hoi-Yun Chan, Kam-Tong Leung, Chi-Kong Li, Nellie Yuk-Fei Chung, Herbert Augustus Pitts, Ke Tian, Yuet-Fong Kam, Margaret H.L. Ng
Journal: Blood Advances
Blood Adv (2025) 9 (6): 1286–1292.
https://doi.org/10.1182/bloodadvances.2024014354
Published: 2025
Includes: Supplemental data
Journal Articles

A pharmacokinetic and safety study of oral arsenic trioxide in patients with acute promyelocytic leukemia

Farhad Ravandi, Sravanti Rangaraju, Hagop M Kantarjian, Guillermo Garcia-Manero, Musa Yilmaz, Kristen Baker, Terence Hall, Joy Grabenstein, Pourab Roy, Beth Ann Zamboni, William Zamboni, Erica Warlick, Michael Kelly, David A Roth, Gabriel Ghiaur
Journal: Blood Advances
Blood Adv bloodadvances.2024015453.
https://doi.org/10.1182/bloodadvances.2024015453
Published: 2025
Includes: Supplemental data