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Journal Articles

Humanizing CAR T-cell therapy in B-ALL

Clinical Trials & Observations
Rawan Faramand, Lori Muffly
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1916–1917.
https://doi.org/10.1182/bloodadvances.2025015852
Published: 2025
Journal Articles

Sickle cell care and implementation science

Clinical Trials & Observations
Halima Bello-Manga, Allison A. King
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1859–1860.
https://doi.org/10.1182/bloodadvances.2025015851
Published: 2025
Journal Articles

Post transplant maintenance therapy with newly FDA-approved revumenib for high-risk KMT2Ar acute leukemia

Clinical Trials & Observations
Olayinka Okeleji, David McCall, Amber Gibson, Miriam B. Garcia, Cesar Nunez, Michael Roth, Jeremy Connors, Demetrios Petropoulos, Priti Tewari, Branko Cuglievan, Irtiza N. Sheikh
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1988–1990.
https://doi.org/10.1182/bloodadvances.2024015527
Published: 2025
Journal Articles

Long term follow-up of MRD guided treatment of Ibrutinib plus Venetoclax for Relapsed CLL: phase 2 VISION/HO141 trial

Clinical Trials & Observations
Carsten Utoft Niemann, Julie Dubois, Kazem Nasserinejad, Caspar da Cunha-Bang, Sabina Kersting, Lisbeth Enggaard, Gerrit-Jan Veldhuis, Rogier Mous, Clemens H.M. Mellink, Anne-Marie F. van der Kevie-Kersemaekers, Johan A. Dobber, Christian Bjørn Poulsen, Wida Razawy, Rene Hollestein, Henrik Frederiksen, Ann Janssens, Ida Schjødt, Ellen C. Dompeling, Juha Ranti, Christian Brieghel, Mattias Mattsson, Mar Bellido, Hoa T.T. Tran, Arnon P. Kater, Mark-David Levin
Journal: Blood Advances
Blood Adv bloodadvances.2024015180.
https://doi.org/10.1182/bloodadvances.2024015180
Published: 2025
Includes: Supplemental data
Journal Articles

Atezolizumab Consolidation in Patients with High Risk Diffuse Large B-cell Lymphoma in Complete Remission after R-CHOP

Clinical Trials & Observations
Marcel Nijland, Djamila E Issa, Johanna A. A. Bult, Dries Deeren, Gerjo A. Velders, Marten R. Nijziel, Yorick Sandberg, Vibeke KJ Vergote, Margriet Oosterveld, Rob Fijnheer, Rolf Brouwer, Rinske Boersma, Kalung Wu, Laurens Nieuwenhuizen, Joost SP Vermaat, Roel J.W. van Kampen, Wim E. Terpstra, Sylvia Snauwaert, Marjolein WM van der Poel, Eva de Jongh, Marc Durian, Leonie Strobbe, Aart Beeker, Alain PA Gadisseur, Roos Van Rijn, Otto J. Visser, Jeanette Doorduijn, Tjeerd J.F. Snijders, Matthijs H. Silbermann, Daphne de Jong, Martine E.D. Chamuleau, Rogier Mous, Mathilde Jalving, Heleen Visser-Wisselaar, Sonja Jansen van den Bergh, Gerben JC Zwezerijnen, Edwin Bremer, Mirian Brink, Arjan Diepstra, Dana A Chitu, Harry R. Koene, Josée M. Zijlstra
Journal: Blood Advances
Blood Adv bloodadvances.2024015226.
https://doi.org/10.1182/bloodadvances.2024015226
Published: 2025
Includes: Supplemental data
Journal Articles

Molecular inflammatory expression profiles associated with the frequency of pain in individuals with sickle cell disease

Clinical Trials & Observations
Lana Mucalo Katunaric, Shuang Jia, Ashima Singh, Mark F Roethle, Julie A. Panepinto, David Brousseau, Martin Hessner, Amanda M. Brandow
Journal: Blood Advances
Blood Adv bloodadvances.2024015085.
https://doi.org/10.1182/bloodadvances.2024015085
Published: 2025
Includes: Supplemental data
Journal Articles

Characterizing the heterogeneity of Castleman disease and oligocentric subtype: findings from the ACCELERATE registry

Clinical Trials & Observations
Sheila K. Pierson, Joshua D. Brandstadter, Drew A. Torigian, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Corey Casper, Amy Chadburn, Shanmuganathan Chandrakasan, Angela Dispenzieri, Alexander Fosså, Christian Hoffmann, Makoto Ide, Razelle Kurzrock, Sudipto Mukherjee, Sunita Nasta, José-Tomás Navarro, Ariela Noy, Eric Oksenhendler, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Matthew Streetly, Raymond S. M. Wong, Lu Zhang, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1952–1965.
https://doi.org/10.1182/bloodadvances.2024014391
Published: 2025
Includes: Supplemental data
Journal Articles

Distress and symptom burden in patients with monoclonal gammopathy of undetermined significance and smoldering myeloma

Clinical Trials & Observations
Elizabeth K. O’Donnell, Jennifer E. Carroll, Jaqueline Perry, Katherine Padgett, Benjamin Harris, Vidhi Patel, Omar Nadeem, Areej El-Jawahri, Irene M. Ghobrial, Catherine R. Marinac
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1984–1987.
https://doi.org/10.1182/bloodadvances.2024015575
Published: 2025
Includes: Supplemental data
Journal Articles

Acquired mutations in patients with relapsed/refractory CLL who progressed in the ALPINE study

Clinical Trials & Observations
Jennifer R. Brown, Jessica Li, Barbara F. Eichhorst, Nicole Lamanna, Susan M. O’Brien, Constantine S. Tam, Lugui Qiu, Ruiqi Huang, Yang Shi, Adam Idoine, Tommi Salmi, Aileen Cleary Cohen, Mazyar Shadman
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1918–1926.
https://doi.org/10.1182/bloodadvances.2024014206
Published: 2025
Includes: Supplemental data
Journal Articles

Phase 1 study of quercetin, a natural antioxidant for children and young adults with Fanconi anemia

Clinical Trials & Observations
Parinda A. Mehta, Adam Nelson, Sara Loveless, Adam Lane, Tsuyoshi Fukuda, Ashley Teusink-Cross, Deborah Elder, Denise Lagory, Erica Miller, Jose A. Cancelas, Jonathan Howell, Junfang Zhao, Kana Mizuno, Kasiani C. Myers, Kelly Lake, Kelly McIntosh, Kenneth D. R. Setchell, Nathan Luebbering, Stephanie Edwards, Tafadzwa Chihanga, Susanne I. Wells, Stella M. Davies
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1927–1939.
https://doi.org/10.1182/bloodadvances.2024015053
Published: 2025
Includes: Supplemental data
Journal Articles

Phase 1 study of CD19 CAR T-cell therapy harboring a fully human scFv in CAR-naïve adult patients with B-ALL

Clinical Trials & Observations
Jordan Gauthier, Emily C. Liang, Jennifer J. Huang, Erik L. Kimble, Alexandre V. Hirayama, Salvatore Fiorenza, Jenna M. Voutsinas, Qian (Vicky) Wu, Carla A. Jaeger-Ruckstuhl, Barbara S. Pender, Delaney R. Kirchmeier, Aiko Torkelson, Kristina Braathen, Ryan Basom, Mazyar Shadman, Noam E. Kopmar, Ryan D. Cassaday, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1861–1872.
https://doi.org/10.1182/bloodadvances.2024015314
Published: 2025
Includes: Supplemental data
Journal Articles

Final analysis of the phase 1b Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT)

Clinical Trials & Observations
Chong Chyn Chua, Sun Loo, Chun Yew Fong, Stephen B. Ting, Ing Soo Tiong, Shaun Fleming, Natasha S. Anstee, Adam Ivey, Michael Ashby, Tse-Chieh Teh, John Reynolds, Andrew W. Roberts, Andrew H. Wei
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1827–1835.
https://doi.org/10.1182/bloodadvances.2024014900
Published: 2025
Includes: Supplemental data
Journal Articles

Patient-reported improvements in paroxysmal nocturnal hemoglobinuria treated with iptacopan from 2 phase 3 studies

Clinical Trials & Observations
Antonio M. Risitano, Carlos de Castro, Bing Han, Austin Kulasekararaj, Jaroslaw P. Maciejewski, Phillip Scheinberg, Yasutaka Ueda, Susan Vallow, Georgina Bermann, Marion Dahlke, Rakesh Kumar, Régis Peffault de Latour
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1816–1826.
https://doi.org/10.1182/bloodadvances.2024014652
Published: 2025
Includes: Supplemental data
Journal Articles

C3 as a predictive and prognostic biomarker in adult hemophagocytic lymphohistiocytosis: a large cohort study in China

Clinical Trials & Observations
Xuemei Shu, Xinjie Gao, Yujun Dai, Yuxiang Wang, Yilin Liu, Dawei Wang, Tao Guo
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1836–1846.
https://doi.org/10.1182/bloodadvances.2024014715
Published: 2025
Includes: Supplemental data
Journal Articles

Hepatosplenic T-cell lymphoma in children and adolescents

Clinical Trials & Observations
Lindsay F. Schwartz, Kaitlin J. Devine, Ana C. Xavier
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1847–1858.
https://doi.org/10.1182/bloodadvances.2025015857
Published: 2025
Journal Articles

The Impact of CMV Reactivation on Mortality After Chimeric Antigen Receptor T-Cell Therapy

Clinical Trials & Observations
Eleftheria Kampouri, Patrick W Flaherty, Hu Xie, Mandeep K Sekhon, Clementine Chalal, Terry L Stevens-Ayers, Damian J Green, Jordan Gauthier, Mazyar Shadman, Ailyn C. Pérez-Osorio, Keith R Jerome, Wendy M Leisenring, Michael J Boeckh, Joshua A. Hill
Journal: Blood Advances
Blood Adv bloodadvances.2024015164.
https://doi.org/10.1182/bloodadvances.2024015164
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of clonal hematopoiesis on clinical outcomes to BCMA CAR-T in multiple myeloma

Clinical Trials & Observations
Joshua N Gustine, Andrew R. Branagan, Diana D. Cirstea, Farah Rexha, Ryan Han, Andrew J. Yee, Marcela V. Maus, Matthew J. Frigault, Noopur S. Raje
Journal: Blood Advances
Blood Adv bloodadvances.2025015981.
https://doi.org/10.1182/bloodadvances.2025015981
Published: 2025
Includes: Supplemental data
Journal Articles

Stroke prevention in Hispanic children with sickle cell anemia: the SACRED trial

Clinical Trials & Observations Global Advances
Rosa M. Nieves, Teresa Latham, Nicolle Marte, Melissa Berges, Luisanna M. Sánchez, Gabriela Urcuyo, Carla Florencio, Carla Gonzalez, Paola del Villar, Sheena Chen, Daniel Ramirez, Paula Reyes, Manuel Marinez, Euladys Matos, Neelum D. Jeste, Susan E. Stuber, William H. Schultz, Adam C. Lane, Rafael Mena, Russell E. Ware
Journal: Blood Advances
Blood Adv (2025) 9 (8): 1791–1800.
https://doi.org/10.1182/bloodadvances.2024014327
Published: 2025
Includes: Supplemental data
Journal Articles

Gene Therapy for Hemophilia B: Results From the Phase1/2 101HEMB 1/2 Studies

Clinical Trials & Observations
Steven W. Pipe, M.D., Allen Poma, Anita Rajasekhar, Tamara Everington, Serap Sankoh, Jack Allen, Jason Cataldo, Eric Crombez
Journal: Blood Advances
Blood Adv bloodadvances.2024015184.
https://doi.org/10.1182/bloodadvances.2024015184
Published: 2025
Journal Articles

Gut microbiota restoration with oral pooled fecal microbiotherapy after intensive chemotherapy: the phase Ib CIMON trial

Clinical Trials & Observations
Florent Malard, Sylvain Thepot, Thomas Cluzeau, Martin Carre, Delphine Lebon, Pierre Bories, Ollivier Legrand, Marianne Schwarz, Michael Loschi, Mathieu Meunier, Magalie Joris, Cyrielle Gasc, Juliette Jouve, Benoît Levast, Emilie Plantamura, Emmanuel Prestat, Antoine Sabourin, Beatrice Gaugler, Joel Dore, Christian Récher, Mohamad Mohty
Journal: Blood Advances
Blood Adv bloodadvances.2024015571.
https://doi.org/10.1182/bloodadvances.2024015571
Published: 2025
Includes: Supplemental data