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Robert A S Ariëns
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Journal Articles

Use of Affimer Technology for Inhibition of α2-antiplasmin and Enhancement of Fibrinolysis

Nikoletta Pechlivani, Basmah Alsayejh, Mansour Khalaf Almutairi, Katie Simmons, Thembaninkosi Gaule, Fladia Phoenix, Noppadol Kietsiriroje, Sreenivasan Ponnambalam, Cedric Duval, Robert A S Ariëns, Christian Tiede, Darren C. Tomlinson, Ramzi Ajjan
Journal: Blood Advances
Blood Adv bloodadvances.2024014235.
https://doi.org/10.1182/bloodadvances.2024014235
Published: 2024
Includes: Supplemental data
Journal Articles

Affimer reagents as tool molecules to modulate platelet GPVI-ligand interactions and specifically bind GPVI dimer

Rui-Gang Xu, Christian Tiede, Antonio N. Calabrese, Lih T. Cheah, Thomas L. Adams, Julia S. Gauer, Matthew S. Hindle, Beth A. Webb, Daisie M. Yates, Alexandre Slater, Cédric Duval, Khalid M. Naseem, Andrew B. Herr, Darren C. Tomlinson, Steve P. Watson, Robert A. S. Ariëns
Journal: Blood Advances
Blood Adv (2024) 8 (15): 3917–3928.
https://doi.org/10.1182/bloodadvances.2024012689
Published: 2024
Includes: Supplemental data
Journal Articles

Fibrinogen levels and clot properties identify patients who benefit from catheter-directed thrombolysis after DVT

Clinical Trials & Observations
Aaron F. J. Iding, Ghadir Alkarithi, Hugo ten Cate, Robert A. S. Ariëns, Arina J. ten Cate-Hoek
Journal: Blood Advances
Blood Adv (2024) 8 (11): 2924–2932.
https://doi.org/10.1182/bloodadvances.2023012493
Published: 2024
Includes: Supplemental data
Journal Articles

Fibrin protofibril packing and clot stability are enhanced by extended knob-hole interactions and catch-slip bonds

Nathan L. Asquith, Cédric Duval, Artem Zhmurov, Stephen R. Baker, Helen R. McPherson, Marco M. Domingues, Simon D. A. Connell, Valeri Barsegov, Robert A. S. Ariëns
Journal: Blood Advances
Blood Adv (2022) 6 (13): 4015–4027.
https://doi.org/10.1182/bloodadvances.2022006977
Published: 2022
Includes: Supplemental data
Journal Articles

High fibrinogen γ′ levels in patient plasma increase clot formation at arterial and venous shear

Fraser L. Macrae, Frauke Swieringa, Johan W. M. Heemskerk, Robert A. S. Ariëns
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3468–3477.
https://doi.org/10.1182/bloodadvances.2020003346
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Fibrin and D-dimer bind to monomeric GPVI

Marie-Blanche Onselaer, Alexander T. Hardy, Clare Wilson, Ximena Sanchez, Amir K. Babar, Jeanette L. C. Miller, Callum N. Watson, Stephanie K. Watson, Arkadiusz Bonna, Helen Philippou, Andrew B. Herr, Diego Mezzano, Robert A. S. Ariëns, Steve P. Watson
Journal: Blood Advances
Blood Adv (2017) 1 (19): 1495–1504.
https://doi.org/10.1182/bloodadvances.2017007732
Published: 2017
Includes: Supplemental data