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Alexandre V. Hirayama
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Journal Articles

Answering the “Doctor, can CAR-T therapy cause cancer?” question in clinic

Clinical Trials & Observations
Rahul Banerjee, Christina Poh, Alexandre V. Hirayama, Jordan Gauthier, Ryan D. Cassaday, Mazyar Shadman, Andrew J. Cowan, Brian G. Till, Damian J. Green, Hans-Peter Kiem, Ajay K. Gopal, David G. Maloney
Journal: Blood Advances
Blood Adv (2024) 8 (4): 895–898.
https://doi.org/10.1182/bloodadvances.2023012336
Published: 2024
Journal Articles

Timing of anti–PD-L1 antibody initiation affects efficacy/toxicity of CD19 CAR T-cell therapy for large B-cell lymphoma

Alexandre V. Hirayama, Erik L. Kimble, Jocelyn H. Wright, Salvatore Fiorenza, Jordan Gauthier, Jenna M. Voutsinas, Qian Wu, Cecilia C. S. Yeung, Nicolas Gazeau, Barbara S. Pender, Delaney R. Kirchmeier, Aiko Torkelson, Abigail N. Chutnik, Ryan D. Cassaday, Aude G. Chapuis, Damian J. Green, Hans-Peter Kiem, Filippo Milano, Mazyar Shadman, Brian G. Till, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood Advances
Blood Adv (2024) 8 (2): 453–467.
https://doi.org/10.1182/bloodadvances.2023011287
Published: 2024
Includes: Supplemental data
Journal Articles

Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory CLL

Clinical Trials & Observations
Emily C. Liang, Aya Albittar, Jennifer J. Huang, Alexandre V. Hirayama, Erik L. Kimble, Andrew J. Portuguese, Aude Chapuis, Mazyar Shadman, Brian G. Till, Ryan D. Cassaday, Filippo Milano, Hans-Peter Kiem, Stanley R. Riddell, Cameron J. Turtle, David G. Maloney, Jordan Gauthier
Journal: Blood Advances
Blood Adv (2023) 7 (22): 6990–7005.
https://doi.org/10.1182/bloodadvances.2023011399
Published: 2023
Includes: Supplemental data
Journal Articles

A novel polymer-conjugated human IL-15 improves efficacy of CD19-targeted CAR T-cell immunotherapy

Alexandre V. Hirayama, Cassie K. Chou, Takahiro Miyazaki, Rachel N. Steinmetz, Henna A. Di, Simon P. Fraessle, Jordan Gauthier, Salvatore Fiorenza, Reed M. Hawkins, Willem W. Overwijk, Stanley R. Riddell, Mario Q. Marcondes, Cameron J. Turtle
Journal: Blood Advances
Blood Adv (2023) 7 (11): 2479–2493.
https://doi.org/10.1182/bloodadvances.2022008697
Published: 2023
Includes: Supplemental data
Journal Articles

Severe cytokine release syndrome is associated with hematologic toxicity following CD19 CAR T-cell therapy

Clinical Trials & Observations
Krishna R. Juluri, Qian Vicky Wu, Jenna Voutsinas, Jue Hou, Alexandre V. Hirayama, Erin Mullane, Nancy Miles, David G. Maloney, Cameron J. Turtle, Merav Bar, Jordan Gauthier
Journal: Blood Advances
Blood Adv (2022) 6 (7): 2055–2068.
https://doi.org/10.1182/bloodadvances.2020004142
Published: 2022
Includes: Supplemental data
Journal Articles

Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy

Mazyar Shadman, Jordan Gauthier, Kevin A. Hay, Jenna M. Voutsinas, Filippo Milano, Ang Li, Alexandre V. Hirayama, Mohamed L. Sorror, Sindhu Cherian, Xueyan Chen, Ryan D. Cassaday, Brian G. Till, Ajay K. Gopal, Brenda M. Sandmaier, David G. Maloney, Cameron J. Turtle
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3062–3069.
https://doi.org/10.1182/bloodadvances.2019000593
Published: 2019