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Volume 2, Issue 9

May 8 2018

In this Issue

STIMULUS REPORT
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
ERRATUM

STIMULUS REPORT

CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML

Claire M. Lucas,Laura J. Scott,Natasha Carmell,Alison K. Holcroft,Robert K. Hills,Alan K. Burnett,Richard E. Clark

View Articletitled, CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML

Supplemental data

Profilin 1–mediated cytoskeletal rearrangements regulate integrin function in mouse platelets

Simon Stritt,Inga Birkholz,Sarah Beck,Simona Sorrentino,K. Tanuj Sapra,Julien Viaud,Johannes Heck,Frédérique Gaits-Iacovoni,Harald Schulze,Xiaoping Du,John H. Hartwig,Attila Braun,Markus Bender,Ohad Medalia,Bernhard Nieswandt

View Articletitled, Profilin 1–mediated cytoskeletal rearrangements regulate integrin function in mouse platelets

Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Randomized phase 2 trial of monthly vitamin D to prevent respiratory complications in children with sickle cell disease
Clinical Trials & Observations

Margaret T. Lee,Meyer Kattan,Ilene Fennoy,Stephen M. Arpadi,Rachel L. Miller,Serge Cremers,Donald J. McMahon,Jeri W. Nieves,Gary M. Brittenham

View Articletitled, Randomized phase 2 trial of monthly vitamin D to prevent respiratory complications in children with sickle cell disease

Supplemental data

Prognostic significance of bone marrow abnormalities in the appendicular skeleton of patients with multiple myeloma
Clinical Trials & Observations

Kosei Matsue,Hiroki Kobayashi,Yuya Matsue,Yoshiaki Abe,Kentaro Narita,Akihiro Kitadate,Masami Takeuchi

View Articletitled, Prognostic significance of bone marrow abnormalities in the appendicular skeleton of patients with multiple myeloma

Supplemental data

GENE THERAPY

Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy

Olivier Humbert,Frieda Chan,Yogendra S. Rajawat,Troy R. Torgerson,Christopher R. Burtner,Nicholas W. Hubbard,Daniel Humphrys,Zachary K. Norgaard,Patricia O’Donnell,Jennifer E. Adair,Grant D. Trobridge,Andrew M. Scharenberg,Peter J. Felsburg,David J. Rawlings,Hans-Peter Kiem

View Articletitled, Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy

Supplemental data

HEMATOPOIESIS AND STEM CELLS

Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia
Clinical Trials & Observations

Tatsuya Imi,Takamasa Katagiri,Kazuyoshi Hosomichi,Yoshitaka Zaimoku,Viet Hoang Nguyen,Noriharu Nakagawa,Atsushi Tajima,Tetsuichi Yoshizato,Seishi Ogawa,Shinji Nakao

View Articletitled, Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia

Supplemental data

THROMBOSIS AND HEMOSTASIS

Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability
Clinical Trials & Observations

Georgette L. Suidan,Pradeep K. Singh,Sunita Patel-Hett,Zu-Lin Chen,Dmitri Volfson,Hitomi Yamamoto-Imoto,Erin H. Norris,Robert D. Bell,Sidney Strickland

View Articletitled, Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability

Supplemental data

Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies

Nadine Müller-Calleja,Svenja Ritter,Anne Hollerbach,Tanja Falter,Karl J. Lackner,Wolfram Ruf

View Articletitled, Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies

Analysis of MCFD2- and LMAN1-deficient mice demonstrates distinct functions in vivo

Min Zhu,Chunlei Zheng,Wei Wei,Lesley Everett,David Ginsburg,Bin Zhang

View Articletitled, Analysis of MCFD2- and LMAN1-deficient mice demonstrates distinct functions in vivo

TRANSPLANTATION

Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants
Clinical Trials & Observations

Anita J. Kumar,Soyoung Kim,Michael T. Hemmer,Mukta Arora,Stephen R. Spellman,Joseph A. Pidala,Daniel R. Couriel,Amin M. Alousi,Mahmoud D. Aljurf,Jean-Yves Cahn,Mitchell S. Cairo,Corey S. Cutler,Shatha Farhan,Usama Gergis,Gregory A. Hale,Shahrukh K. Hashmi,Yoshihiro Inamoto,Rammurti T. Kamble,Mohamed A. Kharfan-Dabaja,Margaret L. MacMillan,David I. Marks,Hideki Nakasone,Maxim Norkin,Muna Qayed,Olle Ringden,Harry C. Schouten,Kirk R. Schultz,Melhem M. Solh,Takanori Teshima,Alvaro Urbano-Ispizua,Leo F. Verdonck,Robert Peter Gale,Betty K. Hamilton,Navneet S. Majhail,Alison W. Loren

View Articletitled, Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants

ERRATUM

Fanciullino R, Farnault L, Donnette M, et al. CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine. Blood Adv. 2018;2(5):462-469.

View Articletitled, Fanciullino R, Farnault L, Donnette M, et al. CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine. <em>Blood Adv</em>. 2018;2(5):462-469.

Cover Image

Cover Image

COVER FIGURE
Thrombus formation by cofactor-independent antiphospholipid antibody in Lrp8^−/− mice. See the article by Müller-Calleja et al.
Front Matter
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Table of Contents

STIMULUS REPORT

CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML

Profilin 1–mediated cytoskeletal rearrangements regulate integrin function in mouse platelets

CLINICAL TRIALS AND OBSERVATIONS

Randomized phase 2 trial of monthly vitamin D to prevent respiratory complications in children with sickle cell disease
Clinical Trials & Observations

Prognostic significance of bone marrow abnormalities in the appendicular skeleton of patients with multiple myeloma
Clinical Trials & Observations

GENE THERAPY

Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy

HEMATOPOIESIS AND STEM CELLS

Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia
Clinical Trials & Observations

THROMBOSIS AND HEMOSTASIS

Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability
Clinical Trials & Observations

Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies

Analysis of MCFD2- and LMAN1-deficient mice demonstrates distinct functions in vivo

TRANSPLANTATION

Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants
Clinical Trials & Observations

ERRATUM

Fanciullino R, Farnault L, Donnette M, et al. CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine. Blood Adv. 2018;2(5):462-469.

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ASH Publications

American Society of Hematology

Issue Archive

Table of Contents

STIMULUS REPORT

CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML

Profilin 1–mediated cytoskeletal rearrangements regulate integrin function in mouse platelets

CLINICAL TRIALS AND OBSERVATIONS

Randomized phase 2 trial of monthly vitamin D to prevent respiratory complications in children with sickle cell disease Clinical Trials & Observations

Prognostic significance of bone marrow abnormalities in the appendicular skeleton of patients with multiple myeloma Clinical Trials & Observations

GENE THERAPY

Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy

HEMATOPOIESIS AND STEM CELLS

Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia Clinical Trials & Observations

THROMBOSIS AND HEMOSTASIS

Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability Clinical Trials & Observations

Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies

Analysis of MCFD2- and LMAN1-deficient mice demonstrates distinct functions in vivo

TRANSPLANTATION

Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants Clinical Trials & Observations

ERRATUM

Fanciullino R, Farnault L, Donnette M, et al. CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine. Blood Adv. 2018;2(5):462-469.

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Randomized phase 2 trial of monthly vitamin D to prevent respiratory complications in children with sickle cell disease
Clinical Trials & Observations

Prognostic significance of bone marrow abnormalities in the appendicular skeleton of patients with multiple myeloma
Clinical Trials & Observations

Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia
Clinical Trials & Observations

Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability
Clinical Trials & Observations

Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants
Clinical Trials & Observations