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Issue Archive

Volume 1, Issue 23
October 24 2017
Issue Cover

Table of Contents

EXCEPTIONAL CASE REPORT

Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT
Clinical Trials & Observations
Angela R. Smith,Ioanna A. Rota,Stefano Maio,Michel J. Massaad,Troy C. Lund,Luigi D. Notarangelo,Georg A. Holländer,Bruce R. Blazar
View Articletitled, Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT

STIMULUS REPORT

Pregnancy-related venous thromboembolism and risk of occult cancer
Clinical Trials & Observations
Anette Tarp Hansen,Katalin Veres,Erzsébet Horváth-Puhó,Vera Ehrenstein,Paolo Prandoni,Henrik Toft Sørensen
View Articletitled, Pregnancy-related venous thromboembolism and risk of occult cancer

CLINICAL TRIALS AND OBSERVATIONS

Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma
Clinical Trials & Observations
Tineke Casneuf,Xu Steven Xu,Homer C. Adams, III,Amy E. Axel,Christopher Chiu,Imran Khan,Tahamtan Ahmadi,Xiaoyu Yan,Sagar Lonial,Torben Plesner,Henk M. Lokhorst,Niels W. C. J. van de Donk,Pamela L. Clemens,A. Kate Sasser
View Articletitled, Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma
Supplemental data

GENE THERAPY

Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors
Amine Meliani,Florence Boisgerault,Zachary Fitzpatrick,Solenne Marmier,Christian Leborgne,Fanny Collaud,Marcelo Simon Sola,Severine Charles,Giuseppe Ronzitti,Alban Vignaud,Laetitia van Wittenberghe,Beatrice Marolleau,Fabienne Jouen,Sisareuth Tan,Olivier Boyer,Olivier Christophe,Alain R. Brisson,Casey A. Maguire,Federico Mingozzi
View Articletitled, Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors
Supplemental data
Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent
Camille Lévy,Fouzia Amirache,Anais Girard-Gagnepain,Cecilia Frecha,Francisco J. Roman-Rodríguez,Ornellie Bernadin,Caroline Costa,Didier Nègre,Alejandra Gutierrez-Guerrero,Lenard S. Vranckx,Isabelle Clerc,Naomi Taylor,Lars Thielecke,Kerstin Cornils,Juan A. Bueren,Paula Rio,Rik Gijsbers,François-Loïc Cosset,Els Verhoeyen
View Articletitled, Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent
Supplemental data

HEALTH SERVICES AND OUTCOMES

Depression, quality of life, and medical resource utilization in sickle cell disease
Clinical Trials & Observations
Soheir S. Adam,Charlene M. Flahiff,Shital Kamble,Marilyn J. Telen,Shelby D. Reed,Laura M. De Castro
View Articletitled, Depression, quality of life, and medical resource utilization in sickle cell disease
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor
Yanling Xiao,Jara Palomero,Joanna Grabowska,Liqin Wang,Iris de Rink,Luuk van Helvert,Jannie Borst
View Articletitled, Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

HSC extrinsic sex-related and intrinsic autoimmune disease–related human B-cell variation is recapitulated in humanized mice
Chiara Borsotti,Nichole M. Danzl,Grace Nauman,Markus A. Hölzl,Clare French,Estefania Chavez,Mohsen Khosravi-Maharlooei,Salome Glauzy,Fabien R. Delmotte,Eric Meffre,David G. Savage,Sean R. Campbell,Robin Goland,Ellen Greenberg,Jing Bi,Prakash Satwani,Suxiao Yang,Joan Bathon,Robert Winchester,Megan Sykes
View Articletitled, HSC extrinsic sex-related and intrinsic autoimmune disease–related human B-cell variation is recapitulated in humanized mice
Supplemental data
Progressive multifocal leukoencephalopathy and hematologic malignancies: a single cancer center retrospective review
Clinical Trials & Observations
Elizabeth C. Neil,Lisa M. DeAngelis
View Articletitled, Progressive multifocal leukoencephalopathy and hematologic malignancies: a single cancer center retrospective review

MYELOID NEOPLASIA

Risk and timing of cardiovascular death among patients with myelodysplastic syndromes
Clinical Trials & Observations
Andrew M. Brunner,Traci M. Blonquist,Gabriela S. Hobbs,Philip C. Amrein,Donna S. Neuberg,David P. Steensma,Gregory A. Abel,Amir T. Fathi
View Articletitled, Risk and timing of cardiovascular death among patients with myelodysplastic syndromes
Supplemental data
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
Mia Eriksson,Pablo Peña-Martínez,Ramprasad Ramakrishnan,Marion Chapellier,Carl Högberg,Gabriella Glowacki,Christina Orsmark-Pietras,Talía Velasco-Hernández,Vladimir Lj Lazarević,Gunnar Juliusson,Jörg Cammenga,James C. Mulloy,Johan Richter,Thoas Fioretos,Benjamin L. Ebert,Marcus Järås
View Articletitled, Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
Supplemental data

PLATELETS AND THROMBOPOIESIS

Cyclosporine or steroids as an adjunct to plasma exchange in the treatment of immune-mediated thrombotic thrombocytopenic purpura
Clinical Trials & Observations
Spero R. Cataland,Peter J. Kourlas,Shangbin Yang,Susan Geyer,Leslie Witkoff,Haiwa Wu,Camila Masias,James N. George,Haifeng M. Wu
View Articletitled, Cyclosporine or steroids as an adjunct to plasma exchange in the treatment of immune-mediated thrombotic thrombocytopenic purpura

THROMBOSIS AND HEMOSTASIS

Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13
Shobhit Gogia,Anju Kelkar,Changjie Zhang,Kannayakanahalli M. Dayananda,Sriram Neelamegham
View Articletitled, Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13
Supplemental data

TRANSFUSION MEDICINE

Potential impact of complement regulator deficiencies on hemolytic reactions due to minor ABO-mismatched transfusions
Clinical Trials & Observations
Priyanka Pandey,Waseem Q. Anani,Jerome L. Gottschall,Gregory A. Denomme
View Articletitled, Potential impact of complement regulator deficiencies on hemolytic reactions due to minor ABO-mismatched transfusions

ERRATUM

Field JJ, Majerus E, Gordeuk VR, et al. Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease. Blood Adv. 2017;1(20):1645-1649.
View Articletitled, Field JJ, Majerus E, Gordeuk VR, et al. Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease. <em>Blood Adv.</em> 2017;1(20):1645-1649.
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Gene ontology network, generated by Biological Networks Gene Ontology analysis. Nodes represent gene sets, and edges represent mutual overlap. Thus, highly redundant gene sets are grouped together as clusters, highlighted by the black circles. See the article by Xiao et al.

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