1-20 of 34
zinc finger protein gli2
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Mebendazole Mediates Its Anti-Leukemic Effects By Proteasomal Degradation of GLI Transcription Factors Via Inhibition of HSP70/90-Chaperone Activity in Acute Myeloid Leukemia in a Preclinical and Clinical Setting

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Vanessa Thaden, Franziska Modemann, MD, Alexander Krispien, Franziska Brauneck, Jasmin Wellbrock, PhD, Walter Fiedler, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5050.
https://doi.org/10.1182/blood-2019-129973
Published: 2019
Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3972.
https://doi.org/10.1182/blood-2019-121847
Published: 2019
Journal Articles

Mebendazole Exerts Potent Anti-Leukemic Effects By Downregulating Protein Levels of Hedgehog Transcription Factors GLI1 and GLI2

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Alexander Krispien, Vanessa Thaden, Jasmin Wellbrock, PhD, Walter Fiedler, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5145.
https://doi.org/10.1182/blood-2018-99-118189
Published: 2018
Journal Articles

Predicting Drug Response and Novel Therapeutic Candidates Using Signatures of Molecular Alterations in Hematologic Malignancies

Guillaume Labilloy, MS, Eric O'Brien, BSc, Brett VanCauwenbergh, BSc, Luke Byerly, BSc, Mitali Basu, MSc, William Seibel, PhD, Erin H. Breese, MD PhD, John Peter Perentesis, MD, Mayur Sarangdhar, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2219.
https://doi.org/10.1182/blood-2018-99-119933
Published: 2018
Journal Articles

Therapeutic Targeting of GLI1 in Acute Myeloid Leukemia

Metis Hasipek, PhD, Sayer Al-Harbi, PhD, James G Phillips, PhD, Bartlomiej P. Przychodzen, MSc, Alek Nielsen, BS, Yihong Guan, PhD, Dale Grabowski, BS, Phillip J Maciejewski, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Babal K Jha, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2654.
https://doi.org/10.1182/blood.V130.Suppl_1.2654.2654
Published: 2017
Journal Articles

Drug-Insensitive CML Stem/Progenitor Cells Highly Express Key Regulators of the Hedgehog Pathway and Inhibition of the Hedgehog Pathway Enhances Their Response to TKI Treatment

Kelly A. Turner, BSc, Katharina Rothe, PhD, Adrian Woolfson, MD PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4236.
https://doi.org/10.1182/blood.V128.22.4236.4236
Published: 2016
Journal Articles

The GLI-Code As a Potential Therapeutic Target in Myeloid Neoplasms

Sayer Alharbi, PhD, Alek d Nielsen, B.S., Metis Hasipek, PhD, Bartlomiej P Przychodzen, MSc, James G Phillips, PhD, Jaroslaw P Maciejewski, MD PhD FACP, Babal Jha, PhD
Journal: Blood
Blood (2016) 128 (22): 1655.
https://doi.org/10.1182/blood.V128.22.1655.1655
Published: 2016
Journal Articles

Biomarker and Gene Profiling Analyses in Acute Myeloid Leukemia during Treatment with Hedgehog Signaling Inhibitor

Seiji Kakiuchi, MD, Yosuke Minami, MD PhD, Nobuaki Fukushima, MD, Hiroshi Matsuoka, MD PhD, Tomoki Naoe, MD PhD, Hironobu Minami, MD D.MDSci.
Journal: Blood
Blood (2015) 126 (23): 1263.
https://doi.org/10.1182/blood.V126.23.1263.1263
Published: 2015
Journal Articles

The Hedgehog Regulated Transcription Factor and Tumor Suppressor, Gli3, Regulates Hematopoietic Stem Cell Number, Self-Renewal and Differentiation

Parvesh Chaudhry, PhD, Mohan Singh, PhD, Amy R McManus, Aparna Jorapur, Stephen James Capone, BS, Giridharan Ramsingh, MD, Akil Merchant, MD
Journal: Blood
Blood (2015) 126 (23): 2381.
https://doi.org/10.1182/blood.V126.23.2381.2381
Published: 2015
Journal Articles

The Alternate Activation of Hedgehog Pathway, Either in CD138+ or in CD138-CD19+ Multiple Myeloma Primary Cells, Impacts on Disease Outcome

Marina Martello, PhD, Daniel Remondini, PhD, Enrica Borsi, PhD, Mauro Procacci, Barbara Santacroce, Annalisa Pezzi, PhD, Angela Flores Dico, Elena Zamagni, Paola Tacchetti, MD, Lucia Pantani, MD, Giulia Marzocchi, PhD, Giovanni Martinelli, MD PhD, Michele Cavo, Carolina Terragna, PhD
Journal: Blood
Blood (2015) 126 (23): 2961.
https://doi.org/10.1182/blood.V126.23.2961.2961
Published: 2015
Journal Articles

A Novel Mechanism of GLI2 Mediated Regulation of IgM Secretion in Waldenström Macroglobulinemia

David A. Jackson, Timothy D. Smith, MS, Nansalmaa Amarsaikhan, PhD, Ann Vrabel, Ezequiel Tolosa, PhD, Luciana L. Almada, PhD, Martin E. Fernandez-Zapico, MD, Sherine F. Elsawa, PhD
Journal: Blood
Blood (2014) 124 (21): 3006.
https://doi.org/10.1182/blood.V124.21.3006.3006
Published: 2014
Journal Articles

Aberrant Hedgehog Pathway Activity Marks Clinical MDS Progression and Accelerates Leukemic Transformation in Vivo

Lukasz P Gondek, MD PhD, Yiting Lim, PhD, Hideki Makishima, MD PhD, Qiuju Wang, MA, Jaroslaw P. Maciejewski, MD PhD FACP, Peter D Aplan, MD, Amy E. DeZern, MD MHS, William Matsui, MD
Journal: Blood
Blood (2014) 124 (21): 528.
https://doi.org/10.1182/blood.V124.21.528.528
Published: 2014
Journal Articles

Steap3 Is a Novel Candidate Gene for Regulating the RBC Blood Storage Lesion By Mitigating Peroxidation of Membrane Lipids in a Mouse Model

Karen S deWolski, Hayley R Waterman, Peter C Thomson, PhD, James D Gorham, MD PhD, Matthew S Ranson, Heather L Howie, PhD, Adam Munday, PhD, Jill M Johnsen, MD, James C. Zimring, MD PhD
Journal: Blood
Blood (2014) 124 (21): 760.
https://doi.org/10.1182/blood.V124.21.760.760
Published: 2014
Journal Articles

GLI2 Transcription Factor Modulates CD40 Ligand Expression In Bone Marrow Stromal Cells

Matthew S. Neil, BS, Joel R. Dennison, Martin E. Fernandez-Zapico, MD, Sherine F. Elsawa, PhD
Journal: Blood
Blood (2013) 122 (21): 4271.
https://doi.org/10.1182/blood.V122.21.4271.4271
Published: 2013
Journal Articles

GLI1 Inhibitor GANT61 Deregulates stat3 Phosphorylation In Chronic Lymphocytic Leukemia Cells

Cheng Wang, Kang Lu MM, Xin Wang
Journal: Blood
Blood (2013) 122 (21): 4935.
https://doi.org/10.1182/blood.V122.21.4935.4935
Published: 2013
Journal Articles

Transcriptional Regulation Of GLI1 , Potential New Therapeutic Target For Diffuse Large B-Cell Lymphoma

Nitin K Agarwal, PhD, Kranthi Kunkalla, MS, David H Hawke, PhD, Yadong Liu, MD, Changju Qu, MD PhD, Francisco Vega, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2513.
https://doi.org/10.1182/blood.V122.21.2513.2513
Published: 2013
Journal Articles

GLI Transcription Factors Modulate IgM Secretion In Waldenström Macroglobulinemia

Nansalmaa Amarsaikhan, PhD, Joel R. Dennison, Shannon K. Boi, BS, Matthew S. Neil, BS, Sherine F. Elsawa, PhD
Journal: Blood
Blood (2013) 122 (21): 1771.
https://doi.org/10.1182/blood.V122.21.1771.1771
Published: 2013
Journal Articles

Expression Of Hedgehog Pathway Mediator Gli2 Represents a Clinically Negative Prognostic Marker In Acute Myeloid Leukemia and Its Inhibitor GANT61 Exerts Anti-Leukemic Effects In Vitro

Jasmin Wellbrock, Ph.D., Julian M Koehler, Katharina Wagner, MD, Emily Latuske, M.Sc., Hauke Stamm, M.Sc., Eik Vettorazzi, M.Sc., Gabi Vohwinkel, M.Sc., Marianne Klokow, Roswitha Kuhling-Thees, Sonja Loges, MD, Ph.D, Michael Amling, MD, Carsten Bokemeyer, MD, Michael Heuser, MD, Juergen Krauter, MD, Walter Fiedler, MD
Journal: Blood
Blood (2013) 122 (21): 53.
https://doi.org/10.1182/blood.V122.21.53.53
Published: 2013
Journal Articles

Analysis of Wnt and Hedgehog Pathways Regulating Protein Kinases CK1 and CK2 in Acute Myeloid Leukemia Cells and Stem Cells: Correlation with the Expression of Wnt and Hedgehog Targets and Biological and Clinical Features.

Alessandra Brancalion, Laura Quotti Tubi, Sabrina Manni, Anna Cabrelle, Fortunato Zaffino, Carmela Gurrieri, Gianpietro Semenzato, Francesco Piazza
Journal: Blood
Blood (2012) 120 (21): 2501.
https://doi.org/10.1182/blood.V120.21.2501.2501
Published: 2012
Journal Articles

Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist,

Alice Y Shih, BS, Annelie Schairer, Ph.D., Christian L Barrett, Ph.D., Ifat Geron, MSc, Angela C Court Recart, BS, MS, Daniel Goff, BS, Sacha Prashad, Jerry Wu, PharmD, Qingfei Jiang, PhD, Jason Gotlib, MD, MS, Larisa Balaian, Ph.D., Mark D. Minden, MD, PhD, Heather Leu, BS, Russell Wall, BS, Wenxue Ma, M.D., Ph.D., Kamran Shazand, PhD, John D McPherson, PhD, Steven M. Kornblau, MD, Ida Deichaite, PhD, Minya Pu, PhD, Lei Bao, PhD, Giovanni Martinelli, MD, Tannishtha Reya, PhD, Sheldon R Morris, MD, MPH, Todd VanArsdale, PhD, Thomas J Hudson, MD, Karen Messer, PhD, Hanna Mikkola, MD, PhD, Wendy J. Levin, MD, MS, Kelly A Frazer, Ph.D., Anil Sadarangani, Ph.D., Catriona Jamieson, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3776.
https://doi.org/10.1182/blood.V118.21.3776.3776
Published: 2011