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Journal Articles

Vitamin K3 (menadione) Induces Cytotoxicity in Chronic Myeloid Leukemia Stem Cells By Upregulating DYRK2 through the Inhibition of SIAH2 Ubiquitin Ligase

Chun Shik Park, PhD, Ye Shen, PhD, Andrew H Lewis, BS, Koramit Suppipat, MD, Monica Puppi, Julie Tomolonis, Taylor J Chen, Paul Pang, Toni-Ann Mistretta, Leyuan Ma, Michael R Green, PhD, Rachel E. Rau, MD, H. Daniel Lacorazza, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4171.
https://doi.org/10.1182/blood.V130.Suppl_1.4171.4171
Published: 2017
Journal Articles

DYRK2 Inhibits the Self-Renewal of Leukemic Stem Cells in Chronic Myeloid Leukemia By Inducing Degradation of c-Myc Downstream of the Reprogramming Factor KLF4

Chun Shik Park, PhD, Ye Shen, BS, Koramit Suppipat, MD, Andrew Lewis, B.S., Julie Tomolonis, B.S., Monica Puppi, M.Sc., toni-Ann Mistretta, PhD, Leyuan Ma, Michael R Green, MD PhD, Daniel Lacorazza, PhD
Journal: Blood
Blood (2016) 128 (22): 1879.
https://doi.org/10.1182/blood.V128.22.1879.1879
Published: 2016
Journal Articles

Dual Targeting of NOXA/MCL-1 Synergistically Induces Cell Death in Mantle Cell Lymphoma (MCL) Cells

Elisabeth Höring, German Ott, MD, Christine Bayha, Kleih Markus, Matthias C. Voehringer, MD, Heiko van Der Kuip, Walter E. Aulitzky, MD
Journal: Blood
Blood (2015) 126 (23): 2757.
https://doi.org/10.1182/blood.V126.23.2757.2757
Published: 2015
Journal Articles

Inhibition of Siah2 Ubiquitin Ligase By Vitamin K3 Attenuates Hypoxia and Blocks K562-R Cells Resistance

Na Xu, Yajuan Xiao, Xuan Zhou, Lin Li, Fen Huang, Bing Xu, MD, Liu Xiaoli, MD
Journal: Blood
Blood (2014) 124 (21): 5214.
https://doi.org/10.1182/blood.V124.21.5214.5214
Published: 2014
Journal Articles

Cisplatin Fails To Stimulate Production Of Reactive Oxygen Species and Release Of Neutrophil Extracellular Traps By Human Neutrophils In Vitro

Leonardo Pasalic, MBBS, Campbell Heather, BSc, Shane Thomas, PhD, Vivien M Chen, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4714.
https://doi.org/10.1182/blood.V122.21.4714.4714
Published: 2013
Journal Articles

Vitamin K3 Is a Potential Ultraviolet Photosensitizer for Pathogen Reduction of Human Platelets and Plasma

Fei Xu, PhD, Jaroslav Vostal, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3434.
https://doi.org/10.1182/blood.V120.21.3434.3434
Published: 2012
Journal Articles

Induction of Oxidative Stress and Glutathione Depletion by ABT-737, a Novel Small Molecule Inhibitor of Bcl-2, Contributes to Cytotoxicity in Leukemia Cells.

Joya Chandra, PhD, Adrienne Howard, Kathleen Jensen, Ray Meyn, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 4336.
https://doi.org/10.1182/blood.V110.11.4336.4336
Published: 2007
Journal Articles

Vitamin K3 Selectively Induces Apoptosis in Acute Lymphoblastic Leukemia Cells with Constitutive Activation of IKKα/NF-kB Activation.

Ningxi Zhu, MD, PhD, Lubing Gu, MD, Harry W. Findley, PhD, Kuang-Yueh Chiang, MD, Muxiang Zhou, MD
Journal: Blood
Blood (2005) 106 (11): 859.
https://doi.org/10.1182/blood.V106.11.859.859
Published: 2005
Journal Articles

The Role of Reactive Oxygen Species in γ-Globin Gene Activation by Fetal Hemoglobin Inducers.

Cheng-Hui Hsiao, Wei Li, Tzu-Fang Lou, Edward Lee, Betty S. Pace
Journal: Blood
Blood (2004) 104 (11): 3753.
https://doi.org/10.1182/blood.V104.11.3753.3753
Published: 2004