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Journal Articles

The AHR: adaptive evolution or one-off?

Michael H. Kroll

Blood (2019) 134 (26): 2337–2338.

https://doi.org/10.1182/blood.2019003943

Published: 2019

Journal Articles

Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment

Marilena Ciciarello, PhD, Giulia Corradi, PhD, Sabina Sangaletti, PhD, Barbara Bassani, Giorgia Simonetti, PhD, Jayakumar Vadakekolathu, PhD, Giovanni Marconi, Giovanni Martinelli, MD, Mario Paolo Colombo, Sergio Rutella, MDPhDFRCPath, Michele Cavo, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 1212.

https://doi.org/10.1182/blood-2019-126512

Published: 2019

Journal Articles

Immunosuppressive Diversity of Umbilical Cord-Derived Mesenchymal Stromal Cells

Tokiko Nagamura-Inoue, MD PhD, Atsuko Takahashi, MT., Yuki Yamamoto, MT, Akiko Hori, Yuta Miharu, MT, Kazuo Ogami, MT, Miwako Narita, MD PhD, Fumitaka Nagamura, MD PhD, Arinobu Tojo, MD PhD

Blood (2019) 134 (Supplement_1): 3584.

https://doi.org/10.1182/blood-2019-128627

Published: 2019

Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 5193.

https://doi.org/10.1182/blood-2019-128348

Published: 2019

Journal Articles

Effects of Interferon-γ on Proliferation and Ability of Secretion of Human Amniotic Mesenchymal Stem Cells

Ya Gao, MD, Ying Xu, Weiru Li, Yintian Zhang, Baohong Ping, Qifa Liu, MD

Blood (2019) 134 (Supplement_1): 5012.

https://doi.org/10.1182/blood-2019-125500

Published: 2019

Journal Articles

Multiple Myeloma Cell-Derived Interleukin-32gamma Increases the Immunosuppressive Function of Macrophages By Promoting Indoleamine 2,3-Dioxygenase (IDO) Expression

Haimeng Yan, Donghua He, Xi Huang, MD, Zhang En Fan, He Huang, MD, Zhen Cai, MD PhD

Blood (2018) 132 (Supplement 1): 3179.

https://doi.org/10.1182/blood-2018-99-114316

Published: 2018

Journal Articles

A MAFB Associated Regulatory Network Distinguishes CMML from Other MDS/MPN Overlap Entities

Wencke Walter, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD, Manja Meggendorfer, PhD

Blood (2018) 132 (Supplement 1): 3890.

https://doi.org/10.1182/blood-2018-99-115838

Published: 2018

Journal Articles

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Marilena Ciciarello, PhD, Giulia Corradi, BS, Giorgia Simonetti, PhD, Giovanni Marconi, Sabina Sangaletti, PhD, Mario Paolo Colombo, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti

Blood (2018) 132 (Supplement 1): 2579.

https://doi.org/10.1182/blood-2018-99-112497

Published: 2018

Journal Articles

Quantitative Assessment of Indoleamine 2,3-Dioxygenase (IDO) Expression at Diagnosis Predicts Clinical Outcome in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation

Sarah Parisi, Simone Ragaini, Darina Ocadlikova, Mariangela Lecciso, Giovanni Marconi, Stefania Paolini, MD PhD, Cristina Papayannidis, Maria Chiara Abbenante, Chiara Sartor, Giovanni Martinelli, MD, Emanuela Ottaviani, Francesca Bonifazi, Michele Cavo, MD, Antonio Curti

Blood (2018) 132 (Supplement 1): 5261.

https://doi.org/10.1182/blood-2018-99-115908

Published: 2018

Journal Articles

Targeting Tryptophan Catabolic Kynurenine Pathway Enhances Anti-Tumor Immunity and Cytotoxicity in Multiple Myeloma

Arghya Ray, PhD, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2018) 132 (Supplement 1): 1930.

https://doi.org/10.1182/blood-2018-99-117827

Published: 2018

Journal Articles

IDO Pathway Analysis for Identifying Novel Biomarkers in Multiple Myeloma

Vladimir Petrovic, PhD, Jamie Wong, Cedric E. Dos Santos, PhD, Richard Smith, Dan Fitzpatrick, Robert Loberg, Ariel Avilion, PhD

Blood (2018) 132 (Supplement 1): 5572.

https://doi.org/10.1182/blood-2018-99-111392

Published: 2018

Journal Articles

Indoximod Combined with Standard Induction Chemotherapy Is Well Tolerated and Induces a High Rate of Complete Remission with MRD-Negativity in Patients with Newly Diagnosed AML: Results from a Phase 1 Trial

Ashkan Emadi, MD PhD, Vu H. Duong, MD, Jeremy Pantin, MD, Mohammad Imran, MD, Rima Koka, MD PhD, Zeba Singh, MBBS, Edward A. Sausville, MD PhD, Jennie Y. Law, MD, Seung Tae Lee, MD PhD, Huidong Shi, PhD, Ravindra Kolhe, MD PhD, Maria R. Baer, MD, Michael R. Loken, PhD, Eugene P. Kennedy, MD, Charles Link, MD, David H. Munn, MD

Blood (2018) 132 (Supplement 1): 332.

https://doi.org/10.1182/blood-2018-99-117433

Published: 2018

Journal Articles

Up-Regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-Cell Proliferation and Transforms T-Cells Towards a Tumor-Tolerating Phenotype

Rodrigo Jacamo, PhD, Nguyet-Minh Hoang, B.A., Ahmed Al Rawi, Charlie Ly, BS, Robin Parihar, MDPhD, Teresa McQueen, MS, Peter P. Ruvolo, PhD, Patrick Williams, MD PhD, Gheath Alatrash, DO, PhD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 2443.

https://doi.org/10.1182/blood.V130.Suppl_1.2443.2443

Published: 2017

Journal Articles

Impact of PD-L Ligands and Indoleamine 2,3-Dioxygenase on Prognosis and Survival of Diffuse Large B-Cell Lymphoma

Olga Novosad, PhD MD, Nataliia Svergun, PhD, Oksana Skachkova, PhD, Tetiana Skrypets, MD, Ian Pastushenko, MD, Tetiana Kadnikova, MD, Oleksandr Gorbach, PhD, Nataliia Khranovska, PhD, Irina Kryachok, Prof., PhD

Blood (2017) 130 (Supplement 1): 5146.

https://doi.org/10.1182/blood.V130.Suppl_1.5146.5146

Published: 2017

Journal Articles

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

Keli L. Hippen, PhD, Margaret L. MacMillan, MD, Amanda Lemire, BS, Asim Saha, PhD, Eric Hanse, Colin Lord, Ameeta Kelekar, PhD, Roddy S. O'Connor, PhD, James L. Riley, PhD, Carl H June, MD, Leslie Kean, MD PhD, Jeffrey S. Miller, MD, John E. Wagner, MD, David H. Munn, MD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 1229.

https://doi.org/10.1182/blood.V128.22.1229.1229

Published: 2016

Journal Articles

Host Interleukin 6 and Indoleamine 2,3 Dioxygenase Regulate Inflammation in the Brain during Graft Versus Host Disease

Ludovic Belle, PhD, Erin Koester, MS, Emily Hansen, PhD, Michael Lawlor, PhD, Cecilia Hillard, PhD, William R. Drobyski, MD

Blood (2016) 128 (22): 2145.

https://doi.org/10.1182/blood.V128.22.2145.2145

Published: 2016

Journal Articles

Indoleamine 2,3-Dioxygenase (IDO1) Levels and Activity Are Increased in Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) and Correlate with Molecular Response to Nilotinib Therapy

Sieghart Sopper, PhD, Satu Mustjoki, MD PhD, Gunther Gastl, Prof., Dr., Zlatko Trajanoski, Prof. Dr., Frank Giles, MD MB, Andreas Hochhaus, MD, Simon Geisler, Dietmar Fuchs, Prof. Dr., Dominik Wolf, MD, Jeroen J.W.M. Janssen, MD PhD

Blood (2016) 128 (22): 1912.

https://doi.org/10.1182/blood.V128.22.1912.1912

Published: 2016

Journal Articles

Installing FVIII-Specific Tolerance in Hemophilia Via Engagement of the Aryl Hydrocarbon Receptor By Tryptophan Derivatives

Davide Matino, Marco Gargaro, Giulia Scalisi, Antonella Turco, Francisco Javier Quintana, Paolo Puccetti, Alfonso Iorio, MD PhD, Francesca Fallarino

Blood (2016) 128 (22): 2563.

https://doi.org/10.1182/blood.V128.22.2563.2563

Published: 2016

Journal Articles

Chemotherapy-Dependent ATP Release from Leukemia Dying Cells Induces Indoleamine 2,3-Dioxygenase 1 in Dendritic Cells

Mariangela Lecciso, PhD, Darina Ocadlikova, PhD, Elena De Marchi, M.S., Elisa Orioli, Sabina Sangaletti, PhD, Sara Trabanelli, PhD, Camilla Jandus, MD PhD, Andrea Bontadini, Annarita Redavid, Pedro Romero, professor, Mario Paolo Colombo, M.S., Francesco Di Virgilio, Giovanni Martinelli, Michele Cavo, MD, Elena Adinolfi, Antonio Curti, MD PhD

Blood (2016) 128 (22): 3711.

https://doi.org/10.1182/blood.V128.22.3711.3711

Published: 2016

Journal Articles

Osteoclasts Promote Immune Suppressive Microenvironment in Multiple Myeloma: Therapeutic Implication

Gang An, MD PhD, Chirag Acharya, Xiaoyan Feng, MD, Kenneth Wen, Mike Zhong, BS, Li Zhang, Nikhil C Munshi, MD, Lugui Qiu, MD, Yu-Tzu Tai, PhD, Kenneth C. Anderson, MD

Blood (2016) 128 (22): 3303.

https://doi.org/10.1182/blood.V128.22.3303.3303

Published: 2016

NARROW

The AHR: adaptive evolution or one-off?

Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment

Immunosuppressive Diversity of Umbilical Cord-Derived Mesenchymal Stromal Cells

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Effects of Interferon-γ on Proliferation and Ability of Secretion of Human Amniotic Mesenchymal Stem Cells

Multiple Myeloma Cell-Derived Interleukin-32gamma Increases the Immunosuppressive Function of Macrophages By Promoting Indoleamine 2,3-Dioxygenase (IDO) Expression

A MAFB Associated Regulatory Network Distinguishes CMML from Other MDS/MPN Overlap Entities

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Quantitative Assessment of Indoleamine 2,3-Dioxygenase (IDO) Expression at Diagnosis Predicts Clinical Outcome in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation

Targeting Tryptophan Catabolic Kynurenine Pathway Enhances Anti-Tumor Immunity and Cytotoxicity in Multiple Myeloma

IDO Pathway Analysis for Identifying Novel Biomarkers in Multiple Myeloma

Indoximod Combined with Standard Induction Chemotherapy Is Well Tolerated and Induces a High Rate of Complete Remission with MRD-Negativity in Patients with Newly Diagnosed AML: Results from a Phase 1 Trial

Up-Regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-Cell Proliferation and Transforms T-Cells Towards a Tumor-Tolerating Phenotype

Impact of PD-L Ligands and Indoleamine 2,3-Dioxygenase on Prognosis and Survival of Diffuse Large B-Cell Lymphoma

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

Host Interleukin 6 and Indoleamine 2,3 Dioxygenase Regulate Inflammation in the Brain during Graft Versus Host Disease

Indoleamine 2,3-Dioxygenase (IDO1) Levels and Activity Are Increased in Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) and Correlate with Molecular Response to Nilotinib Therapy

Installing FVIII-Specific Tolerance in Hemophilia Via Engagement of the Aryl Hydrocarbon Receptor By Tryptophan Derivatives

Chemotherapy-Dependent ATP Release from Leukemia Dying Cells Induces Indoleamine 2,3-Dioxygenase 1 in Dendritic Cells

Osteoclasts Promote Immune Suppressive Microenvironment in Multiple Myeloma: Therapeutic Implication

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American Society of Hematology

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American Society of Hematology

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