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Journal Articles

Protein Phase Separation in Hematopoietic Stem Cell Aging

Laure Maneix, PhD, Polina Iakova, M.S., Shannon Moree, B.A., Melanie Sweeney, B.A., Nagaishwarya Moka, MD, Sarvari Venkata Yellapragada, MD, Andre Catic, MD PhD

Blood (2019) 134 (Supplement_1): 5003.

https://doi.org/10.1182/blood-2019-124092

Published: 2019

Journal Articles

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

Ipsita Pal, PhD, Yu Ri Kim, MD, Sohani Das Sharma, PhD, Prabhjot S. Mundi, MD, Andre M. Grilo, PhD, Luke E Berchowitz, PhD, Mingzhao Zhu, PhD, Hull G. Kenneth, PhD, Daniel Romo, PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD

Blood (2019) 134 (Supplement_1): 4067.

https://doi.org/10.1182/blood-2019-131816

Published: 2019

Journal Articles

Casein Kinase 1 Delta Is a Novel Regulator of mRNA Translation and Druggable Target in Aggressive Lymphomas

Ipsita Pal, PhD, Sohani Das Sharma, PhD, Andre M. Grilo, PhD, Prabhjot S. Mundi, MD, Luigi Scotto, PhD, Abdullah Mahmood Ali, PhD, Luke E Berchowitz, PhD, Siddhartha Mukherjee, MD PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD

Blood (2019) 134 (Supplement_1): 2864.

https://doi.org/10.1182/blood-2019-129528

Published: 2019

Journal Articles

Identification of Old HSCs with Preserved Self-Renewal and Long-Term Reconstitution Potential

Harold K. Elias, MD, Joseph Y. Shin, MD PhD, Mohamed A.E. Ali, MD PhD, Sohini Chakraborty, PhD, Caryn J. Ha, BA, Igor Dolgalev, PhD, Colin Konishi, BA, Isabel Beerman, PhD, Christopher Y. Park, MD PhD

Blood (2019) 134 (Supplement_1): 2479.

https://doi.org/10.1182/blood-2019-129508

Published: 2019

Journal Articles

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

Maria Zingariello, PhD, Vittorio Rosti, MD, Alessandro M. Vannucchi, MD, Paola Guglielmelli, MD PhD, Claudio Bardelli, PhD, Maria Mazzarini, Rosa Alba Rana, Giovanni Barosi, Anna Rita Rita Migliaccio, PhD

Blood (2019) 134 (Supplement_1): 4209.

https://doi.org/10.1182/blood-2019-123140

Published: 2019

Journal Articles

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Timothy M Chlon, PhD, Emily Stepanchick, Kwangmin Choi, PhD, Yi Zheng, PhD, Kathleen Hueneman, Ashley Davis, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 773.

https://doi.org/10.1182/blood-2019-127471

Published: 2019

Journal Articles

Global Gene Expression Analysis Reveals Genotoxic Effect of Nrf2 Pharmacological Inhibitor Brusatol in Myeloid Leukemia Cells- a Promising Novel Anticancer Agent

Raveen Stephen Stallon Illangeswaran, MSc, Sreeja Karathedath, PhD, Bharathi M Rajamani, Poonkuzhali Balasubramanian, MSc

Blood (2018) 132 (Supplement 1): 5150.

https://doi.org/10.1182/blood-2018-99-117829

Published: 2018

Journal Articles

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Simon Raffel, MD, Jenny Hansson, Mattia Falcone, Christoph Lutz, Oliver Bischel, MD, Anthony D Ho, Jeroen Krijgsveld, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 2780.

https://doi.org/10.1182/blood-2018-99-117046

Published: 2018

Journal Articles

Computational Identification of Tractable Drug-like Inhibitors of eIF4A1

Derek Essegian, BS, MS, Tyler A. Cunningham, BS, Jonathan H. Schatz, MD, Stephan Schurer, PhD

Blood (2018) 132 (Supplement 1): 5802.

https://doi.org/10.1182/blood-2018-99-116829

Published: 2018

Journal Articles

CD99 Regulates Normal and Malignant Stem Cell Function By Restricting Protein Translation

Stephen S. Chung, MD, Wenhuo Hu, PhD, Liang Guo, PhD, Lavanya Kannan, PhD, Ross L. Levine, MD, Christopher Y. Park, MD PhD

Blood (2017) 130 (Supplement 1): 3749.

https://doi.org/10.1182/blood.V130.Suppl_1.3749.3749

Published: 2017

Journal Articles

The Marine Natural Compound Elatol Is a Novel Protein Translation Inhibitor with Potent Activity Against Aggressive Non-Hodgkin Lymphomas

Tara Peters, BA, Joseph Tillotson, PhD, Sarah C Wilmore, BSc, Alison Yeomans, PhD, Graham Packham, PhD, Eli Chapman, PhD, Jonathan H. Schatz, MD, Lingxiao Li, PhD

Blood (2017) 130 (Supplement 1): 4112.

https://doi.org/10.1182/blood.V130.Suppl_1.4112.4112

Published: 2017

Journal Articles

m 6 a Regulates Differentiation State and mRNA Translation in Myeloid Leukemia

Ly P Vu, PhD, Brian F Pickering, PhD, Yuanming Cheng, PhD, Zaccara Sara, PhD, Diu Nguyen, PhD, Gerard Minuesa, PhD, Timothy Chou, BS, Arthur Chow, BS, Matthew MacKay, Christopher Famulare, MS, Minal Patel, BA, Francine Garret-Bakelman, MD PhD, Ari Melnick, MD, Martin Carroll, MD, Christopher Mason, PhD, Samie R. Jaffrey, MD PhD, Michael G. Kharas, PhD

Blood (2017) 130 (Supplement 1): 791.

https://doi.org/10.1182/blood.V130.Suppl_1.791.791

Published: 2017

Journal Articles

Systematic Analyses of Clinically Relevant Single Nucleotide Polymorphisms (SNPs) of NR3C1 in Patients from the Italian Registry of Diamond Blackfan Anemia

Jiawen Li, Mayte Suarez-Farinas, Stuart Scott, PhD, Lilian Varricchio, Carolyn F. Whitsett, MD, Ugo Ramenghi, MD, Irma Dianzani, Anna Rita Migliaccio, PhD

Blood (2017) 130 (Supplement 1): 2200.

https://doi.org/10.1182/blood.V130.Suppl_1.2200.2200

Published: 2017

Journal Articles

PTC299 Is a Novel DHODH Inhibitor That Modulates VEGFA mRNA Translation and Inhibits Proliferation of a Broad Range of Leukemia Cells

Liangxian Cao, MD, Arthur Branstrom, PhD, John Baird, PhD, Christopher Trotta, PhD, Joseph Colacino, PhD, Marianne T. Santaguida, BSc, PhD, Diane Heiser, PhD BA, Mark Ma, PhD, Kensuke Kojima, MD PhD, Stuart Peltz, PhD, Edward O'Mara, MD, Robert Spiegel, MD, Marla Weetall, PhD

Blood (2017) 130 (Supplement 1): 1371.

https://doi.org/10.1182/blood.V130.Suppl_1.1371.1371

Published: 2017

Journal Articles

Distinct Metabolic Properties of MDS Stem Cells Provide Novel Opportunities for Therapeutic Intervention

Brett M Stevens, PhD, Daniel A Pollyea, MD, Nabilah Khan, PhD, Craig T Jordan, PhD

Blood (2016) 128 (22): 4316.

https://doi.org/10.1182/blood.V128.22.4316.4316

Published: 2016

Journal Articles

Stable Silencing of RUNX1/ETO Induces Expression of a Shortened PU.1 Variant in t(8;21) Kasumi Cells

Matthias Eder, Caroline Schoenherr, Katharina Wohlan, Fabian Frömling, Denise Hilfiker-Kleiner, Arnold Ganser, MD, Michaela Scherr

Blood (2016) 128 (22): 2716.

https://doi.org/10.1182/blood.V128.22.2716.2716

Published: 2016

Journal Articles

Mutant nucleophosmin1 (NPM1) Links Protein Translation with Oncogenic Metabolism in Leukemia

Marisa Juntilla, MD PhD, Alina Garbuzov, B.S., Natalie Ortiz, Julia Eberhard, Caitlin Roake, B.S., Yi Yin, B. S., Josh Gruber, MD PhD, Steven Artandi, MD PhD

Blood (2016) 128 (22): 2727.

https://doi.org/10.1182/blood.V128.22.2727.2727

Published: 2016

Journal Articles

Ribosome Profiling Uncovers Selective mRNA Translation Associated with eIF2 Phosphorylation in Erythrocyte Progenitors

Paolini Nahuel, MSc, Moore Kat, MSc, di Summa Franca, BSc, Fokkema Ivo, MSc, Jansen Sjoert, MSc, 't Hoen Peter-Bram, PhD, Marieke Von Lindern, PhD

Blood (2016) 128 (22): 1197.

https://doi.org/10.1182/blood.V128.22.1197.1197

Published: 2016

Journal Articles

Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis

Xin Liu, PhD, Yuannyu Zhang, PhD, Min Ni, PhD, Hui Cao, M.S., Robert Signer, PhD, Dan Li, B.S., Zhimin Gu, PhD, Zeping Hu, PhD, Navdeep Chandel, Ralph DeBerardinis, MD PhD, Feng Zhou, PhD, Zhen Shao, PhD, Jian Xu, PhD

Blood (2016) 128 (22): 1038.

https://doi.org/10.1182/blood.V128.22.1038.1038

Published: 2016

Journal Articles

The RNA-Binding Protein Musashi 2 Is Upregulated in the Proliferative Fraction of CLL Clones, Particularly in U-CLL Patients, and Its Silencing Induces Programmed Cell Death

Florencia Palacios, PhD, Xiao J. Yan, MD PhD, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 3216.

https://doi.org/10.1182/blood.V128.22.3216.3216

Published: 2016

NARROW

Protein Phase Separation in Hematopoietic Stem Cell Aging

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

Casein Kinase 1 Delta Is a Novel Regulator of mRNA Translation and Druggable Target in Aggressive Lymphomas

Identification of Old HSCs with Preserved Self-Renewal and Long-Term Reconstitution Potential

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Global Gene Expression Analysis Reveals Genotoxic Effect of Nrf2 Pharmacological Inhibitor Brusatol in Myeloid Leukemia Cells- a Promising Novel Anticancer Agent

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Computational Identification of Tractable Drug-like Inhibitors of eIF4A1

CD99 Regulates Normal and Malignant Stem Cell Function By Restricting Protein Translation

The Marine Natural Compound Elatol Is a Novel Protein Translation Inhibitor with Potent Activity Against Aggressive Non-Hodgkin Lymphomas

m 6 a Regulates Differentiation State and mRNA Translation in Myeloid Leukemia

Systematic Analyses of Clinically Relevant Single Nucleotide Polymorphisms (SNPs) of NR3C1 in Patients from the Italian Registry of Diamond Blackfan Anemia

PTC299 Is a Novel DHODH Inhibitor That Modulates VEGFA mRNA Translation and Inhibits Proliferation of a Broad Range of Leukemia Cells

Distinct Metabolic Properties of MDS Stem Cells Provide Novel Opportunities for Therapeutic Intervention

Stable Silencing of RUNX1/ETO Induces Expression of a Shortened PU.1 Variant in t(8;21) Kasumi Cells

Mutant nucleophosmin1 (NPM1) Links Protein Translation with Oncogenic Metabolism in Leukemia

Ribosome Profiling Uncovers Selective mRNA Translation Associated with eIF2 Phosphorylation in Erythrocyte Progenitors

Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis

The RNA-Binding Protein Musashi 2 Is Upregulated in the Proliferative Fraction of CLL Clones, Particularly in U-CLL Patients, and Its Silencing Induces Programmed Cell Death

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American Society of Hematology

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ASH Publications

American Society of Hematology

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