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Journal Articles

RORA Is a Potential Prognostic Biomarker and Therapeutic Target for Patients with Acute Myeloid Leukemia

Christina A. Snider, BA, Kevin Fung, Francesca Gould, Vera Adema, PhD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, Hassan Awada, MD, Milo Co, Teodora Kuzmanovic, BA, Bhumika J. Patel, MD, Aaron T. Gerds, MD MS, Sudipto Mukherjee, MD PhD MPH, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Tomas Radivoyevitch, PhD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD, Mikkael A. Sekeres, MD MS, Anjali S. Advani, MD

Blood (2019) 134 (Supplement_1): 2696.

https://doi.org/10.1182/blood-2019-126311

Published: 2019

Journal Articles

Reduced Number and Function of Endothelial Progenitor Cells in Patients with Beta Thalassemia Major

Galia Spectre, Pinhas Stark, MD, Arza Steimatzky, MD, Pia Raanani, MD, Dorit Lev, PhD, Ran Kornowski, MD, Idit Pazgal, MD

Blood (2019) 134 (Supplement_1): 2247.

https://doi.org/10.1182/blood-2019-129851

Published: 2019

Journal Articles

Activating KRAS , NRAS , and BRAF Mutants Enhance Proteasome Capacity and Reduce Endoplasmic Reticulum Stress in Multiple Myeloma, Thereby Promoting Plasma Cell Survival and Proteasome Inhibitor Resistance

Fazal Shirazi, PhD, Richard J. Jones, PhD, Isere Kuiatse, PhD, Zuzana Berkova, PhD, Hua Wang, PhD, Hans C. Lee, MD, Samuel Hong, PhD, Ram Kumar Singh, PhD, Lawrence Robert Dick, PhD, Nibedita Chattopadhyay, PhD, Robert Z. Orlowski, MD PhD

Blood (2018) 132 (Supplement 1): 406.

https://doi.org/10.1182/blood-2018-99-117577

Published: 2018

Journal Articles

The Pharmacological Blockade of Phosphodiesterase IV Potentiates the Anti-Tumor Effects of Arsenic Trioxide (ATO) in Acute Myelogenous Leukemia Cells through Multiple Signaling Pathways

Laura Mazzera, PhD, Manuela Abeltino, PhD, Antonio Bonati, MD, Paolo Lunghi, PhD

Blood (2017) 130 (Supplement 1): 2520.

https://doi.org/10.1182/blood.V130.Suppl_1.2520.2520

Published: 2017

Journal Articles

CG '806, a First-in-Class Pan-FLT3/BTK Inhibitor, Exhibits Potent Growth Inhibition As a Single Agent and in Combination with a BET Bromodomain Inhibitor or a Bcl2 Inhibitor on Primary AML and CLL Patient Samples

Stephen E Kurtz, PhD, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Andrea Local, PhD, Hongying Zhang, MD, Stephen Howell, MD, William Rice, PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD

Blood (2017) 130 (Supplement 1): 4626.

https://doi.org/10.1182/blood.V130.Suppl_1.4626.4626

Published: 2017

Journal Articles

The Effect of 5-Azacitidine Treatment on the Biologic Characteristics of Bone Marrow Mesenchymal Stem Cells in Patients with Myelodysplastic Syndromes

Ioannis Liapis, Aristea Batsali, Anastasios Mitrakos, Elisavet Kouvidi, Athanasios Galanopoulos, MD PhD, Charalampos Pontikoglou, MD PhD, Emmanouil Kanavakis, Helen A. Papadaki, MD PhD

Blood (2017) 130 (Supplement 1): 4242.

https://doi.org/10.1182/blood.V130.Suppl_1.4242.4242

Published: 2017

Journal Articles

Targeting Autophagy As a Therapeutic Strategy in Acute Myeloid Leukemia

Houman Nourkeyhani, MD, Den Haese P Jason, M.Sc., Portwood Scott, M.Sc, M.B.A., Diana Hanekamp, M.Sc., Megan Johnson, B.Sc., Eunice S. Wang, MD

Blood (2016) 128 (22): 3950.

https://doi.org/10.1182/blood.V128.22.3950.3950

Published: 2016

Journal Articles

Identification of Targeted Therapies for Rare Adult Mature T-Cell Leukemia Using Functional Ex Vivo Screening of Primary Patient Samples

Uma Borate, MD, Brianna A. Norris, Pierrette Lo, MS, Cristina E. Tognon, Brian Junio, Jeffrey W. Tyner, Brian J. Druker, MD

Blood (2016) 128 (22): 4720.

https://doi.org/10.1182/blood.V128.22.4720.4720

Published: 2016

Journal Articles

Role of Lymphoid Blasts and Derived Microparticles in Thromboembolic Events during Acute Lymphoblastic Leukaemia: Study of Procoagulant Effect of Vincristine on Jurkat Acute Lymphoid Leukaemia Cell Line

Claire Pluchart, Gregory Guimard, Maud Colinart, MD, Gael Poitevin, Philippe Nguyen, MDPhD

Blood (2016) 128 (22): 1434.

https://doi.org/10.1182/blood.V128.22.1434.1434

Published: 2016

Journal Articles

Bone Marrow Derived Mesenchymal Stem Cells from Splenic Marginal Zone Lymphoma Patients Exhibit Altered Proliferative Potential and B Lymphocyte Immunomodulatory Properties

Athanasia Kalyva, PhD, Charalampos Pontikoglou, MD PhD, Christina Kalpadakis, MD PhD, Athina Trakaki, Nikitas Zorzos, Maria Velegraki, MD PhD, Grigorios Panteloglou, Kallliopi Alpantaki, MDPhD, Gerasimos A. Pangalis, MD PhD, Helen A Papadaki, MDPhD

Blood (2015) 126 (23): 2396.

https://doi.org/10.1182/blood.V126.23.2396.2396

Published: 2015

Journal Articles

Broad Activity of Apto-253 in AML and Other Hematologic Malignancies Correlates with KLF4 Expression Level

Stephen E. Kurtz, PhD, Daniel Bottomly, MS, Beth Wilmot, PhD, Shannon K. McWeeney, PhD, William Rice, PhD, Stephen B Howell, MD, Avanish Vellanki, Brian J. Druker, MD, Jeffrey W. Tyner, PhD

Blood (2015) 126 (23): 1358.

https://doi.org/10.1182/blood.V126.23.1358.1358

Published: 2015

Journal Articles

Whole-Exome Sequencing Identifies Germline IDH2 and IDH3 mutations That Predispose to Myeloid Neoplasms

Remco Molenaar, M.Sc., Srinivasa Reddy Sanikommu, MD, Bhumika J. Patel, Bartlomiej Przychodzen, MSc, Cornelis J van Noorden, PhD, Tomas Radivoyevitch, PhD, Hideki Makishima, MD PhD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, MD PhD

Blood (2015) 126 (23): 1405.

https://doi.org/10.1182/blood.V126.23.1405.1405

Published: 2015

Journal Articles

Glucocorticoid-Induced Proliferation and Lack of Differentation in Untreated Pediatric Acute Myeloid Leukemic Blasts

Kim Klein, MD MSc, Eric Haarman, MD PhD, Valerie De Haas, MD PhD, C. Michel Zwaan, MD PhD, Ursula Creutzig, MD, Gertjan JL Kaspers, MD PhD

Blood (2015) 126 (23): 4843.

https://doi.org/10.1182/blood.V126.23.4843.4843

Published: 2015

Journal Articles

Peg-PLGA-PLL Nanoparticles in Combination with Gambogic Acid for Reversing Multidrug Resistance of K562/A02 Cells to Daunorubicin

Peipei Xu, PhD, Ruju Wang, Jian Ouyang, MD, Bing Chen, MD

Blood (2015) 126 (23): 4844.

https://doi.org/10.1182/blood.V126.23.4844.4844

Published: 2015

Journal Articles

Identification of Effective Targeted Drug Combinations Using Functional Ex Vivo Screening of Primary Patient Specimens

Stephen E Kurtz, PhD, Elie Traer, MD PhD, Jakki Martinez, Andrew Park, Jake Wagner, Ravi Pandya, PhD, William Bolosky, PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD

Blood (2015) 126 (23): 865.

https://doi.org/10.1182/blood.V126.23.865.865

Published: 2015

Journal Articles

Proteolytic Targeting Chimeric Molecules (PROTACs) Specific for Bromodomain-Containing Protein (BRD) 4 Are Active Against Pre-Clinical Models of Multiple Myeloma

Xiaohui Zhang, MD, PhD, Jing Lu, PhD, Yimin Qian, PhD, Robert Z. Orlowski, PhD, MD

Blood (2015) 126 (23): 917.

https://doi.org/10.1182/blood.V126.23.917.917

Published: 2015

Journal Articles

Low Vitamin D Levels Are Associated with Inferior Survival Following Azacitidine Treatment in Patients with Myelodysplastic Syndrome

Aleksandar Radujkovic, MD, Paul Schnitzler, MD, Anthony D. Ho, MD, Peter Dreger, MD, Thomas Luft, MD PhD

Blood (2015) 126 (23): 1699.

https://doi.org/10.1182/blood.V126.23.1699.1699

Published: 2015

Journal Articles

Emerging Roles of Wisp-1 and SFRP4 in Proliferation and Differentiation Potential of Wharton's Jelly Mesenchymal Stem/Stromal Cells

Aristea Batsali, Charalampos Pontikoglou, Emmanuel Agrafiotis, Elisavet Kouvidi, Irene Mavroudi, Athina Damianaki, Maria-Christina Kastrinaki, Helen Papadaki

Blood (2014) 124 (21): 4375.

https://doi.org/10.1182/blood.V124.21.4375.4375

Published: 2014

Journal Articles

MLL Rearrangements in Childhood Acute Lymphoblastic Leukemia: Clinical and Genetic Features of a Distinct Disease Entity

Maria Ampatzidou, MD, Stephanos I. Papadhimitriou, MD PhD, Loizos Petrikkos, MD, Dimitrios Pavlidis, Konstantinos Tsitsikas, Vassilios Papadakis, MD PhD, George Paterakis, MD PhD, Sophia Polychronopoulou, MD PhD

Blood (2014) 124 (21): 5355.

https://doi.org/10.1182/blood.V124.21.5355.5355

Published: 2014

Journal Articles

Targeting Lon Protease Activity Promotes Growth Inhibition and Apoptosis in Acute Myeloid Leukemia Cell Lines

Serena De Matteis, BS, Silvia Carloni, BS, Roberta Napolitano, BS, Michele Zanoni, BS, Lara Gibellini, BS PhD, Alessandro Lucchesi, MD, Andrea Cossarizza, MD, Giovanni Martinelli, MD

Blood (2014) 124 (21): 5130.

https://doi.org/10.1182/blood.V124.21.5130.5130

Published: 2014

NARROW

RORA Is a Potential Prognostic Biomarker and Therapeutic Target for Patients with Acute Myeloid Leukemia

Reduced Number and Function of Endothelial Progenitor Cells in Patients with Beta Thalassemia Major

Activating KRAS , NRAS , and BRAF Mutants Enhance Proteasome Capacity and Reduce Endoplasmic Reticulum Stress in Multiple Myeloma, Thereby Promoting Plasma Cell Survival and Proteasome Inhibitor Resistance

The Pharmacological Blockade of Phosphodiesterase IV Potentiates the Anti-Tumor Effects of Arsenic Trioxide (ATO) in Acute Myelogenous Leukemia Cells through Multiple Signaling Pathways

CG '806, a First-in-Class Pan-FLT3/BTK Inhibitor, Exhibits Potent Growth Inhibition As a Single Agent and in Combination with a BET Bromodomain Inhibitor or a Bcl2 Inhibitor on Primary AML and CLL Patient Samples

The Effect of 5-Azacitidine Treatment on the Biologic Characteristics of Bone Marrow Mesenchymal Stem Cells in Patients with Myelodysplastic Syndromes

Targeting Autophagy As a Therapeutic Strategy in Acute Myeloid Leukemia

Identification of Targeted Therapies for Rare Adult Mature T-Cell Leukemia Using Functional Ex Vivo Screening of Primary Patient Samples

Role of Lymphoid Blasts and Derived Microparticles in Thromboembolic Events during Acute Lymphoblastic Leukaemia: Study of Procoagulant Effect of Vincristine on Jurkat Acute Lymphoid Leukaemia Cell Line

Bone Marrow Derived Mesenchymal Stem Cells from Splenic Marginal Zone Lymphoma Patients Exhibit Altered Proliferative Potential and B Lymphocyte Immunomodulatory Properties

Broad Activity of Apto-253 in AML and Other Hematologic Malignancies Correlates with KLF4 Expression Level

Whole-Exome Sequencing Identifies Germline IDH2 and IDH3 mutations That Predispose to Myeloid Neoplasms

Glucocorticoid-Induced Proliferation and Lack of Differentation in Untreated Pediatric Acute Myeloid Leukemic Blasts

Peg-PLGA-PLL Nanoparticles in Combination with Gambogic Acid for Reversing Multidrug Resistance of K562/A02 Cells to Daunorubicin

Identification of Effective Targeted Drug Combinations Using Functional Ex Vivo Screening of Primary Patient Specimens

Proteolytic Targeting Chimeric Molecules (PROTACs) Specific for Bromodomain-Containing Protein (BRD) 4 Are Active Against Pre-Clinical Models of Multiple Myeloma

Low Vitamin D Levels Are Associated with Inferior Survival Following Azacitidine Treatment in Patients with Myelodysplastic Syndrome

Emerging Roles of Wisp-1 and SFRP4 in Proliferation and Differentiation Potential of Wharton's Jelly Mesenchymal Stem/Stromal Cells

MLL Rearrangements in Childhood Acute Lymphoblastic Leukemia: Clinical and Genetic Features of a Distinct Disease Entity

Targeting Lon Protease Activity Promotes Growth Inhibition and Apoptosis in Acute Myeloid Leukemia Cell Lines

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American Society of Hematology

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ASH Publications

American Society of Hematology

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