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Journal Articles

First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma

Edward A. Stadtmauer, MD FACP, Adam D. Cohen, MD, Kristy Weber, MD, Simon F Lacey, PhD, Vanessa E. Gonzalez, J. Joseph Melenhorst, PhD, Joseph A Fraietta, PhD, Gabriela Plesa, MD, Joanne Shea, Tina Matlawski, RN, Amanda Cervini, RN, Patricia Mangan, CRNP, Avery Gaymon, Stephanie Desjardins, Eric Lancaster, MD, January Salas-Mckee, Megan M. Suhoski, PhD, Andrew Fesnak, MD, Matthew O'Rourke, Anne Lamontagne, Don L. Siegel, MD PhD, Regina M Young, PhD, Anne Chew, PhD, Christopher L Nobles, PhD, Frederic D. Bushman, PhD, Howard Y. Chang, MD PhD, Ansuman T. Satpathy, MD PhD, Yangbing Zhao, PhD MD, Wei-Ting Hwang, PhD, Elizabeth O. Hexner, MDMS, Carl H June, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 49.
https://doi.org/10.1182/blood-2019-122374
Published: 2019
Journal Articles

Open-Label Pilot Study of Genetically Engineered NY-ESO-1 Specific T Cells (GSK3377794) Alone or in Combination with Pembrolizumab in Relapsed and Refractory Multiple Myeloma

Taiga Nishihori, MD, Jonathan L. Kaufman, MD, James E. Hoffman, Kristin Blouch, Sunil Pandit, Emily Butler, Amit Jain, Yuehui Wu, M. Phillip DeYoung, Aisha N. Hasan, Aaron P. Rapoport
Journal: Blood
Blood (2019) 134 (Supplement_1): 3134.
https://doi.org/10.1182/blood-2019-128059
Published: 2019
Journal Articles

Structure and Function of ATP-Dependent Chromatin Remodeling Complexes in Human Cancer

Cigall Kadoch, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-48.
https://doi.org/10.1182/blood-2019-121033
Published: 2019
Journal Articles

The Efficacy and Toxicity of Blinatumomab in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia: Russian Multicenter Experience

Sergey N. Bondarenko, PhDMD, Alexey A Maschan, MD PhD Professor, Elena N. Parovichnikova, MD PhD, Tatiana V Shelekhova, Vadim A Doronin, MD, Elena N Bogatyreva, Kamil D Kaplanov, Natalia Miakova, MD PhD, Andrey N Sokolov, MD, Ivan S Moiseev, MD PhD, Elena I Darskaya, MDPhD, Irina V Samorodova, Anna G Smirnova, MD PhD, Olesya V Paina, MD PhD, Tatjana A Bykova, MD PhD, Bella I Ayubova, Aleksandr D Kulagin, MD PhD Professor, Ludmila S Zubarovskaya, MD PhD Professor, Axel R Zander, MD PhD Professor, Boris V Afanasyev, MD PhD Professor
Journal: Blood
Blood (2017) 130 (Supplement 1): 2604.
https://doi.org/10.1182/blood.V130.Suppl_1.2604.2604
Published: 2017
Journal Articles

Gene Editing of TRAC Locus Utilizing Megatal Nucleases Increases Expression of Transgenic TCRs Delivered Via Lentiviral Vector-Mediated Gene Transfer

Michael S Magee, PhD, Iulia Diaconu, PhD, Mark Pogson, PhD, Ankit Gupta, PhD, Amy Jensen-Smith, PhD, Brian Collette, BS, Andrew Chavkin, MS, Eli Pasackow, BS, Aaron Edwards, MS, Kevin M. Friedman, Alexander Astrakhan, PhD, Michael T Certo, PhD, Jordan Jarjour, PhD, Richard A. Morgan, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1906.
https://doi.org/10.1182/blood.V130.Suppl_1.1906.1906
Published: 2017
Journal Articles

Cytokine Release Syndrome and Tumor Responses in a First-in-Man Trial of a Novel Affinity-Enhanced TCR-Gene Transduced T Cell Transfer Targeting NY-ESO-1 Antigen

Shinichi Kageyama, Mikiya Ishihara, Shigehisa Kitano, Yoshihiro Miyahara, Hidefumi Kato, Hideyuki Mishima, Noboru Yamamoto, Hiroyoshi Hattori, Hiroaki Iwase, Takeru Funakoshi, Takashi Kojima, Naoki Inoue, Tomohide Kidokoro, Daisuke Tomura, Sachiko Okamoto, Hideto Chono, Ikuei Nukaya, Junichi Mineno, Hiroaki Ikeda, Takashi Watanabe, MDPhD, Hiroshi Shiku
Journal: Blood
Blood (2017) 130 (Supplement 1): 841.
https://doi.org/10.1182/blood.V130.Suppl_1.841.841
Published: 2017
Journal Articles

Artificial Antigen Presenting Cells Expand NY-ESO-1 Antigen-Specific CD8+ T Cells From Patients with Melanoma

Marcela V. Maus, MD, PhD, Isabelle Riviere, PhD, Oriana Borquez-Ojeda, Xiuyan Wang, PhD, Jianda Yuan, MD, Taha Merghoub, PhD, Jason Plotkin, Richard J. O’Reilly, MD, Jedd D Wolchok, MD, PhD, Michel Sadelain, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4309.
https://doi.org/10.1182/blood.V118.21.4309.4309
Published: 2011
Journal Articles

Broad Spectrum Tumor Antigen-Specific Cytotoxic T Lymphocytes (CTL) for Therapy of Hematological Malignancy.

Ulrike Gerdemann, MD, Anne S. Christin, MD, Conrad Russell Cruz, MD, Carlos A. Ramos, MD, Donald R. Shaffer, Stephen Gottschalk, MD, Helen E. Heslop, MD, Malcolm K. Brenner, MB, PhD, FRCP, FRCPath, Catherine M. Bollard, MD, FRACP, FRCPA, Cliona M. Rooney, PhD, Ann M. Leen, PhD
Journal: Blood
Blood (2009) 114 (22): 4083.
https://doi.org/10.1182/blood.V114.22.4083.4083
Published: 2009
Journal Articles

An Unusual Expression: The Tumour Antigen SSX2IP Is Preferentially Expressed on the Surface of Acute Myeloid Leukaemia Cells during Early Mitosis.

Frances A.K. Denniss, BA, Nicola R. Hardwick, B.Sc., M.Phil, Ghulam J. Mufti, DM, FRCPath, Barbara A. Guinn, B.Sc., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 4305.
https://doi.org/10.1182/blood.V108.11.4305.4305
Published: 2006
Journal Articles

Harvest of Autologous Peripheral Blood Stem Cells Using Ifosfamide/Etoposide Regimen Combined with Granulocyte Colony-Stimulating Factor.

Mitsuho Noguchi, MD, Haruko Tashiro, MD, Moritaka Goto, MD, PhD, Kazuo Kawasugi, MD, PhD, Naoki Shirafuji, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 5218.
https://doi.org/10.1182/blood.V104.11.5218.5218
Published: 2004