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Journal Articles

Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias

Daichi Inoue, MD PhD, Chew Guo-Liang, Bo Liu, PhD, Stanley C Lee, PhD, Brittany C Michel, Joey Pangallo, B.S., Andrew R D'Avino, Khrystyna North, Lillian E Bitner, BSc, Muran Xiao, Susumu Kobayashi, Akihide Yoshimi, MD PhD, Hana Cho, MSc, Sydney X Lu, MD PhD, Justin Taylor, MD, Cigall Kadoch, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 637.
https://doi.org/10.1182/blood-2019-124616
Published: 2019
Journal Articles

Mutational Landscape of Grey Zone Lymphoma

Clementine Sarkozy, MD, Stacy Hung, Katsuyoshi Takata, MD PhD, Elizabeth Chavez, BSc, Cg RT, Tomohiro Aoki, MD PhD, Gerben Duns, PhD, Graham W Slack, MD PhD, Adele Telenius, Tomoko Miyata-Takata, Elena Viganò, PhD, Thierry Jo Molina, MDPhD, Diane Damotte, MDPhD, Susana Ben-Neriah, BSc, Christiane Copie-Bergman, MD PhD, Camille Laurent, MD PhD, Anja Mottok, MD PhD, Gilles Salles, MD PhD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD, Alexandra Traverse-Glehen, MD PhD, Christian Steidl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 21.
https://doi.org/10.1182/blood-2019-127375
Published: 2019
Journal Articles

SWI/SNF Dysregulation through a Prion-like Domain Causes AML

Simone S Riedel, PhD, Alexandra Lenard, BS, Kevin Nestler, BS, Congcong Lu, PhD, Hongbo Xie, PhD, Benjamin A Garcia, PhD, Kathrin M. Bernt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2512.
https://doi.org/10.1182/blood-2019-129280
Published: 2019
Journal Articles

Structure and Function of ATP-Dependent Chromatin Remodeling Complexes in Human Cancer

Cigall Kadoch, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-48.
https://doi.org/10.1182/blood-2019-121033
Published: 2019
Journal Articles

Chromatin Architecture Modulation in B-Cell Acute Lymphoblastic Leukemia Carrying DUX4 Fusions

Yosuke Tanaka, MD, Masahito Kawazu, MD PhD, Satoshi Inoue, PhD, Shinya Kojima, Ueno Toshihide, PhD, Toshiaki Uno, Moe Tamura, Susumu Goyama, MD PhD, Toshio Kitamura, MD PhD, Shinichi Morishita, PhD, Hiroyuki Mano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1240.
https://doi.org/10.1182/blood-2019-125207
Published: 2019
Journal Articles

Recurrent Non-Coding Mutations in BCL7A May Have Significant Functional Consequence in Multiple Myeloma

Chandraditya Chakraborty, PhD, Eugenio Morelli, MD, María Linares, PhD, Kenneth C. Anderson, MD, Mehmet Kemal Samur, PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 857.
https://doi.org/10.1182/blood-2019-129155
Published: 2019
Journal Articles

ARID1A Is Critical for Maintaining Normal Hematopoiesis in Mice

Lin Han, MSc, Vikas Madan, PhD, Anand Mayakonda, Pushkar Dakle, Weoi Woon Teoh, Pavithra Shyamsunder, PhD, Hazimah Binte Mohd Nordin, Zeya Cao, Janani Sundaresan, Ienglam Lei, Zhong Wang, H. Phillip Koeffler, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3833.
https://doi.org/10.1182/blood-2018-99-117993
Published: 2018
Journal Articles

Whole Exome Analysis Reveals Key Genomic Differences between Sporadic and Endemic Pediatric Burkitt Lymphoma

Denice Mae Palmos, BS, Rikhia Chakraborty, PhD, Harshal Abhyankar, MS, Joy C. Jayaseelan, MS, Maria F. Cardenas, BS, Joyce Kambugu, MBChB, Jeff Otiti, MBChB, Fadhil Geriga, MBChB, Pietro Pala, MD, John Sekabira, MBChB, MMed, Peter Wasswa, MBChB, Joseph Ssenyondwa, MBChB, Jackson Orem, MBChB, MMed, PhD, David A. Wheeler, PhD, Joseph Lubega, MBChB, MPH, Carl E. Allen, MD PhD, Donald Williams Parsons, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4117.
https://doi.org/10.1182/blood-2018-99-110762
Published: 2018
Journal Articles

NSD2 Interacts with SMARCA2 and Regulates Expression of Oncogenes CCND1 and PRL3 in T(4;14) Multiple Myeloma

Jing Yuan Chooi, BSc, Zhigang Xie, PhD, Jayantha Gunaratne, PhD, Dennis Keppei, PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4479.
https://doi.org/10.1182/blood-2018-99-110671
Published: 2018
Journal Articles

Loss of KDM6A/UTX Accelerate the Development of Multiple Myeloma

Daphne Dupere-Richer, PhD, Jianping Li, MD, Sayantan Maji, PhD, Crissandra Pipe, LATG, Sharon Norton, MS, Teresa Ezponda, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1004.
https://doi.org/10.1182/blood-2018-99-113835
Published: 2018
Journal Articles

Epigenetic Regulation and Therapeutic Targeting in Myeloma

Jonathan D. Licht, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-37.
https://doi.org/10.1182/blood-2018-99-109522
Published: 2018
Journal Articles

Genome-Wide Association Study (GWAS) Identifies a Significant Acute Myeloid Leukemia (AML) Susceptibility Locus Near BICRA

Christopher J. Walker, PhD, Christopher C. Oakes, Luke K Genutis, BS, Brian Giacopelli, BS, Sandya Liyanarachchi, MS, Deedra Nicolet, MS, Ann-Kathrin Eisfeld, MD, Markus Scholz, PhD, Pamela Brock, MS, LGC, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, Marius Bill, MD PhD, Andrew J. Carroll, PhD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, Eunice S. Wang, MD, Dietger Niederwieser, MD, Richard M. Stone, MD, John C. Byrd, MD, Sebastian Schwind, MD, Albert de la Chapelle, MD PhD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 85.
https://doi.org/10.1182/blood-2018-99-115170
Published: 2018
Journal Articles

Whole-Genome Genomics Correlates of Response to Anti-PD1 Therapy in Relapsed/Refractory Natural Killer/T Cell Lymphoma

Jing Quan Lim, PhD, Tiffany Tang, MBBS, MRCP, Daryl Tan, MD, Yurike Laurensia, Burton Chia Kuan Hui, Bsc, Jabed Iqbal, MD, Dachuan Huang, PhD, Tammy Song, PhD, Cedric Chuan Young Ng, MSc, Huangming Hong, Rex Au-Yeung, Benjamin Mow, MD, Qichun Cai, MD, LM Poon, Yok-Lam Kwong, Jin-Xin BEI, PhD, Tongyu Lin, Soon Thye Lim, Choon Kiat Ong, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2915.
https://doi.org/10.1182/blood-2018-99-110900
Published: 2018
Journal Articles

Human Germline HLTF E259K Mutation Identified in Familial MDS Patients Accumulates DNA Damage through Impaired PCNA Polyubiquitination

Kensuke Takaoka, Masahito Kawazu, Junji Koya, Akihide Yoshimi, Yosuke Masamoto, MD PhD, Hiroaki Maki, Takashi Toya, Takashi Kobayashi, Yasuhito Nannya, MD PhD, Shunya Arai, MD PhD, Hironori Ueno, Kenshi Suzuki, Hironori Harada, Atsushi Manabe, Yasuhide Hayashi, Hiroyuki Mano, MDPhD, Mineo Kurokawa, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4238.
https://doi.org/10.1182/blood.V130.Suppl_1.4238.4238
Published: 2017
Journal Articles

CBFβ-SMMHC Inhibition Disrupts Enhancer Chromatin Dynamics and Represses MYC Transcriptional Program in Inv(16) Leukemia

John Anto Pulikkan, PhD, Mahesh Hegde, Houda Belaghzal, Anuradha Illendula, Jun Yu, Hafiz Ahmed, Kelsey O'Hagen, Jianhong Ou, Carsten Müller-Tidow, Scot A. Wolfe, Julie Zhu, Job Dekker, John H. Bushweller, Lucio H. Castilla
Journal: Blood
Blood (2017) 130 (Supplement 1): 784.
https://doi.org/10.1182/blood.V130.Suppl_1.784.784
Published: 2017
Journal Articles

Ultra Deep Whole Exome Sequencing of Classical Hodgkin Lymphoma (cHL) Reveals Novel Recurrent Somatic Mutations

Felicia Gomez, PhD, Kilannin Krysiak, PhD, Cody Ramirez, BS, Eric J. Duncavage, MD, Zachary Skidmore, MEng, Grace Triska, BS, Lee Trani, BA, Nancy L. Bartlett, MD, Amanda F. Cashen, MD, Neha Mehta-Shah, MD, Brad S Kahl, MD, Friederike Kreisel, MD, Malachi Griffith, PhD, Todd A. Fehniger, MDPhD, Obi Griffith
Journal: Blood
Blood (2017) 130 (Supplement 1): 2733.
https://doi.org/10.1182/blood.V130.Suppl_1.2733.2733
Published: 2017
Journal Articles

Epigenetic Plasticity in ATP-Dependent Chromatin Remodeling Complexes in Human Acute Myeloid Leukemia

Mayukh Biswas, MSc, Shankha Subhra Chatterjee, MSc, Liberalis Debraj Boila, MSc, Debasis Banerjee, MD, Amitava Sengupta, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3801.
https://doi.org/10.1182/blood.V130.Suppl_1.3801.3801
Published: 2017
Journal Articles

In Situ Capture of the Molecular Composition of Erythroid Transcriptional Enhancers

Jian Xu, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-17.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-17.SCI-17
Published: 2017
Journal Articles

EZH1/2, SWI/SNF, and MLL2 Dependent Heterochromatin Formation and Abnormal Transcriptome in Hematological Malignancies

Makoto Yamagishi, PhD, Dai Fujikawa, PhD, Makoto Hori, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Seiichiro Kobayashi, MD, PhD, Masako Iwanaga, MD PhD MPH, Atae Utsunomiya, MD, Seiji Okada, MD, PhD, Kunihiro Tsukasaki, MD PhD, Kensei Tobinai, MD PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1200.
https://doi.org/10.1182/blood.V130.Suppl_1.1200.1200
Published: 2017
Journal Articles

Weekly CyborD-DARA Is a Safe and Effective Upfront Treatment for Newly Diagnosed Multiple Myeloma. Preliminary Results of the Early Phase 16-Bcni-001/Ctrial-IE (ICORG) 16-02 Study

Cian McEllistrim, MD, Mary R Cahill, MD, Philip Murphy, PhD BPharm, Vitaliy Mykytiv, MD, John Quinn, Amanda Bray, Jessica Walsh, Elizabeth Lenihan, Tara Kenny, Grace Hirakata, Imelda Parker, Andres Hernando, Michael O'Dwyer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3163.
https://doi.org/10.1182/blood.V130.Suppl_1.3163.3163
Published: 2017