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Journal Articles

Enzymatically Inactive 5-Lipoxygenase Inhibits Wnt-Signaling Activation Induced by Leukemia Inducing Oncogenes.

Jessica Roos, Maria Heinßmann, Claudia Oancea, Thorsten Maier, Dieter Steinhilber, Hubert Serve, MD, Martin Ruthardt, MD
Journal: Blood
Blood (2012) 120 (21): 2424.
https://doi.org/10.1182/blood.V120.21.2424.2424
Published: 2012
Journal Articles

Targeting the 5-Lipoxygenase as a Novel Principle of Stem Cell Therapy In Acute Myeloid Leukemia

Jessica Roos, Astrid Fischer, Dieter Steinhilber, Hubert Serve, Oliver Ottmann, Thorsten Maier, Martin Ruthardt
Journal: Blood
Blood (2010) 116 (21): 1846.
https://doi.org/10.1182/blood.V116.21.1846.1846
Published: 2010
Journal Articles

The Interaction of Bortezomib with P-Gp, MRP-1 and BCRP Drug Transporters: Implications for Therapeutic Applications of Bortezomib in Advanced Multiple Myeloma and Other Neoplasias.

Melissa G Ooi, M.D., Robert O'Connor, Ph.D, Jana Jakubikova, Ph.D, Justine Meiller, Diploma, in, Biochemistry, Degre, Steffen Klippel, Ph.D, Jake Delmore, Efstathios Kastritis, M.D, Douglas McMillin, Ph.D, Martin Clynes, Ph.D, Paul Richardson, M.D., Constantine S. Mitsiades, M.D., Ph.D, Peter O'Gorman, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2009) 114 (22): 1729.
https://doi.org/10.1182/blood.V114.22.1729.1729
Published: 2009
Journal Articles

Ap-1 Family Members C-Jun, JunB and Fra-2 Mediate Apoptosis and Differentiation in AML through Activation of GADD45á and ADFP Following Non-Steroidal Anti-Inflammatory Drug Treatment.

Akos Czibere, MD, PhD, Raminder Singh, PhD, Ingmar Bruns, MD, PhD, Luiz Fernando Zerbini, PhD, Rainer Haas
Journal: Blood
Blood (2008) 112 (11): 1196.
https://doi.org/10.1182/blood.V112.11.1196.1196
Published: 2008
Journal Articles

Local and Systemic Induction of an Abundant CD4+CD25+ Regulatory T Cell Population by Non-Hodgkin’s Lymphoma.

S. Mittal, N.A. Marshall, L. Duncan, D.J. Culligan, R.N. Barker, M.A. Vickers
Journal: Blood
Blood (2007) 110 (11): 357.
https://doi.org/10.1182/blood.V110.11.357.357
Published: 2007
Journal Articles

Sulindac Sulfide Reverts the Activation of the WNT-Signaling and Aberrant Self Renewal Induced by the AML-Associated Fusion Proteins PML/RARα and PLZF/RARα.

Gunnar Steinert, Anita Seshire, PhD, Dieter Hoelzer, MD, PhD, Martin Ruthardt, MD, Elena Puccetti, PhD
Journal: Blood
Blood (2007) 110 (11): 878.
https://doi.org/10.1182/blood.V110.11.878.878
Published: 2007