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Journal Articles

Engineered Blood Vessels

Jeffrey Lawson, PhD MD

Blood (2017) 130 (Supplement 1): SCI-12.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-12.SCI-12

Published: 2017

Journal Articles

E-WE Thrombin (ProCase) Inhibits Thrombin Mediated TAFI Activation and Accelerates TPA-Induced Thrombolysis

Erik I Tucker, PhD, Brandon Markway, PhD, Michael Wallisch, PhD, Norah Green Verbout, PhD, Christina Lorentz, PhD, Marschelle Carris, Owen J.T. McCarty, PhD, Andras Gruber, MD

Blood (2016) 128 (22): 1390.

https://doi.org/10.1182/blood.V128.22.1390.1390

Published: 2016

Journal Articles

Lack of Substantial Antithrombotic Effect of Low Circulating Coagulation Factor VII Levels in a Baboon Model of Acute Vascular Graft Thrombosis

Michael Wallisch, PhD, Greisel Jennifer, BS, Erik I Tucker, PhD, Owen J.T. McCarty, PhD, Monica T Hinds, PhD, Sue Murray, Jeff Crosby, PhD, Brett P. Monia, PhD, Andras Gruber, MD

Blood (2014) 124 (21): 1485.

https://doi.org/10.1182/blood.V124.21.1485.1485

Published: 2014

Journal Articles

Rapid Interruption Of Occlusive Thrombus Formation By The Protein C Activator Enzyme EWE Thrombin (ProCase) In Primates

Erik I Tucker, PhD, Michael Wallisch, PhD, Philberta Y Leung, PhD, Andras Gruber, MD, Enrico Di Cera, MD, Norah G Verbout, PhD

Blood (2013) 122 (21): 202.

https://doi.org/10.1182/blood.V122.21.202.202

Published: 2013

Journal Articles

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Erik I. Tucker, PhD, Ulla M Marzec, MS, Philberta Y Leung, PhD, Stephen R Hanson, PhD, Prof., Norah G Verbout, PhD, Sawan Hurst, MS, Owen J.T. McCarty, PhD, David Gailani, MD, Andras Gruber, MD

Blood (2011) 118 (21): 1173.

https://doi.org/10.1182/blood.V118.21.1173.1173

Published: 2011

Journal Articles

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

Erik I. Tucker, Ulla M. Marzec, Tara C. White, Sawan Hurst, Sandra Rugonyi, Owen J. T. McCarty, David Gailani, András Gruber, Stephen R. Hanson

Blood (2009) 113 (4): 936–944.

https://doi.org/10.1182/blood-2008-06-163675

Published: 2009

Journal Articles

Moderate Pharmacological Platelet Count Reduction Limits Thrombus Formation without Hemostatic Impairment in Primates

Erik I Tucker, Ulla M Marzec, Sawan Hurst, András Gruber, MD, Stephen R Hanson, PhD

Blood (2008) 112 (11): 1033.

https://doi.org/10.1182/blood.V112.11.1033.1033

Published: 2008

Journal Articles

High Efficiency Retro- and Lentiviral Transduction of Blood Endothelial Outgrowth Cells

Marcus A. Stockschlaeder, MD, Olga Shardakova, MD, Boris Fehse, PhD, Rudiger E. Scharf, MD

Blood (2007) 110 (11): 3727.

https://doi.org/10.1182/blood.V110.11.3727.3727

Published: 2007

Journal Articles

Inhibition of Factor XI Decreases Thrombin Production and Prevents Vascular Occlusion in Experimental Thrombosis in Primates.

Erik I. Tucker, BS, Ulla M. Marzec, MS, Andras Gruber, MD, Stephen R. Hanson, PhD

Blood (2007) 110 (11): 763.

https://doi.org/10.1182/blood.V110.11.763.763

Published: 2007

Journal Articles

Heparin-PF4 Antibodies Are Frequent after Vascular Surgery, but Not a Frequent Cause of Graft Thrombosis or Thrombocytopenia.

Tamas Alexy, MD, PhD, Sony Tucker, MD, Soames Boyle, Leanne Rochanda, Douglas Hood, MD, Vincent L. Rowe, MD, Fred A. Weaver, MD, Howard A. Liebman, MD

Blood (2006) 108 (11): 1491.

https://doi.org/10.1182/blood.V108.11.1491.1491

Published: 2006

Journal Articles

Safe Interruption of Ongoing Thrombosis by the Protein C Activator Thrombin Analog, W215A/E217A; a Comparison to Enoxaparin in Primates.

Ulla M. Marzec, MS, Leslie Bush, MA, Erik Tucker, BS, Andras Gruber, MD, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2006) 108 (11): 909.

https://doi.org/10.1182/blood.V108.11.909.909

Published: 2006

Journal Articles

Subcutaneous Dosing of CRA-027483, a Small Molecule FVIIa Inhibitor, Prevents Arterial Thrombosis in a Baboon Model.

Ulla M. Marzec, Juthamas Sukbuntherng, Ph.D, Stacie A. Dalrymple, Ph.D, Wendy B. Young, Ph.D, Dange Vijaykumar, PhD, Peter R. Young, Ph.D, Stephen R. Hanson, PhD

Blood (2005) 106 (11): 1867.

https://doi.org/10.1182/blood.V106.11.1867.1867

Published: 2005

Journal Articles

Comparison of Enoxaparin to the Thrombin Variant Protein C Activator, W215A/E217A, in a Primate Model of Thrombosis.

Ulla M. Marzec, Leslie Bush, MA, Andras Gruber, MD, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2005) 106 (11): 1868.

https://doi.org/10.1182/blood.V106.11.1868.1868

Published: 2005

Journal Articles

Efficacy of the Direct Thrombin Inhibitor Ximelagatran in Maintaining Small-Diameter Vascular Graft Patency.

Steven P. Schmidt, PhD, Michelle Evancho-Chapman, BS, Amy Deeken, MD, Hans Van Giezen, PhD, Stefan C. Carlsson, MD/PhD

Blood (2005) 106 (11): 1871.

https://doi.org/10.1182/blood.V106.11.1871.1871

Published: 2005

Journal Articles

Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates

LA Harker, UM Marzec, P Hunt, AB Kelly, A Tomer, E Cheung, SR Hanson, RB Stead

Blood (1996) 88 (2): 511–521.

https://doi.org/10.1182/blood.V88.2.511.bloodjournal882511

Published: 1996

NARROW

Engineered Blood Vessels

E-WE Thrombin (ProCase) Inhibits Thrombin Mediated TAFI Activation and Accelerates TPA-Induced Thrombolysis

Lack of Substantial Antithrombotic Effect of Low Circulating Coagulation Factor VII Levels in a Baboon Model of Acute Vascular Graft Thrombosis

Rapid Interruption Of Occlusive Thrombus Formation By The Protein C Activator Enzyme EWE Thrombin (ProCase) In Primates

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

Moderate Pharmacological Platelet Count Reduction Limits Thrombus Formation without Hemostatic Impairment in Primates

High Efficiency Retro- and Lentiviral Transduction of Blood Endothelial Outgrowth Cells

Inhibition of Factor XI Decreases Thrombin Production and Prevents Vascular Occlusion in Experimental Thrombosis in Primates.

Heparin-PF4 Antibodies Are Frequent after Vascular Surgery, but Not a Frequent Cause of Graft Thrombosis or Thrombocytopenia.

Safe Interruption of Ongoing Thrombosis by the Protein C Activator Thrombin Analog, W215A/E217A; a Comparison to Enoxaparin in Primates.

Subcutaneous Dosing of CRA-027483, a Small Molecule FVIIa Inhibitor, Prevents Arterial Thrombosis in a Baboon Model.

Comparison of Enoxaparin to the Thrombin Variant Protein C Activator, W215A/E217A, in a Primate Model of Thrombosis.

Efficacy of the Direct Thrombin Inhibitor Ximelagatran in Maintaining Small-Diameter Vascular Graft Patency.

Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates

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American Society of Hematology

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American Society of Hematology

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