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Journal Articles

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Qiu-Sha Huang, Jing Xue, Chen-Cong Wang, Ya-Zhen Qin, Lan-Ping Xu, Kaiyan Liu, Xiao-Jun Huang, MD, Xiao-Hui Zhang

Blood (2019) 134 (Supplement_1): 218.

https://doi.org/10.1182/blood-2019-126384

Published: 2019

Journal Articles

GFI1-Dependent SGPP1 Repression Promotes Growth and Survival of Myeloma Cells

Daniela Nicoleta Petrusca, PhD, Evgeny Berdyshev, PhD, Colin D. Crean, BS, Judith L Anderson, BS, G. David Roodman, MD PhD

Blood (2019) 134 (Supplement_1): 4387.

https://doi.org/10.1182/blood-2019-131106

Published: 2019

Journal Articles

Palmitoylation of GNA13 Is Essential for Its Tumor Suppressor Function and Its Inhibition Confers Hypersensitivity of B-Cell Lymphoma to BCL2 Inhibitors

Zhizhou Xia, Xiuli Zhang, Ping Liu, MD PhD, Bo Jiao, PhD, Ruibao Ren, MD PhD

Blood (2019) 134 (Supplement_1): 3787.

https://doi.org/10.1182/blood-2019-126368

Published: 2019

Journal Articles

Role of Rhoa G17V in Cell Migration and Transformation in Angioimmunoblastic T-Cell Lymphoma

Teresa Palomero, PhD, Jose R. Cortes, PhD, Anisha R. Cooke, Laura Belver, PhD, Govind Bhagat, Adolfo A. Ferrando, MD PhD

Blood (2018) 132 (Supplement 1): 4122.

https://doi.org/10.1182/blood-2018-99-115005

Published: 2018

Journal Articles

Regulation of Mature Erythrocyte Proteasomal Machinery Under Hypoxia

Anren Song, PhD, Angelo D'Alessandro, PhD, Kaiqi Sun, PhD, Hong Liu, MD, Zhangzhe Peng, MD, Modupe Idowu, MD, Rodney Kellems, PhD, Harinder S. Juneja, MD, Yang Xia, MD PhD

Blood (2018) 132 (Supplement 1): 3616.

https://doi.org/10.1182/blood-2018-99-113050

Published: 2018

Journal Articles

The Gfi1-SphK1 Axis Regulates the Growth and Survival of Myeloma Cells

Daniela Nicoleta Petrusca, PhD, Evgeny Berdyshev, PhD, Patrick Mulcrone, PhD, Colin D. Crean, BS, Judith L Anderson, BS, Quanhong Sun, PhD, Deborah Lynn Galson, PhD, G. David Roodman, MD PhD

Blood (2018) 132 (Supplement 1): 5615.

https://doi.org/10.1182/blood-2018-99-119507

Published: 2018

Journal Articles

Sphingosine-1-Phosphate Receptor 3 (S1PR3) Promotes Myeloid Commitment of Human Hematopoietic and Leukemic Stem Cells

Stephanie Zhi-Juan Xie, PhD, Kerstin Kaufmann, PhD, Olga I. Gan, PhD, Elisa Laurenti, PhD, Stanley W.K. Ng, Qiang Liu, Melissa Kleinau, Joseph Jargostf, Gareth Holmes, Chiara Luberto, PhD, Lina M Obeid, MD, Yusuf A. Hannun, MD, Jean C.Y. Wang, MD PhD, Mark D. Minden, MD PhD, John E. Dick, PhD

Blood (2018) 132 (Supplement 1): 1329.

https://doi.org/10.1182/blood-2018-99-119128

Published: 2018

Journal Articles

Inhibition of the C5a-C5aR Axis By the L-Aptamer Aon-D21 As a New Strategy to Ameliorate Uncontrolled Migration/Motility of Hematopoietic Stem Cells - Potential Therapeutic Implications for Paroxysmal Nocturnal Hemoglobinuria

Kamila Bujko, MS, Sylwia Rzeszotek, PhD, Janina Ratajczak, MD PhD DSci, Kai Hoehlig, PhD, Axel Vater, PhD, Mariusz Z Ratajczak, MD PhD DSc

Blood (2017) 130 (Supplement 1): 1188.

https://doi.org/10.1182/blood.V130.Suppl_1.1188.1188

Published: 2017

Journal Articles

The Effect of Bioactive Phospholipids on Normal and Malignant Hematopoiesis—Modulation of Their Effects By Downregulating the Activities of Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS)

Ahmed Abdelbaset-Ismail, PhD, Magdalena Kucia, PhD DSci, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc

Blood (2017) 130 (Supplement 1): 3803.

https://doi.org/10.1182/blood.V130.Suppl_1.3803.3803

Published: 2017

Journal Articles

Sphingosine Kinase 2 (SphK2) Deficiency Does Not Lower but Instead Surprisingly Increases the Level of Sphingosine-1-Phosphate (S1P) in Peripheral Blood, Providing a Novel Strategy for Stimulating Hematopoietic Stem Cell Mobilization By Inhibiting SphK2 Activity

Mateusz Adamiak, PhD, Lakshman Chelvarajan, Webster Santos, PhD, Kevin R Lynch, PhD, Ahmed Abdel-Latif, MD PhD, Mariusz Z Ratajczak, MD PhD DSc

Blood (2017) 130 (Supplement 1): 4477.

https://doi.org/10.1182/blood.V130.Suppl_1.4477.4477

Published: 2017

Journal Articles

Sphingosine-1-Phosphate (S1P) Signaling through S1P Receptor 1 (S1PR1) in Macrophage Contributes to Pain in Sickle Cell Disease

Morayo G. Adebiyi, BS, Yujin Zhang, MD, Kaiqi Sun, BS, Xia Hu, MD, Shusuan Zhao, MD, Hongyu Wu, PhD, Jacob Couturier, PhD, Dorothy L. Lewis, PhD, Edgar T. Walters, PhD, Yang Xia, MD PhD

Blood (2016) 128 (22): 2476.

https://doi.org/10.1182/blood.V128.22.2476.2476

Published: 2016

Journal Articles

Sphingolipids Regulate Myeloid-Erythroid Fate Determination in Human Hematopoiesis

Stephanie Zhi-Juan Xie, PhD, Kerstin Kaufmann, Olga I Gan, PhD, Sasan Zandi, MD PhD, Naoya Takayama, John E. Dick, PhD

Blood (2016) 128 (22): 3865.

https://doi.org/10.1182/blood.V128.22.3865.3865

Published: 2016

Journal Articles

Gfi1 Transcription Factor Is a Pro-Survival Molecule in Multiple Myeloma Cells

Denise Toscani, PhD, Cheolkyu Park, PhD, Fengming Wang, DDS, PhD, Judith Anderson, Nicola Giuliani, MD, PhD, G. David Roodman, MD PhD, Daniela Nicoleta Petrusca, PhD

Blood (2016) 128 (22): 4422.

https://doi.org/10.1182/blood.V128.22.4422.4422

Published: 2016

Journal Articles

Acid Ceramidase Inhibition Impairs Tumor Progression in a Rat Model of LGL Leukemia

Su-Fern Tan, PhD, Xin Liu, MD PhD, Kathleen Broeg, B.S., Todd E. Fox, PhD, David J. Feith, PhD, Thomas P. Loughran, Jr., MD

Blood (2015) 126 (23): 1246.

https://doi.org/10.1182/blood.V126.23.1246.1246

Published: 2015

Journal Articles

FTY720 (Fingolimod) Targets the Sphingolipid Pathway and Induces Autophagy-Related Apoptosis in Human Natural Killer Large Granular Lymphocyte Leukemia

Francis Roland LeBlanc, B.S., Hong-Gang Wang, MD PhD, David J. Feith, PhD, Thomas P. Loughran, Jr., MD

Blood (2015) 126 (23): 1288.

https://doi.org/10.1182/blood.V126.23.1288.1288

Published: 2015

Journal Articles

Transient Ex Vivo Inhibition of Heme Oxygenase 1 (HO-1) in Hematopoietic Stem/Progenitor Cells (HSPCs) By Small-Molecule Inhibitors Enhances Their Migratory Responsiveness to Bone Marrow (BM)-Secreted Chemoattractants a Novel and Simple Strategy to Improve Homing of HSPCs

Mateusz Adamiak, MS, Joseph B Moore IV, PhD, John Zhao, BS, Ahmed Abdelbaset-Ismail, PhD, Marcin Wysoczynski, PhD, Mariusz Z Ratajczak, MD PhD

Blood (2015) 126 (23): 4272.

https://doi.org/10.1182/blood.V126.23.4272.4272

Published: 2015

Journal Articles

S1P Modulator FTY720 Targets Multiple Myeloma Cell Proliferation and Stromal Interactions Via CXCR4/CXCL12 and mTOR Pathways

Katia Beider, PhD, Evgenia Rosenberg, Hanna Bitner, Merav Leiba, MD, Maya Koren-Michowitz, MD, Michal Abraham, PhD, Shiri Klein, Hanna Wald, Avichai Shimoni, MD, Amnon Peled, PhD, Arnon Nagler, MD

Blood (2014) 124 (21): 4707.

https://doi.org/10.1182/blood.V124.21.4707.4707

Published: 2014

Journal Articles

Evidence for Induction of a Tumor-Metastasis-Receptive Microenvironment in Bone Marrow and Other Organs As an Unwanted and Underestimated Side Effect of Chemotherapy/Radiotherapy

Pranesh Gunjal, MS, Gabriela Schneider, PhD, Sham Kakar, PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD

Blood (2014) 124 (21): 2925.

https://doi.org/10.1182/blood.V124.21.2925.2925

Published: 2014

Journal Articles

Sphingosine 1-Phosphate (S1P)/S1P Receptor 1 Pathway Has an Essential Role for Sickle Cell Disease

Yujin Zhang, PhD, Shushan Zhao, MD, Hongyu Wu, MD, Xia Hu, MD, Renna Luo, MD, Nicholas Parchim, PhD, Rodney E Kellems, PhD, Yang Xia, MD PhD

Blood (2014) 124 (21): 4063.

https://doi.org/10.1182/blood.V124.21.4063.4063

Published: 2014

Journal Articles

Elevated Adenosine Signaling Via Adenosine A2B Receptor Induces Normal and Sickle Erythrocyte Sphingosine Kinase 1 Activity

Kaiqi Sun, BS, Yujin Zhang, PhD, Mikhail Bogdanov, PhD, William Dowhan, PhD, Modupe Idowu, MD, Harinder S. Juneja, MD, Michael R. Blackburn, PhD, Rodney E. Kellems, PhD, Yang Xia, MD PhD

Blood (2014) 124 (21): 4067.

https://doi.org/10.1182/blood.V124.21.4067.4067

Published: 2014

NARROW

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

GFI1-Dependent SGPP1 Repression Promotes Growth and Survival of Myeloma Cells

Palmitoylation of GNA13 Is Essential for Its Tumor Suppressor Function and Its Inhibition Confers Hypersensitivity of B-Cell Lymphoma to BCL2 Inhibitors

Role of Rhoa G17V in Cell Migration and Transformation in Angioimmunoblastic T-Cell Lymphoma

Regulation of Mature Erythrocyte Proteasomal Machinery Under Hypoxia

The Gfi1-SphK1 Axis Regulates the Growth and Survival of Myeloma Cells

Sphingosine-1-Phosphate Receptor 3 (S1PR3) Promotes Myeloid Commitment of Human Hematopoietic and Leukemic Stem Cells

Inhibition of the C5a-C5aR Axis By the L-Aptamer Aon-D21 As a New Strategy to Ameliorate Uncontrolled Migration/Motility of Hematopoietic Stem Cells - Potential Therapeutic Implications for Paroxysmal Nocturnal Hemoglobinuria

The Effect of Bioactive Phospholipids on Normal and Malignant Hematopoiesis—Modulation of Their Effects By Downregulating the Activities of Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS)

Sphingosine Kinase 2 (SphK2) Deficiency Does Not Lower but Instead Surprisingly Increases the Level of Sphingosine-1-Phosphate (S1P) in Peripheral Blood, Providing a Novel Strategy for Stimulating Hematopoietic Stem Cell Mobilization By Inhibiting SphK2 Activity

Sphingosine-1-Phosphate (S1P) Signaling through S1P Receptor 1 (S1PR1) in Macrophage Contributes to Pain in Sickle Cell Disease

Sphingolipids Regulate Myeloid-Erythroid Fate Determination in Human Hematopoiesis

Gfi1 Transcription Factor Is a Pro-Survival Molecule in Multiple Myeloma Cells

Acid Ceramidase Inhibition Impairs Tumor Progression in a Rat Model of LGL Leukemia

FTY720 (Fingolimod) Targets the Sphingolipid Pathway and Induces Autophagy-Related Apoptosis in Human Natural Killer Large Granular Lymphocyte Leukemia

Transient Ex Vivo Inhibition of Heme Oxygenase 1 (HO-1) in Hematopoietic Stem/Progenitor Cells (HSPCs) By Small-Molecule Inhibitors Enhances Their Migratory Responsiveness to Bone Marrow (BM)-Secreted Chemoattractants a Novel and Simple Strategy to Improve Homing of HSPCs

S1P Modulator FTY720 Targets Multiple Myeloma Cell Proliferation and Stromal Interactions Via CXCR4/CXCL12 and mTOR Pathways

Evidence for Induction of a Tumor-Metastasis-Receptive Microenvironment in Bone Marrow and Other Organs As an Unwanted and Underestimated Side Effect of Chemotherapy/Radiotherapy

Sphingosine 1-Phosphate (S1P)/S1P Receptor 1 Pathway Has an Essential Role for Sickle Cell Disease

Elevated Adenosine Signaling Via Adenosine A2B Receptor Induces Normal and Sickle Erythrocyte Sphingosine Kinase 1 Activity

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American Society of Hematology

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ASH Publications

American Society of Hematology

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