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Journal Articles

Fatty Acid Binding Protein FABP5: A Novel Therapeutic Target in Acute Myeloid Leukemia

Metis Hasipek, PhD, Yihong Guan, PhD, Dale Grabowski, BS, Jaroslaw P. Maciejewski, MD PhD, Hetty E. Carraway, MD MBA, Babal K. Jha, PhD

Blood (2019) 134 (Supplement_1): 2553.

https://doi.org/10.1182/blood-2019-130475

Published: 2019

Journal Articles

Endogenous Retinoid X Receptor Ligands Act As Tumor Suppressors in MLL-AF9 Mouse Leukemia

Orsola Di Martino, PhD, Margaret Y Ferris, MD PhD, Hadwiger Gayla, Haixia Niu, PhD, John S. Welch, MD PhD

Blood (2019) 134 (Supplement_1): 2677.

https://doi.org/10.1182/blood-2019-128869

Published: 2019

Journal Articles

Targeting Antagonists of Retinoic Acid Signaling in Acute Myeloid Leukemia

Metis Hasipek, PhD, Dale Grabowski, BS, Yihong Guan, James G Phillips, PhD, Jaroslaw P. Maciejewski, Hetty E. Carraway, MD MBA, Babal K. Jha

Blood (2018) 132 (Supplement 1): 4067.

https://doi.org/10.1182/blood-2018-99-118924

Published: 2018

Journal Articles

Combinatorial Use of Bexarotene Plus ATRA for the Treatment of Acute Myeloid Leukemia

Orsola Di Martino, PhD, Haixia Niu, PhD, John S. Welch, MD PhD

Blood (2017) 130 (Supplement 1): 1405.

https://doi.org/10.1182/blood.V130.Suppl_1.1405.1405

Published: 2017

Journal Articles

Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease

Govindarajan Thangavelu, PhD, Asim Saha, PhD, Kazutoshi Aoyama, MD PhD, Cameron McDonald-Hyman, BA, Yu-Chi Lee, MSc, Chrysothemis Brown, MBBS, PhD, Angela Panoskaltsis-Mortari, PhD, Mark J. Osborn, PhD, Roshantha A Chandraratna, PhD, Randolph Noelle, PhD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 4534.

https://doi.org/10.1182/blood.V128.22.4534.4534

Published: 2016

Journal Articles

Homozygous Mutations in PHRF1 and PPARG in a Patient with Congenital Neutropenia and Profound Monocytosis: Understanding the Pathway Beyond Monocyte Versus Granulocyte Cell-Fate Choice

Houra Loghmani-khouzani, PhD, Maksim Klimiankou, PhD, Siarhei Kandabarau, BS, Cornelia Zeidler, MD MPH, Karl Welte, Prof. Dr. MD, Julia Skokowa, Prof. Dr.

Blood (2015) 126 (23): 648.

https://doi.org/10.1182/blood.V126.23.648.648

Published: 2015

Journal Articles

Gene Expression and Transcription Factor (TF) Activation Profiling Identifies Suppression of Multiple Myeloma (MM) Cell Survival and Chemoresistance Pathways By Inhibition of XPO1/CRM1-Dependent Nuclear Export with Selinexor

Shaun Rosebeck, PhD, Mattina Alonge, MS, Jagoda Jasielec, Anoop Mayampurath, PhD, Samuel L. Volchenboum, MD PhD, Sharon Shacham, PhDMBA, Michael Kauffman, MD PhD, Andrzej Jakubowiak, MD PhD

Blood (2014) 124 (21): 3444.

https://doi.org/10.1182/blood.V124.21.3444.3444

Published: 2014

Journal Articles

Delineating the Nuclear Receptors Involved in Retinoid Responsiveness in CTCL Cells

Sebastian S. DeMarco, Lei Wang, JianMing Chen, Lance C. Bridges

Blood (2014) 124 (21): 5496.

https://doi.org/10.1182/blood.V124.21.5496.5496

Published: 2014

Journal Articles

TBLR1 fuses to retinoid acid receptor α in a variant t(3;17)(q26;q21) translocation of acute promyelocytic leukemia

Yirui Chen, Shouyun Li, Chunlin Zhou, Chengwen Li, Kun Ru, Qing Rao, Haiyan Xing, Zheng Tian, Kejing Tang, Yingchang Mi, Baohong Wang, Min Wang, Jianxiang Wang

Blood (2014) 124 (6): 936–945.

https://doi.org/10.1182/blood-2013-10-528596

Published: 2014

Includes: Supplemental data

Journal Articles

Response Of Rare Variants Of Cutaneous T Cell Lymphoma (CTCL) To Treatment With Bexarotene. A Prospective German DeCOG Trial

Blood (2013) 122 (21): 4379.

https://doi.org/10.1182/blood.V122.21.4379.4379

Published: 2013

Journal Articles

Oridonin Upregulates All- Trans Retinoic Acid Receptor Alpha and Induces Differentiation Of NB4 Cells Though NF-Kb Pathway

Hua Yan, Yang Cao, Wei Wei, Nan Zhang, Ying-Li Wu, Guo-Qiang Chen, Sr., PhD

Blood (2013) 122 (21): 2909.

https://doi.org/10.1182/blood.V122.21.2909.2909

Published: 2013

Journal Articles

High Content Screening Identifies Synthetic Lethality Of Retinoid Receptor Agonists In IKZF1 -Mutated BCR-ABL1 positive Acute Lymphoblastic Leukemia

Michelle Churchman, Ph.D., Jonathan Low, Ph.D., Debbie Payne-Turner, Shann-Ching Chen, PhD, Jing Ma, PhD, Mark J. Althoff, Faiyaz Notta, PhD, John E. Dick, PhD, Laura Janke, DVM, PhD, Rodney Kiplin Guy, Ph.D, Taosheng Chen, Ph.D., Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA

Blood (2013) 122 (21): 172.

https://doi.org/10.1182/blood.V122.21.172.172

Published: 2013

Journal Articles

The Vitamin D Receptor Gene and Disease Severity in Sickle Cell Anemia

E. Leila Jerome Clay, MD, Alison Motsinger-Reif, PhD, Janelle Hoskins, PhD, Lindsay Veit, MD, David A. Barrow, PhD, Ali Calikoglu, MD, Rupa Redding-Lallinger, MD

Blood (2011) 118 (21): 2122.

https://doi.org/10.1182/blood.V118.21.2122.2122

Published: 2011

Journal Articles

Low-Dose Bexarotene Alone or in Combination for the Treatment of Relapsed or Refractory Cutaneous T-Cell Lymphoma.

Brady Beltran, MD, Antonio Paredes, MD, Celia Moises, MD, Gadwin Sanchez, MD, Lubomir Sokol, MD, PhD, Jorge Castillo, MD

Blood (2009) 114 (22): 4790.

https://doi.org/10.1182/blood.V114.22.4790.4790

Published: 2009

Journal Articles

A High Prevalence of Obesity in Acute Promyelocytic Leukemia (APL): Is Obesity a Risk Factor for APL? Implication of Targeted Therapy to Control Obesity and APL Prevention.

Julianne Qualtieri, MD, Jason Tedesco, MD, Bipin N. Savani, MD, Gregory Ayers, Meera Kumar, John P. Greer, MD, David R. Head, MD, Nishitha Reddy, MD

Blood (2009) 114 (22): 3099.

https://doi.org/10.1182/blood.V114.22.3099.3099

Published: 2009

Journal Articles

A Phase II Trial of Bexarotene, a Retinoid X Receptor Agonist, in Non-M3 Acute Myeloid Leukemia

Donald E. Tsai, MD, PhD, Melissa Potuzak, BS, Anthony Mato, MD, Alison Wakoff Loren, MD, MS, David Porter, MD, Edward A. Stadtmauer, MD, Steven Goldstein, MD, Alexander Perl, MD, Cezary Swider, BS, Adam Bagg, MD, Emile Youssef, MD, PhD, Selina Luger, MD

Blood (2008) 112 (11): 4040.

https://doi.org/10.1182/blood.V112.11.4040.4040

Published: 2008

Journal Articles

Gene Expression Analysis of Bexarotene Differentiated Acute Myeloid Leukemias Identifies Known and Novel Gene Targets.

Patricia Vanessa Sanchez, PhD, Reid P Bissonnette, PhD, Donald E Tsai, MD, PhD, Martin Carroll, MD

Blood (2008) 112 (11): 1199.

https://doi.org/10.1182/blood.V112.11.1199.1199

Published: 2008

Journal Articles

Human Myeloma Cells Undergo Differentiation and Apoptosis upon Exposure of Rosiglitazone and All-Trans Retinoic Acid Via Apoptosis Signaling Pathway Modulation

Haiwen Huang, Wu Depei, Guanghua Chen, Weirong Chang, Anska Y.H. Leung, Raymond Liang, Howard C.H. Chow

Blood (2008) 112 (11): 5045.

https://doi.org/10.1182/blood.V112.11.5045.5045

Published: 2008

Journal Articles

Low-Dose Bexarotene and Phototherapy or Interferon Alfa-2a in the Treatment of Patients with Relapsed or Refractory Cutaneous T-Cell Lymphoma

Brady Beltran, MD, Antonio Paredes, MD, Celia Moises, MD, Gadwin Sanchez, MD, Luis Riva, MD, Fernando Hurtado, MD, Renzo Salas, MD, Jorge Castillo, MD

Blood (2008) 112 (11): 5010.

https://doi.org/10.1182/blood.V112.11.5010.5010

Published: 2008

Journal Articles

Synergistic Growth Inhibition by the Combination of Acyclic Retinoid Plus Vitamin K 2 in HL-60 Cells

Junichi Kitagawa, Senji Kasahara, Takeshi Hara, Nobuhiro Kanemura, Masahito Shimizu, Hisashi Tsurumi, MD, PhD, Hisataka Moriwaki

Blood (2008) 112 (11): 5027.

https://doi.org/10.1182/blood.V112.11.5027.5027

Published: 2008

NARROW

Fatty Acid Binding Protein FABP5: A Novel Therapeutic Target in Acute Myeloid Leukemia

Endogenous Retinoid X Receptor Ligands Act As Tumor Suppressors in MLL-AF9 Mouse Leukemia

Targeting Antagonists of Retinoic Acid Signaling in Acute Myeloid Leukemia

Combinatorial Use of Bexarotene Plus ATRA for the Treatment of Acute Myeloid Leukemia

Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease

Homozygous Mutations in PHRF1 and PPARG in a Patient with Congenital Neutropenia and Profound Monocytosis: Understanding the Pathway Beyond Monocyte Versus Granulocyte Cell-Fate Choice

Gene Expression and Transcription Factor (TF) Activation Profiling Identifies Suppression of Multiple Myeloma (MM) Cell Survival and Chemoresistance Pathways By Inhibition of XPO1/CRM1-Dependent Nuclear Export with Selinexor

Delineating the Nuclear Receptors Involved in Retinoid Responsiveness in CTCL Cells

TBLR1 fuses to retinoid acid receptor α in a variant t(3;17)(q26;q21) translocation of acute promyelocytic leukemia

Response Of Rare Variants Of Cutaneous T Cell Lymphoma (CTCL) To Treatment With Bexarotene. A Prospective German DeCOG Trial

Oridonin Upregulates All- Trans Retinoic Acid Receptor Alpha and Induces Differentiation Of NB4 Cells Though NF-Kb Pathway

High Content Screening Identifies Synthetic Lethality Of Retinoid Receptor Agonists In IKZF1 -Mutated BCR-ABL1 positive Acute Lymphoblastic Leukemia

The Vitamin D Receptor Gene and Disease Severity in Sickle Cell Anemia

Low-Dose Bexarotene Alone or in Combination for the Treatment of Relapsed or Refractory Cutaneous T-Cell Lymphoma.

A High Prevalence of Obesity in Acute Promyelocytic Leukemia (APL): Is Obesity a Risk Factor for APL? Implication of Targeted Therapy to Control Obesity and APL Prevention.

A Phase II Trial of Bexarotene, a Retinoid X Receptor Agonist, in Non-M3 Acute Myeloid Leukemia

Gene Expression Analysis of Bexarotene Differentiated Acute Myeloid Leukemias Identifies Known and Novel Gene Targets.

Human Myeloma Cells Undergo Differentiation and Apoptosis upon Exposure of Rosiglitazone and All-Trans Retinoic Acid Via Apoptosis Signaling Pathway Modulation

Low-Dose Bexarotene and Phototherapy or Interferon Alfa-2a in the Treatment of Patients with Relapsed or Refractory Cutaneous T-Cell Lymphoma

Synergistic Growth Inhibition by the Combination of Acyclic Retinoid Plus Vitamin K 2 in HL-60 Cells

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American Society of Hematology

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