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Journal Articles

Pomalidomide Reduces Bleeding and Alters Expression of Angiogenesis-Related Proteins in Patients with Hereditary Hemorrhagic Telangiectasia

Shadi Swaidani, MD PhD, Suman Kundu, MBA, Mohamed Samour, MBBS, Bernard Silver, MD, Joseph Parambil, MD, Sonia Thomas, DrPH, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 5761.

https://doi.org/10.1182/blood-2019-127344

Published: 2019

Journal Articles

Non Invasive Evaluation of Bone Marrow Activity in Patients with Sickle Cell Disease: Correlation with Disease Features, Genotype, Markers of Erythropoiesis, Iron Metabolism and Hydroxyurea Treatment

Ioannis Papassotiriou, PhD, Pagona Flevari, MD, Christos Poziopoulos, MD, Sofia Zaliou, PhD, Vasilis Tsaousis, PhD, Katerina Larissi, MD, Maria Dimopoulou, MD, Veroniki Komninaka, MD, Marianna Politou, MD, Evangelos Terpos, MD, Ersi Voskaridou

Blood (2019) 134 (Supplement_1): 4821.

https://doi.org/10.1182/blood-2019-121622

Published: 2019

Journal Articles

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Samit Ghosh, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2018) 132 (Supplement 1): 2392.

https://doi.org/10.1182/blood-2018-99-113451

Published: 2018

Journal Articles

Elevated AREG/EGF Ratio Prior to Transplantation Is Associated with Pre-Transplant Clostridium Difficile Infection, Unresolved Tissue Damage, and Poorer Overall Survival

Sarah L.P. Atkins, MD, Todd E. DeFor, MS, Margaret L. MacMillan, MD, Lucie Turcotte, MD, Armin Rashidi, MD PhD, Daniel J. Weisdorf, MD, Alexander Khoruts, MD, Shernan G. Holtan, MD

Blood (2018) 132 (Supplement 1): 3353.

https://doi.org/10.1182/blood-2018-99-115686

Published: 2018

Journal Articles

Rapid MRD-Negative Responses in Patients with Relapsed/Refractory CLL Treated with Liso-Cel, a CD19-Directed CAR T-Cell Product: Preliminary Results from Transcend CLL 004, a Phase 1/2 Study Including Patients with High-Risk Disease Previously Treated with Ibrutinib

Tanya Siddiqi, MD, Jacob D. Soumerai, MD, William G. Wierda, MD PhD, Jason A. Dubovsky, PhD, Heidi H. Gillenwater, MD, Lucy Gong, PharmD, Alan Mitchell, MSc, Jerill Thorpe, BSc, Lin Yang, PhD, Kathleen A. Dorritie, MD

Blood (2018) 132 (Supplement 1): 300.

https://doi.org/10.1182/blood-2018-99-110462

Published: 2018

Journal Articles

Chemoresistant Colorectal Cancer (CRC) Cells Show Increased Invasive Potential Which Is Part Is Mediated By VEGF-Signaling and Can be Attenuated By VEGF-Directed Agents

Thouroude Sandrine, Patrick Van Dreden, PhD, Grigorios T. Gerotziafas, Annette Larsen

Blood (2018) 132 (Supplement 1): 4974.

https://doi.org/10.1182/blood-2018-99-110202

Published: 2018

Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3468.

https://doi.org/10.1182/blood.V130.Suppl_1.3468.3468

Published: 2017

Journal Articles

Transcriptomal Evidence for Dysregulation of Angiogenic Factors and Inflammatory Markers after Allogeneic Hematopoietic Cell Transplantation

Laura F. Newell, MD, Kristina Vartanian, Christina A Harrington, PhD, Shernan G. Holtan, MD

Blood (2017) 130 (Supplement 1): 3259.

https://doi.org/10.1182/blood.V130.Suppl_1.3259.3259

Published: 2017

Journal Articles

Distinct Biomarkers Reflect Pathophysiological Differences of Sickle Cell Disease Sub-Phenotypes: Viscosity-Vaso-Occlusion Vs. Hemolysis-Endothelial Dysfunction

Ioannis Papassotiriou, PhD, Christos Poziopoulos, MD, Katerina Larissi, MD, Alexandra Margeli, Marianna Politou, MD, Evangelos Terpos, MD, Ersi Voskaridou

Blood (2017) 130 (Supplement 1): 3520.

https://doi.org/10.1182/blood.V130.Suppl_1.3520.3520

Published: 2017

Journal Articles

Methacholine Challenge Test Reveals a High Prevalence of Subclinical Severe Airway Hyper-Reactivity in Children and Yound Adults with Sickle Cell Disease Which Correlates with Higher Sickle Acute Events and Acute Chest

Marthe-Sandrine Eiymo Mwa Mpollo, PhD, Sharat Chandra, MBBS,MD, Michael R. DeBaun, MD MPH, Uwe Christians, MD PhD, William Hardie, MD, Karen Kalinyak, MD, Punam Malik, MD

Blood (2017) 130 (Supplement 1): 761.

https://doi.org/10.1182/blood.V130.Suppl_1.761.761

Published: 2017

Journal Articles

The Cell Surface NADH Oxidase ENOX2 Is Highly Expressed in Chronic Myeloid Leukemia (CML): a Redox Protein As a Secreted Surrogate Biomarker and Druggable Target

Seda Baykal, Maud Voldoire, MD, Christophe Desterke, Nathalie Sorel, Hyacinthe Atchroue Johnson Ansah, Agnes Guerci-Bresler, MD, Jean-Claude Chomel, PharmD PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD, PhD

Blood (2016) 128 (22): 3059.

https://doi.org/10.1182/blood.V128.22.3059.3059

Published: 2016

Journal Articles

The Growth Differentiation Factor-15 Levels Are Increased in Patients with Compound Heterozygous Sickle Cell and Beta-Thalassemia, Correlate with Hepcidin-25/Ferritin Molar Ratio and with Markers of Hemolysis, Endothelial Dysfunction and Angiogenesis

Ioannis Papassotiriou, PhD, Katerina Larrisi, MD, Alexandra Margeli, PhD, Dimitrios Christoulas, Maria Dimopoulou, MD, Vaughn Ostland, PhD, Christos Poziopoulos, Mark Westerman, PhD, Marianna Politou, MD, Ersi Voskaridou, MD, Evangelos Terpos, MD PhD

Blood (2016) 128 (22): 3646.

https://doi.org/10.1182/blood.V128.22.3646.3646

Published: 2016

Journal Articles

Placental Growth Factor (PlGF) Enhances TLR/MK2 Dependent TNF Gene Transcription and Dissociates miRNAs Targeting TNF Regulatory Transcripts from the Polysome

Laura F. Newell, MD, Nicholas Burwick, MD, Christina A Harrington, PhD, Kristina Vartanian, Julja Burchard, Shernan G. Holtan, MD, Akiko Shimamura, MD PhD, Grover C. Bagby, MD

Blood (2016) 128 (22): 408.

https://doi.org/10.1182/blood.V128.22.408.408

Published: 2016

Journal Articles

The Pathophysiologic Role of JunB in Multiple Myeloma Pathogenesis: Focus on Bone Marrow Angiogenesis

Stefano Malvestiti, Fengjuan Fan, PhD, Muhammad Hasan Bashari, MD, Eugenio Morelli, MD, Sonia Vallet, MD, Martin Sattler, PhD, Latifa Bakiri, PhD, Anja Seckinger, MD, Dirk Hose, MD, Hartmut Goldschmidt, MD, Inka Zörnig, PhD, Martin Pecherstorfer, MD, Erwin Wagner, PhD, Pierfrancesco Tassone, MD, Dirk Jäger, MD, Klaus Podar, MD MSc PhD

Blood (2016) 128 (22): 2091.

https://doi.org/10.1182/blood.V128.22.2091.2091

Published: 2016

Journal Articles

Circulating Adiponectin and Markers of Endothelial and Cardiovascular Dysfunction Correlate with Disease Burden in Newly Diagnosed Patients with Multiple Myeloma; Increase of Adiponectin after Bortezomib- and IMiD-Based Regimens

Evangelos Terpos, Ioannis Papassotiriou, Efstathios Kastritis, MD, Gerasimos-Petros Papassotiriou, Dimitrios Christoulas, Nikolaos Kanellias, Anna Komitopoulou, Evangelos Eleutherakis-Papaiakovou, Ioannis Panagiotidis, Maria Gavriatopoulou, Emilia Mantzou, Meletios A. Dimopoulos

Blood (2016) 128 (22): 4446.

https://doi.org/10.1182/blood.V128.22.4446.4446

Published: 2016

Journal Articles

Follistatin and Endoglin: Potential Biomarkers of Endothelial Damage and Non-Relapse Mortality after Myeloablative Allogeneic Hematopoietic Cell Transplantation in Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0402

Laura F. Newell, MD, Todd E. DeFor, MS, Corey S. Cutler, MD MPH, Michael R. Verneris, MD, Bruce R. Blazar, MD, Joseph H. Antin, MD, Alan Howard, PhD, Juan Wu, Margaret L. MacMillan, MD, Angela Panoskaltsis-Mortari, PhD, Daniel J. Weisdorf, MD, Shernan G. Holtan, MD

Blood (2016) 128 (22): 63.

https://doi.org/10.1182/blood.V128.22.63.63

Published: 2016

Journal Articles

Placental Growth Factor Enhances Toll-like Receptor-Induced Inflammatory Cytokine Gene Expression Transcriptionally in Human Mononuclear Phagocytes

Laura F Newell, MD, Shernan G. Holtan, MD, Jason Rosenzweig, PhD, Jane Yates, Michael Garbati, PhD BS, R. K. Rathbun, Winifred Keeble, BS, Jeffrey W. Tyner, PhD, Irina Burd, MD PhD, Grover C. Bagby, MD

Blood (2015) 126 (23): 1006.

https://doi.org/10.1182/blood.V126.23.1006.1006

Published: 2015

Journal Articles

Cyclophosphamide and Fludarabine Conditioning Chemotherapy Induces a Key Homeostatic Cytokine Profile in Patients Prior to CAR T Cell Therapy

Adrian Bot, MD PhD, John M. Rossi, MS, Yizhou Jiang, PhD, Lynn Navale, MS, Yueh-wei Shen, MS, Marika Sherman, MS, Armen Mardiros, PhD, Sean C. Yoder, MS, William Y. Go, MD PhD, Steven A. Rosenberg, MD PhD, Jeff Wiezorek, MD MS, David D. Chang, MD PhD, James N. Kochenderfer, MD, Margo R. Roberts, PhD

Blood (2015) 126 (23): 4426.

https://doi.org/10.1182/blood.V126.23.4426.4426

Published: 2015

Journal Articles

Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness

Marthe-Sandrine Eiymo Mwa Mpollo, PhD, Eric Brandt, PhD, Shiva Kumar Shanmukhappa, DVM, PhD, Paritha Arumugam, PhD, Swati Tiwari, Anastacia Loberg, Tilat Rizvi, PhD, Mark Lindsey, Bart Jonckx, PhD, Peter Carmeliet, Prof MD PhD, Vijay Kalra, Timothy Lecras, PhD, Nancy Ratner, PhD, Marsha wills-Karp, PhD, Gurjit Khurana hershey, MD PhD, Punam Malik, MD

Blood (2015) 126 (23): 977.

https://doi.org/10.1182/blood.V126.23.977.977

Published: 2015

NARROW

Pomalidomide Reduces Bleeding and Alters Expression of Angiogenesis-Related Proteins in Patients with Hereditary Hemorrhagic Telangiectasia

Non Invasive Evaluation of Bone Marrow Activity in Patients with Sickle Cell Disease: Correlation with Disease Features, Genotype, Markers of Erythropoiesis, Iron Metabolism and Hydroxyurea Treatment

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Elevated AREG/EGF Ratio Prior to Transplantation Is Associated with Pre-Transplant Clostridium Difficile Infection, Unresolved Tissue Damage, and Poorer Overall Survival

Rapid MRD-Negative Responses in Patients with Relapsed/Refractory CLL Treated with Liso-Cel, a CD19-Directed CAR T-Cell Product: Preliminary Results from Transcend CLL 004, a Phase 1/2 Study Including Patients with High-Risk Disease Previously Treated with Ibrutinib

Chemoresistant Colorectal Cancer (CRC) Cells Show Increased Invasive Potential Which Is Part Is Mediated By VEGF-Signaling and Can be Attenuated By VEGF-Directed Agents

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Transcriptomal Evidence for Dysregulation of Angiogenic Factors and Inflammatory Markers after Allogeneic Hematopoietic Cell Transplantation

Distinct Biomarkers Reflect Pathophysiological Differences of Sickle Cell Disease Sub-Phenotypes: Viscosity-Vaso-Occlusion Vs. Hemolysis-Endothelial Dysfunction

Methacholine Challenge Test Reveals a High Prevalence of Subclinical Severe Airway Hyper-Reactivity in Children and Yound Adults with Sickle Cell Disease Which Correlates with Higher Sickle Acute Events and Acute Chest

The Cell Surface NADH Oxidase ENOX2 Is Highly Expressed in Chronic Myeloid Leukemia (CML): a Redox Protein As a Secreted Surrogate Biomarker and Druggable Target

The Growth Differentiation Factor-15 Levels Are Increased in Patients with Compound Heterozygous Sickle Cell and Beta-Thalassemia, Correlate with Hepcidin-25/Ferritin Molar Ratio and with Markers of Hemolysis, Endothelial Dysfunction and Angiogenesis

Placental Growth Factor (PlGF) Enhances TLR/MK2 Dependent TNF Gene Transcription and Dissociates miRNAs Targeting TNF Regulatory Transcripts from the Polysome

The Pathophysiologic Role of JunB in Multiple Myeloma Pathogenesis: Focus on Bone Marrow Angiogenesis

Circulating Adiponectin and Markers of Endothelial and Cardiovascular Dysfunction Correlate with Disease Burden in Newly Diagnosed Patients with Multiple Myeloma; Increase of Adiponectin after Bortezomib- and IMiD-Based Regimens

Follistatin and Endoglin: Potential Biomarkers of Endothelial Damage and Non-Relapse Mortality after Myeloablative Allogeneic Hematopoietic Cell Transplantation in Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0402

Placental Growth Factor Enhances Toll-like Receptor-Induced Inflammatory Cytokine Gene Expression Transcriptionally in Human Mononuclear Phagocytes

Cyclophosphamide and Fludarabine Conditioning Chemotherapy Induces a Key Homeostatic Cytokine Profile in Patients Prior to CAR T Cell Therapy

Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness

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American Society of Hematology

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American Society of Hematology

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