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Journal Articles

Distinct Mechanisms Underlying the Ex Vivo Expansion of Human Cord Blood Stem Cells with Different Strategies Currently Used for Allogeneic Transplantation

Luena Papa, PhD, Mansour Djedaini, BS, Christoph Schaniel, PhD, Ronald Hoffman, MD

Blood (2019) 134 (Supplement_1): 4470.

https://doi.org/10.1182/blood-2019-127040

Published: 2019

Journal Articles

In silico Prediction Followed By in Vitro validation Identifies the Survivin Inhibitor YM155 As a Potent Secondary Drug Against Pi-Resistant Myeloma

Harish Kumar, PhD, Ujjal Kumar Mukherjee, PhD, Li Chen, PhD, Amit Kumar Mitra, PhD MSc, BSc

Blood (2019) 134 (Supplement_1): 5543.

https://doi.org/10.1182/blood-2019-131923

Published: 2019

Journal Articles

NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death

Frank Cichocki, PhD, Karrune Woan, MD PhD, Cheng-Ying Wu, Bruce R. Blazar, MD, Ryan Bjordahl, PhD, Bahram Valamehr, PhD, Jeffrey S. Miller, MD

Blood (2019) 134 (Supplement_1): 3215.

https://doi.org/10.1182/blood-2019-124490

Published: 2019

Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc

Blood (2019) 134 (Supplement_1): 3718.

https://doi.org/10.1182/blood-2019-131124

Published: 2019

Journal Articles

Targeting NMNAT1 in Acute Myeloid Leukemia

Xiangguo Shi, PhD, Daisuke Nakada, PhD, Ayumi Kitano, Rebecca Murdaugh, BS, Yu-Jung Tseng, BS,MS, Kevin Hoegenauer, Tianyuan Hu, PhD, Yajian Jiang, BS

Blood (2019) 134 (Supplement_1): 879.

https://doi.org/10.1182/blood-2019-132139

Published: 2019

Journal Articles

Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia

Pu Zhang, Lindsey Brinton, PhD, James S. Blachly, MD, John C. Byrd, MD, Rosa Lapalombella, PhD

Blood (2019) 134 (Supplement_1): 2072.

https://doi.org/10.1182/blood-2019-129036

Published: 2019

Journal Articles

Rheological Effects of L-Glutamine in Patients with Sickle Cell Disease

Celeste K. Kanne, BA, Varun Reddy, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 3567.

https://doi.org/10.1182/blood-2019-128891

Published: 2019

Journal Articles

Integrated Multi-Level Omics to Characterize Bortezomib Resistance in Multiple Myeloma

Blood (2019) 134 (Supplement_1): 5534.

https://doi.org/10.1182/blood-2019-132001

Published: 2019

Journal Articles

Efficient Ex Vivo Expansion of Highly Purified Human Umbilical Cord Blood-Derived Very Small CD34 + lin - CD45 - Stem Cells into Functional Endothelial Cells in Vitro in Chemically Identified, Feeder Layer-Free Medium Supplemented with Nicotinamide

Alison Domingues, MS, Kamila Bujko, MS, Magdalena Kucia, PhD DSci, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc

Blood (2019) 134 (Supplement_1): 4882.

https://doi.org/10.1182/blood-2019-125819

Published: 2019

Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Veronika Bachanova, MD PhD, David H. McKenna, MD, Xianghua Luo, PhD, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD MS, Erica D. Warlick, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Guy Brachya, PhD, Tony Peled, MSc, Jeffrey S. Miller, MD

Blood (2019) 134 (Supplement_1): 777.

https://doi.org/10.1182/blood-2019-130476

Published: 2019

Journal Articles

Inflammatory consequences of inherited disorders affecting neutrophil function

Mary C. Dinauer

Blood (2019) 133 (20): 2130–2139.

https://doi.org/10.1182/blood-2018-11-844563

Published: 2019

Journal Articles

Leukemia Stem Cells in Relapsed AML Patients Are Uniquely Dependent on Nicotinamide Metabolism

Courtney L Jones, PhD, Brett M Stevens, PhD, Rachel Culp-Hill, BS, Travis Nemkov, Angelo D'Alessandro, PhD, Shanshan Pei, PhD, Daniel A Pollyea, MD, Craig T Jordan, PhD

Blood (2018) 132 (Supplement 1): 429.

https://doi.org/10.1182/blood-2018-99-111366

Published: 2018

Journal Articles

NAMPT Inhibitor KPT-9274 Selectively Targets Self-Renewal Capacity in Acute Myeloid Leukemia

Shaneice Renee Mitchell, BS, Nicole Grieselhuber, MD PhD, Yerdanos Asemelash, Matthew Cannon, BA, Shelley Orwick, BS, Pratibha Sharma, PhD, Virginia Goettl, DVM, PhD, Vinay K Puduvalli, MD MBBS, Deepa Sampath, PhD, Alice S. Mims, MD, James S. Blachly, MD, Amy M. Lehman, PhD, Bonnie K. Harrington, DVM, Justin Breitbach, Erkan Baloglu, William Senapedis, PhD, Rosa Lapalombella, PhD, John C. Byrd, MD

Blood (2018) 132 (Supplement 1): 3931.

https://doi.org/10.1182/blood-2018-99-119358

Published: 2018

Journal Articles

Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT) Activity Selectively Targets Human Acute Myeloid Leukemia Stem Cells

Amit Subedi, PhD, Qiang Liu, PhD BSc, David Sharon, PhD, Changjiang Xu, Veronique Voisin, PhD, Gary D Bader, Jean Wang, MD, Steven M Chan, MD PhD

Blood (2018) 132 (Supplement 1): 3932.

https://doi.org/10.1182/blood-2018-99-120258

Published: 2018

Journal Articles

The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Blood (2018) 132 (Supplement 1): 641.

https://doi.org/10.1182/blood-2018-99-117388

Published: 2018

Journal Articles

Proteometabolomics of Melphalan Resistance in Multiple Myeloma

David C. Koomen, BS, Joy D. Guingab, PhD, Paula S. Oliveira, Bin Fang, PhD, Min Liu, PhD, Eric A. Welsh, PhD, Mark B. Meads, PhD, Tuan Nguyen, Laurel E. Meke, Steven A. Eschrich, PhD, Timothy J. Garrett, PhD, John M. Koomen, PhD, Kenneth H. Shain, MD PhD

Blood (2018) 132 (Supplement 1): 5619.

https://doi.org/10.1182/blood-2018-99-117747

Published: 2018

Journal Articles

Rapid Engraftment and Immune Recovery in Treatment Refractory Severe Aplastic Anemia Patients Undergoing Ex Vivo Nicotinamide-Expanded (NAM-Expanded) Unrelated Cord Blood Transplantation

Richard W. Childs, MD, Phuong T. Vo, MD, Georg Aue, Jennifer Wilder, Brian Wells, Joseph Clara, MD, Reem Shalabi, Patricia Prince, David F. Stroncek, Robert Reger, MS, Willy A. Flegel, MD, Sharon Adams, MT, CHS (ABHI), Kristen Gunn, Tatyana Worthy, Lisa Cook, Xin Tian

Blood (2018) 132 (Supplement 1): 5789.

https://doi.org/10.1182/blood-2018-99-119546

Published: 2018

Journal Articles

SIRT6 As a Potential Therapeutic Target in Diffuse Large B-Cell Lymphoma

Juan Yang, PhD, Ying Li, MD, Ya Zhang, MD, Xiangxiang Zhou, MD, Xin Wang, MD PhD

Blood (2018) 132 (Supplement 1): 2862.

https://doi.org/10.1182/blood-2018-99-115823

Published: 2018

Journal Articles

Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

Jaap Jan Boelens, MD PhD, Coco de Koning, Mitchell E. Horwitz, MD, Guillermo Sanz, Madan Jagasia, MD MS, John E. Wagner, MD, Patrick J. Stiff, MD, Rabi Hanna, MD, Daniela Cilloni, MD PhD, Stefan Nierkens, PhD

Blood (2018) 132 (Supplement 1): 2123.

https://doi.org/10.1182/blood-2018-99-116700

Published: 2018

Journal Articles

Cell-Stage Dependent Outcomes of the NAMPT/SIRT2-Mediated Activation of LMO2 By Deacetylation in Normal Hematopoiesis and in T-ALL

Tatsuya Morishima, MD PhD, Christian Lindner, Benedikt Oswald, Marcus Hartmann, Masoud Nasri, MSc, Lothar Kanz, Patrick Müller, Karl Welte, Julia Skokowa

Blood (2017) 130 (Supplement 1): 1154.

https://doi.org/10.1182/blood.V130.Suppl_1.1154.1154

Published: 2017

NARROW

Distinct Mechanisms Underlying the Ex Vivo Expansion of Human Cord Blood Stem Cells with Different Strategies Currently Used for Allogeneic Transplantation

In silico Prediction Followed By in Vitro validation Identifies the Survivin Inhibitor YM155 As a Potent Secondary Drug Against Pi-Resistant Myeloma

NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Targeting NMNAT1 in Acute Myeloid Leukemia

Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia

Rheological Effects of L-Glutamine in Patients with Sickle Cell Disease

Integrated Multi-Level Omics to Characterize Bortezomib Resistance in Multiple Myeloma

Efficient Ex Vivo Expansion of Highly Purified Human Umbilical Cord Blood-Derived Very Small CD34 + lin - CD45 - Stem Cells into Functional Endothelial Cells in Vitro in Chemically Identified, Feeder Layer-Free Medium Supplemented with Nicotinamide

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Inflammatory consequences of inherited disorders affecting neutrophil function

Leukemia Stem Cells in Relapsed AML Patients Are Uniquely Dependent on Nicotinamide Metabolism

NAMPT Inhibitor KPT-9274 Selectively Targets Self-Renewal Capacity in Acute Myeloid Leukemia

Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT) Activity Selectively Targets Human Acute Myeloid Leukemia Stem Cells

The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Proteometabolomics of Melphalan Resistance in Multiple Myeloma

Rapid Engraftment and Immune Recovery in Treatment Refractory Severe Aplastic Anemia Patients Undergoing Ex Vivo Nicotinamide-Expanded (NAM-Expanded) Unrelated Cord Blood Transplantation

SIRT6 As a Potential Therapeutic Target in Diffuse Large B-Cell Lymphoma

Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

Cell-Stage Dependent Outcomes of the NAMPT/SIRT2-Mediated Activation of LMO2 By Deacetylation in Normal Hematopoiesis and in T-ALL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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