1-20 of 219
mutagenesis, site-directed
Close
Sort by
Journal Articles

The CXCL9 Polymorphism rs884304 Associates with Early CXCL9 Reconstitution and with Severe Chronic Graft-Versus-Host Disease (cGVHD) in Human Allograft Recipients

Hao Dai, Sivaramakrishna P. Rachakonda, PhD, Olaf Penack, MD, Aleksandar Radujkovic, MD, Carsten Müller-Tidow, MD, Rajiv Kumar, PhD, Peter Dreger, Thomas Luft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 873.
https://doi.org/10.1182/blood-2019-124742
Published: 2019
Journal Articles

Changes in N-Glycosylation Induced By Somatic Hypermutation Modulate the Antigen Reactivity of the Immunoglobulin Receptors in CLL Stereotyped Subset #201

Maria Gounari, Anastasia Iatrou, Kostantia Kotta, Ioannis Sarrigeorgiou, Peggy Lymberi, Anastasia Chatzidimitriou, Kostas Stamatopoulos
Journal: Blood
Blood (2019) 134 (Supplement_1): 1733.
https://doi.org/10.1182/blood-2019-127852
Published: 2019
Journal Articles

The AHI-1-BCR-ABL-DNM2 Complex Mediates Mitochondrial Dynamics in Drug-Resistant BCR-ABL + Cells

Ryan Yen, BSc, Lambert Yue, BSc, Steven Pelech, PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 189.
https://doi.org/10.1182/blood-2019-128712
Published: 2019
Journal Articles

CHD1 - a Novel Epigenetic Regulator in Myeloid Malignancies with a Role in DNA Repair

Arpan Sinha, MBBS, MD, Adriana De La Garza, PhD, Amit Verma, MD, J. Kimble Frazer, MD PhD, Teresa V. Bowman, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2607.
https://doi.org/10.1182/blood-2018-99-114259
Published: 2018
Journal Articles

A Case of CCDC6-RET Fusion Mutation in Adult Acute Lymphoblastic Leukemia (ALL), a Known Activating Mutation Unreported in ALL

Mateo Mejia Saldarriaga, MD, Amir Steinberg, MD, Adam F. Binder, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5136.
https://doi.org/10.1182/blood-2018-99-112652
Published: 2018
Journal Articles

Suppression of GATA3 Binding Drives Selective Abrogation of NOTCH1-MYC Enhancer Activity By Nucleosome Invasion in Thymocyte Development and Leukemia

Laura Belver, PhD, Alexander Y Yang, Daniel Herranz, PharmD, Aidan Quinn, Francesco G Brundu, PhD, Pablo Perez-Duran, PhD, Silvia Alvarez, PhD, Devya Gurung, Pedro P Rocha, PhD, Ramya Raviram, PhD, Marissa Rashkovan, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 545.
https://doi.org/10.1182/blood-2018-99-119423
Published: 2018
Journal Articles

Mutations in the NOTCH1 PEST Domain Enhance the Expression of CCL17 By Displacing the Transcription Factor HDAC1 in Chronic Lymphocytic Leukemia

Zhenshu Xu, MD PhD, Shifen Wang, Xiuli Chen, Xueting Liang, Huixin Liang, Tingting Wang
Journal: Blood
Blood (2018) 132 (Supplement 1): 4408.
https://doi.org/10.1182/blood-2018-99-116388
Published: 2018
Journal Articles

Site-Directed Pegylation at Specific Sites Significantly Prolongs the Half-Life of A1A2A3-VWF By Markedly Attenuating LRP1-Mediated Clearance

Jamie M O'Sullivan, Judicael Fazavana, PhD, Alain Chan, PhD, Niamh Cooke, PhD, Virginie Terraube, Justin Cohen, PhD, Debra D Pittman, MS, Orla Cunningham, PhD, Matthew Lambert, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1165.
https://doi.org/10.1182/blood-2018-99-114966
Published: 2018
Journal Articles

Von Willebrand Factor Binding to Myosin Assists in Coagulation

Veronica H Flood, MD, Tricia L Slobodianuk, BS, Daniel A Keesler, BS, Hannah Lohmeier, Scot A Fahs, Robert R Montgomery, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 22.
https://doi.org/10.1182/blood-2018-99-113105
Published: 2018
Journal Articles

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Soracha E Ward, BSc, Jamie M O'Sullivan, Sonia Aguila Martinez, BSc, PhD, Clive Drakeford, BSc, Thomas Anthony Jude McKinnon, BSc, PhD, Alain Chion, BSc, PhD, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 980.
https://doi.org/10.1182/blood-2018-99-114775
Published: 2018
Journal Articles

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles

Clinical Trials & Observations
Johannes C. Hellmuth, Abner Louissaint, Jr, Monika Szczepanowski, Sarah Haebe, Alessandro Pastore, Stefan Alig, Annette M. Staiger, Sylvia Hartmann, Robert Kridel, Matthew D. Ducar, Peter Koch, Martin Dreyling, Martin-Leo Hansmann, German Ott, Andreas Rosenwald, Randy D. Gascoyne, David M. Weinstock, Wolfgang Hiddemann, Wolfram Klapper, Oliver Weigert
Journal: Blood
Blood (2018) 132 (16): 1695–1702.
https://doi.org/10.1182/blood-2018-03-837252
Published: 2018
Includes: Supplemental data
Journal Articles

Functional Analyses of BTK Mutations in Follicular Lymphoma

Nan Hu, PhD, Fangyang Wang, Denzil Bernard, Shaomeng Wang, Mark Kaminski, Sumana Devata, MD, Tycel J. Phillips, MD, Sami N. Malek, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 647.
https://doi.org/10.1182/blood.V130.Suppl_1.647.647
Published: 2017
Journal Articles

Targeted-Capture Sequencing Approach to V(D)J Rearrangement, Immunoglobulin (Ig) Translocation and Mutation Detection in Multiple Myeloma (MM): Potential Applications in Minimal Residual Disease (MRD) Analysis and Comparison to Multiparameter Flow Cytometry (MFC) in the Myeloma Canada Research Network (MCRN) 001 Study with Intravenous Busulfan and Melphalan (BuMel) Conditioning Followed By Lenalidomide Maintenance in Newly Diagnosed Multiple Myeloma (NDMM)

Signy Chow, MD FRCP(C), Donna Reece, MD FRCP(C), Jonathan J. Keats, PhD, P. Leif Bergsagel, MD, Nizar J. Bahlis, MD, Paola Neri, MD, Giovanni Piza Rodriguez, MD, Michael Sebag, MD PhD, Darrell J White, MD, Kevin Song, MD FRCP(C), Terrance Comeau, MD, Christopher P. Venner, MD, Christine I Chen, MD FRCP(C), Jean Roy, MD, Martha L Louzada, MD, Julie Stakiw, MD FRCP(C), Andrea Kew, MDFRCP(C), Vishal Kukreti, MD FRCP(C), Anca Prica, MD FRCP(C), Rodger Tiedemann, MBChB, PhD, Mariela Aura Pantoja, PhD MSc, Harminder Kaur Paul, MSc, Trevor J. Pugh, PhD, Suzanne Trudel, MD FRCP(C)
Journal: Blood
Blood (2017) 130 (Supplement 1): 3057.
https://doi.org/10.1182/blood.V130.Suppl_1.3057.3057
Published: 2017
Journal Articles

The Relevance of CD20 Targeting of Oncolytic Measles Virus in the Treatment of Adult Acute Lymphoblastic Leukemia

Katharine E Bailey, MBBS, FRCPath, MA, MRCP, Sarah Aref, MSc, Aditi Dey, PhD, Rachel J Mitchell, MSc, Richard J Burt, MBBS, Naughton J Thomas, BSc, Dina Ahmed Said Aly Okasha, MBBS, MSc, Krisztina Zuborne Alapi, MSc, Adele K Fielding, MBBS,PhDFRCP,FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 3891.
https://doi.org/10.1182/blood.V130.Suppl_1.3891.3891
Published: 2017
Journal Articles

Prohibitin Expression Level As a Companion Diagnostic Marker in Cytogenetically Normal Acute Myeloid Leukemia

Myung-Geun Shin, MD PhD, Moon James, BS, Jun Hyung Lee, MD MS, Hye-Ran Kim, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3933.
https://doi.org/10.1182/blood.V130.Suppl_1.3933.3933
Published: 2017
Journal Articles

Regulation of Factor VIII By Activated Protein C: Assessment In Vitro and In Vivo

Nicole A. Parsons, B.S., Michelle D. Ho, BS, Robert J. Davidson, BS, Nabil K. Thalji, PhDMD, Ben J. Samelson-Jones, MD PhD, Rodney M Camire, PhD, Lindsey A. George, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3650.
https://doi.org/10.1182/blood.V130.Suppl_1.3650.3650
Published: 2017
Journal Articles

Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

Louise Pettersson, MD, Yilun Chen, MSc, Anthony M George, MSc, Christina Orsmark-Pietras, PhD, Henrik Lilljebjörn, MSc, Robert Rigo, MSc, Vladimir Lazarevic, MD PhD, Thoas Fioretos, MD PhD, Gunnar Juliusson, MD PhD, Mats Ehinger, MD PhD, Lao H Saal, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3951.
https://doi.org/10.1182/blood.V130.Suppl_1.3951.3951
Published: 2017
Journal Articles

Neurofibromin 1 gene Mutations Are Recurrent Events in Adult Patients with Acute Myeloid Leukemia (AML), Associate with Poor Outcome and Refine the Adverse European Leukemianet (ELN) Risk Category

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, Alice S. Mims, MD MSCR, Christopher J. Walker, PhD, James S. Blachly, MD, Deedra Nicolet, MS, Shelley Orwick, BS, Sofia E. Maharry, Andrew Carroll, PhD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Eunice S. Wang, MD, Richard M. Stone, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 186.
https://doi.org/10.1182/blood.V130.Suppl_1.186.186
Published: 2017
Journal Articles

Engineering Human Induced Pluripotent Stem Cells with Novel Chimeric Antigen Receptors to Generate Natural Killer (NK) Cell Cancer Immunotherapies with Targeted Anti-Tumor Activity

Ye Ethan Ethan Li, MD, David Hermanson, PhD, Branden Moriarity, PhD, Ryan Bjordahl, PhD, Sajid Mahmood, PhD, Bahram Valamehr, PhD, Dan Kaufman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1905.
https://doi.org/10.1182/blood.V130.Suppl_1.1905.1905
Published: 2017
Journal Articles

Diagnostic and Prognostic Implications of Prohibitin Overexpression in Normal Karyotype Acute Myeloid Leukemia

Hye-Ran Kim, PhD, Jun Hyung Lee, MD, Min-Gu Kang, MD, Ra-Young Park, PhD, Moinul Md Hoque, B.S., Sol Jeong, B.S., Min-Seo Noh, B.S., Seok-Yong Choi, MD, PhD, Soo-Hyun Kim, MD, PhD, Jong-Hee Shin, MD, PhD, Soon-Pal Suh, MD, PhD, Myung-Geun Shin, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 1714.
https://doi.org/10.1182/blood.V128.22.1714.1714
Published: 2016