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Journal Articles

Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus–associated multicentric Castleman disease

Clinical Trials & Observations
Ramya Ramaswami, Kathryn Lurain, Cody J. Peer, Anna Serquiña, Victoria Wang, Anaida Widell, Priscila Goncalves, Seth M. Steinberg, Vickie Marshall, Jomy George, William D. Figg, Denise Whitby, Joseph Ziegelbauer, Thomas S. Uldrick, Robert Yarchoan
Journal: Blood
Blood (2020) 135 (25): 2316–2319.
https://doi.org/10.1182/blood.2019004602
Published: 2020
Includes: Supplemental data
Journal Articles

Increased mTOR activation in idiopathic multicentric Castleman disease

Daniel J. Arenas, Katherine Floess, Dale Kobrin, Ruth-Anne Langan Pai, Maya B. Srkalovic, Mark-Avery Tamakloe, Rozena Rasheed, Jasira Ziglar, Johnson Khor, Sophia A. T. Parente, Sheila K. Pierson, Daniel Martinez, Gerald B. Wertheim, Taku Kambayashi, Joseph Baur, David T. Teachey, David C. Fajgenbaum
Journal: Blood
Blood (2020) 135 (19): 1673–1684.
https://doi.org/10.1182/blood.2019002792
Published: 2020
Includes: Supplemental data
Journal Articles

Extracavitary primary effusion lymphoma presenting as a thalamic mass in a patient with multicentric Castleman disease

Kritika Krishnamurthy, Vathany Sriganeshan
Journal: Blood
Blood (2020) 135 (14): 1190.
https://doi.org/10.1182/blood.2019004506
Published: 2020
Journal Articles

A Meta-Analysis of Genetic Abnormalities and Next Generation Sequencing of Primary Cases of Castleman Disease

Alexandra Butzmann, MD, Joanna Przybyl, PhD, Kaushik Sridhar, MS, Jyoti Kumar, MDMS, Nivaz Brar, BS, James L Zehnder, Roger A Warnke, MD, Robert S. Ohgami, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5227.
https://doi.org/10.1182/blood-2019-131261
Published: 2019
Journal Articles

Type I Interferon Response Identified through Phenotypic and Transcriptional Profiling of Circulating Immune Cells during Idiopathic Multicentric Castleman Disease Flare

Ruth-Anne Langan, BA, Alberto Japp, PhD, Michael Gonzalez, PhD, Rozena Rasheed, BS, Sheila K Pierson, MS, Charlly Kao, PhD, Hakon Hakonarson, MD PhD, Frits van Rhee, MD PhD, Michael Betts, PhD, Taku Kambayashi, MD PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1046.
https://doi.org/10.1182/blood-2019-128994
Published: 2019
Journal Articles

Phase I/II Study of Lenalidomide Combined with DA-EPOCH and Rituximab (DA-EPOCH-R 2 ) in Primary Effusion Lymphoma in Patients with or without HIV

Kathryn Lurain, MDMPH, Ramya Ramaswami, MBBS,MPH, Anaida Widell, RN, Irene Ekwede, RN, Jomy George, PharmD, Maryalice Stetler-Stevenson, MD PhD, Mark Raffeld, MD, Constance M. Yuan, MD PhD, Joseph Ziegelbauer, PhD, Frank Maldarelli, MD PhD, William D. Figg, PharmD, Cody Peer, PhD, Seth M. Steinberg, PhD, Denise Whitby, Thomas S. Uldrick, MD MS, Robert Yarchoan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4096.
https://doi.org/10.1182/blood-2019-122070
Published: 2019
Journal Articles

Quantitative Changes in Serum Proteins Including CXCL13 Are Early Indicators of Response to Anti-IL6 Therapy in Idiopathic Multicentric Castleman Disease

Sheila K Pierson, MS, Laura Katz, MA, Christopher Sheild Nabel, MD PhD, Jason R Ruth, PhD, Sheila Diamond, MS, CGC, Hrishikesh Karvir, PhD, Fanyi Zhang, MS, Manjula P Reddy, MS, MSc, Mary Guilfoyle, MS, Craig Tendler, MD, Frits van Rhee, MD PhD, Philip Beineke, MS, Ana B Oromendia, PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3599.
https://doi.org/10.1182/blood-2019-128284
Published: 2019
Journal Articles

Evaluation of Japanese and International Diagnostic Criteria for Idiopathic Castleman Disease

Makoto Ide, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4873.
https://doi.org/10.1182/blood-2019-128212
Published: 2019
Journal Articles

Natural History Study of Idiopathic Multicentric Castleman Disease Identifies Effective Treatments for a Large Proportion of Patients but Treatment-Refractory Patients Remain

Sheila K Pierson, MS, Yue Ren, Johnson Khor, Eric Haljasmaa, Jasira Ziglar, Katherine Floess, Erin NaPier, Faizaan Akhter, Amy Y Liu, Damilola Gibson, Karan Kanhai, MD PhD, Rabecka Martin, PhD, Amy Chadburn, MD, Gordan Srkalovic, MD PhD, Megan S. Lim, MD PhD, Corey Casper, MD MPH, Thomas S. Uldrick, MD MS, Elaine S. Jaffe, MD, Frits van Rhee, MD PhD, Hongzhe Lee, PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1540.
https://doi.org/10.1182/blood-2019-131367
Published: 2019
Journal Articles

Storming the Castle with TCP

Clinical Trials & Observations
Frits van Rhee, Katie Stone
Journal: Blood
Blood (2019) 133 (16): 1697–1698.
https://doi.org/10.1182/blood-2019-02-900803
Published: 2019
Journal Articles

Phase 2 study using oral thalidomide-cyclophosphamide-prednisone for idiopathic multicentric Castleman disease

Clinical Trials & Observations
Lu Zhang, Ai-lin Zhao, Ming-hui Duan, Zhi-yuan Li, Xin-xin Cao, Jun Feng, Dao-bin Zhou, Ding-rong Zhong, David C. Fajgenbaum, Jian Li
Journal: Blood
Blood (2019) 133 (16): 1720–1728.
https://doi.org/10.1182/blood-2018-11-884577
Published: 2019
Journal Articles

Viral, immunologic, and clinical features of primary effusion lymphoma

Clinical Trials & Observations
Kathryn Lurain, Mark N. Polizzotto, Karen Aleman, Manisha Bhutani, Kathleen M. Wyvill, Priscila H. Gonçalves, Ramya Ramaswami, Vickie Ann Marshall, Wendell Miley, Seth M. Steinberg, Richard F. Little, Wyndham Wilson, Armando C. Filie, Stefania Pittaluga, Elaine S. Jaffe, Denise Whitby, Robert Yarchoan, Thomas S. Uldrick
Journal: Blood
Blood (2019) 133 (16): 1753–1761.
https://doi.org/10.1182/blood-2019-01-893339
Published: 2019
Journal Articles

IL-13 Expression Characterizes Effusions Associated with Primary Effusion Lymphoma but Not Other Disorders Caused By Kaposi Sarcoma Herpesvirus (KSHV)

Ramya Ramaswami, MBBS, MPH, Kathryn Lurain, MD MPH, Vickie Marshall, Nazzarena Labo, MD PhD, Anaida Widell, Matthew Lindsley, Mark N. Polizzotto, Denise Whitby, Thomas S. Uldrick, MD MS, Robert Yarchoan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4137.
https://doi.org/10.1182/blood-2018-99-117668
Published: 2018
Journal Articles

A Prospective Phase II Study of Thalidomide, Cyclophosphamide and Prednisone in Newly Diagnosed Idiopathic Multicentric Castleman's Disease

Lu Zhang, MD, Ai-lin Zhao, MD, Jun Feng, MD, Xinxin Cao, MD, Yan Zhang, MD, Tienan Zhu, MD, Minghui Duan, MD, Daobin Zhou, MD, Jian Li, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4142.
https://doi.org/10.1182/blood-2018-99-113528
Published: 2018
Journal Articles

Personalized Therapy in Multicentric Castleman Disease Produces Excellent Outcomes in a Tertiary Referral Center

Katie Stone, BS, Francisco Socola, MD, Amy Greenway, Samina Waheed, Kristen Carter, APRN, Diane Glendinning, APRN, Daisy Alapat, MD, Frits van Rhee, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3701.
https://doi.org/10.1182/blood-2018-99-119510
Published: 2018
Journal Articles

Serum Proteomics Reveals Distinct Subtypes Associated with Treatment Response in Idiopathic Multicentric Castleman Disease

Dustin Shilling, PhD, Jason R Ruth, PhD, Christopher Sheild Nabel, MD PhD, Sheila K Pierson, MS, Mary Guilfoyle, MS, Craig Tendler, MD, Manjula P Reddy, MS, MSc, Michael Weinblatt, MD, Nancy Shadick, MD MPH, Mark Bower, MD, Alessia Dalla Pria, MD, Yasufumi Masaki, MD PhD, Philip Beineke, MS, Sofija Miljovska, MS, Laura Katz, MA, Sushila Shenoy, PhD, Ana B Oromendia, PhD, Jason Mezey, PhD, Jeff Wiser, MS, Jef Benbanaste, MBA, David Lee, MA, Alexander Fosså, MD PhD, Frits van Rhee, MD PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3716.
https://doi.org/10.1182/blood-2018-99-119135
Published: 2018
Journal Articles

Single-Cell RNA-Sequencing of Peripheral Blood Mononuclear Cells Reveals Changes in Immune Cell Composition and Distinct Inflammatory Gene Expression Profiles during Idiopathic Multicentric Castleman Disease Flare

Ruth-Anne Langan, BA, Dustin Shilling, PhD, Michael Gonzalez, PhD, Charlly Kao, PhD, Hakon Hakonarson, MD PhD, Taku Kambayashi, MD PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2406.
https://doi.org/10.1182/blood-2018-99-110461
Published: 2018
Journal Articles

Oligoclonal Expansion of Cd8+ T Cells during Idiopathic Multicentric Castleman Disease Flares Suggests an Antigen Driven Process

Dustin Shilling, PhD, Jason E Stadanlick, PhD, Wenzhao Meng, PhD, Abhishek Rao, MS, Vera P Krymskaya, PhD MBA, FCPP, Eline T. Luning Prak, MD, PhD, Evgeniy B Eruslanov, PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2411.
https://doi.org/10.1182/blood-2018-99-118650
Published: 2018
Journal Articles

Pi3k/Akt/Mtor Pathway Activity Is Increased in Lymph Node Tissue from Idiopathic Multicentric Castleman Disease Patients with Tafro Syndrome

Dustin Shilling, PhD, Dale M Kobrin, BA, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 1121.
https://doi.org/10.1182/blood-2018-99-118434
Published: 2018
Journal Articles

Pilot Study of Tocilizumab in Patients with HIV and Symptomatic Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease

Ramya Ramaswami, MBBS, MPH, Kathryn Lurain, MD MPH, Anaida Widell, Mark N. Polizzotto, Priscila H. Goncalves, MD, Matthew Lindsley, Seth M. Steinberg, PhD, Denise Whitby, Thomas S. Uldrick, MD MS, Robert Yarchoan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2018-99-113119
Published: 2018