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Journal Articles

Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing

Erica B. Esrick, MD, Maureen Achebe, MD MPH, Myriam Armant, PhD, Pablo Bartolucci, MD PhD, Marioara Felicia Ciuculescu, MD, Heather Daley, Colleen Dansereau, MSN, RN, CPN, Giuseppe Di Caprio, PhD, Bronner Goncalves, MD PhD, Nicolas Hebert, Matthew M Heeney, MD, John M. Higgins, MD PhD, Leslie E. Lehmann, MD, John P Manis, MD, Olivier Negre, PhD, Sarah Nikiforow, MD PhD, Ethan Schonbrun, PhD, David K. Wood, PhD, David A. Williams, MD
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-5.
https://doi.org/10.1182/blood-2019-132745
Published: 2019
Journal Articles

Engagement in Cognitive-Behavioral Therapy for Chronic Pain Management Is Associated with Reductions in Healthcare Utilization in Pediatric Sickle Cell Disease

Soumitri Sil, PhD, Kristina Lai, MPH, Jennifer L. Lee, PhD, Jordan Gilleland-Marchak, PhD ABPP, Beth Thompson, PhD, Lindsey L Cohen, PhD, Peter A. Lane, MD, Carlton Dampier, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 418.
https://doi.org/10.1182/blood-2019-130580
Published: 2019
Journal Articles

Phase-I Study of ETA Receptor Antagonist Ambrisentan in Sickle Cell Disease

Abdullah Kutlar, MD, Jennifer Pollock, PhD, Steffen E. Meiler, MD, Ryan Harris, PhD CEP, FACSM, Xu Hongyan, PhD, Leigh Wells, MSN, Latanya Bowman, RN, Sharon Jones, BS, David M. Pollock, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 617.
https://doi.org/10.1182/blood-2019-130036
Published: 2019
Journal Articles

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

David C Rees, Yurdanur Kilinc, MD, Selma Unal, Carlton Dampier, MD, Betty S. Pace, MD, Banu Kaya, MD, Sara Trompeter, MBChB BSc MRCPCH FRCPath MSc, Isaac Odame, Johnny N Mahlangu, MBBCH, MMed, FCPath, Sule Unal, MD, Julie Brent, MD, Regine Grosse, MD, Beng R. Fuh, MD, Baba PD Inusa, MD, Ariel Koren, MD, Carina Levin, MD PhD, Steven Mortier, Elizabeth McNamara, Yue Li, Stephen John Oliver, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 615.
https://doi.org/10.1182/blood-2019-123355
Published: 2019
Journal Articles

Patient Perception on Health Care Delivery for Sickle Cell Disease and Opportunities for Quality Improvement

Ofelia A. Alvarez, MD, Sandra Echenique, Hector Rodriguez-Cortes, MD, Thomas J. Harrington, MD, E. Leila Jerome Clay, MD MCTS, FAAP, Vandy Black, MDMSc, Mary Murph, Christopher Wells, Ifeyinwa (ify) Osunkwo, MDMPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 5862.
https://doi.org/10.1182/blood-2019-123215
Published: 2019
Journal Articles

Crizanlizumab Treatment Is Associated with Clinically Significant Reductions in Hospitalization in Patients with Sickle Cell Disease: Results from the Sustain Study

Kenneth I. Ataga, MD, Abdullah Kutlar, MD, Laurie DeBonnett, MD, Jeremie Lincy, Julie Kanter, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2289.
https://doi.org/10.1182/blood-2019-125868
Published: 2019
Journal Articles

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

Umapathy N Siddaramappa, PhD, Niren Patel, MBBS, Betty S. Pace, MD, Abdullah Kutlar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2258.
https://doi.org/10.1182/blood-2019-130924
Published: 2019
Journal Articles

Trends in Hydroxyurea Utilization for the Treatment of Sickle Cell Anemia in Florida

Vandy Black, MDMSc, Jasmine A Mack, MPH, Jaclyn Hall, PhD, Heather Morris, PharmD, BCPS, Elizabeth Shenkman, PhD, Matthew J Gurka, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2293.
https://doi.org/10.1182/blood-2019-125799
Published: 2019
Journal Articles

Safety of Intravenous Arginine Therapy in Children with Sickle Cell Disease Hospitalized for Vaso-Occlusive Pain: A Randomized Placebo-Controlled Trial in Progress

Claudia R. Morris, MD, Janet Figueroa, MPH, Amanda Watt, Kirshma Khemani, MD, Polly Kumari, MBBS, Morgan Barnett, MPH, Nitya Bakshi, MBBS, MS, Peter A. Lane, MD, Carlton Dampier, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 995.
https://doi.org/10.1182/blood-2019-122983
Published: 2019
Journal Articles

Crizanlizumab 5.0 Mg/Kg Exhibits a Favorable Safety Profile in Patients with Sickle Cell Disease: Pooled Data from Two Phase II Studies

Julie Kanter, MD, Darla K Liles, MD, Kim Smith-Whitley, MD, Clark Brown, MD PhD, Abdullah Kutlar, MD, Brian Elliott, Amit Shah, Jeremie Lincy, Susan Poggio, Kenneth I. Ataga, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 991.
https://doi.org/10.1182/blood-2019-123965
Published: 2019
Journal Articles

Methotrexate-Loaded Biodegradable Polymeric Micelles for Lymphoma Therapy in Mouse Model

Mengyao Wang, MD, Ying Qu, PhD, Zhiyong Qian, PhD, Ting Niu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4181.
https://doi.org/10.1182/blood-2018-99-119151
Published: 2018
Journal Articles

Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

Louise Pettersson, MD, Yilun Chen, MSc, Anthony M George, MSc, Christina Orsmark-Pietras, PhD, Henrik Lilljebjörn, MSc, Robert Rigo, MSc, Vladimir Lazarevic, MD PhD, Thoas Fioretos, MD PhD, Gunnar Juliusson, MD PhD, Mats Ehinger, MD PhD, Lao H Saal, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3951.
https://doi.org/10.1182/blood.V130.Suppl_1.3951.3951
Published: 2017
Journal Articles

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Xu Han, BS, MS, Lukas Hofmann, PhD, Maria de la Fuente, BS, Tivadar Orban, PhD, Nathan Alexander, PhD, Krzysztof Palczewski, PhD, Marvin T Nieman, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 453.
https://doi.org/10.1182/blood.V130.Suppl_1.453.453
Published: 2017
Journal Articles

CCL3 Signaling Is Essential for Leukemia Progression but Dispensable for Hematopoietic Stem Cell Maintenance

Rhonda J. Staversky, BS, Mary A Georger, B.S., Marian Ackun-Farmmer, B.S., Michael W. Becker, MD, Danielle S.W. Benoit, PhD, Laura M. Calvi, MD, Benjamin J. Frisch, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2603.
https://doi.org/10.1182/blood.V130.Suppl_1.2603.2603
Published: 2017
Journal Articles

Factor XIII Contributes to Clot Formation and Thrombin Generation

M Rick Rollins, Emily A Larson, Hillary J Larson, Jason A Taylor, MD PhD
Journal: Blood
Blood (2016) 128 (22): 208.
https://doi.org/10.1182/blood.V128.22.208.208
Published: 2016
Journal Articles

The Nitric Oxide-Generating Prodrug Js-K Is Selectively Toxic Towards AML Compared to Normal Human Hematopoietic Cells

Kristi J. Smock, MD, William L. Heaton, MS, Anthony D. Pomicter, MS, Ronda A Crist, MT, Ken M Kosak, BS, Kenneth M Boucher, PhD, George M. Rodgers, MD PhD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD, Paul J Shami, MD
Journal: Blood
Blood (2016) 128 (22): 5217.
https://doi.org/10.1182/blood.V128.22.5217.5217
Published: 2016
Journal Articles

The Nitric Oxide-Generating Prodrug Js-K Reverses the Multi-Drug Resistance Phenotype in AML Cells

Stephan Morys, BS, Catherine Gannage, Moises Terrazas, MS, Imit Kaur, PhD, Ken M Kosak, BS, Paul J Shami, MD
Journal: Blood
Blood (2016) 128 (22): 5127.
https://doi.org/10.1182/blood.V128.22.5127.5127
Published: 2016
Journal Articles

Cathepsin-Cleavable BIM BH3 Peptide Amphiphiles Are Potent Inducers of Cellular Apoptosis

Joseph Bellairs, Ravand Samaeekia, Handan Acar, PhD, Matthew Tirrell, PhD, James LaBelle, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4438.
https://doi.org/10.1182/blood.V126.23.4438.4438
Published: 2015
Journal Articles

Novel Multistage Nanoparticle Drug Delivery to Ablate Leukemia Stem Cells in Their Niche.

Hongliang Zong, MD, PhD, Siddhartha Sen, PhD, Guodong Zhang, PhD, David G Gorenstein, PhD, Xuewu Liu, PhD, Mauro Ferrari, PhD, Gail J. Roboz, MD, Haifa Shen, MD, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2012) 120 (21): 2631.
https://doi.org/10.1182/blood.V120.21.2631.2631
Published: 2012
Journal Articles

Skeletal-Targeted, Osteolytic-Responsive Drug Delivery System Improves Anti-Tumor Efficacy in Multiple Myeloma.

Xuli Wang, PhD, Ye Yang, PhD, Scott Miller, PhD, Fenghuang Zhan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3155.
https://doi.org/10.1182/blood.V120.21.3155.3155
Published: 2012