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Journal Articles

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Theresa Hack, MSc, Stefanie Bertram, MD, Guntram Büsche, MD, Helmut Hanenberg, MD, Ludger Klein-Hitpass, PhD, Nils Von Neuhoff, PhD, Dirk Reinhardt, MD, Markus Schneider, PhD, Mareike Rasche, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3734.
https://doi.org/10.1182/blood-2019-126536
Published: 2019
Journal Articles

Characterization of a Novel JAK1 Pseudokinase Mutation in the First Case of Trisomy 21-Independent GATA1-Mutated Transient Abnormal Myelopoiesis

Julius Lukes, Jr., MD, Petr Danek, MSc, Oriol Alejo, Eliska Potuckova, Ondrej Gahura, Dirk Heckl, PhD, Julia Starkova, PhD, Jan Zuna, Jan Stary, Prof., MD PhD, Jan Trka, Prof., MD PhD, Jan-Henning Klusmann, Marketa Zaliova, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4208.
https://doi.org/10.1182/blood-2019-122168
Published: 2019
Journal Articles

An in Vitro Study on the Role of Angiogenesis in Iron Deficiency Induced Reactive Thrombocytosis

Pedro De Alarcon, MD, Manu Gnanamony, PhD, Jessica Garcia, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2450.
https://doi.org/10.1182/blood-2018-99-115378
Published: 2018
Journal Articles

Chromosome 21 Gain Is Dispensable for Transient Myeloproliferative Disorder (TMD) Development

Julius Lukes, Jr., MD, Eliska Potuckova, Julia Starkova, Jan Stary, MD PhD, Jan Zuna, Jan Trka, MD PhD, Marketa Zaliova
Journal: Blood
Blood (2018) 132 (Supplement 1): 2764.
https://doi.org/10.1182/blood-2018-99-112078
Published: 2018
Journal Articles

Activation Mediated By Peroxisome Proliferator-Activated Receptor (PPAR) Ligands and Brown Algae-Based Compounds: Different Mechanisms between Megakaryoblasts and Mature Platelets

Jin-Yeong Han, MD PhD, Jae-Lim Choi, Ri-Young Goh, Hyeon-Ho Lim, Joo-In Park
Journal: Blood
Blood (2017) 130 (Supplement 1): 4832.
https://doi.org/10.1182/blood.V130.Suppl_1.4832.4832
Published: 2017
Journal Articles

Identification of Candidate Progenitor Populations Which Causes Transient Abnormal Myelopoiesis

Yoko Nishinaka-Arai, PhD, Akira Niwa, MD, Shiori Matsuo, B.S., Yasuhiro Kazuki, PhD, Yuwna Yakura, PhD, Mitsuo Oshimura, PhD, Tatsutoshi Nakahata, MD, PhD, Megumu K Saito, MD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1659.
https://doi.org/10.1182/blood.V130.Suppl_1.1659.1659
Published: 2017
Journal Articles

Mass Cytometry Analysis Reveals Cellular Loci of Cytokine Overproduction in Myelofibrosis with Differential Sensitivity to Ruxolitinib

Daniel A.C. Fisher, PhD, Cathrine Miner, Elizabeth Engle, PhD, Taylor B. Collins, Hengrui Hu, Olga Malkova, Stephen Oh, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4209.
https://doi.org/10.1182/blood.V130.Suppl_1.4209.4209
Published: 2017
Journal Articles

Overexpression of KDM6B, an Epigenetic and Innate Immune Regulator, Results in Hematopoietic Alterations of Mice Including Changes in Hematopoietic Stem Cells

Yue Wei, PhD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Simona Colla, PhD, Carlos E Bueso-Ramos, MD PhD, Joseph D Khoury, MD, Zachary S. Bohannan, MA, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2016) 128 (22): 3149.
https://doi.org/10.1182/blood.V128.22.3149.3149
Published: 2016
Journal Articles

Megakaryocyte Expansion and Platelet CD34 Expression Observed in GFI1B Q287* -Related Bleeding and Platelet Disorder Is Caused By Quenching of the Lysine Specific Demethylase LSD1/KDM1A

Rinske van Oorschot, MSc, Anna E. Marneth, MSc, Marten Hansen, BSc, Saskia M. Bergevoet, Alexander B. Meijer, PhD, Britta A.P. Laros-van-Gorkom, MD PhD, Joop H. Jansen, PhD, Marieke Von Lindern, PhD, Emile van den Akker, PhD, Bert A. van der Reijden, PhD
Journal: Blood
Blood (2016) 128 (22): 363.
https://doi.org/10.1182/blood.V128.22.363.363
Published: 2016
Journal Articles

Megakaryocytic Fate Specification and Maturation

Diane S Krause, MD PhD
Journal: Blood
Blood (2015) 126 (23): SCI-2.
https://doi.org/10.1182/blood.V126.23.SCI-2.SCI-2
Published: 2015
Journal Articles

Recapitulation of Transient Abnormal Myelopoiesis Using Patient Derived iPSCs

Yoko Nishinaka-Arai, PhD, Akira Niwa, MD, PhD, Mitsujiro Osawa, PhD, Tatsutoshi Nakahata, MD, PhD, Megumu K Saito, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 4115.
https://doi.org/10.1182/blood.V126.23.4115.4115
Published: 2015
Journal Articles

Next Generation Sequencing Identifies a Novel Subset of Non-Down Syndrome Acute Megakaryoblastic Leukemia Characterized By Chimeric Transcripts Involving HOX Cluster Genes

Jasmijn de Rooij, MD, Cristyn Branstetter, MD, Jing Ma, PhD, Yongjin Li, PhD, Jinjun Cheng, MD PhD, Cary Koss, BS, John Easton, PhD, Lonneke Jantine Verboon, BSc, Heather L. Mulder, BS, Michael Rusch, BA, Joshua Yew Suang Lim, BS, Katarina Reinhardt, PhD, Allen Eng Juh Yeoh, MD, Lee-Yung Shih, MD, Der-Cherng Liang, MD, Stephanie Halene, MD, Diane S Krause, MD PhD, Jinghui Zhang, PhD, James R. Downing, MD, Franco Locatelli, MD PhD, Dirk Reinhardt, MD, Marry M van den Heuvel-Eibrink, MD PhD, Maarten Forenerod, PhD, C. Michel Zwaan, MD PhD, Tanja A. Gruber, MD PhD
Journal: Blood
Blood (2015) 126 (23): 171.
https://doi.org/10.1182/blood.V126.23.171.171
Published: 2015
Journal Articles

ANP32A Dysregulation Contributes to Abnormal Megakaryopoiesis in Acute Megakaryoblastic Leukemia

Xueqin Sun, PhD, Bin Lu, PhD, Zan Huang
Journal: Blood
Blood (2015) 126 (23): 1231.
https://doi.org/10.1182/blood.V126.23.1231.1231
Published: 2015
Journal Articles

Regulation of Erythro-Megakaryocytic Lineage Divergence By the Transcriptional Repressor Gfi1b and Its Rgs Targets

Ananya Sengupta, MPhil, Ghanshyam Upadhyay, PhD, Sayani Sen, Shireen Saleque, PhD
Journal: Blood
Blood (2015) 126 (23): 2385.
https://doi.org/10.1182/blood.V126.23.2385.2385
Published: 2015
Journal Articles

Acute Megakaryocytic Leukemia (AMegL) Is Associated with Inferior Outcomes Relative to Other Acute Myeloid Leukemia (AML) Morphologies

Smith Giri, MD, Michael G Martin, MD, Ranjan Pathak, MD, Bojia Li, MD, Philippe E Prouet
Journal: Blood
Blood (2014) 124 (21): 2285.
https://doi.org/10.1182/blood.V124.21.2285.2285
Published: 2014
Journal Articles

Identification of the Human Unipotent Megakaryocyte Progenitor, and Its Pathophysiological Roles in Human Thrombopoietic Disorders

Kohta Miyawaki, MD, Hiromi Iwasaki, MD PhD, Koichi Akashi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4325.
https://doi.org/10.1182/blood.V124.21.4325.4325
Published: 2014
Journal Articles

Modeling the Multi-Step Pathogenesis of Acute Myeloid Leukemia of Down Syndrome

Eric R. Lechman, PhD, Karin G. Hermans, PhD, Stephanie M. Dobson, BSc, Olga I. Gan, PhD, James A. Kennedy, MDPhD, John Chen, PhD, Johann K. Hitzler, MD, John E. Dick, PhD
Journal: Blood
Blood (2014) 124 (21): 3579.
https://doi.org/10.1182/blood.V124.21.3579.3579
Published: 2014
Journal Articles

Ex Vivo Induction of Megakaryocytic Differentiation of Umbilical Cord Blood CD34 + Cells

Xin Guan, B.S., Meng Qin, PhD, Bin Shen, BS, Yu Zhang, B.S., Wenhong Jiang, B.S., Zhihua Ren, PhD, Yupo Ma, PhDMD, Wei Dai, PhD, Yongping Jiang, PhD
Journal: Blood
Blood (2014) 124 (21): 318.
https://doi.org/10.1182/blood.V124.21.318.318
Published: 2014
Journal Articles

Acute Megakaryoblastic Leukemia in Childhood: Comparison Between Patients with and without Down Syndrome

Maria Sara Felice, Dr., Jorge Gabriel Rossi, PhD, Marta Gallego, Cristina N. Alonso, Dr., Silvia Eandi Eberle, Myriam Ruth Guitter, Patricia L. Rubio, Elizabeth M Alfaro, Cristian Sanchez La Rosa, Pedro Zubizarreta
Journal: Blood
Blood (2014) 124 (21): 952.
https://doi.org/10.1182/blood.V124.21.952.952
Published: 2014
Journal Articles

Splenectomy in a Child of X-Linked Thrombocytopenia with Thalassemia and Bone Marrow Fibrosis : Hemoglobin and Platelet Count Were Improved

Yang Wan, Xiaofan Zhu, Xiaojuan Chen, Wenbin An, Peihong Zhang, Yingchi Zhang, Ye Guo, MD
Journal: Blood
Blood (2014) 124 (21): 1367.
https://doi.org/10.1182/blood.V124.21.1367.1367
Published: 2014