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Journal Articles

Contribution of Myeloid-Drived Suppressor Cells to Leukemia Relapse in Patients with B-ALL Who Underwent Allo-HSCT

Yang Zhou, MD, Yingjun Chang, Yu Wang, Lanping Xu, Xiaohui Zhang, Kaiyan Liu, Xiao-Jun Huang
Journal: Blood
Blood (2019) 134 (Supplement_1): 2010.
https://doi.org/10.1182/blood-2019-123723
Published: 2019
Journal Articles

Sustained Donor Chimerism and Rapid Immune Cell Reconstitution Following Familial Haploidentical (FHI) CD34 Enriched Stem Cell Transplantation with Pbmnc Addback in Patients with High Risk Sickle Cell Disease (SCD) (IND 14359)

Yaya Chu, PhD, Julie-An Talano, MD, Lee Ann Baxter-Lowe, PhD, Carolyn A. Keever-Taylor, PhD, Erin Morris, RN, BSN, Harshini Mahanti, BS, MSCR, Janet Ayello, MS, MT(ASCP), Rona Singer Weinberg, PhD, Qiuhu Shi, PhD, Theodore B. Moore, MD, Sandra Fabricatore, RN, PNP, MSN, Brenda J. Grossman, MD, Carmella van de Ven, MA, Shalini Shenoy, MD, Mitchell S Cairo, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1990.
https://doi.org/10.1182/blood-2019-126757
Published: 2019
Journal Articles

Chimeric Antigen Receptor T Cells Targeting NKG2D-Ligands Show Robust Efficacy Against Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia

Lina Driouk, MD, Joanina Gicobi, Yusuke Kamihara, MD PhD, Kayleigh Rutherford, Glenn Dranoff, MD, Jerome Ritz, MD, Susanne H.C. Baumeister, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1930.
https://doi.org/10.1182/blood-2019-130113
Published: 2019
Journal Articles

NKG2C + CD57 + Natural Killer Cells May Play an Important Role in Maintaining Virus-Specific Immune Reconstitution Post-Allogeneic HSCT

Debora Basilio Basilio-Queiros, MSc, Susanne Luther, Arnold Ganser, MD, Eva M Weissinger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1939.
https://doi.org/10.1182/blood-2019-121914
Published: 2019
Journal Articles

Combining CAR Engineering and CIS Checkpoint Deletion in NK Cells for the Treatment of B Cell Hematologic Malignancies

May Daher, MD, Rafet Basar, MD, Elif Gokdemir, BS, Natalia Baran, PhDMD, Nadima Uprety, MS, Mayela Carolina Mendt, PhD, Lucila Kerbauy, MD, Mayra Shanley, PhD, Ana Karen Nunez Cortes, MD, Li Li, MD, Pinaki P Banerjee, PhD, Vakul Mohanty, PhD, Junjun Lu, Gonca Ozcan, MD, Emily Ensley, BS, Vandana Nandivada, BS, MS, Mecit Kaplan, MS, Mustafa H Bdaiwi, MD, Enli Liu, MD, Sonny Ang, PhD, Ken Chen, PhD, Marina Y Konopleva, MD PhD, Richard E. Champlin, MD, Elizabeth J. Shpall, MD, Katayoun Rezvani, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1936.
https://doi.org/10.1182/blood-2019-126739
Published: 2019
Journal Articles

Invariant NKT Cells Recognize Leukemia Cells with T-Cell and NK Receptors in a CD1d-Independent Manner

Takahiro Aoki, MD, Mariko Takami, Tomozumi Takatani, Kiwamu Motoyoshi, Ayana Ishii, Ayaka Hara, Takahide Toyoda, Reona Okada, Moeko Hino, MD, Ryo Koyama-Nasu, Masahiro Kiuchi, Kiyoshi Hirahara, Toshinori Nakayama, Naoki Shimojo, Shinichiro Motohashi
Journal: Blood
Blood (2019) 134 (Supplement_1): 3225.
https://doi.org/10.1182/blood-2019-121817
Published: 2019
Journal Articles

Impacts of a Proliferation-Inducing Ligand on Current Therapeutic Monoclonal Antibody-Induced Cytotoxicity Against Human Multiple Myeloma Cells

Liang Lin, PhD, Shih-Feng Cho, MD PhD, Kenneth Wen, Tengteng Yu, MD PhD, Phillip A Hsieh, Yuyin Li, PhD, Gang An, MD, Lugui Qiu, MD PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3105.
https://doi.org/10.1182/blood-2019-130927
Published: 2019
Journal Articles

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Wulin Aerbajinai, MD PhD, Jianqiong Zhu, MD, Chutima Kumkhaek, PhD, Kyung Chin, Griffin Rodgers, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2318.
https://doi.org/10.1182/blood-2019-130318
Published: 2019
Journal Articles

Exploiting an Anti-CD3/CD33 Bispecific Antibody to Redirect Donor T Cells Against HLA Loss Leukemia Relapses

Pier Edoardo Rovatti, MD, Laura Zito, MSc, Eleonora Draghi, MSc, Monika Herrmann, PhD, Anetta Marcinek, MSc, Bettina Brauchle, MSc, Cesare Covino, MSc, Mattia Di Bono, MSc, Matteo Giovanni Carrabba, MD, Massimo Bernardi, MD, Karl-Peter Hopfner, PhD, Cristina Toffalori, PhD, Fabio Ciceri, MD, Marion Subklewe, MD, Luca Vago, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 513.
https://doi.org/10.1182/blood-2019-126641
Published: 2019
Journal Articles

AMG 701 Potently Induces Anti-Multiple Myeloma (MM) Functions of T Cells and IMiDs Further Enhance Its Efficacy to Prevent MM Relapse In Vivo

Shih-Feng Cho, MD PhD, Liang Lin, PhD, Lijie Xing, MD, Kenneth Wen, Tengteng Yu, MD PhD, Phillip A Hsieh, Yuyin Li, PhD, Nikhil C. Munshi, MD, Joachim Wahl, PhD, Katja Matthes, Kenneth C. Anderson, MD, Tara Chapman-Arvedson, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 135.
https://doi.org/10.1182/blood-2019-128528
Published: 2019
Journal Articles

Bromodomain and Extraterminal (BET) Domain Inhibition with PLX51107 and PLX2853 Improves Survival and Decreases Acute GVHD Severity in Murine Models

Hannah K. Choe, MD, Yandi Gao, MS, Katiri Snyder, BS, Ben Powell, PhD, Gideon Bollag, PhD, Parvathi Ranganathan, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4429.
https://doi.org/10.1182/blood-2019-122455
Published: 2019
Journal Articles

Donor and Host Coexpressing KIR Ligands Promote NK Education Post Allogeneic Hematopoietic Stem Cell Transplantation

Xingxing Yu, Xiang-Yu Zhao, Zhengli Xu, Xunhong Cao, Mingrui Huo, Xiao-Su Zhao, Ying-Jun Chang, Yu Wang, Xiaohui Zhang, Lanping Xu, Kaiyan Liu, Xiaojun Huang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4519.
https://doi.org/10.1182/blood-2019-129609
Published: 2019
Journal Articles

FT819: Translation of Off-the-Shelf TCR-Less Trac-1XX CAR-T Cells in Support of First-of-Kind Phase I Clinical Trial

Chiawei Chang, Sjoukje Van Der Stegen, PhD, Mandal Mili, PhD, Raedun Clarke, PhD, Yi-Shin Lai, PhD, Alec Witty, PhD, Pieter Lindenbergh, Bi-Huei Yang, PhD, Mushtaq Husain, PhD, Helena Shaked, PhD, Brian Groff, Laurel Stokely, Ramzey Abujarour, PhD, Tom Lee, PhD, Hui-Yi Chu, PhD, Mochtar Pribadi, PhD, Jason ORourke, PhD, Alma Gutierrez, Isabelle Riviere, PhD, Michel Sadelain, MD PhD, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4434.
https://doi.org/10.1182/blood-2019-130584
Published: 2019
Journal Articles

The Immune Micro-Environment in Diffuse Large B Cell Lymphoma Is Characterised By an Immunosuppressive Shift in T Cell Subsets

Edward Truelove, MBBS, BSc, MRCP, FRCPath, Frances Seymour, MRCP, BSc, MBBS, Joseph G Taylor, MBBS, BSc, Mariarita Calaminici, Andrew James Clear, BSc, John G. Gribben, MD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5240.
https://doi.org/10.1182/blood-2019-130712
Published: 2019
Journal Articles

The Effect of Apoptosis Inhibitor Blockade Agents on the Third Generation CD19 CAR T Cells

Mingya Yang, MD, Lei Wang, MD, Ming Ni, Maria-Luisa Schubert, MD, Brigitte Neuber, Angela Hückelhoven-Krauss, Ruben A. Gößmann, Christian Kleist, Volker Eckstein, Carsten Müller-Tidow, MD, Peter Dreger, Michael Schmitt, MD, Anita Schmitt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5620.
https://doi.org/10.1182/blood-2019-125622
Published: 2019
Journal Articles

CEBPA Gene Mutations Interfere with Expressions of NKG2D Ligands Ulbps in AML Cells and Modulate Their Susceptibility to NK-Mediated Lysis

Meng Liu, Limengmeng Wang, PhD, Huafang Wang, Shan Fu, He Huang, Haowen Xiao
Journal: Blood
Blood (2019) 134 (Supplement_1): 1257.
https://doi.org/10.1182/blood-2019-129899
Published: 2019
Journal Articles

The IRE1-XBP1s Pathway Impairment Underpins NK Cell Dysfunction in Hodgkin Lymphoma, That Is Partly Restored By PD-1 Blockade

Karolina Bednarska, Jay Gunawardana, PhD, Frank Vari, PhD, Qingyan Cui, PhD, Gayathri Thillaiyampalam, MSc, BSc, Samantha Stehbens, PhD, Sally Mujaj, PhD, Jamie Nourse, PhD, Alexandre Cristino, PhD, Maher K. Gandhi, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2795.
https://doi.org/10.1182/blood-2019-126372
Published: 2019
Journal Articles

A Bcma and CD19 Bispecific CAR-T for Relapsed and Refractory Multiple Myeloma

Hua Zhang, Lei Gao, Li Liu, Jishi Wang, PhD, Sanbin Wang, Li Gao, Cheng Zhang, MD PhD, Yao Liu, Peiyan Kong, Jia Liu, Jiaping He, Yu Han, Hua Shi, Yan He, Xun Ye, Yi Zhao, Wei Cao, Lianjun Shen, Xi Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 3147.
https://doi.org/10.1182/blood-2019-131056
Published: 2019
Journal Articles

Aberrations Detected By FISH in Brazilian Multiple Myeloma Patients

Maria de Lourdes Chauffaille, MD PhD, Aline Dos Santos Borgo Perazzio, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5509.
https://doi.org/10.1182/blood-2019-124221
Published: 2019
Journal Articles

Checkpoint Blockade in Combination with CD33 Chimeric Antigen Receptor T Cell Therapy and Hypomethylating Agent Against Acute Myeloid Leukemia

Tongyuan Xue, MD, Marissa Del Real, PhD, Emanuela Marcucci, Candida Toribio, Sonia Maryam Setayesh, Stephen J Forman, MD, David A Horne, PhD, Lihua E Budde, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1383.
https://doi.org/10.1182/blood-2019-121486
Published: 2019