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Journal Articles

DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation

Julia Meyer, PhD, Maximillian Schönung, Christian Flotho, MD PhD, Adam B. Olshen, PhD, Mark Hartmann, PhD, Christoph Plass, PhD, Yusuke Okuno, MD PhD, Yoshiyuki Takahashi, MD PhD, Norihiro Murakami, MD PhD, Manabu Wakamatsu, MD, Mignon L. Loh, MD, Charlotte M. Niemeyer, MD, Hideki Muramatsu, MD PhD, Daniel B. Lipka, MD, Elliot Stieglitz, MD

Blood (2019) 134 (Supplement_1): 1693.

https://doi.org/10.1182/blood-2019-131279

Published: 2019

Journal Articles

Genomic Landscape of Juvenile Myelomonocytic Leukemia: A Real World Context

Gaurav Chatterjee, MD, Gaurav Narula, MD, Shrinidhi Nathany, MD, Prashant Tembhare, MD, Papagudi Ganesan Subramanian, MD, Sumeet Gujral, MD, Maya Prasad, Nirmalya Roy Moulik, MD, Vasudev Bhat, Chetan A. Dhamne, MD, Shripad Banavali, MD, Nikhil Patkar, MD

Blood (2019) 134 (Supplement_1): 1728.

https://doi.org/10.1182/blood-2019-129750

Published: 2019

Journal Articles

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Mattias Hofmans, MD, Barbara Depreter, PhD PharmD, Tim Lammens, PhD, Helene Cave, PharmD, PhD, Christian Flotho, MD PhD, Henrik Hasle, Valerie de Haas, MD PhD, Charlotte M. Niemeyer, MD, Jan Stary, Prof., MD PhD, Pieter Van Vlierberghe, PhD, Jan Philippé, MD PhD, Barbara De Moerloose, MD PhD

Blood (2019) 134 (Supplement_1): 1701.

https://doi.org/10.1182/blood-2019-123715

Published: 2019

Journal Articles

Genome-Wide Methylation Analysis Using the Digital Restriction Enzyme Analysis of Methylation for Stratification of Patients with Juvenile Myelomonocytic Leukemia

Hironobu Kitazawa, Hideki Muramatsu, MD PhD, Norihiro Murakami, MD PhD, Yusuke Okuno, MD PhD, Manabu Wakamatsu, MD, Taro Yoshida, MD, Masayuki Imaya, MD, Ayako Yamamori, MD, Shunsuke Miwata, MD, Kotaro Narita, MD, Motoharu Hamada, MD PhD, Daisuke Ichikawa, MD, Rieko Taniguchi, MD, Nozomu Kawashima, MD PhD, Eri Nishikawa, MD PhD, Atsushi Narita, Nobuhiro Nishio, MD PhD, Seiji Kojima, MD PhD, Yoshiyuki Takahashi, MD PhD

Blood (2019) 134 (Supplement_1): 2973.

https://doi.org/10.1182/blood-2019-127792

Published: 2019

Journal Articles

Comprehensive Mutational Analysis of Juvenile Myelomonocytic Leukemia Using Whole-Genome Sequencing

Yusuke Okuno, MD PhD, Hideki Muramatsu, MD PhD, Norihiro Murakami, MD PhD, Nozomu Kawashima, MD, Manabu Wakamatsu, MD, Hironobu Kitazawa, Tomoo Ogi, PhD, Yoshiyuki Takahashi, MD PhD

Blood (2019) 134 (Supplement_1): 2974.

https://doi.org/10.1182/blood-2019-121681

Published: 2019

Journal Articles

Spectrum of Abnormalities and Clonal Transformation in Germline RUNX1 Familial Platelet Disorder and a Comparative Analysis with Somatic RUNX1 Mutations in Myeloid Neoplasms

Emma Difilippo, BS, Giacomo Coltro, MD, Ryan M. Carr, MD PhD, Abhishek A Mangaonkar, MBBS, Moritz Binder, MDMPH, Shakila P Khan, MD, Vilmarie Rodriguez, MD, Naseema Gangat, MBBS, Alexandra Wolanskyj, MD, Rajiv K. Pruthi, MBBS, Dong Chen, MD PhD, Rong He, MD, David S Viswanatha, MD, Terra Lasho, PhD, Christy Finke, BS, Ayalew Tefferi, MD, Animesh Pardanani, MBBS, PhD, Mark Litzow, MD, Mrinal M Patnaik, MDMBBS

Blood (2019) 134 (Supplement_1): 3003.

https://doi.org/10.1182/blood-2019-124830

Published: 2019

Journal Articles

Phenotypic Correlates and Prognostic Outcomes of TET2 Mutations in Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes: A Comprehensive Study of 504 Patients

Blood (2019) 134 (Supplement_1): 3005.

https://doi.org/10.1182/blood-2019-124115

Published: 2019

Journal Articles

SETBP1 Mutations Accelerate NRAS-Mutant Leukemia

Sarah A Carratt, PhD BS, Zachary Schonrock, BS, Theodore Braun, MD PhD, Cody Coblentz, Amy Foley, MEng., Julia E. Maxson, PhD

Blood (2019) 134 (Supplement_1): 1254.

https://doi.org/10.1182/blood-2019-125125

Published: 2019

Journal Articles

Investigation of New Therapeutic Compounds for Juvenile Myelomonocytic Leukemia Using Induced Pluripotent Stem Cells with Stably Activated Ras Pathway

Lisa Maria Kuhn, Cyrill Schipp, PhD, Daniel Hein, PhD, Bianca Killing, Nan Qin, PhD, Vera H Jepsen, M.Sc., Heinz Ahlert, MSc, BSc, Jasmin Bartl, PhD, Viktoria Marquardt, M.Sc., David Pauck, Kai Völtzke, M.Sc., Jonathan Lim, PhD, Gabriel Leprivier, PhD, Marc Remke, MD, Sanil Bhatia, PhD, Thorsten Rosenbaum, MD, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2019) 134 (Supplement_1): 4651.

https://doi.org/10.1182/blood-2019-131406

Published: 2019

Journal Articles

A Phase 1/2 Study of Quizartinib (Q) in Combination with Re-Induction Chemotherapy and As Single-Agent Continuation Therapy in Pediatric and Young Adult Patients with Relapsed/Refractory (R/R) FLT3 -ITD Acute Myeloid Leukemia (AML)

C. Michel Zwaan, MD PhD, Edward Anders Kolb, MD, Derek E. Mires, PharmD, Michele Vigliotti, PharmD, Jingdong Xie, PhD, Pamela Downs, BS, Arthur P DeCillis, MD MS, Cara A Rabik, MD PhD, Todd M Cooper, DO

Blood (2019) 134 (Supplement_1): 3937.

https://doi.org/10.1182/blood-2019-121736

Published: 2019

Journal Articles

Novel Improvement of Haploidentical Hematopoietic Stem Cell Transplantation for Advanced Refractory/Relapsed Acute Leukemia

Fei Pan, Peihua Lu, Zhijie Wei, Rong Yang, Shuquan Ji, MD

Blood (2019) 134 (Supplement_1): 4593.

https://doi.org/10.1182/blood-2019-127820

Published: 2019

Journal Articles

Azacitidine in Pediatric Hematologic Myeloid Malignancies: A Retrospective Study

Emilie Saucier, Florence Rabian, MD, Hélène Boutroux, MD, Marion Strullu, MD, Karine Morand, MD, Florian Chevillon, MD, Benoit Brethon, MD, Nicolas Boissel, MD PhD, Guy Leverger, MD, André Baruchel, MD

Blood (2019) 134 (Supplement_1): 5130.

https://doi.org/10.1182/blood-2019-131062

Published: 2019

Journal Articles

Detection of Subclonal SETBP1 and JAK3 Mutations in Patients with Juvenile Myelomonocytic Leukemia Using Droplet Digital PCR

Manabu Wakamatsu, MD, Hideki Muramatsu, MD PhD, Norihiro Murakami, MD PhD, Yusuke Okuno, MD PhD, Hironobu Kitazawa, Seiji Kojima, MD PhD, Yoshiyuki Takahashi, MD PhD

Blood (2019) 134 (Supplement_1): 4213.

https://doi.org/10.1182/blood-2019-125354

Published: 2019

Journal Articles

Complementary Transplantation with Unrelated Cord Blood Following Haploidentical Stem Cells for Juvenile Myelomonocytic Leukemia:Double-Centers Study from China

Zhiyong Peng, MD, Xiaoqin Feng, Huaying Liu, MD, Jianyun Liao, MD, Chaoke Bu, Yuelin He, MD, Jianmin Zhang, MD, Jingyu Gao, Chunfu Li, MD

Blood (2019) 134 (Supplement_1): 4181.

https://doi.org/10.1182/blood-2019-128331

Published: 2019

Journal Articles

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Pier Paolo Leoncini, PhD, Alessandro Domenico Silvestris, PhD, Patrizia Vitullo, PhD, Marco Zecca, MD, Christian Flotho, MD PhD, Charlotte M. Niemeyer, MD, Angela Gallo, PhD, Alice Bertaina, MD PhD, Franco Locatelli, MD PhD, Pietro Merli, MD

Blood (2019) 134 (Supplement_1): 4229.

https://doi.org/10.1182/blood-2019-129965

Published: 2019

Journal Articles

Improvement of Survival in JMML By Induction Regimen of Decitabine + Cytarabine + Fludarabine before Hematopoietic Stem Cell Transplantation: Study of 33 Cases in Single Center

Xiaoqin Feng, Zhiyong Peng, MD, Yuelin He, MD, Chunfu Li, MD, Yongsheng Ruan, MD, Xuan Liu, Rongfang Ding, MD, Wanxia Tan

Blood (2019) 134 (Supplement_1): 4267.

https://doi.org/10.1182/blood-2019-130488

Published: 2019

Journal Articles

Juvenile myelomonocytic leukemia: who’s the driver at the wheel?

Charlotte M. Niemeyer, Christian Flotho

Blood (2019) 133 (10): 1060–1070.

https://doi.org/10.1182/blood-2018-11-844688

Published: 2019

Journal Articles

Vitamin D Status in Children with Leukemia

Natalja Jackmann, MD, Arja H Harila-Saari, Outi Mäkitie, Jan Gustafsson, Dzeneta Nezirevich Dernroth, Per Frisk

Blood (2018) 132 (Supplement 1): 3973.

https://doi.org/10.1182/blood-2018-99-119557

Published: 2018

Journal Articles

Oncogenic KRAS G12D in the Hematopoietic System Causes NLRP3 Inflammasome Activation Leading to Myeloproliferative Syndrome

Shaima'A Hamarsheh, MSc, BSc, Miriam Erlacher, MD PhD, Lena Osswald, Oliver Gorka, PhD, Justus Duyster, Prof., Olaf Groß, PhD, Claudia Lengerke, MD, Melanie Börries, PhD, Tilman Brummer, PhD, Robert Zeiser, MD

Blood (2018) 132 (Supplement 1): 2618.

https://doi.org/10.1182/blood-2018-99-114161

Published: 2018

Journal Articles

Combined Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) and Phosphoinositide 3-Kinase (PI3K) p110δ Rescues Monocytosis, Thrombocytopenia, and Splenomegaly in a Genetic Mouse Model for JMML

Roshni Patel, BS, Baskar Ramdas, PhD, Lisa Deng, PhD, Victoria Jideonwo-Auman, PhD, Rebecca J Chan, MD PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 2623.

https://doi.org/10.1182/blood-2018-99-118802

Published: 2018

NARROW

DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation

Genomic Landscape of Juvenile Myelomonocytic Leukemia: A Real World Context

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Genome-Wide Methylation Analysis Using the Digital Restriction Enzyme Analysis of Methylation for Stratification of Patients with Juvenile Myelomonocytic Leukemia

Comprehensive Mutational Analysis of Juvenile Myelomonocytic Leukemia Using Whole-Genome Sequencing

Spectrum of Abnormalities and Clonal Transformation in Germline RUNX1 Familial Platelet Disorder and a Comparative Analysis with Somatic RUNX1 Mutations in Myeloid Neoplasms

Phenotypic Correlates and Prognostic Outcomes of TET2 Mutations in Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes: A Comprehensive Study of 504 Patients

SETBP1 Mutations Accelerate NRAS-Mutant Leukemia

Investigation of New Therapeutic Compounds for Juvenile Myelomonocytic Leukemia Using Induced Pluripotent Stem Cells with Stably Activated Ras Pathway

A Phase 1/2 Study of Quizartinib (Q) in Combination with Re-Induction Chemotherapy and As Single-Agent Continuation Therapy in Pediatric and Young Adult Patients with Relapsed/Refractory (R/R) FLT3 -ITD Acute Myeloid Leukemia (AML)

Novel Improvement of Haploidentical Hematopoietic Stem Cell Transplantation for Advanced Refractory/Relapsed Acute Leukemia

Azacitidine in Pediatric Hematologic Myeloid Malignancies: A Retrospective Study

Detection of Subclonal SETBP1 and JAK3 Mutations in Patients with Juvenile Myelomonocytic Leukemia Using Droplet Digital PCR

Complementary Transplantation with Unrelated Cord Blood Following Haploidentical Stem Cells for Juvenile Myelomonocytic Leukemia:Double-Centers Study from China

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Improvement of Survival in JMML By Induction Regimen of Decitabine + Cytarabine + Fludarabine before Hematopoietic Stem Cell Transplantation: Study of 33 Cases in Single Center

Juvenile myelomonocytic leukemia: who’s the driver at the wheel?

Vitamin D Status in Children with Leukemia

Oncogenic KRAS G12D in the Hematopoietic System Causes NLRP3 Inflammasome Activation Leading to Myeloproliferative Syndrome

Combined Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) and Phosphoinositide 3-Kinase (PI3K) p110δ Rescues Monocytosis, Thrombocytopenia, and Splenomegaly in a Genetic Mouse Model for JMML

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American Society of Hematology

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ASH Publications

American Society of Hematology

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