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Journal Articles

CRISPR-Cas9 Mediated CD45 Knockout Inactivates Src Family Kinases and Impairs Cell Migration in Multiple Myeloma

Wing Yu Man, BSc, Tiffany Khong, BSc, PhD, Andrew Spencer, MBBS, MD FRACP, FRCPA
Journal: Blood
Blood (2018) 132 (Supplement 1): 1907.
https://doi.org/10.1182/blood-2018-99-117532
Published: 2018
Journal Articles

Molecular Mechanism and Optimal Treatment Strategy in Acute Myeloid Leukemia with Resistance to Drugs and Radiation By NVP-LED225

Fanyi Meng, Xiaodong Li, Bingjie Ding, Kaikai Huang, Qiuhua Zhu, Fang Chen, Yufeng Zhu
Journal: Blood
Blood (2015) 126 (23): 3691.
https://doi.org/10.1182/blood.V126.23.3691.3691
Published: 2015
Journal Articles

Hh/IGF-1R/PI3K/Akt/MRP1 Pathway Induce Refractory Acute Myeloid Leukemia and Its Targeting Therpy

Kaikai Huang, Bingjie Ding, MD, Qingxiu Zhong, MD, Xuejie Jiang, MDPhD, Xiaodong Li, MD, Zhixiang Wang, MD, Fan Yi Meng, MD
Journal: Blood
Blood (2014) 124 (21): 3612.
https://doi.org/10.1182/blood.V124.21.3612.3612
Published: 2014
Journal Articles

Clathrin-Mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Lung Tumor Epithelial Cells

Alyssa D. Gregory, PhD, Pamela D. Hale, David H. Perlmutter, MD, Steven D. Shapiro, MD, A. McGarry Houghton, MD
Journal: Blood
Blood (2012) 120 (21): 3269.
https://doi.org/10.1182/blood.V120.21.3269.3269
Published: 2012
Journal Articles

Comprehensive in Vitro and in Vivo Analysis of Phosphatidylinositol-3-Kinase Delta (PI3Kδ) Inhibition Using GS-1101 (CAL-101) in Combination with Mammalian Target of Rapamycin (mTOR) Inhibition Using Temsirolimus or Everolimus in Mantle Cell Lymphoma (MCL)

Paul M. Barr, MD, Francisco J. Hernandez-Ilizaliturri, MD, Thomas Murante, BS, Shannon P. Hilchey, PhD, Derick R Peterson, PhD, Jennifer L. Kelly, PhD, MPH, Dave M. Johnson, Brian J. Lannutti, PhD, Myron S. Czuczman, MD, Jonathan W. Friedberg, MD, Steven H. Bernstein, MD
Journal: Blood
Blood (2012) 120 (21): 3719.
https://doi.org/10.1182/blood.V120.21.3719.3719
Published: 2012
Journal Articles

Knockdown of Insulin Receptor Substrate 1 (IRS1); a Partner of BCR-ABL, Results In Decrease In Proliferation and Downregulation of AKT/mTOR and MAPK Pathways In K562 Cells

Joao Machado-Neto, BSci, Patricia Favaro, Ph.D., Mariana Lazarini, PhD, Fernando Ferreira Costa, Ph.D., M.D., Sara T. Olalla-Saad, M.D., Ph.D., Fabiola Traina, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4459.
https://doi.org/10.1182/blood.V116.21.4459.4459
Published: 2010
Journal Articles

Induction of Insulin Resistance by Adipokines in Human Megakaryocytes

Anja J Gerrits, Eelo Gitz, Arnold C Koekman, Frank L Visseren, MD, PhD, Jan-Willem Akkerman, PhD
Journal: Blood
Blood (2008) 112 (11): 5390.
https://doi.org/10.1182/blood.V112.11.5390.5390
Published: 2008
Journal Articles

Identification of Novel Receptors on Myeloma Cells and Monocytes That Contribute to Myeloma Tumor Proliferation and Angiogenesis.

Melinda S. Gordon, PhD, Hee Jin Lee, BS, Richard A. Campbell, BS, Haiming Chen, MD, Ph.D, Benjamin Bonavida, PhD, James R. Berenson, MD
Journal: Blood
Blood (2005) 106 (11): 2507.
https://doi.org/10.1182/blood.V106.11.2507.2507
Published: 2005
Journal Articles

Studies on GM-CSF Induced Signaling and Cell Growth in JMML: An Experimental Model To Identify Mechanism Directed Targeted Therapeutics.

Yu Ding, MD, Bijan Teja, Chris Blackmore, Sumita Dingwa, Eva Ujack, Christopher Brown, MD, Aru Narendran, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2765.
https://doi.org/10.1182/blood.V106.11.2765.2765
Published: 2005
Journal Articles

Core Epo Receptor Signaling Circuits in Adult Bone Marrow-Derived Primary Pro-Erythroblasts.

Don M. Wojchowski, PhD, Madhu Menon, MD, Vinit Karur, MD, Bethany Vincent, BA
Journal: Blood
Blood (2004) 104 (11): 1621.
https://doi.org/10.1182/blood.V104.11.1621.1621
Published: 2004
Journal Articles

MTOR Inhibitors Activate the AKT Kinase in Multiple Myeloma Cells by Upregulating the IGF-1/IRS-1/PI-3 Kinase Cascade.

Yijiang Shi, Ph D, HuaJun Yan, Ph D, Patrick Frost, Ph D, Bao Hoang, Ph D, Joseph Gera, Ph D, Alan Lichtenstein, MD
Journal: Blood
Blood (2004) 104 (11): 3350.
https://doi.org/10.1182/blood.V104.11.3350.3350
Published: 2004
Journal Articles

The IRS-Pathway Operates Distinctively From the Stat-Pathway in Hematopoietic Cells and Transduces Common and Distinct Signals During Engagement of the Insulin or Interferon-α Receptors

Shahab Uddin, Eleanor N. Fish, Dorie Sher, Concetta Gardziola, Oscar R. Colamonici, Merrill Kellum, Paula M. Pitha, Morris F. White, Leonidas C. Platanias
Journal: Blood
Blood (1997) 90 (7): 2574–2582.
https://doi.org/10.1182/blood.V90.7.2574
Published: 1997