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Journal Articles

CRISPR-Cas9 Mediated CD45 Knockout Inactivates Src Family Kinases and Impairs Cell Migration in Multiple Myeloma

Wing Yu Man, BSc, Tiffany Khong, BSc, PhD, Andrew Spencer, MBBS, MD FRACP, FRCPA

Blood (2018) 132 (Supplement 1): 1907.

https://doi.org/10.1182/blood-2018-99-117532

Published: 2018

Journal Articles

Molecular Mechanism and Optimal Treatment Strategy in Acute Myeloid Leukemia with Resistance to Drugs and Radiation By NVP-LED225

Fanyi Meng, Xiaodong Li, Bingjie Ding, Kaikai Huang, Qiuhua Zhu, Fang Chen, Yufeng Zhu

Blood (2015) 126 (23): 3691.

https://doi.org/10.1182/blood.V126.23.3691.3691

Published: 2015

Journal Articles

Hh/IGF-1R/PI3K/Akt/MRP1 Pathway Induce Refractory Acute Myeloid Leukemia and Its Targeting Therpy

Kaikai Huang, Bingjie Ding, MD, Qingxiu Zhong, MD, Xuejie Jiang, MDPhD, Xiaodong Li, MD, Zhixiang Wang, MD, Fan Yi Meng, MD

Blood (2014) 124 (21): 3612.

https://doi.org/10.1182/blood.V124.21.3612.3612

Published: 2014

Journal Articles

Clathrin-Mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Lung Tumor Epithelial Cells

Alyssa D. Gregory, PhD, Pamela D. Hale, David H. Perlmutter, MD, Steven D. Shapiro, MD, A. McGarry Houghton, MD

Blood (2012) 120 (21): 3269.

https://doi.org/10.1182/blood.V120.21.3269.3269

Published: 2012

Journal Articles

Comprehensive in Vitro and in Vivo Analysis of Phosphatidylinositol-3-Kinase Delta (PI3Kδ) Inhibition Using GS-1101 (CAL-101) in Combination with Mammalian Target of Rapamycin (mTOR) Inhibition Using Temsirolimus or Everolimus in Mantle Cell Lymphoma (MCL)

Paul M. Barr, MD, Francisco J. Hernandez-Ilizaliturri, MD, Thomas Murante, BS, Shannon P. Hilchey, PhD, Derick R Peterson, PhD, Jennifer L. Kelly, PhD, MPH, Dave M. Johnson, Brian J. Lannutti, PhD, Myron S. Czuczman, MD, Jonathan W. Friedberg, MD, Steven H. Bernstein, MD

Blood (2012) 120 (21): 3719.

https://doi.org/10.1182/blood.V120.21.3719.3719

Published: 2012

Journal Articles

Knockdown of Insulin Receptor Substrate 1 (IRS1); a Partner of BCR-ABL, Results In Decrease In Proliferation and Downregulation of AKT/mTOR and MAPK Pathways In K562 Cells

Joao Machado-Neto, BSci, Patricia Favaro, Ph.D., Mariana Lazarini, PhD, Fernando Ferreira Costa, Ph.D., M.D., Sara T. Olalla-Saad, M.D., Ph.D., Fabiola Traina, MD, PhD

Blood (2010) 116 (21): 4459.

https://doi.org/10.1182/blood.V116.21.4459.4459

Published: 2010

Journal Articles

Induction of Insulin Resistance by Adipokines in Human Megakaryocytes

Anja J Gerrits, Eelo Gitz, Arnold C Koekman, Frank L Visseren, MD, PhD, Jan-Willem Akkerman, PhD

Blood (2008) 112 (11): 5390.

https://doi.org/10.1182/blood.V112.11.5390.5390

Published: 2008

Journal Articles

Identification of Novel Receptors on Myeloma Cells and Monocytes That Contribute to Myeloma Tumor Proliferation and Angiogenesis.

Melinda S. Gordon, PhD, Hee Jin Lee, BS, Richard A. Campbell, BS, Haiming Chen, MD, Ph.D, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2005) 106 (11): 2507.

https://doi.org/10.1182/blood.V106.11.2507.2507

Published: 2005

Journal Articles

Studies on GM-CSF Induced Signaling and Cell Growth in JMML: An Experimental Model To Identify Mechanism Directed Targeted Therapeutics.

Yu Ding, MD, Bijan Teja, Chris Blackmore, Sumita Dingwa, Eva Ujack, Christopher Brown, MD, Aru Narendran, MD, PhD

Blood (2005) 106 (11): 2765.

https://doi.org/10.1182/blood.V106.11.2765.2765

Published: 2005

Journal Articles

MTOR Inhibitors Activate the AKT Kinase in Multiple Myeloma Cells by Upregulating the IGF-1/IRS-1/PI-3 Kinase Cascade.

Yijiang Shi, Ph D, HuaJun Yan, Ph D, Patrick Frost, Ph D, Bao Hoang, Ph D, Joseph Gera, Ph D, Alan Lichtenstein, MD

Blood (2004) 104 (11): 3350.

https://doi.org/10.1182/blood.V104.11.3350.3350

Published: 2004

Journal Articles

Core Epo Receptor Signaling Circuits in Adult Bone Marrow-Derived Primary Pro-Erythroblasts.

Don M. Wojchowski, PhD, Madhu Menon, MD, Vinit Karur, MD, Bethany Vincent, BA

Blood (2004) 104 (11): 1621.

https://doi.org/10.1182/blood.V104.11.1621.1621

Published: 2004

Journal Articles

The IRS-Pathway Operates Distinctively From the Stat-Pathway in Hematopoietic Cells and Transduces Common and Distinct Signals During Engagement of the Insulin or Interferon-α Receptors

Shahab Uddin, Eleanor N. Fish, Dorie Sher, Concetta Gardziola, Oscar R. Colamonici, Merrill Kellum, Paula M. Pitha, Morris F. White, Leonidas C. Platanias

Blood (1997) 90 (7): 2574–2582.

https://doi.org/10.1182/blood.V90.7.2574

Published: 1997

NARROW

CRISPR-Cas9 Mediated CD45 Knockout Inactivates Src Family Kinases and Impairs Cell Migration in Multiple Myeloma

Molecular Mechanism and Optimal Treatment Strategy in Acute Myeloid Leukemia with Resistance to Drugs and Radiation By NVP-LED225

Hh/IGF-1R/PI3K/Akt/MRP1 Pathway Induce Refractory Acute Myeloid Leukemia and Its Targeting Therpy

Clathrin-Mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Lung Tumor Epithelial Cells

Comprehensive in Vitro and in Vivo Analysis of Phosphatidylinositol-3-Kinase Delta (PI3Kδ) Inhibition Using GS-1101 (CAL-101) in Combination with Mammalian Target of Rapamycin (mTOR) Inhibition Using Temsirolimus or Everolimus in Mantle Cell Lymphoma (MCL)

Knockdown of Insulin Receptor Substrate 1 (IRS1); a Partner of BCR-ABL, Results In Decrease In Proliferation and Downregulation of AKT/mTOR and MAPK Pathways In K562 Cells

Induction of Insulin Resistance by Adipokines in Human Megakaryocytes

Identification of Novel Receptors on Myeloma Cells and Monocytes That Contribute to Myeloma Tumor Proliferation and Angiogenesis.

Studies on GM-CSF Induced Signaling and Cell Growth in JMML: An Experimental Model To Identify Mechanism Directed Targeted Therapeutics.

MTOR Inhibitors Activate the AKT Kinase in Multiple Myeloma Cells by Upregulating the IGF-1/IRS-1/PI-3 Kinase Cascade.

Core Epo Receptor Signaling Circuits in Adult Bone Marrow-Derived Primary Pro-Erythroblasts.

The IRS-Pathway Operates Distinctively From the Stat-Pathway in Hematopoietic Cells and Transduces Common and Distinct Signals During Engagement of the Insulin or Interferon-α Receptors

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American Society of Hematology

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ASH Publications

American Society of Hematology

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