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Journal Articles

Seven Cases of JAK2 Mutation Negative Chronic Polycythemia Patients with Elevated IGF-1R

Guanfang Shi, PhD, Rewais Morcus, MD, Maksim Liaukovich, MD, Ching Wong, MD, Vladimir Gotlieb, Jen-Chin Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5389.
https://doi.org/10.1182/blood-2019-123006
Published: 2019
Journal Articles

A Strong Correlation of the HIF1a mRNA Expression Level with the Total Expression of JAK2, As Well As a Decrease in Their Level Is Observed in Leukocytes of Patients with MPN and Lymphoproliferative Cancer

Igor A. Olkhovskiy, Aleksey S. Gorbenko, Marina A. Stolyar, Anna V. Komina, Evgeniy V. Vasiliev, Mikhail A. Mikhalev, Tatiana I. Olkhovik, Varvara I. Bakhtina
Journal: Blood
Blood (2019) 134 (Supplement_1): 5032.
https://doi.org/10.1182/blood-2019-122086
Published: 2019
Journal Articles

HIF-1a Regulating the Chemoresistance By Upregulating the Expression of xCT and GCLM in the Diffuse Large B Cell Lymphoma

Yongqiang Wei, PhD, Hong Zeng, Xiaolei Wei, PhD, Weimin Huang, PhD, Jialin Song, Jingxia Zheng, Ru Feng, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5236.
https://doi.org/10.1182/blood-2019-127612
Published: 2019
Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3718.
https://doi.org/10.1182/blood-2019-131124
Published: 2019
Journal Articles

Myelodysplastic Syndromes-Associated Gene Mutations Lead to Pseudohypoxia Condition and Epigenome Hyper-Methylation in Mouse Genetic Models

Asumi Yokota, PhD, Lulu Zhang, PhD, Jianhua Feng, Xiaomin Feng, MD PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1696.
https://doi.org/10.1182/blood-2019-126799
Published: 2019
Journal Articles

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Xiaoyang Su, PhD, Ying Chen, PhD, Maisarah Mokhtar, B.S, Gregory Dolnikowski, Frederick Lansigan, MD, William B Kinlaw, III, MD, Sandeep Dave, MD, Andrew M. Evens, DO, MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1573.
https://doi.org/10.1182/blood-2019-126382
Published: 2019
Journal Articles

Unravelling the Heterogeneity of Mantle Cell Lymphoma Ecosystem By Single Cell RNA Sequencing

Makhdum Ahmed, MD PhD MPH, Hui Guo, PhD, Shaojun Zhang, PhD, Lalit Sehgal, PhD MPhil, Preetesh Jain, MBBS, MDDM, PhD, Rashmi Kanagal-Shamanna, MD, Chi Young Ok, MD, Angela Leeming, Yixin Yao, PhD, Liang Zhang, MD PhD, Krystle Nomie, PhD, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4118.
https://doi.org/10.1182/blood-2018-99-110540
Published: 2018
Journal Articles

Mechanism of Synergistic Effects on T Cell Activation By Avadomide (CC-122) and Nivolumab

Yumi Nakayama, PhD, Matthew E. Stokes, PhD, Michelle Waldman, MS, Patrick R. Hagner, PhD, Anita K. Gandhi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4133.
https://doi.org/10.1182/blood-2018-99-114469
Published: 2018
Journal Articles

A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3 - PBX1 B-ALL

Ruth E Cranston, BSc, Paul B Sinclair, PhD, Matthew Bashton, PhD, Matthew P Selby, PhD, Christine J Harrison, PhD FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 3915.
https://doi.org/10.1182/blood-2018-99-110015
Published: 2018
Journal Articles

Mll -Partial Tandem Duplication ( Mll -PTD) Causes Pseudohypoxia and Hypermethylation of the Epigenome through Suppression of Mitochondrial Complex II

Asumi Yokota, PhD, Lulu Zhang, PhD, Xiaomei Yan, MD PhD, Xiaomin Feng, MD PhD, Lijun Wen, MS, George Freudiger, Maria Rife, Ally Woeste, Yoshihiro Hayashi, MD PhD, Gang Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1311.
https://doi.org/10.1182/blood-2018-99-112529
Published: 2018
Journal Articles

Targeting of Glutamine Pathways Restores Sensitivity in Venetoclax Resistant Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Jessica T Leonard, MD, Bill H. Chang, MD PhD, Jeffrey W. Tyner, PhD, Brian J. Druker, MD, Marc Loriaux, MD PhD, Pavani Malla, MS
Journal: Blood
Blood (2017) 130 (Supplement 1): 1264.
https://doi.org/10.1182/blood.V130.Suppl_1.1264.1264
Published: 2017
Journal Articles

Sepsis Induced Red Cell Dysfunction (SiRD): Physiology and Mechanisms

Xue Lin, MD PhD, Stephen Rogers, PhD, David Timm, MS, d'Alessandro Angelo, PhD, Prakash Jaya, Ernst Melanie, BS, Julie Prior, PhD, Shah Shivam, PhD, Jackie Wu, Julie Reisz, PhD, Allan Doctor, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3469.
https://doi.org/10.1182/blood.V130.Suppl_1.3469.3469
Published: 2017
Journal Articles

Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice

Shin-Young Park, PhD, Alessandro Mattè, PhD, Eun Young Anna Han, B.S., Min Liu, M.S., Jina Ryu, PhD, Lucia De Franceschi, MD, Leslie E. Silberstein, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3522.
https://doi.org/10.1182/blood.V130.Suppl_1.3522.3522
Published: 2017
Journal Articles

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Yoshihiro Hayashi, MD PhD, Rui Huang, MD PhD, Xiaomei Yan, Jiachen BU, PhD, Jieyu Wang, MD PhD, Yue Zhang, MD PhD, Yile Zhou, MD, Yuting Tang, MD, Lingyun Wu, MD PhD, Zefeng Xu, MD, Xin Liu, MD PhD, Qianfei Wang, PhD, Jianfeng Zhou, Zhijian Xiao, James P Bridges, PhD, Rebecca A Marsh, Kejian Zhang, MD MBA, Michael B. Jordan, MD, Yuhua Li, MD, Gang Huang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3565.
https://doi.org/10.1182/blood.V130.Suppl_1.3565.3565
Published: 2017
Journal Articles

Adenosine Signaling Regulates Erythroid Commitment Via Modulation of Metabolic Reprogramming in Stress Erythropoiesis

Liu Hong, MD PhD, Travis Nemkov, Rongrong Liu, Jacob Couturier, PhD, Ye Youqiong, PhD, Angelo D'Alessandro, PhD, Anren Song, PhD, Shushan Zhao, MD PhD, Kaiqi Sun, PhD, Adebiyi Morayo, Yuan Edward Wen, Alexander Wen, Hansen Kirk C., PhD, Leng Han, PhD, Dorothy E. Lewis, PhD, Xian Wa, PhD, Holger K. Eltzschig, MD PhD, Michael Blackburn, PhD, Rodney Kellems, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1156.
https://doi.org/10.1182/blood.V130.Suppl_1.1156.1156
Published: 2017
Journal Articles

Integrative Epigenetic and Single-Cell RNA-Seq Profiling of Human Hematopoietic Stem Cells Reveals Epigenetic Reprogramming of Enhancer and Regulatory Elements during Normal Aging

Emmalee Adelman, BA, André Olsson, MSc, PhD, Tingting Qin, PhD, R. Coleman Lindsley, MD PhD, Rafael Bejar, MD PhD, Nathan Salomonis, PhD, Lee Grimes, Maria E. Figueroa, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 770.
https://doi.org/10.1182/blood.V130.Suppl_1.770.770
Published: 2017
Journal Articles

Hypoxia-Inducible KDM3A Addiction in Multiple Myeloma

Sho Ikeda, MD, Akihiro Kitadate, MD, Fumito Abe, MD PhD, Naoto Takahashi, Hiroyuki Tagawa, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3061.
https://doi.org/10.1182/blood.V130.Suppl_1.3061.3061
Published: 2017
Journal Articles

Computational Biology Approach to Predict Hypomethylating Agent (HMA) Response Using Genomic and Clinical Characteristics in Myelodsyplastic Syndromes (MDS)

Leylah M. Drusbosky, PhD, Salah-Eddin Komrokji, Najla Al Ali, M.Sc, Neeraj Kumar Singh, B.Tech, Chandan Kumar, MT, Sumanth Vasista, BE, Diwyanshu Sahu, M.Sc., Ganesh Naga, BT, Patil Dattatraya, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, David A Sallman, MD, Rami S. Komrokji, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2954.
https://doi.org/10.1182/blood.V130.Suppl_1.2954.2954
Published: 2017
Journal Articles

Computational Biology Model of ETP-ALL Used to Accurately Classify ETP-ALL Vs Non ETP-ALL Patients with Genomic Input

Leylah M. Drusbosky, PhD, Ansu Kumar, MS, Shwetha K, BE, Sumanth Vasista, BE, Anuj Tyagi, MS, Swaminathan Rajagopalan, MT, Aftab Alam, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Girish Chinnaswamy, MD MRCP, Manju Sengar, MD DM, Bijal D. Shah, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1449.
https://doi.org/10.1182/blood.V130.Suppl_1.1449.1449
Published: 2017
Journal Articles

Identification and Molecular Characterization of Endothelial Cells Associated with Hematopoietic Niche Formation in Humans Identifies IL-33 As an Anabolic Niche Factor

Keane Jared Guillaume Kenswil, BSc, MSc, Christopher Adrian Jaramillo, MD, Zhen Ping, MSc, Si Chen, MSc, Remco Michiel Hoogenboezem, MSc, Maria Athina Mylona, PhD, Maria Niken Adisty, BSc, Eric Moniqué Johannes Bindels, PhD, Hans Stoop, PhD, King Hong Lam, MD PhD, Pieter Koen Bos, MD, Bram van Eerden, PhD, Tom Cupedo, PhD, Marc Hermanus Gerardus Petrus Raaijmakers, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2437.
https://doi.org/10.1182/blood.V130.Suppl_1.2437.2437
Published: 2017