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Journal Articles

Comparison of the Profile of the AML Drug Midostaurin (Rydapt®) As a Kinase Inhibitor with Those of Its Predominant Primary Human Metabolites

Paul W Manley, Giorgio Caravatti, Pascal Furet, Johannes Roesel, Phi Tran, Trixie Wagner

Blood (2017) 130 (Supplement 1): 1383.

https://doi.org/10.1182/blood.V130.Suppl_1.1383.1383

Published: 2017

Journal Articles

Pharmacokinetics of Treosulfan in Patients with Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation — a Comparison of Two Formulations and Correlation with Clinical Outcomes

Alok Srivastava, MD, Ezhilpavai Mohanan, Msc, Raveen Stephen Stallon Illangeswaran, M.Sc.,, Carl Panetta, PhD, Kavitha M Lakshmi, MSc, Anu Korula, MD DM, Aby Abraham, MD DM, Biju George, MDDM, Vikram Mathews, MD DM, Poonkuzhali Balasubramanian, MSc, PhD

Blood (2017) 130 (Supplement 1): 3219.

https://doi.org/10.1182/blood.V130.Suppl_1.3219.3219

Published: 2017

Journal Articles

Vitamin K5 Is an Efficient Photosensitizer for Ultraviolet a Light Inactivation of Bacteria

Fei Xu, Ying Li, Justen Jones, Jaroslav Vostal

Blood (2017) 130 (Supplement 1): 3744.

https://doi.org/10.1182/blood.V130.Suppl_1.3744.3744

Published: 2017

Journal Articles

Vitamin D Repletion Mitigates Oxidative Stress Induced Pulmonary Artery Remodeling in Sickle Cell Disease

Julia Brittain, PhD, E. Leila Jerome Clay, MD, Ryan Harris, PhD CEP, FACSM, Itia Lee, BS, Abdullah Kutlar, MD, Sanjiv Kumar, PhD

Blood (2017) 130 (Supplement 1): 443.

https://doi.org/10.1182/blood.V130.Suppl_1.443.443

Published: 2017

Journal Articles

Dose-Adjusted EPOCH Chemotherapy for Untreated Peripheral T-Cell Lymphomas: Multicenter Phase II Trial of West-Jhog PTCL0707

Yoshinobu Maeda, MD PhD, Hisakazu Nishimori, MD PhD, Yasushi Hiramatsu, Isao Yoshida, Masatoshi Uno, Yasufumi Masaki, MD PhD, Kazutaka Sunami, MD PhD, Taro Masunari, Yuichiro Nawa, Hiroshi Gomyo, Hiromichi Yamane, Tsutomu Takahashi, MD PhD, Tomofumi Yano, Hidetaka Takimoto, MD, Keitaro Matsuo, MD PhD, Tadashi Yoshino, MD PhD, Mitsune Tanimoto, MD PhD

Blood (2016) 128 (22): 5349.

https://doi.org/10.1182/blood.V128.22.5349.5349

Published: 2016

Journal Articles

Komaroviquinone-Derivatives, Revealed Anti-Tumor Effect on High-Risk Multiple Myeloma Cells In Vitro as Well as In Vivo

Mariko Sato, Kota Fujimori, Shotaro Kitabatake, Mikio Okayama, MD, Daiju Ichikawa, PhD, Yutaka Suto, PhD, Genji Iwasaki, PhD, Fumiyuki Kiuchi, PhD, Takashi Yamaguchi, Arimi Ueda, Shuji Aida, Hitomi Nakayama, MD, Maiko Matsushita, MD PhD, Yutaka Hattori, MD PhD

Blood (2016) 128 (22): 2100.

https://doi.org/10.1182/blood.V128.22.2100.2100

Published: 2016

Journal Articles

Oxidatively Modified Serotransferrin in Refractory Anemia with Ring Sideroblasts

Alzbeta Hlavackova, PhD, MSc., Jana Stikarova, PhD, MSc., Jiri Suttnar, PhD, MSc., Roman Kotlin, PhD, MSc., Pavel Majek, PhD, MSc., Leona Chrastinova, PhD, MSc., Ondrej Pastva, MSc, Jaroslav Cermak, MD PhD, Jan E. Dyr, prof., PhD, MSc., DSc.

Blood (2016) 128 (22): 5502.

https://doi.org/10.1182/blood.V128.22.5502.5502

Published: 2016

Journal Articles

Bioactive Lipids Are Generated to Micromolar Levels during RBC Storage, Even in Leukoreduced Units

Xiaoyun Fu, PhD, Jacob R. Felcyn, BS, James C. Zimring, MD PhD

Blood (2015) 126 (23): 2344.

https://doi.org/10.1182/blood.V126.23.2344.2344

Published: 2015

Journal Articles

Characterization of snoRNA Expression in Acute Myeloid Leukemia

Wayne A. Warner, BS, David Spencer, MDPhD, Maria Trissal, BS, Nichole Helton, BS, Timothy J. Ley, MD, Daniel C. Link, MD

Blood (2015) 126 (23): 3649.

https://doi.org/10.1182/blood.V126.23.3649.3649

Published: 2015

Journal Articles

Elevated Basal Autophagy in SF3B1 Mutated Myelodysplastic Syndromes: Relationship with Survival Outcomes and Therapeutic Implications

Valeria Visconte, PhD, Kevin R. Kelly, MD PhD, Steffan T. Nawrocki, PhD, Yingchun Han, MD, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Jaroslaw P. Maciejewski, MD PhD, Heesun J Rogers, MD PhD, Mikkael A. Sekeres, MD MS, Jennifer S. Carew, PhD

Blood (2015) 126 (23): 1647.

https://doi.org/10.1182/blood.V126.23.1647.1647

Published: 2015

Journal Articles

Establishing Modified Human CYP4B1 As a Novel Suicide Gene System for Adoptive T-Cell Therapies

Katharina Roellecke, M.Sc., Constanze Wiek, PhD, Christof Kramm, MD, Allan Rettie, PhD, Helmut Hanenberg, MD

Blood (2015) 126 (23): 5550.

https://doi.org/10.1182/blood.V126.23.5550.5550

Published: 2015

Journal Articles

Combination Mitigators, GS-Nitroxide JP4-039 and water Soluble Oxetanyl Sulfoxide MMS350 Improve Survival of Lethally Irradiated Mice

Michael W. Epperly, Tracy M. Dixon, Siping He, Donna Shields, Peter Wipf, Song Li, Joel S. Greenberger, MD

Blood (2014) 124 (21): 2751.

https://doi.org/10.1182/blood.V124.21.2751.2751

Published: 2014

Journal Articles

Sulfolane (a metabolite of busulfan) Levels Could Predict Occurrence Of Hemorrhagic Cystitis In Children Receiving Busulfan Based Myeloablative Conditioning Before Hematopoietic Stem Cell Transplantation

Chakradhara Rao S Uppugunduri, Mohamed Aziz Rezgui, Yves Theoret, Patricia Huezo Diaz, PhD, Anuj Kumar Tyagi, PHD, Samira Mezziani, Marie-France Vachon, Catherine Desjean, Michel Duval, MD, Henrique Bittencourt, MD, Maja Krajinovic, MD, PhD, Marc Ansari, MD

Blood (2013) 122 (21): 4574.

https://doi.org/10.1182/blood.V122.21.4574.4574

Published: 2013

Journal Articles

Clinical and Preclinical Characterisation Of The Metabolites Of The BCR-ABL Tyrosine Kinase Inhibitor Nilotinib

Paul W. Manley, Ph. D., Jürgen Mestan, Ph D, Jennifer Sheng, Ph D, Phi Tran, M Sc, Mark Kagan, Ph D

Blood (2013) 122 (21): 4011.

https://doi.org/10.1182/blood.V122.21.4011.4011

Published: 2013

Journal Articles

A-Type Proanthocyanidins Prevent Engraftment Of Primary Acute Myelogenous Leukemia Cells In Mice and Exhibit Potentially Novel Anti-Leukemia Mechanisms

Laura M Bystrom, PhD, Hongliang Zong, MD, PhD, Hsiao-Ting Hsu, MS, Neng Yang, MD, PhD, Noa Greenberg, MD, Qinghao Wang, MD, PhD, Catherine Neto, PhD, Maolin Guo, PhD, Stefano Rivella, PhD, Monica L. Guzman, PhD

Blood (2013) 122 (21): 3962.

https://doi.org/10.1182/blood.V122.21.3962.3962

Published: 2013

Journal Articles

Iron Chelation Therapy Could Rapidly Reduce Oxidative DNA Damage In CD34+ Hematopoietic Cells Before Decrease Of Serum Ferritin Level

Masayoshi Kobune, MD, PhD, Shohei Kikuchi, MD, PhD, Satoshi Iyama, MD, PhD, Kohichi Takada, MD, PhD, Kazuyuki Murase, MD, PhD, Kaoru Ono, MD, Hiroto Horiguchi, MD, Yusuke Kamihara, MD, Akari Hashimoto, MD, Ayumi Tatekoshi, MD, Tsuyoshi Hayashi, MD, PhD, Tsutomu Sato, MD, PhD, Koji Miyanishi, MD, PhD, Yasushi Sato, MD, PhD, Rishu Takimoto, MD, PhD, Junji Kato, MD, PhD

Blood (2013) 122 (21): 959.

https://doi.org/10.1182/blood.V122.21.959.959

Published: 2013

Journal Articles

The Diterpenoid Lactone Andrographolide Induces Reactive Oxygen Species (ROS) Dependent Apoptosis in ATRA Sensitive and Resistant APL Cell Lines.

Shuo Yang, PhD, Jessica K. Altman, MD, Sheila Prachand, MS, Austin Tom, BS, Bo Ding, BS, Brent Wu, Leonidas C. Platanias, MD, PhD, Leo I. Gordon, MD

Blood (2012) 120 (21): 2446.

https://doi.org/10.1182/blood.V120.21.2446.2446

Published: 2012

Journal Articles

The Proteasomal Inhibitor Clioquinol Induces Apoptosis in Leukemia and Myeloma Cells by Inhibiting Histone Deacetylase Activity.

Biyin Cao, MD, PhD, Mingyun Shen, Mr., Depei Wu, Jianhong Du, MD, Jingyu Zhu, Suning Chen, Aining Sun, Xiaowen Tang, MD, PhD, Zhuan Xu, Yan Kong, MD. PhD, Xinliang Mao, MD, PhD

Blood (2012) 120 (21): 2449.

https://doi.org/10.1182/blood.V120.21.2449.2449

Published: 2012

Journal Articles

Skeletal-Targeted, Osteolytic-Responsive Drug Delivery System Improves Anti-Tumor Efficacy in Multiple Myeloma.

Xuli Wang, PhD, Ye Yang, PhD, Scott Miller, PhD, Fenghuang Zhan, MD, PhD

Blood (2012) 120 (21): 3155.

https://doi.org/10.1182/blood.V120.21.3155.3155

Published: 2012

Journal Articles

Mapping the Location of Autoinhibitory B-Domain Motifs within Factor V: New Insights Into How Factor V Activation Unfolds

Raffaella Toso, PhD, Matthew W. Bunce, PhD, Rodney M. Camire, PhD

Blood (2012) 120 (21): 495.

https://doi.org/10.1182/blood.V120.21.495.495

Published: 2012

NARROW

Comparison of the Profile of the AML Drug Midostaurin (Rydapt®) As a Kinase Inhibitor with Those of Its Predominant Primary Human Metabolites

Pharmacokinetics of Treosulfan in Patients with Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation — a Comparison of Two Formulations and Correlation with Clinical Outcomes

Vitamin K5 Is an Efficient Photosensitizer for Ultraviolet a Light Inactivation of Bacteria

Vitamin D Repletion Mitigates Oxidative Stress Induced Pulmonary Artery Remodeling in Sickle Cell Disease

Dose-Adjusted EPOCH Chemotherapy for Untreated Peripheral T-Cell Lymphomas: Multicenter Phase II Trial of West-Jhog PTCL0707

Komaroviquinone-Derivatives, Revealed Anti-Tumor Effect on High-Risk Multiple Myeloma Cells In Vitro as Well as In Vivo

Oxidatively Modified Serotransferrin in Refractory Anemia with Ring Sideroblasts

Bioactive Lipids Are Generated to Micromolar Levels during RBC Storage, Even in Leukoreduced Units

Characterization of snoRNA Expression in Acute Myeloid Leukemia

Elevated Basal Autophagy in SF3B1 Mutated Myelodysplastic Syndromes: Relationship with Survival Outcomes and Therapeutic Implications

Establishing Modified Human CYP4B1 As a Novel Suicide Gene System for Adoptive T-Cell Therapies

Combination Mitigators, GS-Nitroxide JP4-039 and water Soluble Oxetanyl Sulfoxide MMS350 Improve Survival of Lethally Irradiated Mice

Sulfolane (a metabolite of busulfan) Levels Could Predict Occurrence Of Hemorrhagic Cystitis In Children Receiving Busulfan Based Myeloablative Conditioning Before Hematopoietic Stem Cell Transplantation

Clinical and Preclinical Characterisation Of The Metabolites Of The BCR-ABL Tyrosine Kinase Inhibitor Nilotinib

A-Type Proanthocyanidins Prevent Engraftment Of Primary Acute Myelogenous Leukemia Cells In Mice and Exhibit Potentially Novel Anti-Leukemia Mechanisms

Iron Chelation Therapy Could Rapidly Reduce Oxidative DNA Damage In CD34+ Hematopoietic Cells Before Decrease Of Serum Ferritin Level

The Diterpenoid Lactone Andrographolide Induces Reactive Oxygen Species (ROS) Dependent Apoptosis in ATRA Sensitive and Resistant APL Cell Lines.

The Proteasomal Inhibitor Clioquinol Induces Apoptosis in Leukemia and Myeloma Cells by Inhibiting Histone Deacetylase Activity.

Skeletal-Targeted, Osteolytic-Responsive Drug Delivery System Improves Anti-Tumor Efficacy in Multiple Myeloma.

Mapping the Location of Autoinhibitory B-Domain Motifs within Factor V: New Insights Into How Factor V Activation Unfolds

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American Society of Hematology

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ASH Publications

American Society of Hematology

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