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Journal Articles

Mutations and Copy Number Gains of the BCL2 Family Members Mediate Resistance to Venetoclax in Multiple Myeloma (MM) Patients

Paola Neri, MD PhD, Ranjan Maity, PhD, Jean-Baptiste Alberge, Sarthak Sinha, BSc, Justin Donovan, Madison Kong, Fajer Hasan, Arzina Jaffer, Lawrence H. Boise, PhD, Nizar Bahlis, MD

Blood (2019) 134 (Supplement_1): 572.

https://doi.org/10.1182/blood-2019-127593

Published: 2019

Journal Articles

Structural Basis of Vitamin K Antagonism

Weikai Li, PhD, Shixuan Liu, Shuang Li

Blood (2019) 134 (Supplement_1): 482.

https://doi.org/10.1182/blood-2019-127324

Published: 2019

Journal Articles

Functional Interactions between Transcription Factors Involved in Myeloma Pathogenesis - Biological and Therapeutic Implications

Sondra L. Downey-Kopyscinski, PhD, Ricardo De Matos Simoes, PhD, Ryosuke Shirasaki, MD, Huihui Tang, PhD, Brian Glassner, PhD, Olga Dashevsky, PhD, Minasri Borah, Megan Bariteau, B.Sc., Richard Groen, John G Doench, PhD, Constantine S. Mitsiades, MD PhD

Blood (2019) 134 (Supplement_1): 315.

https://doi.org/10.1182/blood-2019-127502

Published: 2019

Journal Articles

Identification of a Heme Activation Site on the MD-2/TLR4 Complex

John D Belcher, PhD, Ping Zhang, PhD, Julia Nguyen, Zachary Monroe Kiser, BS, PhD, John O Trent, PhD, Gregory M Vercellotti, MD

Blood (2019) 134 (Supplement_1): 209.

https://doi.org/10.1182/blood-2019-123788

Published: 2019

Journal Articles

Interactome Analysis of APOBEC3B in Multiple Myeloma

Yasuhiro Kazuma, MD, Kotaro Shirakawa, MD PhD, Anamaria Daniela Sarca, MD, Yoshihito Horisawa, MD, Hirofumi Fukuda, MD, Hiroyuki Matsui, MD, Hiroyuki Yamazaki, MD, Tadahiko Matsumoto, MD, Fumiko Tanabe, Ryo Morishita, PhD, Shinji Ito, PhD, Akifumi Takaori-Kondo, MD PhD

Blood (2019) 134 (Supplement_1): 1259.

https://doi.org/10.1182/blood-2019-126856

Published: 2019

Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD

Blood (2019) 134 (Supplement_1): 2962.

https://doi.org/10.1182/blood-2019-129234

Published: 2019

Journal Articles

NOTCH2 Contributes to Venetoclax Resistance in Chronic Lymphocytic Leukemia

Stefania Fiorcari, PhD, Rossana Maffei, PhD, Claudio Giacinto Atene, PhD, Silvia Martinelli, Leonardo Potenza, Mario Luppi, MD, Roberto Marasca, MD

Blood (2019) 134 (Supplement_1): 4280.

https://doi.org/10.1182/blood-2019-128499

Published: 2019

Journal Articles

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

Lauren K. Meyer, Cristina Delgado-Martin, PhD, Phillip P. Sharp, PhD, Dustin McMinn, PhD, Christopher J. Kirk, PhD, Jack Taunton, PhD, Michelle L. Hermiston, MD PhD

Blood (2019) 134 (Supplement_1): 805.

https://doi.org/10.1182/blood-2019-127537

Published: 2019

Journal Articles

GDF1 Is a Regulator of Sphingolipid Metabolism in Acute Myeloid Leukemia

Weiyuan Wang, Emily Sullivan, Vasiliki Papakotsi, Andrea Cote, Paul Toran, PhD, Thomas P Loughran, Jr., MD, Brian Barth, PhD MS, BS

Blood (2019) 134 (Supplement_1): 1245.

https://doi.org/10.1182/blood-2019-130964

Published: 2019

Journal Articles

A Novel Cycs Missense Mutation in the α-Helix of the Cycs C-Terminal Domain Causes Non-Syndromic Thrombocytopenia

Yuri Uchiyama, MD PhD, Kunio Yanagisawa, MD PhD, Shinji Kunishima, PhD, Masaaki Shiina, MD PhD, Yoshiyuki Ogawa, MD PhD, Mitsuko Nakashima, MD PhD, Satoko Miyatake, MD PhD, Satomi Mitsuhashi, MD PhD, Atsushi Takata, MD PhD, Noriko Miyake, MD PhD, Kazuhiro Ogata, MD PhD, Hiroshi Handa, MD PhD, Naomichi Matsumoto, MD PhD, Takeshi Mizuguchi, MD PhD

Blood (2018) 132 (Supplement 1): 3758.

https://doi.org/10.1182/blood-2018-99-114729

Published: 2018

Journal Articles

Identification of a Novel Heterozygous Mutation ( c.2213T>G;p.Leu738Arg ) in Platelet Glycoprotein ITGB3 gene in a Patient with Glanzmann's Thrombasthenia

Candido E. Rivera, MD, Prakash Vishnu, MD, Gretchen Schaef Johns, MD, Rajiv K. Pruthi, M.B.B.S., Dong Chen, MD PhD

Blood (2018) 132 (Supplement 1): 1158.

https://doi.org/10.1182/blood-2018-99-117995

Published: 2018

Journal Articles

Symptomatic Hemoglobin New Mexico and a Case of Therapeutic Benefit with Acetazolamide

Ahmed Ayad, MD, Sara Nofal, MD, Crystal Jobson, MD, Yuval Raizen, MD, Mona Lisa Alattar, MD

Blood (2018) 132 (Supplement 1): 4918.

https://doi.org/10.1182/blood-2018-99-119250

Published: 2018

Journal Articles

Optimized FVIII-Domain-Based Chimeric Antigen Receptors to Specifically Target FVIII Inhibitor-Producing B Cells in Hemophilia a

Vijay Bhoj, MD PhD, Lucy Li, Benjamin J. Samelson-Jones, MD PhD, Bhavya S Doshi, MD, Christoph Ellebrecht, MD, Aimee Payne, MD PhD, Valder R Arruda, MD PhD, Michael C. Milone, MD PhD

Blood (2018) 132 (Supplement 1): 2196.

https://doi.org/10.1182/blood-2018-99-120031

Published: 2018

Journal Articles

Patients with CD3G mutations reveal a role for human CD3γ in T reg diversity and suppressive function

Jared H. Rowe, Ottavia M. Delmonte, Sevgi Keles, Brian D. Stadinski, Adam K. Dobbs, Lauren A. Henderson, Yasuhiro Yamazaki, Luis M. Allende, Francisco A. Bonilla, Luis I. Gonzalez-Granado, Seyma Celikbilek Celik, Sukru N. Guner, Hasan Kapakli, Christina Yee, Sung-Yun Pai, Eric S. Huseby, Ismail Reisli, Jose R. Regueiro, Luigi D. Notarangelo

Blood (2018) 131 (21): 2335–2344.

https://doi.org/10.1182/blood-2018-02-835561

Published: 2018

Includes: Supplemental data

Journal Articles

A Novel Switchable CAR-T Platform for Acute Lymphoblastic Leukemia Treatment

Eduardo Laborda, DVM, PhD, Eric N Hampton, PhD, Sung C Lee, PhD, Ashley K Woods, PhD, Travis S Young, PhD

Blood (2017) 130 (Supplement 1): 3890.

https://doi.org/10.1182/blood.V130.Suppl_1.3890.3890

Published: 2017

Journal Articles

Mitochondria-Targeted Effects of Water-Soluble Polyol-Methanofullerenes on Human Whole Blood Platelets, Lymphocytes and Granulocytes Ex Vivo

Gulzada Tarasova, PhDstudent, Natalia Kalacheva, PhD, Guzel Fazleeva, PhD, Valentina Gubskaya, PhD, Albert Rizvanov, DSc, PhD, Georgi Cherepnev, MD PhD

Blood (2017) 130 (Supplement 1): 4836.

https://doi.org/10.1182/blood.V130.Suppl_1.4836.4836

Published: 2017

Journal Articles

Molecular Mechanism of Intrahepatic Cholestasis in Sickle Cell Disease

Tirthadipa Pradhan, PhD, Prithu Sundd, Egemen Tutuncuoglu, MSc

Blood (2017) 130 (Supplement 1): 4775.

https://doi.org/10.1182/blood.V130.Suppl_1.4775.4775

Published: 2017

Journal Articles

Combined Nanoparticle Delivery of PARP and DNA-PK Inhibition for Multiple Myeloma

Pritesh Patel, MB, CHB, Santosh Misra, PhD, Natalie S. Rodriguez, MS, Gururaja Vulugundam, PhD, Annie L. Oh, MD, Vitalyi Senyuk, PhD, Nadim Mahmud, MBBS, PhD, Damiano Rondelli, MD, Dipanjan Pan

Blood (2017) 130 (Supplement 1): 1809.

https://doi.org/10.1182/blood.V130.Suppl_1.1809.1809

Published: 2017

Journal Articles

Distinct Mechanisms of Receptor Activation Are Associated with CSF3R Gain-of-Function Mutations

Haijiao Zhang, Julia E. Maxson, PhD, Kevin M Watanabe-Smith, PhD, Cody Coblentz, Jeffrey W. Tyner, PhD

Blood (2017) 130 (Supplement 1): 4985.

https://doi.org/10.1182/blood.V130.Suppl_1.4985.4985

Published: 2017

Journal Articles

Cereblon Splicing of Exon 10 Mediates IMiDs Resistance in Multiple Myeloma: Clinical Validation in the CoMMpass Trial

Paola Neri, MD PhD, Ranjan Maity, PhD, Jonathan J Keats, PhD, Ines Tagoug, PhD, Justin Simms, Daniel Auclair, PhD, Sagar Lonial, MD FACP, Nizar J. Bahlis, MD

Blood (2016) 128 (22): 120.

https://doi.org/10.1182/blood.V128.22.120.120

Published: 2016

NARROW

Mutations and Copy Number Gains of the BCL2 Family Members Mediate Resistance to Venetoclax in Multiple Myeloma (MM) Patients

Structural Basis of Vitamin K Antagonism

Functional Interactions between Transcription Factors Involved in Myeloma Pathogenesis - Biological and Therapeutic Implications

Identification of a Heme Activation Site on the MD-2/TLR4 Complex

Interactome Analysis of APOBEC3B in Multiple Myeloma

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

NOTCH2 Contributes to Venetoclax Resistance in Chronic Lymphocytic Leukemia

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

GDF1 Is a Regulator of Sphingolipid Metabolism in Acute Myeloid Leukemia

A Novel Cycs Missense Mutation in the α-Helix of the Cycs C-Terminal Domain Causes Non-Syndromic Thrombocytopenia

Identification of a Novel Heterozygous Mutation ( c.2213T>G;p.Leu738Arg ) in Platelet Glycoprotein ITGB3 gene in a Patient with Glanzmann's Thrombasthenia

Symptomatic Hemoglobin New Mexico and a Case of Therapeutic Benefit with Acetazolamide

Optimized FVIII-Domain-Based Chimeric Antigen Receptors to Specifically Target FVIII Inhibitor-Producing B Cells in Hemophilia a

Patients with CD3G mutations reveal a role for human CD3γ in T reg diversity and suppressive function

A Novel Switchable CAR-T Platform for Acute Lymphoblastic Leukemia Treatment

Mitochondria-Targeted Effects of Water-Soluble Polyol-Methanofullerenes on Human Whole Blood Platelets, Lymphocytes and Granulocytes Ex Vivo

Molecular Mechanism of Intrahepatic Cholestasis in Sickle Cell Disease

Combined Nanoparticle Delivery of PARP and DNA-PK Inhibition for Multiple Myeloma

Distinct Mechanisms of Receptor Activation Are Associated with CSF3R Gain-of-Function Mutations

Cereblon Splicing of Exon 10 Mediates IMiDs Resistance in Multiple Myeloma: Clinical Validation in the CoMMpass Trial

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American Society of Hematology

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American Society of Hematology

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